K. Lee

发表

Antitumor agents. 152. In vitro inhibitory activity of etoposide derivative NPF against human tumor cell lines and a study of its conformation by X-ray crystallography, molecular modeling, and NMR spectroscopy.

Y. L. Zhang, A. Tropsha, A. McPhail, 1994, Journal of medicinal chemistry.

Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.

W. Janzen, R. Kilkuskie, K. Lee, 1994, Journal of natural products.

Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.

K. Lee, M. Kozuka, K. Lee, 1998, Journal of natural products.

The cytotoxic principles of Pseudolarix kaempferi: pseudolaric acid-A and -B and related derivatives.

K. Lee, C. Hu, D. J. Pan, 1990, Planta medica.

Synthesis of novel unnatural amino acid as a building block and its incorporation into an antimicrobial peptide.

K. Lee, J. Oh, 1999, Bioorganic & medicinal chemistry.

Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide.

K. Lee, J. Oh, S. Hong, 1999, Biochemical pharmacology.

Breaks in double-strand DNA by Cu(II) complexes of etoposide (VP-16) and its derivatives, as evaluated by S1 nuclease treatment.

K. Lee, R. Tawa, M. Takami, 1997, Biological & pharmaceutical bulletin.

The Cytotoxic Principles of Prunella vulgaris, Psychotria serpens, and Hyptis capitata: Ursolic Acid and Related Derivatives1

K. Lee, I. Hall, T. Yamagishi, 1988, Planta medica.

Sesquiterpene antitumor agents: inhibitors of cellular metabolism.

T. G. Waddell, K. Lee, K. Lee, 1977, Science.

Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents.

A. McPhail, K. Lee, E. Hamel, 1993, Journal of medicinal chemistry.

Antitumor agents. 134. New shiraiachrome-A- and calphostin-C-related perylene derivatives as cytotoxic and antiviral agents and inhibitors of protein kinase C.

K. Lee, L. M. Ballas, J. B. Jiang, 1992, Journal of medicinal chemistry.

Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents.

K. Lee, Y. Kashiwada, L. Cosentino, 1996, Journal of medicinal chemistry.

Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.

K. Lee, K. Lee, Y. Kashiwada, 1992, Journal of natural products.

In vivo and in vitro effects of helenalin on mouse hepatic microsomal cytochrome P450.

S. Chaney, K. Lee, I. Hall, 1991, Biochemical pharmacology.

In vitro inhibition of mouse hepatic mixed-function oxidase enzymes by helenalin and alantolactone.

S. Chaney, K. Lee, I. Hall, 1989, Biochemical pharmacology.

Acute toxicity of helenalin in BDF1 mice.

S. Chaney, D. Reynolds, K. Lee, 1988, Fundamental and Applied Toxicology.

Binding affinity of Cu(II)-VP-16 (etoposide) complex and its analogues to DNA and hydroxyl radical generation during DNA strand breaks.

K. Lee, R. Tawa, M. Takami, 1998, Bioorganic & medicinal chemistry.

Interaction of novel thiocolchicine analogs with the tubulin isoforms from bovine brain.

K. Lee, E. Hamel, A. Banerjee, 1999, Biochemical and biophysical research communications.

Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.

Y. Cheng, R. Kilkuskie, K. Lee, 1994, Journal of natural products.

Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones.

S. Chaney, K. Lee, A. Grippo, 1988, Anticancer research.

Identification and characterization of the antimicrobial peptide corresponding to C-terminal beta-sheet domain of tenecin 1, an antibacterial protein of larvae of Tenebrio molitor.

K. Lee, J. Oh, S. Hong, 1998, The Biochemical journal.

Two new quassinoids, ailantinols A and B, and related compounds from Ailanthus altissima.

K. Lee, K. Tagahara, N. Fukamiya, 1996, Journal of natural products.

Anti-inflammatory agents III: Structure-activity relationships of brusatol and related quassinoids.

K. Lee, I. Hall, Y. Imakura, 1983, Journal of pharmaceutical sciences.

Antitumor agents XLVI: In vitro effects of esters of brusatol, bisbrusatol, and related compounds on nucleic acid and protein synthesis of P-388 lymphocytic leukemia cells.

K. Lee, I. Hall, M. Okano, 1982, Journal of pharmaceutical sciences.

Antitumor agents 210. Synthesis and evaluation of taxoid-epipodophyllotoxin conjugates as novel cytotoxic agents.

K. Lee, H. Wang, K. Chen, 2001, Bioorganic & medicinal chemistry.

Antitumor agents XLII: Comparison of antileukemic activity of helenalin, brusatol, and bruceantin and their esters on different strains of P-388 lymphocytic leukemic cells.

K. Lee, I. Hall, T. Ibuka, 1981, Journal of pharmaceutical sciences.

Mode of action of sesquiterpene lactones as anti-inflammatory agents.

T. G. Waddell, K. Lee, I. Hall, 1980, Journal of pharmaceutical sciences.

Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release.

K. Lee, Y. Takeda, Y. Takaishi, 2000, Phytochemistry.

Tannins as potent inhibitors of DNA topoisomerase II in vitro.

K. Lee, K. Lee, Y. Kashiwada, 1993, Journal of pharmaceutical sciences.

New cytotoxic butanolides from Litsea acutivena.

K. Lee, C. Duh, I. Chen, 2001, Journal of natural products.

Design, synthesis and characterization of antimicrobial pseudopeptides corresponding to membrane-active peptide.

K. Lee, J. Oh, S. Hong, 1999, The journal of peptide research : official journal of the American Peptide Society.

Antitumor agents. Part 202: novel 2'-amino chalcones: design, synthesis and biological evaluation.

Yi Xia, K. Lee, K. Lee, 2000, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of 6 , 7 , 2 ′ , 3 ′ , 4 ′-Substituted-1 , 2 , 3 , 4-tetrahydro-2-phenyl-4-quinolones as a New Class of Antimitotic Antitumor Agents

S. Kuo, Yi Xia, K. Lee, 1998 .

Bioactive kaurane diterpenoids from Annona glabra.

F. Chang, J. Lin, K. Lee, 1998, Journal of natural products.

Antitumor agents XXIX: Effects of eupahyssopin on nucleic acid, protein, anaerobic, and aerobic metabolism of Ehrlich ascites tumor cells.

