B. Becattini

发表

NMR-based techniques in the hit identification and optimisation processes

Dawoon Jung, Maurizio Pellecchia, Lutz Tautz, 2004, Expert opinion on therapeutic targets.

Efficient synthetic inhibitors of anthrax lethal factor.

Dawoon Jung, Maurizio Pellecchia, Alex Y Strongin, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Insulin signaling and glucose metabolism in different hepatoma cell lines deviate from hepatocyte physiology toward a convergent aberrant phenotype

B. Becattini, G. Solinas, A. Molinaro, 2020, Scientific Reports.

JNK1 ablation improves pancreatic β‐cell mass and function in db/db diabetic mice without affecting insulin sensitivity and adipose tissue inflammation

B. Becattini, A. Mazzoli, F. Theilig, 2020, FASEB bioAdvances.

JNK1 ablation in mice confers long‐term metabolic protection from diet‐induced obesity at the cost of moderate skin oxidative damage

M. Choo, A. Provenzani, B. Becattini, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance

J. Montani, M. Wymann, B. Thorens, 2011, Proceedings of the National Academy of Sciences.

Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS.

F. Bäckhed, A. Molinaro, B. Becattini, 2019, Cell metabolism.

PI3Kγ ablation does not promote diabetes in db/db mice, but improves insulin sensitivity and reduces pancreatic β‐cell apoptosis

B. Becattini, G. Solinas, F. Zani, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification of a new JNK inhibitor targeting the JNK-JIP interaction site

Maurizio Pellecchia, Giovanni Solinas, Michael Karin, 2008, Proceedings of the National Academy of Sciences.

PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity

M. Wymann, R. Marone, B. Becattini, 2017, Science Signaling.

Somatic ablation of IKKβ in liver and leukocytes is not tolerated in obese mice but hepatic IKKβ deletion improves fatty liver and insulin sensitivity

P. Jansson, B. Becattini, G. Solinas, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Boron: A key element in radical reactions

B. Becattini, P. Renaud, E. Scanlan, 2007 .

Yersinia Phosphatase Induces Mitochondrially Dependent Apoptosis of T Cells*

A. Alonso, T. Mustelin, G. Salvesen, 2005, Journal of Biological Chemistry.

Rational Design and Real Time , In-Cell Detection of the Proapoptotic Activity of a Novel Compound Targeting Bcl-XL trials

T. Kipps, John Calvin Reed, M. Pellecchia, 2004 .

Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

T. Kipps, John Calvin Reed, M. Pellecchia, 2004, Chemistry & biology.

PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and G L expression.

J. Montani, A. Provenzani, U. Albrecht, 2013, Molecular metabolism.

Carbohydrate-Based Peptido Mimetics. Synthesis of Two New Scaffolds for Combinatorial Libraries.

S. Menichetti, B. Becattini, A. Salvini, 2000 .

Thiophenol-Mediated 1,5-Hydrogen Atom Abstraction: Easy Access to Mono- and Bicyclic Compounds

F. Beaufils, B. Becattini, K. Schenk, 2005 .

Carbohydrate‐Based Peptido Mimetics. Synthesis of Two New Scaffolds for Combinatorial Libraries.

S. Menichetti, B. Becattini, A. Salvini, 2000 .

Hyperinsulinemia and insulin resistance in the obese may develop as part of a homeostatic response to elevated free fatty acids: A mechanistic case-control and a population-based cohort study

L. Lind, P. Jansson, S. Piazza, 2021, EBioMedicine.

Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia

N. Plesnila, Changlian Zhu, C. Culmsee, 2005, The Journal of Neuroscience.

JNK at the crossroad of obesity, insulin resistance, and cell stress response

B. Becattini, G. Solinas, 2016, Molecular metabolism.

Structure–activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid

Maurizio Pellecchia, Marilisa Leone, John C Reed, 2006, Proceedings of the National Academy of Sciences.

Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

Maurizio Pellecchia, Marilisa Leone, John C Reed, 2004, Chemistry & biology.

Bid-induced release of AIF from mitochondria causes immediate neuronal cell death

N. Plesnila, C. Culmsee, S. Duvezin-Caubet, 2008, Cell Death and Differentiation.

The role of PI3Kγ in metabolism and macrophage activation

B. Becattini, G. Solinas, 2017, Oncotarget.

Rational Design and Real Time, In-Cell Detection of the Proapoptotic Activity of a Novel Compound Targeting Bcl-XL

Maurizio Pellecchia, Marilisa Leone, Thomas J. Kipps, 2004 .

Insulin signaling and glucose metabolism in different hepatoma cell lines deviate from hepatocyte physiology toward a convergent aberrant phenotype

B. Becattini, G. Solinas, A. Molinaro, 2020, Scientific Reports.

PSD3 downregulation confers protection against fatty liver disease

C. Datz, F. Pattou, A. Andréasson, 2022, Nature Metabolism.

SAR by ILOEs: an NMR-based approach to reverse chemical genetics.

Maurizio Pellecchia, M. Pellecchia, B. Becattini, 2006, Chemistry.

Adipocyte PI3K links adipostasis with insulin secretion through an adipoincretin effect

J. Borén, B. Becattini, Marcus Henricsson, 2023, bioRxiv.

PI3Kγ promotes obesity-associated hepatocellular carcinoma by regulating metabolism and inflammation

B. Becattini, G. Solinas, F. Zani, 2021, JHEP reports : innovation in hepatology.