H. Sprecher

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Phospholipid fatty acid remodeling in mammalian cells.

J. MacDonald, H. Sprecher, James I.S. MacDonald, 1991, Biochimica et biophysica acta.

Unidimensional thin-layer chromatography of phospholipids on boric acid-impregnated plates.

H. Sprecher, J. Fine, 1982, Journal of lipid research.

Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.

Y. Assaraf, J. Schornagel, D. Priest, 1997, Advances in enzyme regulation.

Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid.

A. A. Spector, H. Sprecher, E. Hurt, 1995, Journal of lipid research.

High sensitivity negative ion GC-MS method for detection of desaturated and chain-elongated products of deuterated linoleic and linolenic acids.

H. Sprecher, N. Salem, R. Pawlosky, 1992, Journal of lipid research.

THE ACTIVITY OF PARTIAL REACTIONS IN THE CHAIN ELONGATION OF PALMITOYL‐CoA AND STEAROYL‐CoA BY MOUSE BRAIN MICROSOMES

N. Baumann, H. Sprecher, J. Bernert, 1979, Journal of neurochemistry.

Metabolism of long-chain polyunsaturated fatty acids in isolated cardiac myocytes.

T. Hagve, H. Sprecher, 1989, Biochimica et biophysica acta.

A Structurally Altered Human Reduced Folate Carrier with Increased Folic Acid Transport Mediates a Novel Mechanism of Antifolate Resistance*

G. Peters, Y. Assaraf, J. Schornagel, 1998, The Journal of Biological Chemistry.

Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells.

Y. Assaraf, G. Jansen, I. Goldman, 2000, European journal of biochemistry.

Regulation of the Biosynthesis of 4,7,10,13,16,19-Docosahexaenoic Acid*

B. S. Mohammed, H. Sprecher, D. Luthria, 1996, The Journal of Biological Chemistry.

Chain elongation and desaturation of eicosapentaenoate to docosahexaenoate and phospholipid labeling in the rat retina in vivo.

H. Bazan, N. Bazan, H. Sprecher, 1982, Biochimica et biophysica acta.

Very long chain (C24 to C36) polyenoic fatty acids of the n-3 and n-6 series in dipolyunsaturated phosphatidylcholines from bovine retina.

H. Sprecher, M. Aveldaño, 1987, The Journal of biological chemistry.

Alteration of Mitochondrial Gene Expression and Disruption of Respiratory Function by the Lipophilic Antifolate Pyrimethamine in Mammalian Cells (*)

Y. Assaraf, M. Tzukerman, G. Eytan, 1995, The Journal of Biological Chemistry.

An analysis of partial reactions in the overall chain elongation of saturated and unsaturated fatty acids by rat liver microsomes.

H. Sprecher, J. Bernert, 1977, The Journal of biological chemistry.

Metabolism of polyunsaturated fatty acids by an (n - 6)-lipoxygenase associated with human ejaculates.

E. Oliw, H. Sprecher, 1989, Biochimica et biophysica acta.

Oxidation of docosahexaenoic acid by rat liver microsomes.

R. Murphy, H. Sprecher, R. Baker, 1984, The Journal of biological chemistry.

Binding of carbamyl-platelet-activating factor to the Raji lymphoblast platelet-activating factor receptor.

J. Travers, H. Sprecher, R. Fertel, 1992, International journal of immunopharmacology.

Manipulation of platelet aggregation by prostaglandins and their fatty acid precursors: pharmacological basis for a therapeutic approach.

P. Needleman, H. Sprecher, A. Raz, 1980, Prostaglandins.

High affinity esterification of eicosanoid precursor fatty acids by platelets.

E. Neufeld, P. Majerus, H. Sprecher, 1983, The Journal of clinical investigation.

2-alkenyl-4,4-dimethyloxazolines as derivatives for the structural elucidation of iosmeric unsaturated fatty acids

H. Sprecher, D. Luthria, 1993, Lipids.

2,4-Dienoyl-coenzyme A reductase deficiency: a possible new disorder of fatty acid oxidation.

D. Millington, C. Roe, H. Sprecher, 1990, The Journal of clinical investigation.

Conferences, Symposia, and Reports: The 1st Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL) Fatty Acids and Lipids from Cell Biology to Human Disease

W. Harris, B. Koletzko, R. Mensink, 1994 .

An in vitro model for essential fatty acid deficiency: HepG2 cells permanently maintained in lipid-free medium.