K. Lee, I. Hall, S. A. Eigebaly, 1978, Journal of pharmaceutical sciences.

Antitumor agents XXVII: Effects of helenalin on anaerobic and aerobic metabolism of Ehrlich ascites cells.

K. Lee, I. Hall, S. A. Eigebaly, 1978, Journal of pharmaceutical sciences.

Selective inactivation of rabbit reticulocyte initiation factor eIF-3 by helenalin.

S. Chaney, K. Lee, I. Hall, 1983, Biochimica et biophysica acta.

Anti-AIDS agents--XXVII. Synthesis and anti-HIV activity of betulinic acid and dihydrobetulinic acid derivatives.

K. Lee, Chin-Ho Chen, Y. Kashiwada, 1997, Bioorganic & medicinal chemistry.

Antitumor agents. 199. Three-dimensional quantitative structure-activity relationship study of the colchicine binding site ligands using comparative molecular field analysis.

A. Tropsha, A. Brossi, S. Kuo, 2000, Journal of medicinal chemistry.

Anti-AIDS agents. 37. Synthesis and structure-activity relationships of (3'R,4'R)-(+)-cis-khellactone derivatives as novel potent anti-HIV agents.

K. Lee, K. Lee, L. Cosentino, 1999, Journal of medicinal chemistry.

Antitumor agents--CLXXIII. Synthesis and evaluation of camptothecin-4 beta-amino-4'-O-demethyl epipodophyllotoxin conjugates as inhibitors of mammalian DNA topoisomerases and as cytotoxic agents.

Y. Cheng, K. Lee, H. Wang, 1997, Bioorganic & medicinal chemistry.

A Phytochemical Study of Borneo: Selected Plants from Sabah Lowland Forests

K. Lee, C. Chuah, S. Goh, 1997 .

Antitumor agents. XXXIV: Mechanism of action of bruceoside A and brusatol on nucleic acid metabolism of P-388 lymphocytic leukemia cells.

K. Lee, I. Hall, Y. Imakura, 1979, Journal of pharmaceutical sciences.

Anti-AIDS (acquired immune deficiency syndrome) agents. 17. New brominated hexahydroxybiphenyl derivatives as potent anti-HIV agents.

Y. Cheng, K. Lee, Y. Kashiwada, 1995, Journal of medicinal chemistry.

Antitumor agents. 207. Design, synthesis, and biological testing of 4beta-anilino-2-fluoro-4'-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents.

E. Huang, K. Lee, K. Bastow, 2001, Journal of medicinal chemistry.

Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.

M. Cosentino, F. Chang, K. Lee, 1996, Journal of natural products.

Anti-AIDS agents--XIX. Neotripterifordin, a novel anti-HIV principle from Tripterygium wilfordii: isolation and structural elucidation.

T. Nakano, R. Kilkuskie, K. Lee, 1995, Bioorganic & Medicinal Chemistry.

Anti-AIDS agents. 48.(1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis.

F. Chang, K. Lee, N. Kilgore, 2001, Journal of natural products.

Anti-AIDS agents, 18. Sodium and potassium salts of caffeic acid tetramers from Arnebia euchroma as anti-HIV agents.

K. Lee, K. Lee, T. Tanaka, 1995, Journal of natural products.

Anti-AIDS agents, 4. Tripterifordin, a novel anti-HIV principle from Tripterygium wilfordii: isolation and structural elucidation.

R. Kilkuskie, K. Lee, K. Lee, 1992, Journal of natural products.

Anti-AIDS agents, 2: Inhibitory effects of tannins on HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.

Y. Cheng, R. Kilkuskie, K. Lee, 1990, Journal of natural products.

Anti-AIDS agents, 1. Isolation and characterization of four new tetragalloylquinic acids as a new class of HIV reverse transcriptase inhibitors from tannic acid.

Y. Cheng, R. Kilkuskie, K. Lee, 1989, Journal of natural products.

Characterization of a novel inhibitor of human DNA polymerases: 3,4,5-tri-O-galloylquinic acid.

Y. Cheng, K. Lee, M. Fisher, 1989, Biochemical pharmacology.

Antitumor agents. 21. A proposed mechanism for inhibition of cancer growth by tenulin and helenalin and related cyclopentenones.

T. G. Waddell, K. Lee, I. Hall, 1977, Journal of medicinal chemistry.

Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents.

K. Lee, K. Lee, D. Li, 2000, Journal of natural products.

Sesquiterpenoid lactones of Artemisia. Constituents of Artemisia cana ssp. Cana. the structure of Canin

K. Lee, T. A. Geissman, R. F. Simpson, 1969 .

Synthesis and anticancer evaluation of certain gamma-aryloxymethyl-alpha-methylene-gamma-phenyl-gamma-butyrolactones.

C. Tzeng, K. Lee, S. Liou, 1998, Bioorganic & medicinal chemistry letters.

Antitumor agents. 89. Psychorubrin, a new cytotoxic naphthoquinone from Psychotria rubra and its structure-activity relationships.

K. Lee, T. Hayashi, F. Smith, 1987, Journal of medicinal chemistry.

Antitumor 2,3-dihydro-2-(aryl)-4(1H)-quinazolinone derivatives. Interactions with tubulin.

K. Paull, J. Plowman, K. Lee, 1996, Biochemical pharmacology.

6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

S. Kuo, Li‐Jiau Huang, M. Hour, 2000, Journal of medicinal chemistry.

Anti-AIDS agents. 42. Synthesis and anti-HIV activity of disubstituted (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone analogues.

A. McPhail, K. Lee, L. Cosentino, 2001, Journal of medicinal chemistry.

Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents.

A. Mauger, K. Lee, E. Hamel, 2001, Journal of medicinal chemistry.

Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.

M. Itoigawa, K. Lee, K. Lee, 2000, Journal of natural products.

Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

S. Kuo, A. Mauger, K. Lee, 1999, Journal of medicinal chemistry.

Chemical constituents of Prangos tschiniganica; structure elucidation and absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity.

K. Lee, Michiho Ito, Y. Takeda, 2001, Chemical & pharmaceutical bulletin.

Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents.

S. Kuo, C. Teng, M. Hour, 2001, Bioorganic & medicinal chemistry letters.

Anti-AIDS agents. 31. Synthesis and anti-HIV activity of 4-substituted 3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) thiolactone analogs.

