L. Afzelius

发表

Predicting drug metabolism: a site of metabolism prediction tool applied to the cytochrome P450 2C9.

Gabriele Cruciani, Ismael Zamora, Lovisa Afzelius, 2003, Journal of medicinal chemistry.

Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676

C. Halldin, K. Varnäs, L. Farde, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Structural analysis of CYP2C9 and CYP2C5 and an evaluation of commonly used molecular modeling techniques.

C. Masimirembwa, T. Andersson, I. Zamora, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 311 Computational Modelling of Structures and Ligands of CYP2C9

L. Afzelius, 2004 .

Computational Modelling of Structures and Ligands of CYP 2 C 9 BY LOVISA AFZELIUS

L. Afzelius, 2004 .

DMD054932 441..447

L. Afzelius, G. Englund, J. Hoogstraate, 2014 .

A probabilistic pathway score (PROPS) for classification with applications to inflammatory bowel disease

Russ B. Altman, Lichy Han, Mateusz Maciejewski, 2017, Bioinform..

DMD054155 459..468

U. Fagerholm, L. Afzelius, J. Hoogstraate, 2014 .

Discriminant and quantitative PLS analysis of competitive CYP2C9 inhibitors versus non-inhibitors using alignment independent GRIND descriptors

Ismael Zamora, Anders Karlén, Collen M. Masimirembwa, 2002, J. Comput. Aided Mol. Des..

Studies of Swedish marine organisms. I. Screening of biological activity.

L. Bohlin, L. Afzelius, S. Ogren, 1983, Acta pharmaceutica Suecica.

Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis.

S. Snapper, A. Bousvaros, J. Korzenik, 2018, Inflammatory bowel diseases.

Mendelian Disease Associations Reveal Novel Insights into Inflammatory Bowel Disease

R. Altman, L. Afzelius, Lichy Han, 2018, Inflammatory bowel diseases.

Practical use of the regression offset approach for the prediction of in vivo intrinsic clearance from hepatocytes

Douglas Ferguson, Lovisa Afzelius, Brian Middleton, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model

Johan Lööf, Tommy B. Andersson, Lovisa Afzelius, 2014, Drug Metabolism and Disposition.

Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds

P. Prusis, L. Afzelius, C. Petersson, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

T. Andersson, L. Afzelius, J. Bylund, 2014, Drug Metabolism and Disposition.

Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition

T. Andersson, L. Afzelius, G. Englund, 2014, Drug Metabolism and Disposition.

Microsoft Word-46053227-file00

T. Andersson, L. Afzelius, G. Englund, 2014 .

State-of-the-art Tools for Computational Site of Metabolism Predictions: Comparative Analysis, Mechanistical Insights, and Future Applications

Lars Carlsson, Anders Broo, Ulrik Jurva, 2007, Drug metabolism reviews.

Distinct clinical phenotypes for Crohn’s disease derived from patient surveys

A. Auton, V. Vacic, R. Altman, 2021, BMC Gastroenterology.

Reduced vdW Radius Improves Site of Metabolism Predictions Using X‐Ray Structure of CYP2D6

Peteris Prusis, Lovisa Afzelius, P. Prusis, 2009 .

Structural analysis of CYP2C9 and CYP2C5 and an evaluation of commonly used molecular modeling techniques.

Anders Karlén, Flemming Steen Jørgensen, Florian Raubacher, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Competitive CYP2C9 inhibitors: enzyme inhibition studies, protein homology modeling, and three-dimensional quantitative structure-activity relationship analysis.

C. Masimirembwa, T. Andersson, I. Zamora, 2001, Molecular pharmacology.

Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors

Tommy B. Andersson, Lovisa Afzelius, T. Andersson, 2014, Drug Metabolism and Disposition.

Microsoft Word-9352040-file00

U. Fagerholm, L. Afzelius, J. Hoogstraate, 2014 .

Inhibitory Properties of Common Efflux Transporter Inhibitors

T. Andersson, L. Afzelius, G. Englund, 2014 .

The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

T. Andersson, L. Afzelius, J. Bylund, 2014, Drug Metabolism and Disposition.

COMPARISON OF METHODS FOR THE PREDICTION OF THE METABOLIC SITES FOR CYP3A4-MEDIATED METABOLIC REACTIONS

Diansong Zhou, Ismael Zamora, Tommy B Andersson, 2006, Drug Metabolism and Disposition.

Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis.

S. Snapper, A. Bousvaros, J. Korzenik, 2018, Inflammatory bowel diseases.