E. Furth, E. Fisher, M. Laposata, 1992, Journal of lipid research.

Very long chain acyl-CoA dehydrogenase deficiency: successful treatment of acute cardiomyopathy.

C. Roe, H. Sprecher, C. Vianey‐Saban, 1996, Biochemical and molecular medicine.

High-pressure liquid chromatography of underivatized fatty acids, hydroxy acids, and prostanoids having different chain lengths and double-bond positions.

L. Horrocks, H. Sprecher, M. Aveldaño, 1982, Methods in enzymology.

CHAPTER 17 – COMPARISON OF OMEGA–3 AND OMEGA–6 FATTY ACID METABOLISM1

H. Sprecher, 1986 .

An evaluation of the relationship between arachidonic acid lipoxygenation and human neutrophil degranulation.

H. Sprecher, F. Sun, J. C. Mcguire, 1981, Clinical immunology and immunopathology.

Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin endoperoxide synthase and by cytochrome P450 monooxygenase: structure and mechanism of formation of major metabolites.

M. Hamberg, E. Oliw, H. Sprecher, 1993, Archives of biochemistry and biophysics.

Synthesis of two hydroxy fatty acids from 7,10,13,16,19-docosapentaenoic acid by human platelets.

H. Sprecher, M. M. Careaga, M. Careaga, 1984, The Journal of biological chemistry.

Elongation of long-chain fatty acids.

H. Sprecher, Yung-Sheng Huang, S. Pereira, 2004, Progress in lipid research.

Arachidonate 15-lipoxygenase in human corneal epithelium and 12- and 15-lipoxygenases in bovine corneal epithelium: comparison with other bovine 12-lipoxygenases.

H. Sprecher, E. Oliw, L. Hörnsten, 1994, Biochimica et biophysica acta.

The effect of a fish oil diet on the fatty acid composition of individual phospholipids and eicosanoid production by rat platelets

H. Sprecher, M. Careaga-Houck, 1989, Lipids.

Interactions between the metabolism of n‐3 and n‐6 fatty acids

H. Sprecher, 1989, Journal of internal medicine. Supplement.

(N-3) and (N-6) Fatty Acid Metabolism

H. Sprecher, 1989 .

Formation of 8-hydroxyhexadecatrienoic acid by vascular smooth muscle cells.

A. A. Spector, H. Sprecher, P. Figard, 1987, Prostaglandins.

Metabolism of icosa-5,11,14-trienoic acid in human platelets and the inhibition of arachidonic acid metabolism in human platelets by icosa-5,8,14-triynoic and icosa-5,11,14-triynoic acids.

H. Sprecher, R. Evans, 1985, Prostaglandins.

Prostaglandin E2‐like activity of 20:3n‐9 platelet lipoxygenase end‐product

M. Lagarde, H. Sprecher, S. Renaud, 1985, FEBS letters.

16 – The Mechanisms of Fatty Acid Chain Elongation and Desaturation in Animals

H. Sprecher, 1983 .

Inhibition of prostaglandin biosynthesis by triynoic acids.

D. Cornwell, H. Sprecher, R. Panganamala, 1976, Prostaglandins.

The metabolism of platelet-activating factor in human T-lymphocytes.

J. Travers, H. Sprecher, R. Fertel, 1990, Biochimica et biophysica acta.

Functional Characterization of Δ3,Δ2-Enoyl-CoA Isomerases from Rat Liver*

B. Geisbrecht, S. Gould, H. Sprecher, 2002, The Journal of Biological Chemistry.

Long-chain acyl-CoA dehydrogenase is a key enzyme in the mitochondrial beta-oxidation of unsaturated fatty acids.

J. Vockley, H. Sprecher, H. Schulz, 2000, Biochimica et biophysica acta.

Effects of a fish oil diet on the metabolism of endogenous (n-6) and (n-3) fatty acids in rat neutrophils.

H. Sprecher, M. Careaga-Houck, 1990, Biochimica et biophysica acta.

Leukotriene B formation by neutrophils from essential fatty acid-deficient rats.

H. Sprecher, S. Prescott, W. Stenson, 1984, The Journal of biological chemistry.

Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway.

H. Sprecher, B. Jakschik, A. Morrison, 1983, The Journal of biological chemistry.

Distribution of arachidonic acid in choline- and ethanolamine-containing phosphoglycerides in subfractionated human neutrophils.

J. MacDonald, H. Sprecher, 1989, The Journal of biological chemistry.

The metabolism of (n-3) and (n-6) fatty acids and their oxygenation by platelet cyclooxygenase and lipoxygenase.