K. Lee, L. Cosentino, Z. Y. Yang, 1998, Bioorganic & medicinal chemistry letters.

Synthesis and antiplatelet, antiinflammatory, and antiallergic activities of substituted 3-chloro-5,8-dimethoxy-1,4-naphthoquinone and related compounds.

S. Kuo, C. Teng, K. Lee, 1998, Bioorganic & medicinal chemistry.

Synthesis and antiplatelet, antiinflammatory and antiallergic activities of 2,3-disubstituted 1,4-naphthoquinones.

S. Kuo, C. Teng, K. Lee, 1996, Chemical & pharmaceutical bulletin.

Anti-AIDS agents. 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives.

M. Cosentino, K. Lee, K. Lee, 2001, Journal of natural products.

Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents.

S. Kuo, C. Teng, M. Hour, 2001, Bioorganic & medicinal chemistry letters.

Antitumor agents. 100. Inhibition of human DNA topoisomerase II by cytotoxic ether and ester derivatives of podophyllotoxin and alpha-peltatin.

Y. Cheng, K. Lee, M. Haruna, 1989, Journal of medicinal chemistry.

Recent advances in the discovery and development of quinolones and analogs as antitumor agents.

K. Lee, S. Morris-Natschke, Z. Y. Yang, 1999, Current medicinal chemistry.

A novel anti-HBeAg homolignan, taiwanschirin D from Kadsura matsudai.

K. Lee, R. Huang, Y. Kuo, 2000, Chemical & pharmaceutical bulletin.

Simple isoquinoline and benzylisoquinoline alkaloids as potential antimicrobial, antimalarial, cytotoxic, and anti-HIV agents.

Y. Wataya, K. Lee, M. Kozuka, 2001, Bioorganic & medicinal chemistry.

Anti-AIDS agents. 33. Synthesis and anti-HIV activity of mono-methyl substituted 3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) analogues.

K. Lee, L. Cosentino, Y. Takeuchi, 1997, Bioorganic & medicinal chemistry letters.

Anti-AIDS agents part 41: synthesis and anti-HIV activity of 3',4'-di-o-(-)-camphanoyl-(+)-cis-khellactone (DCK) lactam analogues.

A. Brossi, K. Lee, L. Cosentino, 2000, Bioorganic & medicinal chemistry letters.

Anti-AIDS agents. 15. Synthesis and anti-HIV activity of dihydroseselins and related analogs.

A. McPhail, K. Lee, Li Huang, 1994, Journal of medicinal chemistry.

Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization.

S. Kuo, A. Mauger, K. Lee, 1997, Journal of medicinal chemistry.

Antitumor agents. 144. New gamma-lactone ring-modified arylamino etoposide analogs as inhibitors of human DNA topoisomerase II.

K. J. Lee, Y. Cheng, K. Lee, 1994, Journal of medicinal chemistry.

Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides.

M. Cosentino, K. Lee, Li Huang, 1994, Bioorganic & medicinal chemistry.

Synthesis and antiplatelet activity of phenyl quinolones.

S. Kuo, C. Teng, K. Lee, 1998, Bioorganic & medicinal chemistry.

Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

S. Kuo, D. Lednicer, K. Lee, 1994, Journal of medicinal chemistry.

X-ray crystal structure of acrovestone, a cytotoxic principle from Acronychia pedunculata.

A. McPhail, K. Lee, T. S. Wu, 1989, Journal of natural products.

Anticancer drug design based on plant-derived natural products.

K. Lee, K H Lee, 1999, Journal of biomedical science.

Antitumor agents, 81. Justicidin-A and diphyllin, two cytotoxic principles from Justicia procumbens.

K. Lee, N. Fukamiya, Kuo Hsiung Lee, 1986, Journal of natural products.

Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.

S. Cho, Y. Cheng, K. Lee, 1999, Journal of medicinal chemistry.

Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. I. The producing organism, fermentation, isolation and biological properties.

K. Lee, R. Wu, T. Yokoi, 1988, The Journal of antibiotics.

Asymmetric solid-phase synthesis of (3'R,4'R)-di-O-cis-acyl 3-carboxyl khellactones.

A. Brossi, K. Lee, Z. Y. Yang, 1999, Organic letters.

New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C.

W. Janzen, K. Lee, Y. Kashiwada, 1994, Journal of medicinal chemistry.

Anti-AIDS agents. Part 47: Synthesis and anti-HIV activity of 3-substituted 3',4'-Di-O-(S)-camphanoyl-(3'R,4'R)-(+)-cis-khellactone derivatives.

K. Lee, N. Kilgore, G. Allaway, 2001, Bioorganic & medicinal chemistry letters.

Antitumor agents. 31. Helenalin sym-dimethylethylenediamine reaction products and related derivatives.

K. Lee, I. Hall, T. Ibuka, 1978, Journal of medicinal chemistry.

Antitumor agents. 25. Synthesis and antitumor activity of uracil and thymine alpha-methylene-gamma-lactones and related derivatives.

K. Lee, I. Hall, Y. S. Wu, 1977, Journal of medicinal chemistry.

The crystal structure and cytotoxicity of goniodiol-7-monoacetate from Goniothalamus amuyon.

F. Chang, A. McPhail, K. Lee, 1991, Journal of natural products.

Antitumor agents. 120. New 4-substituted benzylamine and benzyl ether derivatives of 4'-O-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.

Y. Cheng, K. Lee, J. Chang, 1991, Journal of medicinal chemistry.

Effect of 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin on human DNA topoisomerase II, tubulin polymerization, KB cells, and their resistant variants.

Y. Cheng, K. Lee, J. Chang, 1991, Cancer research.

Podophyllotoxin analogs: effects on DNA topoisomerase II, tubulin polymerization, human tumor KB cells, and their VP-16-resistant variants.

Y. Cheng, K. Lee, M. Haruna, 1989, Molecular pharmacology.

Antitumor agents 201. Cytotoxicity of harmine and beta-carboline analogs.

K. Lee, J. Ishida, H. Wang, 1999, Bioorganic & medicinal chemistry letters.

Antitumor agents 187: synthesis and cytotoxicity of substituted 8,8-dimethyl-2H,8H-pyrano[6,5-h]quinoline-2-one and related compounds.

