H. Rokos

发表

Computer simulation of native epidermal enzyme structures in the presence and absence of hydrogen peroxide (H2O2): potential and pitfalls.

N. J. Gibbons, J. Wood, H. Rokos, 2006, The Journal of investigative dermatology.

Affinity labeling of rat liver and kidney type I 5'-deiodinase. Identification of the 27-kDa substrate binding subunit.

J. Köhrle, U. Rasmussen, H. Rokos, 1990, The Journal of biological chemistry.

Antiviral and hemolytic activities of surfactin isoforms and their methyl ester derivatives.

M. Ozel, G. Pauli, H. Rokos, 1999, The Journal of antibiotics.

Serial Transplants of DMBA-Induced Mammary Tumors in Fischer Rats as a Model System for Human Breast Cancer

D. Mecke, H. Rokos, A. Stieglitz, 1999, Oncology.

Rat liver iodothyronine monodeiodinase. Evaluation of the iodothyronine ligand-binding site.

V. Cody, H. Rokos, R. Hesch, 1986, The Journal of biological chemistry.

Cholesterol regulates melanogenesis in human epidermal melanocytes and melanoma cells

J. Wood, H. Rokos, K. Schallreuter, 2009, Experimental dermatology.

Serum biopterin — a novel marker for immune activation during pre-diabetes in the BB rat

H. Rokos, A. Davies, A. Bone, 1994, Diabetologia.

Structural requirements of iodothyronines for the rapid inactivation and internalization of type II iodothyronine 5'-deiodinase in glial cells.

M. Safran, H. Rokos, J. L. Leonard, 1993, The Journal of biological chemistry.

Quinones are reduced by 6-tetrahydrobiopterin in human keratinocytes, melanocytes, and melanoma cells.

E. Cemeli, Diana Anderson, J. Wood, 2008, Free radical biology & medicine.

Estrogens can contribute to hydrogen peroxide generation and quinone-mediated DNA damage in peripheral blood lymphocytes from patients with vitiligo.

E. Cemeli, Diana Anderson, J. Wood, 2006, The Journal of investigative dermatology.

Selective affinity labeling of a 27-kDa integral membrane protein in rat liver and kidney with N-bromoacetyl derivatives of L-thyroxine and 3,5,3'-triiodo-L-thyronine.

J. Köhrle, U. Rasmussen, H. Rokos, 1990, The Journal of biological chemistry.

Effect of septicaemia on the plasma levels of biopterin and nitric oxide metabolites in rats and rabbits.

H. Rokos, J. Zuidema, J. T. te Biesebeek, 1996, Biochemical pharmacology.

Serum Biopterin as a Marker of Immune Activation in the Spontaneously Diabetic BB Rat

T. Galloway, H. Rokos, J. Braven, 1998 .

Thyroid hormone effect on rat heart mitochondrial proteins and affinity labeling with N‐bromoacetyl‐3,3′,5‐triiodo‐L‐thyronine Lack of direct effect on the adenine nucleotide translocase

J. Köhrle, U. Rasmussen, H. Rokos, 1989, FEBS letters.

Immunoenzymatic labeling of biopterin and neopterin in the pigment epithelium of bovine retina.

E. Vollmer, H. Gerding, H. Rokos, 1993, Advances in experimental medicine and biology.

The redox – biochemistry of human hair pigmentation

H. Rokos, K. Schallreuter, S. Hasse, 2011, Pigment cell & melanoma research.

H2O2 increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo

H. Ichinose, J. Wood, H. Rokos, 2009, Journal of Inherited Metabolic Disease.

Presence of epidermal allantoin further supports oxidative stress in vitiligo

N. J. Gibbons, J. Wood, H. Rokos, 2008, Experimental dermatology.

Methionine sulfoxide reductases A and B are deactivated by hydrogen peroxide (H2O2) in the epidermis of patients with vitiligo.

N. J. Gibbons, J. Wood, H. Rokos, 2008, The Journal of investigative dermatology.

GTP cyclohydrolase feedback regulatory protein controls cofactor 6-tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes.

H. Rokos, K. Schallreuter, J. Gillbro, 2006, The Journal of investigative dermatology.

A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin.

H. Rokos, K. Schallreuter, L. Marles, 2005, The Journal of endocrinology.

Molecular evidence that halo in Sutton’s naevus is not vitiligo

H. Rokos, K. Schallreuter, S. Hasse, 2003, Archives of Dermatological Research.

Determination of Sepiapterin and Sepiapterin Reductase in Human Skin

H. Rokos, K. Schallreuter, W. Beazley, 2002 .

Selenium-dependent regulation of type I 5'-deiodinase expression.

J. Köhrle, M. Oertel, H. Rokos, 1993, The American journal of clinical nutrition.

In vivo and in vitro evidence for epidermal H2O2‐mediated oxidative stress in piebaldism

H. Rokos, K. Schallreuter, Tayyebeh Vafaee, 2009, Experimental dermatology.

Senile hair graying: H2O2‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair

H Decker, R Paus, R. Paus, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Turmeric (curcumin): a widely used curry ingredient, can contribute to oxidative stress in Asian patients with acute vitiligo.

H. Rokos, K. Schallreuter, 2006, Indian journal of dermatology, venereology and leprology.

Decreased phenylalanine uptake and turnover in patients with vitiligo.