H. Sprecher, Howarard Sprecher, 1986, Progress in lipid research.

Regulation of the biosynthesis of 22:5n-6 and 22:6n-3: A complex intracellular process

H. Sprecher, Qi Chen, F. Q. Yin, 2007, Lipids.

Polyunsaturated fatty acid biosynthesis: a microsomal-peroxisomal process.

H. Sprecher, Q. Chen, 1999, Prostaglandins, leukotrienes, and essential fatty acids.

Fatty acid specificity in the inhibition of cell proliferation and its relationship to lipid peroxidation and prostaglandin biosynthesis

G. Milo, D. Cornwell, H. Sprecher, 1982, Lipids.

An update on the pathways of polyunsaturated fatty acid metabolism.

H. Sprecher, 1999, Current opinion in clinical nutrition and metabolic care.

Substrate specificity of the agonist-stimulated release of polyunsaturated fatty acids from vascular endothelial cells.

H. Sprecher, M. D. Rosenthal, M. C. García, 1989, Archives of biochemistry and biophysics.

Effect of a fish oil diet on the composition of rat neutrophil lipids and the molecular species of choline and ethanolamine glycerophospholipids.

H. Sprecher, M. Careaga-Houck, Howard Sprecher, 1989, Journal of lipid research.

Metabolism of 6,9,12-octadecatrienoic acid and 6,9,12,15-octadecatetraenoic acid by rat hepatocytes.

H. Sprecher, A. Voss, Howard Sprecher, 1988, Biochimica et biophysica acta.

Stearidonic acid, an inhibitor of the 5-lipoxygenase pathway. A comparison with timnodonic and dihomogammalinolenic acid

P. Finot, H. Sprecher, M. Guichardant, 1993, Lipids.

Metabolism of polyunsaturated (n-3) fatty acids by monkey seminal vesicles: isolation and biosynthesis of omega-3 epoxides.

E. Oliw, H. Sprecher, 1991, Biochimica et biophysica acta.

Long-chain acyl-coenzyme A synthetase from rat brain microsomes. Kinetic studies using [1-14C]docosahexaenoic acid substrate.

N. Bazan, H. Sprecher, T. S. Reddy, 1984, European journal of biochemistry.

De novo biosynthesis of docosahexaenoyl-phosphatidic acid in bovine retinal microsomes.

H. Bazan, N. Bazan, H. Sprecher, 1984, Biochimica et biophysica acta.

Free Fatty Acid Patterns of Human Maternal Plasma, Perfused Placenta and Umbilical Cord Plasma

H. Sprecher, A. Robertson, J. Wilcox, 1968, Nature.

Triene prostaglandins: prostaglandin D3 and icosapentaenoic acid as potential antithrombotic substances.

P. Needleman, F. Fitzpatrick, H. Sprecher, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Total synthesis and spectral characterization of 5,8,14-icosatrienoic acid and 5,11,14-icosatrienoic acid and their acetylenic analogues.

H. Sprecher, R. Evans, 1985, Chemistry and physics of lipids.

Double Bond Removal from Odd-numbered Carbons during Peroxisomal β-Oxidation of Arachidonic Acid Requires both 2,4-Dienoyl-CoA Reductase and Δ3,5,Δ2,4-Dienoyl-CoA Isomerase (*)

H. Sprecher, D. Luthria, S. Baykousheva, 1995, The Journal of Biological Chemistry.

Biochemistry of essential fatty acids.

H. Sprecher, Howard Sprecher, 1981, Progress in lipid research.

Studies on the incorporation and transacylation of various fatty acids in choline and ethanolamine-containing phosphoacylglycerol subclasses in human neutrophils.

J. MacDonald, H. Sprecher, 1989, Biochimica et biophysica acta.

Retroconversion and delta 4 desaturation of docosatetraenoate (22:4(n-6)) and docosapentaenoate (22:5(n-3)) by human cells in culture.

M. Jones, H. Sprecher, M. D. Rosenthal, 1991, Biochimica et biophysica acta.

Metabolism of 4,7,10,13,16-docosapentaenoic acid by human platelet cyclooxygenase and lipoxygenase.

H. Sprecher, M. Milks, 1985, Biochimica et biophysica acta.

Synthesis of hydroxy fatty acids from 4, 7, 10, 13, 16, 19-[1-14C] docosahexaenoic acid by human platelets.

H. Sprecher, M. Aveldaño, 1983, The Journal of biological chemistry.

Mechanism underlying the inhibition of platelet aggregation by eicosapentaenoic acid and its metabolites.