K. Lee, K. Bastow, Z. Y. Yang, 1999, Bioorganic & medicinal chemistry letters.

Synthesis and antiplatelet, antiinflammatory, and antiallergic activities of 2-substituted 3-chloro-1,4-naphthoquinone derivatives.

S. Kuo, Li‐Jiau Huang, C. Teng, 1997, Bioorganic & medicinal chemistry.

Antitumor agents. 86. Synthesis and cytotoxicity of alpha-methylene-gamma-lactone-bearing purines.

K. Lee, V. Amarnath, I. Hall, 1987, Journal of medicinal chemistry.

Cytotoxicity of sesquiterpene lactones.

C. Piantadosi, E. Huang, K. Lee, 1971, Cancer research.

The discovery, characterization and crystallographically determined binding mode of an FMOC-containing inhibitor of HIV-1 protease.

R. Stroud, J. Alvarez, P. Ortiz de Montellano, 1997, Bioorganic & medicinal chemistry.

Antitumor agents 32. Synthesis and antitumor activity of cyclopentenone derivatives related to helenalin.

K. Lee, I. Hall, E. Mar, 1978, Journal of medicinal chemistry.

Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis.

A. McPhail, K. Lee, R. Wu, 1988, The Journal of antibiotics.

Recent progress in the development of tubulin inhibitors as antimitotic antitumor agents.

K. Lee, K. Lee, S. Morris-Natschke, 1970, Current pharmaceutical design.

Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents.

A. Brossi, A. McPhail, K. Lee, 1997, Journal of medicinal chemistry.

Antitumor agents--CLXXV. Anti-tubulin action of (+)-thiocolchicine prepared by partial synthesis.

A. Brossi, K. Lee, E. Hamel, 1997, Bioorganic & medicinal chemistry.

Sesquiterpene lactones of artemisia: Artemorin and dehydroartemorin (anhydroverlotorin)

K. Lee, T. A. Geissman, 1971 .

Anti-HIV agents 45(1) and antitumor agents 205.(2) two new sesquiterpenes, leitneridanins A and B, and the cytotoxic and anti-HIV principles from Leitneria floridana.

M. Cosentino, F. Chang, A. McPhail, 2000, Journal of natural products.

Recent advances in the discovery and development of flavonoids and their analogues as antitumor and anti-HIV agents.

Yi Xia, K. Lee, K. Lee, 1998, Advances in experimental medicine and biology.

Antimalarial agents. III. Mechanism of action of artesunate against Plasmodium berghei infection.

K. Lee, I. Hall, C. B. Oswald, 1987, Chemical & pharmaceutical bulletin.

The effects of genkwadaphnin and gnidilatidin on the growth of P-388, L-1210 leukemia and KB carcinoma cells in vitro.

K. Lee, I. Hall, C. B. Oswald, 1986, European journal of cancer & clinical oncology.

Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia tumor cells by helenalin and bis(helenalinyl)malonate in vivo.

S. Chaney, K. Lee, A. Grippo, 1988, Journal of pharmaceutical sciences.

Antitumor agents LXIII: the effects of microlenin on nucleic acid and protein syntheses of Ehrlich ascites cells.

K. Lee, I. Hall, Y. Imakura, 1983, Journal of pharmaceutical sciences.

Antitumor agents LIII: The effects of daphnoretin on nucleic acid and protein synthesis of Ehrlich ascites tumor cells.

K. Lee, K. Tagahara, I. Hall, 1982, Journal of pharmaceutical sciences.

Antitumor agents LII: The effects of molephantinin on nucleic acid and protein synthesis of Ehrlich ascites cells.

K. Lee, I. Hall, Y. Liou, 1982, Journal of pharmaceutical sciences.

Antitumor agents XLI: Effects of eupaformosanin on nucleic acid, protein, and anaerobic and aerobic glycolytic metabolism of Ehrlich ascites cells.

K. Lee, I. Hall, T. Kimura, 1980, Journal of pharmaceutical sciences.

Unique biochemical, cytotoxic, and antitumor activity of camptothecin and 4beta-amino-4'-O-demethylepipodophyllotoxin conjugates.

Y. Cheng, K. Lee, J. Chang, 2000, Biochemical pharmacology.

Antiproliferative actions of 7-substituted 1,3-dihydroxyacridones; possible involvement of DNA topoisomerase II and protein kinase C as biochemical targets.

M. Itoigawa, K. Lee, Y. Kashiwada, 1994, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of tetrademethyl isocolchicine derivatives as inhibitors of DNA topoisomerase action in vitro.

K. Lee, H. Tatematsu, K. Bastow, 1993, Bioorganic & medicinal chemistry.

Antitumor agents LV: Effects of genkwadaphnin and yuanhuacine on nucleic acid synthesis of P-388 lymphocytic leukemia cells.

R. Kasai, K. Lee, K. Tagahara, 1982, Journal of pharmaceutical sciences.

Antitumor agents XLVII: The effects of bisbrusatolyl malonate on P-388 lymphocytic leukemia cell metabolism.

S. Chaney, K. Lee, I. Hall, 1982, Journal of pharmaceutical sciences.

Anti-inflammatory activity of sesquiterpene lactones and related compounds.

T. G. Waddell, K. Lee, I. Hall, 1979, Journal of pharmaceutical sciences.

Antitumor agents 68: effects of a series of helenalin derivatives on P-388 lymphocytic leukemia nucleic acid and protein synthesis.

S. Chaney, K. Lee, I. Hall, 1985, Journal of pharmaceutical sciences.

Phenolic Constituents from the Flowers of Synurus excelsus

K. Lee, M. C. Yang, I. K. Lee, 2007 .

Antitumor agents, 116. Cytotoxic triterpenes from Maytenus diversifolia.

R. Kasai, K. Lee, S. Hirono, 1990, Journal of natural products.

Anti-AIDS agents, 21. Triterpenoid saponins as anti-HIV principles from fruits of Gleditsia japonica and Gymnocladus chinensis, and a structure-activity correlation.

K. Lee, T. Konoshima, Y. Kashiwada, 1995, Journal of natural products.

Antitumor agents, 119. Kansuiphorins A and B, two novel antileukemic diterpene esters from Euphorbia kansui.

T. Nakano, K. Lee, M. Haruna, 1991, Journal of natural products.

Cytotoxic pheophorbide-related compounds from Clerodendrum calamitosum and C. cyrtophyllum.

