Po-Chao Wen

发表

Microscopic Characterization of Membrane Transporter Function by In Silico Modeling and Simulation.

E. Tajkhorshid, T. Jiang, S. Thangapandian, 2016, Methods in enzymology.

Computational characterization of structural dynamics underlying function in active membrane transporters.

Mahmoud Moradi, Jing Li, Emad Tajkhorshid, 2015, Current opinion in structural biology.

Molecular dynamics simulations of membrane channels and transporters.

K. Schulten, E. Tajkhorshid, M. Sotomayor, 2009, Current opinion in structural biology.

The cellular membrane as a mediator for small molecule interaction with membrane proteins.

E. Tajkhorshid, S. Thangapandian, J. Vermaas, 2016, Biochimica et biophysica acta.

Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport

E. Gouaux, E. Tajkhorshid, C. Yoshioka, 2019, Nature.

Visualizing Functional Motions of Membrane Transporters with Molecular Dynamics Simulations

Emad Tajkhorshid, Jing Li, Po-Chao Wen, 2013, Biochemistry.

A microscopic view of the mechanisms of active transport across the cellular membrane

E. Tajkhorshid, S. Thangapandian, Jing Li, 2014 .

Capturing Functional Motions of Membrane Channels and Transporters with Molecular Dynamics Simulation.

E. Tajkhorshid, S. Shaikh, Po-Chao Wen, 2010, Journal of computational and theoretical nanoscience.

Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II

E. Tajkhorshid, Po-Chao Wen, A. Camara, 2020, bioRxiv.

Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer.

S. Chien, J. Guan, D. Schlaepfer, 2011, Nature communications.

Microscopic view of lipids and their diverse biological functions.

Chun Kit Chan, E. Tajkhorshid, N. Trebesch, 2018, Current opinion in structural biology.

Probing key elements of teixobactin–lipid II interactions in membranes† †Electronic supplementary information (ESI) available: Computational methods and supplementary figures. See DOI: 10.1039/c8sc02616e

E. Tajkhorshid, S. Rempe, J. Vanegas, 2018, Chemical science.

Structural Insights into the Lipid A Transport Pathway in MsbA.

E. Tajkhorshid, I. Wilson, R. Stanfield, 2019, Structure.

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

E. Tajkhorshid, Po-Chao Wen, A. Camara, 2017, Front. Physiol..

Structural and functional diversity calls for a new classification of ABC transporters

E. Tajkhorshid, R. Tampé, Yigong Shi, 2020, FEBS letters.

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

Emad Tajkhorshid, Po-Chao Wen, Richard A Stein, 2014, eLife.

On the Origin of Large Flexibility of P-glycoprotein in the Inward-facing State*

Hassane S. Mchaourab, Emad Tajkhorshid, Po-Chao Wen, 2013, The Journal of Biological Chemistry.

Transporter Associated with Antigen Processing The ABCs of Immunology: Structure and Function of TAP, the

Lars V. Schäfer, E. Tajkhorshid, R. Tampé, 2015 .

Conformational Dynamics at the Inner Gate of KcsA during Activation

Mahmoud Moradi, Eduardo Perozo, Emad Tajkhorshid, 2014, Biochemistry.

Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport

E. Gouaux, E. Tajkhorshid, C. Yoshioka, 2019, Nature.

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge

E. Tajkhorshid, W. Metcalf, P. Hergenrother, 2021, Chemical science.

Rationalizing generation of broad spectrum antibiotics with the addition of a primary amine

E. Tajkhorshid, W. Metcalf, P. Hergenrother, 2021 .

Role of internal loop dynamics in antibiotic permeability of outer membrane porins

E. Tajkhorshid, D. Shukla, W. Metcalf, 2022, Proceedings of the National Academy of Sciences.

Investigation of gating in outer membrane porins provides new perspectives on antibiotic resistance mechanisms

E. Tajkhorshid, D. Shukla, W. Metcalf, 2021, bioRxiv.

Conformational coupling of the nucleotide-binding and the transmembrane domains in ABC transporters.

E. Tajkhorshid, Po-Chao Wen, 2009, Biophysical journal.

Transient formation of water-conducting states in membrane transporters

Jing Li, Emad Tajkhorshid, Po-Chao Wen, 2013, Proceedings of the National Academy of Sciences.

Computational Dissection of Membrane Transport at a Microscopic Level.

E. Tajkhorshid, N. Trebesch, M. Shekhar, 2019, Trends in biochemical sciences.

Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2

J. Kowal, E. Tajkhorshid, K. Locher, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Dimer opening of the nucleotide binding domains of ABC transporters after ATP hydrolysis.

Emad Tajkhorshid, Po-Chao Wen, E. Tajkhorshid, 2008, Biophysical journal.

Simulation studies of the mechanism of membrane transporters.

E. Tajkhorshid, Jing Li, S. Shaikh, 2013, Methods in molecular biology.

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge †

E. Tajkhorshid, W. Metcalf, Po-Chao Wen, 2021 .

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge †

E. Tajkhorshid, W. Metcalf, Po-Chao Wen, 2021 .

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge †

E. Tajkhorshid, W. Metcalf, Po-Chao Wen, 2021 .

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge †

E. Tajkhorshid, W. Metcalf, Po-Chao Wen, 2021 .