P. Needleman, H. Sprecher, M. 0. Whitaker, 1980, Advances in prostaglandin and thromboxane research.

A REVIEW OF HUMAN PLACENTAL LIPID METABOLISM AND TRANSPORT

H. Sprecher, A. Robertson, 1968, Acta paediatrica Scandinavica.

Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney.

P. Needleman, H. Sprecher, F. Sun, 1982, The Journal of biological chemistry.

Metabolism of 15-hydroxy-5,8,11,13-eicosatetraenoic acid by MOLT-4 cells and blood T-lymphocytes.

J. Travers, H. Sprecher, R. Fertel, 1990, The Journal of biological chemistry.

Selective acyl transfer in the reacylation of brain glycerophospholipids. Comparison of three acylation systems for 1-alk-1'-enylglycero-3-phosphoethanolamine, 1-acylglycero-3-phosphoethanolamine and 1-acylglycero-3-phosphocholine in rat brain microsomes.

K. Waku, T. Sugiura, H. Sprecher, 1989, Biochimica et Biophysica Acta.

Rapid Publication 2 , 4-Dienoyl-Coenzyme A Reductase Deficiency : A Possible New Disorder of Fatty Acid Oxidation

D. Millington, C. Roe, H. Sprecher, 2013 .

The total synthesis and metabolism of 4-decenoate, dodeca-3,6-dienoate, tetradeca-5,8-dienoate and hexadeca-7,10-dienoate in the fat-deficient rat

H. Sprecher, 2006, Lipids.

The organic synthesis of unsaturated fatty acids.

H. Sprecher, 1978, Progress in the chemistry of fats and other lipids.

The synthesis and metabolism of hexadeca-4,7,10-trienoate, eicosa-8,11,14-trienoate, docosa-10,13,16-trienoate and docosa-6,9,12,15-tetraenoate in the rat.

H. Sprecher, 1968, Biochimica et biophysica acta.

The total synthesis and metabolism of 7,10,13,16-docosatetraenoate in the rat.

H. Sprecher, 1967, Biochimica et biophysica acta.

Active synthesis of C24:5, n-3 fatty acid in retina.

H. Sprecher, N. Rotstein, G. L. Pennacchiotti, 1996, The Biochemical journal.

Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets.

L. Horrocks, H. Sprecher, M. Vanrollins, 1985, Biochimica et biophysica acta.

The metabolic transformations of columbinic acid and the effect of topical application of the major metabolites on rat skin.

P. Needleman, W. Elliott, H. Sprecher, 1985, The Journal of biological chemistry.

Arachidonic acid, 5,8,11-eicosatrienoic acid and 5,8,11,14, 17-eicosapentaenoic acid. Dietary manipulation of the levels of these acids in rat liver and platelet phospholipids and their incorporation into human platelet lipids.

H. Sprecher, T. Weiner, 1984, Biochimica et biophysica acta.

Synthesis of ethyl arachidonate-19,19,20,20-d4 and ethyl dihomo-γ-linolenate-19,19,20,20-d4

H. Sprecher, D. Luthria, 1993, Lipids.

The influence of dietary alterations, fasting and competitive interactions on the microsomal chain elongation of fatty acids.

H. Sprecher, 1974, Biochimica et biophysica acta.

Paradoxical conservation of cardiac and renal arachidonate content in essential fatty acid deficiency.

P. Needleman, H. Sprecher, J. Lefkowith, 1985, The Journal of biological chemistry.

The effect of anoxia on lipid metabolism in isolated adult rat cardiac myocytes.

T. Hagve, H. Sprecher, C. Hohl, 1990, Journal of molecular and cellular cardiology.

Calcium-dependent oxidation of 5,8,11-icosatrienoic acid by the cyclooxygenase enzyme system.

P. Needleman, W. Elliott, H. Sprecher, 1986, The Journal of biological chemistry.

Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids.

B. S. Mohammed, H. Sprecher, H Sprecher, 1995, Journal of lipid research.

Metabolism of highly unsaturated n-3 and n-6 fatty acids.

H. Sprecher, 2000, Biochimica et biophysica acta.

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

H. Sprecher, M. Reinhart, A. Voss, 1991, The Journal of biological chemistry.

Studies to determine if rat liver contains chain-length-specific acyl-CoA 6-desaturases.

B. S. Mohammed, M. Geiger, H. Sprecher, 1993, Biochimica et biophysica acta.

Studies to determine the role rates of chain elongation and desaturation play in regulating the unsaturated fatty acid composition of rat liver lipids.

