C. Mayne

发表

Microscopic Characterization of Membrane Transporter Function by In Silico Modeling and Simulation.

E. Tajkhorshid, T. Jiang, S. Thangapandian, 2016, Methods in enzymology.

Atomistic Models of General Anesthetics for Use in in Silico Biological Studies

E. Tajkhorshid, C. Mayne, Mark J. Arcario, 2014, The journal of physical chemistry. B.

All-Atom Molecular Dynamics of Virus Capsids as Drug Targets

Klaus Schulten, Juan R. Perilla, Boon Chong Goh, 2016, The journal of physical chemistry letters.

The cellular membrane as a mediator for small molecule interaction with membrane proteins.

E. Tajkhorshid, S. Thangapandian, J. Vermaas, 2016, Biochimica et biophysica acta.

The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

Myles A Brown, S. Chandarlapaty, E. Tajkhorshid, 2018, bioRxiv.

1,25‐Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis

C. Mayne, Justin A. Spanier, C. Hayes, 2011, European journal of immunology.

Vitamin D and estrogen synergy in Vdr-expressing CD4+ T cells is essential to induce Helios+FoxP3+ T cells and prevent autoimmune demyelinating disease

C. Mayne, C. Nelson, Justin A. Spanier, 2015, Journal of Neuroimmunology.

Flexibility Coexists with Shape-Persistence in Cyanostar Macrocycles.

K. Schulten, K. Raghavachari, A. Flood, 2016, Journal of the American Chemical Society.

Altered BAFF‐receptor signaling and additional modifier loci contribute to systemic autoimmunity in A/WySnJ mice

Y. Sasaki, C. Mayne, F. Nashold, 2009, European journal of immunology.

Systemic autoimmunity in BAFF‐R‐mutant A/WySnJ strain mice

C. Mayne, F. Nashold, C. Hayes, 2008, European journal of immunology.

The Role of Micronutrients in Graft-VS.-Host Disease: Immunomodulatory Effects of Vitamins A and D

C. Mayne, Xiao Chen, 2018, Front. Immunol..

Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History.

B. Katzenellenbogen, J. Katzenellenbogen, S. Granick, 2015, Journal of the American Chemical Society.

A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment

R. Houtman, J. Katzenellenbogen, K. Korach, 2020, Science Signaling.

Murine BAFF-receptor residues 168-175 are essential for optimal CD21/35 expression but dispensable for B cell survival.

C. Mayne, C. Hayes, Ian J. Amanna, 2009, Molecular immunology.

Preparation of o-Fluorophenols from Nonaromatic Precursors: Mechanistic Considerations for Adaptation to Fluorine-18 Radiolabeling.

J. Katzenellenbogen, C. Mayne, N. Yasui, 2015, Organic letters.

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

B. Katzenellenbogen, J. Katzenellenbogen, K. Korach, 2016, Science Signaling.

Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.

B. Katzenellenbogen, S. Srinivasan, J. Katzenellenbogen, 2017, Journal of medicinal chemistry.

Supporting Information Macromolecular Crystallography for Synthetic Abiological Molecules : Combining xMDFF and PHENIX for Structure Determination of Cyanostar Macrocycles

Klaus Schulten, Abhishek Singharoy, Amar H Flood, 2015 .

Rapid parameterization of small molecules using the force field toolkit

Klaus Schulten, Jan Saam, Emad Tajkhorshid, 2013, J. Comput. Chem..

Induced and Natural Regulatory T Cells in the Development of Inflammatory Bowel Disease

C. Mayne, Calvin B. Williams, C. Williams, 2013, Inflammatory bowel diseases.

Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs).

J. Katzenellenbogen, C. Mayne, T. Moore, 2010, Molecular endocrinology.

Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

Sarat Chandarlapaty, Christopher G Mayne, B. Katzenellenbogen, 2018, Nature Reviews Cancer.

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

Sarat Chandarlapaty, Emad Tajkhorshid, Patrick R Griffin, 2016, eLife.

Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

B. Katzenellenbogen, S. Chandarlapaty, J. Katzenellenbogen, 2018, Nature Reviews Cancer.

Assembly and Analysis of Cell-Scale Membrane Envelopes

E. Tajkhorshid, J. Vermaas, C. Mayne, 2021, J. Chem. Inf. Model..

A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFNγ to generate self-tolerance and prevent colitis

Y. Iwakura, N. Salzman, C. Mayne, 2018, Mucosal Immunology.

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

S. Chandarlapaty, E. Tajkhorshid, J. Nwachukwu, 2018, bioRxiv.

Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget.

Christopher G Mayne, J. Katzenellenbogen, K. Carlson, 2010, Journal of medicinal chemistry.

A membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the Gloeobacter violaceus ion channel

E. Tajkhorshid, C. Mayne, Mark J. Arcario, 2017, The Journal of Biological Chemistry.

Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands

Rommie E. Amaro, Jacob D. Durrant, Tavina L. Offutt, 2015, J. Chem. Inf. Model..

Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer

B. Katzenellenbogen, S. Chandarlapaty, E. Tajkhorshid, 2021, Molecular Cancer Research.

Adaptive Multilevel Splitting Method for Molecular Dynamics Calculation of Benzamidine-Trypsin Dissociation Time.

Klaus Schulten, Tony Lelièvre, Ivan Teo, 2016, Journal of chemical theory and computation.

Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.

B. Katzenellenbogen, S. Chandarlapaty, J. Katzenellenbogen, 2018, ACS chemical biology.

Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions.

E. Tajkhorshid, Yi Lu, H. Robinson, 2016, Biochemistry.

Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.

E. Tajkhorshid, G. Greene, S. Fanning, 2016, Angewandte Chemie.

A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFNγ to generate self-tolerance and prevent colitis

Y. Iwakura, N. Salzman, C. Mayne, 2018, Mucosal Immunology.

A "cross-stitched" peptide with improved helicity and proteolytic stability.

E. Tajkhorshid, G. Greene, S. Fanning, 2018, Organic & biomolecular chemistry.

The SERM / SERD Bazedoxifene Disrupts ESR 1 Helix 12 to Overcome Acquired Hormone 1 Resistance in Breast Cancer Cells 2

S. Chandarlapaty, E. Tajkhorshid, J. Nwachukwu, 2022 .