K. Lee, H. Wang, K. Bastow, 2001, Journal of natural products.

New constituents and antiplatelet aggregation and anti-HIV principles of Artemisia capillaris.

C. Teng, K. Lee, K. Lee, 2001, Bioorganic & medicinal chemistry.

Antitumor agents, 110. Bryophyllin B, a novel potent cytotoxic bufadienolide from Bryophyllum pinnatum.

K. Lee, M. Haruna, T. Yamagishi, 1989, Journal of natural products.

Antihyperlipidemic activity of sesquiterpene lactones and related compounds.

T. G. Waddell, K. Lee, I. Hall, 1980, Journal of pharmaceutical sciences.

Antitumor agents, 82. Cytotoxic sapogenols from Aesculus hippocastanum.

K. Lee, T. Konoshima, 1986, Journal of natural products.

Antimalarial agents, 2. Artesunate, an inhibitor of cytochrome oxidase activity in Plasmodium berghei.

K. Lee, Y. Zhao, W. K. Hanton, 1986, Journal of natural products.

Antitumor agents, 85. Cicutoxin, an antileukemic principle from Cicuta maculata, and the cytotoxicity of the related derivatives.

K. Lee, T. Konoshima, 1986, Journal of natural products.

Sesquiterpene lactones of Artemisia verlotorum

K. Lee, T. A. Geissman, 1971 .

Sesquiterpene lactones of Artemisia: New guaianolides from fall growth of A. Douglasiana☆

K. Lee, T. A. Geissman, S. Matsueda, 1971 .

Sesquiterpene lactones of artemisia species: artefransin from a. franserioides

K. Lee, T. A. Geissman, 1971 .

Sesquiterpene lactones of artemisia. ridentin

K. Lee, T. A. Geissman, R. F. Simpson, 1969 .

Renal, hepatic, cardiac and thymic acute toxicity afforded by bis(helenalinyl)malonate in BDF1 mice.

S. Chaney, K. Lee, A. Grippo, 1990, Toxicology.

Antitumor agents. 44. Bis(helenalinyl) esters and related derivatives as novel potent antileukemic agents.

K. Lee, H. Kim, I. Hall, 1981, Journal of medicinal chemistry.

Antitumor agents XXXVI: Structural elucidation of sesquiterpene lactones microhelenins-A, B, and C, microlenin acetate, and plenolin from Helenium microcephalum.

M. Itoigawa, K. Lee, I. Hall, 1980, Journal of pharmaceutical sciences.

Antitumor agents XXVIII: Structural elucidation of the novel antitumor sesquiterpene lactone, microlenin, from Helenium microcephalum.

K. Lee, I. Hall, Y. Imakura, 1978, Journal of pharmaceutical sciences.

Antitumor agents LIV: The effects of daphnoretin on in vitro protein synthesis of Ehrlich ascites carcinoma cells and other tissues.

K. Lee, I. Hall, Y. Liou, 1982, Journal of pharmaceutical sciences.

Antitumor agents. 49 tricin, kaempferol-3-O-beta-D-glucopyranoside and (+)-nortrachelogenin, antileukemic principles from Wikstroemia indica.

K. Lee, K. Tagahara, M. Haruna, 1981, Journal of natural products.

Activities of novel nonglycosidic epipodophyllotoxins in etoposide-sensitive and -resistant variants of human KB cells, P-388 cells, and in vivo multidrug-resistant murine leukemia cells.

Y. Cheng, K. Lee, H. X. Chen, 1996, Molecular pharmacology.

Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors.

A. Brossi, K. Lee, E. Hamel, 1998, Bioorganic & medicinal chemistry.

Antitumor agents. 78. Inhibition of human DNA topoisomerase II by podophyllotoxin and alpha-peltatin analogues.

Y. Cheng, K. Lee, H. Irie, 1986, Journal of medicinal chemistry.

Antitumor agents LIX: effects of quassinoids on protein synthesis of a number of murine tumors and normal cells.

S. Chaney, K. Lee, I. Hall, 1983, Journal of pharmaceutical sciences.

Structure-activity relationships for binding and inactivation of rabbit reticulocyte ribosomes by quassinoid antineoplastic agents.

S. Wyrick, S. Chaney, K. Lee, 1983, European journal of biochemistry.

Mechanism of eukaryotic protein synthesis inhibition by brusatol.

S. Chaney, K. Lee, E. A. Stafford, 1981, Biochimica et biophysica acta.

Antitumor agents. XXXV: Effects of brusatol, bruceoside A, and bruceantin on P-388 lymphocytic leukemia cell respiration.

K. Lee, I. Hall, Y. Imakura, 1979, Journal of pharmaceutical sciences.

Inhibition of inosine monophosphate dehydrogenase by sesquiterpene lactones.

S. Chaney, K. Lee, I. Hall, 1987, Biochimica et biophysica acta.

Inhibition of protein synthesis initiation factors by naturally occurring sulfhydryl reactive reagents.

S. Chaney, K. Lee, I. Hall, 1984, Current topics in cellular regulation.

Investigation of sesquiterpene lactones as protein synthesis inhibitors of P-388 lymphocytic leukemia cells.

S. Chaney, K. Lee, I. Hall, 1983, Biochimica et biophysica acta.

Antitumor agents XXXVIII: Isolation and structural elucidation of novel germacranolides and triterpenes from Elephantopus mollis.

K. Lee, M. Kozuka, I. Hall, 1980, Journal of pharmaceutical sciences.

Antitumor agents. 4. Cytotoxicity and in vitro activity of helenalin esters and related derivatives.

C. Piantadosi, E. Huang, K. Lee, 1973, Journal of medicinal chemistry.

Antitumor agents. 3. Synthesis and cytotoxic activity of helenalin amine adducts and related derivatives.

K. Lee, H. Furukawa, 1972, Journal of medicinal chemistry.

Antitumor agents LVI: the protein synthesis inhibition by genkwadaphnin and yuanhuacine of P-388 lymphocytic leukemia cells.

K. Lee, I. Hall, Y. Liou, 1982, Journal of pharmaceutical sciences.

Antitumor agents XXIII: Helenalin, and antitumor principle from Anaphalis morrisonicola HAY.

K. Lee, M. Haruna, I. Hall, 1977, Journal of pharmaceutical sciences.

Indirect inactivation of rabbit reticulocyte initiation factor eIF-2 by helenalin and bis(helenalinyl) malonate.