H. Sprecher, J. Bernert, 1975, Biochimica et biophysica acta.

The absence of an 8-desaturases in rat liver: a reevaluation of optional pathways for the metabolism of linoleic and linolenic acids.

H. Sprecher, C. J. Lee, 1975, Biochimica et biophysica acta.

An in vitro and in vivo study of the conversion of eicosa-11,14-dienoic acid to eicosa-5,11,14-trienoic acid and of the conversion of eicosa-11-enoic acid to eicosa-5,11-dienoic acid in the rat.

H. Sprecher, D. Ullman, 1971, Biochimica et biophysica acta.

An in vitro studyof the effects of linoleic, eicosa-8,11,14-trienoic and arachidonic acids on the desaturation of stearic, oleic and eicosa-8,11-dienoic acid

H. Sprecher, D. Ullman, 1971 .

[46] Synthesis of radiolabeled fatty acids

H. Sprecher, S. Sankarappa, 1982 .

The total synthesis and characterization of six methyl branched isomers of 8,11,14-eicosatrienoic acid.

H. Sprecher, U. H. Do, 1976, Chemistry and physics of lipids.

A study of some of the factors involved in regulating the conversion of octadeca-8,11-dienoate to eicosa-4,7,10,13-tetraenoate in the rat.

H. Sprecher, J. Budny, 1971, Biochimica et biophysica acta.

On the mechanism of action of xanthine oxidase. Evidence in support of an oxo transfer mechanism in the molybdenum-containing hydroxylases.

R. Hille, H. Sprecher, 1987, The Journal of biological chemistry.

Fatty acids as sources of potential "magic bullets" for the modification of platelet and vascular function.

P. Needleman, H. Sprecher, B. Jakschik, 1981, Progress in lipid research.

Structure of an Optically Active Allene-containing Tetraester Triglyceride Isolated from the Seed Oil of Sapium sebiferum*

H. Sprecher, R. Holman, M. Barber, 1965 .

Evidence for Intermediate Channeling in Mitochondrial -Oxidation (*)

C. Roe, H. Sprecher, H. Schulz, 1995, The Journal of Biological Chemistry.

Substrate specificity studies on the malonyl-CoA-dependent chain elongation of all-cis polyunsaturated fatty acids by rat liver microsomes.

H. Sprecher, S. Ludwig, 1979, Archives of biochemistry and biophysics.

An in vitro study of the effects of dietary alteration and fasting on the desaturation of palmitic, stearic eicosa-8,11-dienoic and eicosa-8,11,14-trienoic acids.

H. Sprecher, C. J. Lee, 1971, Biochimica et biophysica acta.

The biosynthesis and turnover of different molecular species of rat testicular choline phosphoglycerides and triacylglycerols following intratesticular injection with (1(3)-14C)glycerol.

H. Sprecher, M. Duffy, 1975, Biochimica et biophysica acta.

Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties.

J. Ferrendelli, P. Needleman, H. Sprecher, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Neonatal polyunsaturated fatty acid metabolism

H. Sprecher, S. Innis, D. Hachey, 1999, Lipids.

Active labeling of phosphatidylcholines by [1-14C]docosahexaenoate in isolated photoreceptor membranes.

H. Sprecher, M. Aveldaño, N. M. Guisto, 1986, Biochimica et biophysica acta.

Human placental lipid metabolism. III. Synthesis and hydrolysis of phospholipids

H. Sprecher, A. Robertson, 1967, Lipids.

Feeding studies designed to determine whether competitive reactions between acids of the oleate and linoleate families for desaturation chain elongation or incorporation regulate the fatty acid composition of rat liver lipids.

H. Sprecher, 1974, Biochimica et biophysica acta.

Isolation of two novel E prostaglandins in human seminal fluid.

M. Hamberg, E. Oliw, H. Sprecher, 1986, The Journal of biological chemistry.

Biosynthesis of a novel prostaglandin. Δ17 -PGE1, in the ram

M. Hamberg, E. Oliw, H. Sprecher, 1986 .

Metabolism of 8,11,14,17-eicosatetraenoic acid by human platelet lipoxygenase and cyclooxygenase.

H. Sprecher, M. M. Careaga, M. Careaga, 1987, Biochimica et biophysica acta.

Analogues of arachidonic acid used to evaluate structural determinants of prostaglandin receptor and enzyme specificities.

P. Needleman, H. Sprecher, L. Leduc, 1981, Molecular pharmacology.

Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds.

