D. Schirlin

发表

Design, synthesis, and conformational analysis of a novel macrocyclic HIV-protease inhibitor.

B. Podlogar, R. A. Farr, D. Friedrich, 1994, Journal of medicinal chemistry.

Preparative separation of mixtures by mass spectrometry.

P. Štrop, F. Tureček, M. Patek, 2005, Analytical chemistry.

MDL 74147, a novel selective and soluble inhibitor of human renin. Synthesis, structure-activity relationship, species and protease selectivities.

C. Tarnus, D. Schirlin, S. Baltzer, 1992 .

Synthesis of Peptidyl Fluoromethyl Ketones and Peptidyl α-Keto Esters as Inhibitors of Porcine Pancreatic Elastase, Human Neutrophil Elastase, and Rat and Human Neutrophil Cathepsin G.

N. Peet, D. Schirlin, E. Giroux, 1990 .

Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G.

N. Peet, D. Schirlin, E. Giroux, 1990, Journal of medicinal chemistry.

A convenient synthesis of a',-diamino-a,a-difluoroketones, new dipeptide isosteres

D. Schirlin, 1988 .

Synthesis and biological properties of alpha-mono- and alpha-difluoromethyl derivatives of tryptophan and 5-hydroxytryptophan.

D. Schirlin, M. Jung, J. Wagner, 1988, Journal of medicinal chemistry.

Irreversible Inhibition of Gaba-T by Halogenated Analogues of βAlanine

D. Schirlin, S. Baltzer, M. Jung, 1987 .

Useful hydroxylamine derivatives for the synthesis of hydroxamic acids.

C. Mioskowski, C. Tarnus, D. Schirlin, 1992 .

Synthesis of a γ-Hydroxyketone and a 1,4-Diketone, Precursor of Jasmonoids

D. Schirlin, J. Biellmann, 1978 .

General synthesis of polyfunctionalized fluoromethyleneketone retroamides as potential inhibitors of thrombin

D. Schirlin, J. Altenburger, 1991 .

Biochemical and pharmacological evaluation of 2,4-difluorobenzyldimethylsilylmethanamine, a new highly selective inhibitor of monoamine oxidase-B.

D. Schirlin, C. Danzin, M. Petty, 1994, Biochemical Society transactions.

Selective inactivation of MAO-B by benzyl-dimethyl-silyl-methanamines in vitro.

D. Schirlin, C. Danzin, P. Marchal, 1989, Biochemical and biophysical research communications.

Difluoromethyleneketone retroamide, a versatile concept of inactivation of proteolytic enzymes

C. Tarnus, D. Schirlin, S. Baltzer, 1996 .

Rearrangements of the carbanions derived from allyl benzyl thioether

D. Schirlin, J. Biellmann, J. Ducep, 1980 .

α-monofluoromethyl and α-difluoromethyl putrescine as ornithine decarboxylase inhibitors: In vitro and in vivo biochemical properties

D. Schirlin, C. Danzin, P. Bey, 1982 .

Beneficial replacement of the P1 phenylalanine side chain in HIV-1 protease inhibitors of the difluorostatone type

D. Taylor, C. Tarnus, D. Schirlin, 1994 .

Beneficial Replacement of the P1 Phenylalanine Side Chain in HIV-1 Protease Inhibitors of the Difluorostatone Type.

D. Taylor, R. A. Farr, C. Tarnus, 1994 .

Short and unexpectedly potent difluorostatone type inhibitors of HIV-1 protease

C. Tarnus, D. Schirlin, S. Baltzer, 1993 .

Anti-Human Immunodeficiency Virus Activity, Bioavailability and Drug Resistance Profile of the Novel Proteinase Inhibitor MDL 74,695

C. Tarnus, D. Schirlin, T. Brennan, 1997 .

Increased antiviral activity of HIV protease inhibitors of the difluorostatone type bearing (R)-valinol derivatives as novel c-termini

D. Taylor, C. Tarnus, D. Schirlin, 1994 .

Short and Unexpectedly Potent Difluorostatone Type Inhibitors, e.g. (I) , of HIV‐1 Protease.

C. Tarnus, D. Schirlin, S. Baltzer, 1993 .

ω‐Fluoromethyl Analogues of ω‐Amino Acids as Irreversible Inhibitors of 4‐Aminobutyrate: 2‐ Oxoglutarate Aminotransferase

D. Schirlin, P. Casara, M. Jung, 1981, Journal of neurochemistry.

New fluoroketones as human renin inhibitors

C. Tarnus, D. Schirlin, S. Baltzer, 1989, FEBS letters.

Synthesis of New Glycerolipids Linked to Hydroxamate Derivatives Designed for Two-Dimensional Crystallization of Aminopeptidase M

C. Mioskowski, L. Lebeau, D. Schirlin, 1992 .

Alkylation of malonates or schiff base anions with dichlorofluoromethane as a route to α-chlorofluoromethyl or α-fluoromethyl α-amino acids

D. Schirlin, P. Bey, J. Ducep, 1985 .

Synthesis and inhibitory properties of α(chlorofluoromethyl)-α-amino acids, a novel class of irreversible inactivators of decarboxylases

A. Mitschler, D. Schirlin, A. Cian, 1992 .