S. Chaney, K. Lee, I. Hall, 1984, Biochemistry.

Anti-AIDS agents 38. Anti-HIV activity of 3-O-acyl ursolic acid derivatives.

K. Lee, K. Lee, Y. Kashiwada, 2000, Journal of natural products.

Prevention of binding of rgp120 by anti-HIV active tannins.

P. S. Pine, Y. Cheng, K. Lee, 1992, Biochemical pharmacology.

Two new macrolide sesquiterpene pyridine alkaloids from Maytenus emarginata: emarginatine G and the cytotoxic emarginatine F.

Y. Kuo, K. Lee, K. Chen, 1994, Journal of natural products.

The comparison of characteristics between membrane-active antifungal peptide and its pseudopeptides.

K. Lee, J. Oh, S. Hong, 1999, Bioorganic & medicinal chemistry.

Synthesis and anti-HIV activity of oleanolic acid derivatives.

K. Lee, L. Cosentino, H. Wang, 2001, Bioorganic & medicinal chemistry letters.

Phenolic Constituents of Althaea rosea Canival.

D. Kim, K. Lee, M. C. Yang, 2007 .

Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa.

K. Lee, T. Konoshima, M. Kozuka, 1993, Journal of natural products.

Anti-AIDS agents, 9. Suberosol, a new C31 lanostane-type triterpene and anti-HIV principle from Polyalthia suberosa.

K. Lee, K. Lee, Y. Kashiwada, 1993, Journal of natural products.

Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives.

M. Iinuma, K. Lee, M. Ohyama, 1999, Bioorganic & medicinal chemistry letters.

Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues.

Ke Chen, K. Lee, Y. Kashiwada, 1997, Bioorganic & medicinal chemistry.

Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior.

Ke Chen, K. Lee, L. Cosentino, 1996, Journal of natural products.

Anti-tuberculosis activity of quassinoids.

K. Lee, K. Tagahara, N. Fukamiya, 1997, Chemical & pharmaceutical bulletin.

Quassinoids as inhibitors of Epstein-Barr virus early antigen activation.

K. Lee, H. Nishino, K. Tagahara, 1997, Cancer letters.

In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates.

T. Park, H. Yoo, K. Lee, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Dantaxusins A and B, two new taxoids from Taxus yunnanensis.

K. Lee, K. Tagahara, T. Nehira, 2001, Journal of natural products.

Antitumor agents--CLXVII. Synthesis and structure-activity correlations of the cytotoxic anthraquinone 1,4-bis-(2,3-epoxypropylamino)-9,10-anthracenedione, and of related compounds.

M. G. Johnson, A. Mauger, K. Lee, 1997, Bioorganic & medicinal chemistry.

Antitumor agents 50. 1 Morindaparvin-A, a new antileukemic anthraquinone, and alizarin-1-methyl ether from Morinda parvifolia, and the antileukemic activity of the related derivatives.

K. Lee, I. Hall, T. Shingu, 1982, Journal of natural products.

Antitumor agents LXII: synthesis and biological evaluation of podophyllotoxin esters and related derivatives.

K. Lee, I. Hall, R. Levy, 1983, Journal of pharmaceutical sciences.

Anti-HIV and cytotoxic activities of Ru(II)/Ru(III) polypyridyl complexes containing 2,6-(2'-benzimidazolyl)-pyridine/chalcone as co-ligand.

K. Lee, N. Kilgore, H. Itokawa, 2001, Bioorganic & medicinal chemistry.

Anti-AIDS agents. 32. Synthesis and anti-HIV activity of betulin derivatives.

K. Lee, K. Lee, L. Cosentino, 1998, Bioorganic & medicinal chemistry letters.

The interaction between halogenated anaesthetics and bacteriorhodopsin in purple membranes as examined by intrinsic ultraviolet fluorescence.

K. Lee, F. Boucher, A. Mcintosh, 1991, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Characterization of the unique function of a reduced amide bond in a cytolytic peptide that acts on phospholipid membranes.

K. Lee, J. Oh, 2000, The Biochemical journal.

Design and synthesis of novel antimicrobial pseudopeptides with selective membrane-perturbation activity.

K. Lee, J. Oh, 2000, Bioorganic & medicinal chemistry.

Picrasinoside H, a new quassinoid glucoside, and related compounds from the stem wood of Picrasma ailanthoides.

K. Lee, K. Tagahara, T. Fujita, 1991, Journal of natural products.

Conjugation of drug to poly(D,L-lactic-co-glycolic acid) for controlled release from biodegradable microspheres.

Y. Nam, K. Lee, J. Oh, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Novel anti-HIV lancilactone C and related triterpenes from Kadsura lancilimba.

K. Lee, K. Lee, L. Cosentino, 1999, Journal of natural products.

Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones.

K. Lee, L. Cosentino, H. Wang, 1996, Journal of medicinal chemistry.

Antitumor agents, 135. Structure and stereochemistry of polacandrin, a new cytotoxic triterpene from Polanisia dodecandra.

A. McPhail, K. Lee, T. Fujioka, 1992, Journal of natural products.

Synthesis and anti-HIV activity of 3-alkylamido-3-deoxy-betulinic acid derivatives.

K. Lee, S. Morris-Natschke, Y. Kashiwada, 2000, Chemical & pharmaceutical bulletin.

Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine

K. Lee, K. Lee, 2000, Public Health Nutrition.

Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

S. Kuo, A. Mauger, K. Lee, 1997, Journal of medicinal chemistry.

Cytotoxity of non-alkaloidal taxane diterpenes from Taxus chinensis against a paclitaxel-resistant cell line.

K. Lee, K. Tagahara, T. Nehira, 2000, Cancer letters.

A new taxoid, 19-acetoxytaxagifine, from Taxus chinensis.

K. Lee, K. Tagahara, D. C. Zhang, 1999, Journal of Natural Products.

Structures and stereochemistry of pseudolarolides K and L, novel triterpene dilactones from pseudolarix kaempferi.

K. Lee, Z. Li, K. Chen, 1999, Journal of Asian natural products research.

Structure and stereochemistry of pseudolarolide J, a novel nortriterpene lactone from Pseudolarix kaempferi.