H. Sprecher, F. Sun, W. Kunau, 1981, Prostaglandins.

Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid.

L. Meijer, A. Brash, J. Maclouf, 1986, The Journal of biological chemistry.

Studies on the preparation and analysis of glyceryl ether derivatives and the isolation and reductive ozonolysis of unsaturated glyceryl ethers

D. Cornwell, H. Sprecher, S. Ramachandran, 1968, Lipids.

Peroxisomal beta-oxidation of polyunsaturated long chain fatty acids in human fibroblasts. The polyunsaturated and the saturated long chain fatty acids are retroconverted by the same acyl-CoA oxidase.

R. Wanders, B. Poll-The, T. Hagve, 1993, Scandinavian journal of clinical and laboratory investigation. Supplementum.

Estrogen-induced Production of a Peroxisome Proliferator-activated Receptor (PPAR) Ligand in a PPARγ-expressing Tissue*

H. Sprecher, P. Kolattukudy, Hongwen Ma, 1998, The Journal of Biological Chemistry.

Studies to determine if rat liver contains multiple chain elongating enzymes.

H. Sprecher, D. Luthria, 1997, Biochimica et biophysica acta.

New advances in fatty-acid biosynthesis.

H. Sprecher, 1996, Nutrition.

The questionable role of a microsomal °8 acyl-CoA-dependent desaturase in the biosynthesis of polyunsaturated fatty acids

H. Sprecher, Qi Chen, F. Q. Yin, 2000, Lipids.

Peroxisomal‐microsomal communication in unsaturated fatty acid metabolism

H. Sprecher, D. Luthria, S. Baykousheva, 1995, FEBS letters.

Reevaluation of the pathway for the metabolism of 7,10,13, 16-docosatetraenoic acid to 4,7,10,13,16-docosapentaenoic acid in rat liver.

B. S. Mohammed, M. Geiger, H. Sprecher, 1995, Archives of Biochemistry and Biophysics.

Arachidonic acid formed by peroxisomal beta-oxidation of 7,10,13,16-docosatetraenoic acid is esterified into 1-acyl-sn-glycero-3-phosphocholine by microsomes.

H. Sprecher, D. Luthria, S. Baykousheva, 1994, Journal of Biological Chemistry.

Metabolism of cholesterol esters in the human placenta.

H. Sprecher, A. Robertson, C. Dobbs, 1969, Biologia neonatorum. Neo-natal studies.

D. Cornwell, H. Sprecher, H. Sharma, 1974, Prostaglandins.

Enzyme activities affecting tissue lipid fatty acid composition.

H. Sprecher, 1991, World review of nutrition and dietetics.

Biosynthetic pathways of polyunsaturated fatty acids.

H. Sprecher, 1977, Advances in experimental medicine and biology.

Enzymatic studies on the mechanism of the retroconversion of C22-polyenoic fatty acids to their C20-homologues.

W. Stoffel, H. Sprecher, Eker, 1970, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid.

B. S. Mohammed, H. Sprecher, D. Luthria, 1997, The Biochemical journal.

The roles of anabolic and catabolic reactions in the synthesis and recycling of polyunsaturated fatty acids.

H. Sprecher, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

Peroxisomes Contain Δ3,5,Δ2,4-Dienoyl-CoA Isomerase and thus Possess All Enzymes Required for the β-Oxidation of Unsaturated Fatty Acids by a Novel Reductase-Dependent Pathway

H. Sprecher, H. Schulz, Xue‐Ying He, 1995 .

A comparison of the metabolism of [3-14C]-labeled 22- and 24-carbon (n-3) and (n-6) unsaturated fatty acids by rat testes and liver.

H. Sprecher, Q. Chen, F. Q. Yin, 1999, Biochimica et biophysica acta.

Analysis of the acyl-CoAs that accumulate during the peroxisomal beta-oxidation of arachidonic acid and 6,9,12-octadecatrienoic acid.

H. Sprecher, D. Luthria, Q. Chen, 1998, Archives of biochemistry and biophysics.

Differences in the interconversion between 20- and 22-carbon (n - 3) and (n - 6) polyunsaturated fatty acids in rat liver.

H. Sprecher, M. Reinhart, A. Voss, 1992, Biochimica et biophysica acta.

Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate.

H. Sprecher, D. Luthria, Q. Chen, 1997, Biochemical and biophysical research communications.

Differences in the regulation of biosynthesis of 20- versus 22-carbon polyunsaturated fatty acids.

