J. Lameh

发表

Structure and Function of G Protein Coupled Receptors

J. Ramachandran, W. Sadee, S. Maeda, 1990, Pharmaceutical Research.

The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine

A. Levey, H. Meltzer, U. Hacksell, 2004, Psychopharmacology.

Hm1 muscarinic cholinergic receptor internalization requires a domain in the third cytoplasmic loop.

W. Sadee, J. Lameh, M. Philip, 1992, The Journal of biological chemistry.

Phosphorylation and Agonist‐Specific Intracellular Trafficking of an Epitope‐Tagged μ‐Opioid Receptor Expressed in HEK 293 Cells

W. Sadee, J. Lameh, J. Arden, 1995, Journal of neurochemistry.

Activity of opioid ligands in cells expressing cloned mu opioid receptors

J. Lameh, J. David Clark, H. Demirci, 2003, BMC pharmacology.

Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands

D. Bonhaus, J. Lameh, Christopher N. Davis, 2009, BMC pharmacology.

A Constitutively Internalizing and Recycling Mutant of the μ‐Opioid Receptor

W. Sadee, J. Lameh, N. Burford, 1997, Journal of neurochemistry.

Human Muscarinic Cholinergic Receptor Hm1 Internalizes via Clathrin-coated Vesicles*

J. Lameh, L. Tolbert, 1996, The Journal of Biological Chemistry.

Rapid agonist-induced loss of 125I-beta-endorphin opioid receptor sites in NG108-15, but not SK-N-SH neuroblastoma cells.

W. Sadee, J. Lameh, R. Cone, 1991, Life sciences.

Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5.

W. Sadee, K. Ito, J. Lameh, 1999, European journal of biochemistry.

Serine- and threonine-rich domain regulates internalization of muscarinic cholinergic receptors.

W. Sadee, J. Lameh, O. Moro, 1993, The Journal of biological chemistry.

Overlapping multi-site domains of the muscarinic cholinergic Hm1 receptor involved in signal transduction and sequestration.

W. Sadee, J. Lameh, O. Moro, 1994, The Journal of biological chemistry.

Internalization and Down-regulation of Human Muscarinic Acetylcholine Receptor m2 Subtypes

K. Kameyama, W. Sadee, J. Lameh, 1998, The Journal of Biological Chemistry.

Residues Specifically Involved in Down‐Regulation but Not Internalization of the m1 Muscarinic Acetylcholine Receptor

W. Sadee, J. Lameh, N. Burford, 1997, Journal of neurochemistry.

Identification and characterization of novel small molecule Protease Activated Receptor 2 ( PAR 2 ) agonists

K. Schmelzer, J. Lameh, N. Nash, 2008 .

Neuropeptide FF Receptors Have Opposing Modulatory Effects on Nociception

J. Lameh, R. Olsson, Derek Nguyen, 2010, Journal of Pharmacology and Experimental Therapeutics.

Characterization of the RDC1 gene which encodes the canine omolog of a proposed human VIP receptor Expression does not correlate with an increase in VIP binding sites

W. Sadee, J. Lameh, E. M. Blumenthal, 1992, FEBS letters.

Pharmacological and behavioral profile of ACP-103, a novel 5-HT 2A receptor inverse agonist

Robert I. Davis, M. Geyer, D. Weiner, 2006 .

Differential regulation of muscarinic M1 and M3 receptors by a putative phosphorylation domain.

W. Sadee, A. Tobin, J. Lameh, 1999, European journal of pharmacology.

Role of signal transduction in internalization of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein.

R. Nissenson, J. Lameh, Z. Huang, 1999, Endocrinology.

Discovery of potential antipsychotic agents possessing pro-cognitive properties

F. Piu, K. Mcfarland, D. Bonhaus, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Characterization of novel benzodiazepine ligands in Spodotera frugiperda (Sf-9) insect cells

G. Loew, J. Lameh, D. Clark, 2001, Neuroscience Letters.

Pharmacological profiles of opioid ligands at Kappa opioid receptors

T. Delorey, J. Lameh, J. Clark, 2006, BMC pharmacology.

The muscarinic acetylcholine receptors

W. Sadee, J. Lameh, P. Högger, 1996 .

Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists.

A. Scully, J. Lameh, N. Nash, 2009, Journal of medicinal chemistry.

Pharmacology of N-desmethylclozapine.

D. Weiner, D. Bonhaus, J. Lameh, 2007, Pharmacology & therapeutics.

Application of biomarkers in oncology clinical trials

A. Siva, J. Lameh, S. Tangri, 2015 .

Mapping the Ligand Binding Pocket of the Human Muscarinic Cholinergic Receptor Hml: Contribution of Tyrosine-82

W. Sadee, J. Lameh, M. Philip, 1992, Pharmaceutical Research.

Pharmacology of polymorphic variants of the human 5-HT1A receptor.