Y. L. Zhang, A. McPhail, K. Lee, 1996, Journal of natural products.

The isolation and structural elucidation of four novel triterpene lactones, pseudolarolides A, B, C, and D, from Pseudolarix kaempferi.

K. Lee, Z. Li, K. Chen, 1993, Journal of natural products.

Inhibitory effects of quassinoids on Epstein-Barr virus activation.

K. Lee, H. Nishino, K. Tagahara, 1995, Cancer letters.

Reversibility of protein synthesis inhibition by quassinoid antineoplastic agents in a rabbit reticulocyte system.

S. Chaney, K. Lee, I. Hall, 1984, Biochemical pharmacology.

Antitumor agents XLVIII: Structure-activity relationships of quassinoids as in vitro protein synthesis inhibitors of P-388 lymphocytic leukemia tumor cell metabolism.

S. Chaney, K. Lee, I. Hall, 1982, Journal of pharmaceutical sciences.

Antitumor agents XLV: Bisbrusatolyl and brusatolyl esters and related compounds as novel potent antileukemic agents.

K. Lee, I. Hall, D. Brent, 1982, Journal of pharmaceutical sciences.

Substituted 7H-pyrido[4,3-c]carbazoles with potent anti-HIV activity.

M. Itoigawa, K. Lee, L. Cosentino, 1999, Bioorganic & medicinal chemistry letters.

Structure and stereochemistry of bryophyllin-A, a novel potent cytotoxic bufadienolide orthoacetate from Bryophyllum pinnatum.

A. McPhail, K. Lee, T. Yamagishi, 1988, Chemical & pharmaceutical bulletin.

Synthesis and cytotoxicity of acetyl-4H,9H-naphtho[2,3-b]thiophene-4,9-diones.

S. Kuo, A. Mauger, A. McPhail, 1998, Bioorganic & medicinal chemistry letters.

Site-specific DNA cleavage by Cu(II) complexes of podophyllotoxin derivatives.

K. Lee, R. Tawa, Y. Imakura, 1994, Biochemical pharmacology.

Antitumor agents. 113. New 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II.

D. Schnur, Y. Cheng, J. P. Bowen, 1990, Journal of medicinal chemistry.

Antitumor agents. 111. New 4-hydroxylated and 4-halogenated anilino derivatives of 4'-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.

Y. Cheng, K. Lee, J. Chang, 1990, Journal of medicinal chemistry.

Synthesis and cytotoxicity of methyl-4,8-dihydrobenzo[1,2-b:5,4-b']dithiophene-4,8-dione derivatives.

S. Kuo, A. Mauger, K. Lee, 1999, Bioorganic & medicinal chemistry.

Antimalarial agents, 4. Synthesis of a brusatol analog and biological activity of brusatol-related compounds.

K. Lee, Y. Imakura, S. Tani, 1987, Journal of natural products.

Synthesis of novel water-soluble 7-(aminoacylhydrazono)-formyl camptothecins with potent inhibition of DNA topoisomerase I.

K. Lee, H. Wang, S. Liu, 1994, Bioorganic & medicinal chemistry.

Inhibition of DNA topoisomerases by sanguiin H-6, a cytotoxic dimeric ellagitannin from Sanguisorba officinalis.

K. Lee, T. Tanaka, Y. Kashiwada, 1993, Planta medica.

Antitumor agents, 107. New cytotoxic 4-alkylamino analogues of 4'-demethyl-epipodophyllotoxin as inhibitors of human DNA topoisomerase II.

Y. Cheng, K. Lee, M. Haruna, 1989, Journal of natural products.

Novel anti-prostate cancer curcumin analogues that enhance androgen receptor degradation activity.

K. Lee, Q. Shi, C. Shih, 2009, Anti-cancer agents in medicinal chemistry.

Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.

K. Lee, Chin-Ho Chen, K. Lee, 1998, Journal of medicinal chemistry.

Cytotoxicity of isoquinoline alkaloids and their N-oxides.

K. Lee, Y. C. Wu, J. Chang, 1989, Planta medica.

3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents.

K. Lee, Y. Kashiwada, L. Cosentino, 2001, Bioorganic & medicinal chemistry letters.

Structure-activity analysis of brevinin 1E amide, an antimicrobial peptide from Rana esculenta.

K. Lee, S. Hong, M. Kwon, 1998, Biochimica et biophysica acta.

Antitumor agents, 112. Emarginatine B, a novel potent cytotoxic sesquiterpene pyridine alkaloid from Maytenus emarginata.

Y. Kuo, K. Lee, M. Haruna, 1990, Journal of natural products.

Celahinine A, a new sesquiterpene pyridine alkaloid from Celastrus hindsii.

Y. Kuo, K. Lee, L. M. Kuo, 1995, Journal of natural products.

Antitumor agents. 180. Chemical Studies and cytotoxic evaluation of cumingianosides and cumindysoside A, antileukemic triterpene glucosides with a 14,18-cycloapotirucallane skeleton.

K. Lee, T. Fujioka, Y. Kashiwada, 1997, Journal of natural products.

Antitumor agents. 169 Dysoxylum cumingianum. V. Cumingianosides P and Q, new cytotoxic triterpene glucosides with an apotirucallane-type skeleton from Dysoxylum cumingianum.

K. Lee, T. Fujioka, Y. Kashiwada, 1997, Chemical & pharmaceutical bulletin.

Antitumor agents. 168. Dysoxylum cumingianum. IV. The structures of cumingianosides G-O, new triterpene glucosides with a 14,18-cycloapotirucallane-type skeleton from Dysoxylum cumingianum, and their cytotoxicity against human cancer cell lines.

K. Lee, T. Fujioka, Y. Kashiwada, 1997, Chemical & pharmaceutical bulletin.

Antitumor agents, 157. Absolute structures of cumingianosides A-F, antileukemic triterpene glucosides, and structures of the hydrolysates of cumingianoside A.

K. Lee, T. Fujioka, Y. Kashiwada, 1995, Journal of natural products.

Antitumor agents. 163. Three-dimensional quantitative structure-activity relationship study of 4'-O-demethylepipodophyllotoxin analogs using the modified CoMFA/q2-GRS approach.

S. Cho, Y. Cheng, A. Tropsha, 1996, Journal of medicinal chemistry.

Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.