B. S. Mohammed, H. Sprecher, D. Luthria, 1995, Prostaglandins, leukotrienes, and essential fatty acids.

Essential Fatty Acids: Then and Now

H. Sprecher, 2003 .

Pathways for the biosynthesis of polyunsaturated fatty acids

H. Sprecher, D. Luthria, S. Baykousheva, 1996 .

Evaluation of superoxide anion and singlet oxygen in the biosynthesis of prostaglandins from eicosa-8,11,14-trienoic acid.

D. Cornwell, H. Sprecher, R. Panganamala, 1974, Prostaglandins.

Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase.

E. Neufeld, P. Majerus, H. Sprecher, 1984, Journal of lipid research.

Studies on the substrate specificity and inhibition of prostaglandin biosynthesis with methyl branched isomers of eicosa-8, 11, 14-trienoic acid.

H. Sprecher, U. H. Do, 1976, Journal of lipid research.

Fatty acid structural requirements for leukotriene biosynthesis.

P. Needleman, H. Sprecher, A. Sams, 1980, Prostaglandins.

Beta-oxidation of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid by MOLT-4 lymphocytes.

J. Travers, H. Sprecher, R. Fertel, 1992, Archives of biochemistry and biophysics.

22-Carbon polyenoic acids. Incorporation into platelet phospholipids and the synthesis of these acids from 20-carbon polyenoic acid precursors by intact platelets.

H. Sprecher, T. Weiner, 1985, The Journal of biological chemistry.

The effect of bovine serum albumin on partial reactions of palmitoyl-CoA chain elongation by rat liver microsomes.

H. Sprecher, J. Bernert, 1978, Biochimica et biophysica acta.

Factors regulating the elongation of palmitic and stearic acid by rat liver microsomes.

H. Sprecher, J. Bernert, 1979, Biochimica et biophysica acta.

Milk Staling, Phospholipids of Fresh Milk and of Sterile Whole Milk Concentrate

A. M. Swanson, H. Sprecher, F. Strong, 1965 .

Carnitine palmityltransferase activity in the human placenta.

H. Sprecher, A. Robertson, W. Karp, 1971, Biology of the neonate.

The Mycobacterium tuberculosis pks2 Gene Encodes the Synthase for the Hepta- and Octamethyl-branched Fatty Acids Required for Sulfolipid Synthesis*

H. Sprecher, V. Dubey, T. Sirakova, 2001, The Journal of Biological Chemistry.

The isolation of acyl-CoA derivatives as products of partial reactions in the microsomal chain elongation of fatty acids.

H. Sprecher, J. Bernert, 1979, Biochimica et biophysica acta.

THEORY AND APPLICATION OF GAS CHROMATOGRAPHY IN INDUSTRY AND MEDICINE

H. Sprecher, 1969 .

Functional characterization of Delta3,Delta2-enoyl-CoA isomerases from rat liver.

B. Geisbrecht, S. Gould, H. Sprecher, 2002, The Journal of biological chemistry.

Peroxisomes contain delta 3,5,delta 2,4-dienoyl-CoA isomerase and thus possess all enzymes required for the beta-oxidation of unsaturated fatty acids by a novel reductase-dependent pathway.

H. Sprecher, H. Schulz, X. Y. He, 1995, Biochemical and biophysical research communications.

Purification and characterization of the trifunctional beta-oxidation complex from pig heart mitochondria.

H. Sprecher, H. Schulz, X. Y. He, 1993, Archives of biochemistry and biophysics.

The metabolism of 20- and 22-carbon unsaturated acids in rat heart and myocytes as mediated by feeding fish oil

B. S. Mohammed, T. Hagve, H. Sprecher, 1990, Lipids.

Metabolism of (n-6) and (n-3) polyunsaturated fatty acids by human platelets.

H. Sprecher, M. M. Careaga, 1986, Prostaglandins, leukotrienes, and medicine.

Modulation of leukotriene formation by various acetylenic acids.

H. Sprecher, B. Jakschik, S. Sankarappa, 1982, Advances in prostaglandin, thromboxane, and leukotriene research.

Selective inhibitors of platelet lipoxygenase: 4,7,10,13-eicosatetraynoic acid and 5,8,11,14-henicosatetraynoic acid.

H. Sprecher, M. Vanrollins, T. Wilhelm, 1981, Prostaglandins.

Chain elongation of polyunsaturated fatty acids by vascular endothelial cells: Studies with arachidonate analogues

H. Sprecher, M. D. Rosenthal, Martha C. Garcia, 1990, Lipids.

The total synthesis and metabolism of octadeca-5,8,11-trienoate, elicosa-10,13-dienoate and eicosa-7,10,13-trienoate in the fat-deficient rat.