U. Hacksell, D. Weiner, M. Brann, 2004, Biochemical pharmacology.

Nucleoside uptake and membrane fluidity studies on N-trifluoroacetyladriamycin-14-O-hemiadipate-treated human leukemia and lymphoma cells.

J. Lameh, M. Israel, L. Chuang, 1989, Cancer research.

Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti–PD-1 Therapies in Metastatic Melanoma

J. Witte, T. Ho, J. Kim, 2018, Clinical Cancer Research.

Identification and Characterization of Novel Small-Molecule Protease-Activated Receptor 2 Agonists

K. Schmelzer, J. Lameh, N. Nash, 2008, Journal of Pharmacology and Experimental Therapeutics.

Activation profiles of opioid ligands in HEK cells expressing δ opioid receptors

J. Lameh, J. Clark, H. Demirci, 2002, BMC Neuroscience.

Activating and Inactivating Mutations in N- and C-terminal i3 Loop Junctions of Muscarinic Acetylcholine Hm1 Receptors (*)

W. Sadee, J. Lameh, P. Högger, 1995, The Journal of Biological Chemistry.

FLT3 inhibitors added to induction therapy induce deeper remissions.

M. Levis, W. Shi, J. Lameh, 2019, Blood.

Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling.

W. Sadee, J. Lameh, P. Högger, 1993, The Journal of biological chemistry.

Regulation of Cyclic AMP by the μ‐Opioid Receptor in Human Neuroblastoma SH‐SY5Y Cells

W. Sadee, J. Lameh, D. Duan, 1990, Journal of neurochemistry.

AC-260584, an orally bioavailable M1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

K. Mcfarland, D. Bonhaus, J. Lameh, 2010, Neuropharmacology.

Pharmacological and Behavioral Profile of N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl) Carbamide (2R,3R)-Dihydroxybutanedioate (2:1) (ACP-103), a Novel 5-Hydroxytryptamine2A Receptor Inverse Agonist

Ethan S. Burstein, Fabrice Piu, Mark R. Brann, 2006, Journal of Pharmacology and Experimental Therapeutics.

Identification of novel selective V2 receptor non-peptide agonists.

M. Brann, F. Piu, J. Lameh, 2008, Biochemical pharmacology.

Characterization of benzodiazepine receptors in the cerebellum

S. Shafer, D. Meredith, G. Loew, 2000, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Unraveling the identity of benzodiazepine binding sites in rat hipppocampus and olfactory bulb.

S L Shafer, G H Loew, S. Shafer, 2000, European journal of pharmacology.

Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory.

R. Lin, T. Delorey, G. Loew, 2001, European journal of pharmacology.

Morphine Impurity with Opioid Activity Is Identified as 10α-Hydroxymorphine

W. Sadee, B. Gibson, J. Lameh, 1990, Pharmaceutical Research.

Antibody to Epitope Tag Induces Internalization of Human Muscarinic Subtype 1 Receptor

J. Lameh, L. Tolbert, 1998, Journal of Neurochemistry.

Agonist-induced internalization of human ml muscarinic receptor mutants: immunofluorescence confocal microscopy.

J. Lameh, J. Arden, 1996, Proceedings of the Western Pharmacology Society.

Transcutaneous Blood Gas CO2 Monitoring of Induced Ventilatory Depression in Mice

T. Delorey, J. Lameh, J. Clark, 2006, Anesthesia and analgesia.

Interaction among μ-opioid receptors and α2-adrenoceptors on SH-SY5Y human neuroblastoma cells

W. Sadee, J. Lameh, S. Eiger, 1992 .

Abstract 853: Novel quantitative multiplexed PD-1/PD-L1 immunohistochemistry test provides superior prediction of treatment response in melanoma patients

J. Kim, J. Sosman, J. Bordeaux, 2016 .

Activity of opioid ligands in cells expressing cloned mu opioid receptors

J. Lameh, P. Gharagozlou, Hasan Demirci, 2003 .

Activity of opioid ligands in cells expressing cloned mu opioid receptors

J. Lameh, P. Gharagozlou, Hasan Demirci, 2003, BMC pharmacology.

Internalization of the Hm1 muscarinic cholinergic receptor involves the third cytoplasmic loop

W. Sadee, S. Maeda, J. Lameh, 1990, FEBS letters.

AC-260584, an orally bioavailable M1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

K. Mcfarland, D. Bonhaus, J. Lameh, 2010, Neuropharmacology.

Mutational analysis of third cytoplasmic loop domains in G-protein coupling of the HM1 muscarinic receptor.

W. Sadee, J. Lameh, M. Philip, 1992, Biochemical and biophysical research communications.