S. Cho, Y. Cheng, K. Lee, 1996, Journal of medicinal chemistry.

Antitumor agents. 123. Synthesis and human DNA topoisomerase II inhibitory activity of 2'-chloro derivatives of etoposide and 4 beta-(arylamino)-4'-O-demethylpodophyllotoxins.

Y. Cheng, K. Lee, Z. Wang, 1992, Journal of medicinal chemistry.

Metal- and photo-induced cleavage of DNA by podophyllotoxin, etoposide, and their related compounds.

H. Sakurai, K. Lee, Y. Imakura, 1991, Molecular pharmacology.

Antitumor agents, 127. Bruceoside C, a new cytotoxic quassinoid glucoside, and related compounds from Brucea javanica.

K. Lee, K. Tagahara, N. Fukamiya, 1992, Journal of natural products.

Antitumor agents. 190. Absolute stereochemistry of the cytotoxic germacranolides, tomenphantins A and B, from Elephantopus tomentosus.

T. Nakano, A. McPhail, K. Lee, 1999, Journal of Natural Products.

Antitumor agents, 71. Nudaphantin, a new cytotoxic germacranolide, and elephantopin from Elephantopus nudatus.

K. Lee, M. Haruna, G. Rice, 1985, Journal of natural products.

Antitumor agents. 155. Synthesis and biological evaluation of 3',6,7-substituted 2-phenyl-4-quinolones as antimicrotubule agents.

S. Kuo, A. Mauger, K. Lee, 1994, Journal of medicinal chemistry.

Antitumor agents, 65. Brusatol and cleomiscosin-A, antileukemic principles from Brucea javanica.

N. Hayashi, K. Lee, M. Okano, 1984, Journal of Natural Products.

Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica.

K. Lee, K. Tagahara, S. Ohnishi, 1995, Journal of natural products.

Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. III. Structure-activity relationships.

K. Lee, R. Wu, T. Yokoi, 1988, The Journal of antibiotics.

Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds.

K. Lee, E. Hamel, C. Lin, 1993, Journal of medicinal chemistry.

Antitumor agents, 99. Synthetic ring C aromatized podophyllotoxin analogues as potential inhibitors of human DNA topoisomerase II.

K. Lee, Y. Imakura, S. Beers, 1988, Journal of natural products.

Constituents of rosaceous plants. I. Structure of new triterpenoids from Cowania mexicana.

K. Lee, T. Konoshima, M. Kozuka, 1993, Chemical & pharmaceutical bulletin.

Anti-AIDS agents. Part 36: 17-carboxylated steroids as potential anti-HIV agents.

K. Lee, L. Cosentino, Z. Y. Yang, 1999, Bioorganic & medicinal chemistry.

Antimalarial agents. 1. alpha-Santonin-derived cyclic peroxide as potential antimalarial agent.

R. O. Pick, K. Lee, H. Kiyokawa, 1985, Journal of medicinal chemistry.

Structure-activity relationship study: short antimicrobial peptides.

K. Lee, J. Oh, S. Hong, 1999, The journal of peptide research : official journal of the American Peptide Society.

Synthesis of cytotoxic fluorinated quassinoids.

K. Lee, K. Tagahara, N. Fukamiya, 1997, Bioorganic & medicinal chemistry.

Structural and functional implications of a proline residue in the antimicrobial peptide gaegurin.

C. B. Park, Byong-Seok Choi, S. C. Kim, 1999, European journal of biochemistry.

Manuifolins D, E, and F: new isoflavonoids from Maackia tenuifolia.

K. Lee, D. Zhu, J. Zeng, 1997, Journal of natural products.

Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors.

A. Brossi, K. Lee, E. Hamel, 1998, Journal of medicinal chemistry.

Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica.

K. Negoro, A. McPhail, K. Lee, 1986, Journal of Natural Products.

Bruceanols D, E, and F three new cytotoxic quassinoids from Brucea antidysenterica.

K. Lee, K. Tagahara, N. Fukamiya, 1993, Journal of Natural Products.

Antitumor agents, 118. The isolation and characterization of bruceanic acid A, its methyl ester, and the new bruceanic acids B, C, and D, from Brucea antidysenterica.

K. Lee, K. Tagahara, J. Chang, 1990, Journal of Natural Products.

Antitumor agents, 104. Isolation of yadanziosides M and P from Brucea antidysenterica and identification of bruceantinoside B as a mixture of yadanzioside P and bruceantinoside C.

K. Lee, K. Tagahara, N. Fukamiya, 1989, Journal of Natural Products.

Antitumor agents, 93. Bruceanol C, a new cytotoxic quassinoid from Brucea antidysenterica.

K. Lee, K. Tagahara, N. Fukamiya, 1988, Journal of Natural Products.

Antitumor agents, 90. Bruceantinoside C, a new cytotoxic quassinoid glycoside from Brucea antidysenterica.

K. Lee, K. Tagahara, N. Fukamiya, 1987, Journal of Natural Products.

Antitumor agents, 74. Bruceanol-A and -B, two new antileukemic quassinoids from Brucea antidysenterica.

K. Lee, N. Fukamiya, M. Okano, 1985, Journal of Natural Products.

Antitumor agents. 39. Bruceantinoside-A and -B, novel antileukemic quassinoid glucosides from Brucea antidysenterica.

K. Lee, I. Hall, M. Okano, 1981, Journal of Natural Products.

Antitumor agents, 145. Cytotoxic asprellic acids A and C and asprellic acid B. new p-coumaroyl triterpenes, from Ilex asprella.

K. Lee, Y. Kashiwada, J. Chang, 1993, Journal of Natural Products.

Novel cytotoxic diterpenes from the stem of Dysoxylum kuskusense.

K. Lee, T. Fujioka, Y. Kashiwada, 1998, Bioorganic & medicinal chemistry letters.

Cytotoxic isoquinoline alkaloids from Xanthorhiza simplicissima.

K. Lee, Y. C. Wu, T. Yamagishi, 1989, Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences.

Synthesis and cytotoxicity of 2-acetyl-4,8-dihydrobenzodithiophene-4, 8-dione derivatives.

S. Kuo, A. Mauger, K. Lee, 1998, Journal of medicinal chemistry.

Synthesis and cytotoxicity of 1,2-disubstituted naphth[2,3-d]imidazole-4,9-diones and related compounds.

S. Kuo, D. Lednicer, K. Lee, 1996, Journal of medicinal chemistry.