H. Sprecher, 1971, Biochimica et biophysica acta.

PGD3 is the mediator of the antiaggregatory effects of the trienoic endoperoxide PGH3.

P. Needleman, F. Fitzpatrick, H. Sprecher, 1980, Advances in prostaglandin and thromboxane research.

Studies on the relationship of the synthesis of prostaglandins to the biological activity of essential fatty acid.

H. Sprecher, C. Kaltenbach, F. Phillips, 1972, Biochimica et biophysica acta.

The role and manipulation of eicosanoids in essential fatty acid deficiency.

P. Needleman, H. Sprecher, J. Lefkowith, 1986, Progress in lipid research.

A comparison of the specific activities of linoleate and arachidonate in liver, heart and kidney phospholipids after feeding rats ethyl linoleate-9,10,12,13-d4.

H. Sprecher, D. Luthria, 1994, Biochimica et biophysica acta.

Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin H synthase-2 of ovine placental cotyledons: isolation of 13-hydroxy-5,8,11-eicosatrienoic and 11-hydroxy-5,8,12-eicosatrienoic acids.

E. Oliw, H. Sprecher, L. Hörnsten, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Metabolism of 13-hydroxy-9,11-octadecadienoic acid by MOLT-4 lymphocytes.

J. Travers, H. Sprecher, R. Fertel, 1990, Biochimica et biophysica acta.

Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat.

H. Sprecher, D. Luthria, 1995, Journal of lipid research.

Selective incorporation of various C-22 polyunsaturated fatty acids in Ehrlich ascites tumor cells.

K. Waku, W. Lands, H. Sprecher, 1986, Journal of lipid research.

A unique cardiac cytosolic acyltransferase with preferential selectivity for fatty acids that form cyclooxygenase/lipoxygenase metabolites and reverse essential fatty acid deficiency.

P. Needleman, W. Elliott, H. Sprecher, 1985, Biochimica et biophysica acta.

Regulation of the metabolism of linoleic acid to arachidonic acid in rat hepatocytes

H. Sprecher, A. Voss, 1988, Lipids.

Solubilization and partial purification of an enzyme involved in rat liver microsomal fatty acid chain elongation: beta-hydroxyacyl-CoA dehydrase.

H. Sprecher, J. Bernert, 1979, The Journal of biological chemistry.

beta-Hydroxyacyl-coa dehydrase from rat liver microsomes.

H. Sprecher, J. Bernert, 1981, Methods in enzymology.

Characterization of an arachidonic acid-selective acyl-CoA synthetase from murine T lymphocytes.

J. Russell, H. Sprecher, A. Taylor, 1985, Biochimica et biophysica acta.

Studies on the substrate specificity of the fatty acid 5-desaturase by use of methyl branched isomers of eicosa-8,11,14-trienoic acid and the metabolism of these acids in rat liver

H. Sprecher, U. H. Do, 1975 .

Regulation of polyunsaturated fatty acid biosynthesis in the rat.

H. Sprecher, 1972, Federation proceedings.

Inhibition of cytotoxic T lymphocyte-mediated lysis by ETYA: effect independent of arachidonic acid metabolism.

J. Russell, H. Sprecher, A. Morrison, 1985, Journal of immunology.

Potentiating effect of 5,8,11-eicosatrienoic acid on human platelet aggregation

M. Lagarde, H. Sprecher, S. Renaud, 1983, Lipids.

Investigation of beta-oxidation intermediates in normal and MCAD-deficient human fibroblasts using tandem mass spectrometry.

C. Roe, D. Chace, H. Sprecher, 1995, Biochemical and molecular medicine.

The synthesis of 1-14C-arachidonate and 3-14C-docosa-7,10,13,16-tetraenoate

H. Sprecher, 1971, Lipids.

Rapid 2,4-Dienoyl-Coenzyme A Reductase Deficiency: A Possible New Disorder of Fatty Acid Oxidation

B. S. Mohammed, D. Millington, C. Roe, 2022 .

Delta four acetylenic acids - selective inhibitors of the formation of slow reacting substance.

H. Sprecher, B. Jakschik, S. Sankarappa, 1981, Biochemical and biophysical research communications.

Selective inhibitors of platelet arachidonic acid metabolism: aggregation independent of lipoxygenase.

P. Needleman, H. Sprecher, A. Sams, 1982, Advances in prostaglandin, thromboxane, and leukotriene research.