J. Wood, H. Rokos, K. Schallreuter, 2005, Molecular genetics and metabolism.

Oxidative stress in vitiligo: photo-oxidation of pterins produces H(2)O(2) and pterin-6-carboxylic acid.

H. Rokos, K. Schallreuter, Hartmut Rokos, 2002, Biochemical and biophysical research communications.

Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress.

N. J. Gibbons, H. Rokos, K. Schallreuter, 2004, The Journal of investigative dermatology.

Altered urinary excretion of pteridines in neoplastic disease. Determination of biopterin, neopterin, xanthopterin, and pterin.

H. Rokos, K. Rokos, H. Frisius, 1980, Clinica chimica acta; international journal of clinical chemistry.

Activation/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo.

N. J. Gibbons, J. Wood, H. Rokos, 2004, Biochemical and biophysical research communications.

In vitro and in vivo identification of ‘pseudocatalase’ activity in Dead Sea water using Fourier transform Raman spectroscopy

J. Wood, H. Rokos, K. Schallreuter, 2002 .

Oxidative stress via hydrogen peroxide affects proopiomelanocortin peptides directly in the epidermis of patients with vitiligo.

E. Peters, N. J. Gibbons, J. Wood, 2007, The Journal of investigative dermatology.

Butyrylcholinesterase is present in the human epidermis and is regulated by H2O2: more evidence for oxidative stress in vitiligo.

N. J. Gibbons, J. Wood, H. Rokos, 2006, Biochemical and biophysical research communications.

Basic research confirms coexistence of acquired Blaschkolinear Vitiligo and acrofacial Vitiligo

H. Rokos, S. Hasse, Hartmut Rokos, 2007, Archives of Dermatological Research.

Vitix®– a new treatment for vitiligo?

H. Rokos, K. Schallreuter, 2005, International journal of dermatology.

Blunted epidermal L‐tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: epidermal H2O2/ONOO–‐mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low serotonin and melatonin levels

Aurora Martínez, N. J. Gibbons, H. Rokos, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification of epidermal L‐tryptophan and its oxidation products by in vivo FT‐Raman Spectroscopy further supports oxidative stress in patients with vitiligo

J. Wood, H. Rokos, K. Schallreuter, 2008 .

Photo-Oxidation of Sepiapterin Produces Pterin-6-Carboxylic Acid and H 2 O 2 in Vitro

H. Rokos, K. Schallreuter, 2002 .

In vivo and in vitro evidence for autocrine DCoH/HNF‐1α transcription of albumin in the human epidermis

H. Rokos, S. Hasse, N. Schürer, 2005, Experimental dermatology.

In vivo fluorescence excitation spectroscopy and in vivo Fourier‐transform Raman spectroscopy in human skin: evidence of H2O2 oxidation of epidermal albumin in patients with vitiligo

J. Wood, H. Rokos, K. Schallreuter, 2004 .

From the bench to the bedside: proton pump inhibitors can worsen vitiligo

H. Rokos, K. Schallreuter, 2007, The British journal of dermatology.

Evidence for epidermal acetylcholine accumulation after oxidative stress by H2O2 and possible implications

J. Wood, H. Rokos, K. Schallreuter, 2008 .

Pteridine, XL. Zur Synthese von 3.N2.N2-Trimethyl-pterinen

H. Rokos, W. Pfleiderer, 1971 .

Correlations between endotoxin, interferon-gamma, biopterin and serum phospholipase A2-activities during lethal gram negative sepsis in rats.

H. Rokos, D. Lorenz, J. Petermann, 1997, The European journal of surgery = Acta chirurgica.

A Radioimmunoassay for Determination of D-Erythro- Neopterin

H. Rokos, K. Rokos, 1983 .

Raised serum neopterin levels and imbalances of T-lymphocyte subsets in viral diseases, acquired immune deficiency and related lymphadenopathy syndromes.

M. Dietrich, H. Rokos, P. Kern, 1984, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Endotoxin, Interferon-γ, Biopterin, Serum Phospholipase A2 Activity and β-Endorphin as Differentiation Factors and Their Correlations in the Acute Immune Response During Lethal Gram-Negative Sepsis in LEW Rats

H. Rokos, I. Klöting, D. Lorenz, 1995 .

Neopterin as parameter of cell-mediated immunity response in thermally injured patients.

H. Rokos, A. Grabosch, 1992, Burns : journal of the International Society for Burn Injuries.

Biosynthesis of riboflavin. 6,7-Dimethyl-8-ribityllumazine 5'-phosphate is not a substrate for riboflavin synthase.

A. Bacher, S. Ghisla, H. Rokos, 1978, Biochimica et biophysica acta.

ABSTRACTS 11th International Symposium on Chemistry and Biology of Pteridines and Folates

H. Rokos, W. Pfleiderer, Konstanz Rokos, 1997 .

Rapid stimulation of hepatic oxygen consumption by 3,5-di-iodo-L-thyronine.

H. Rokos, H. Seitz, C. Horst, 1989, The Biochemical journal.

DETERMINATION OF NEOPTERIN AND REDUCED NEOPTERINS BY RADIOIMMUNOASSAY

H. Rokos, A. Gadow, K. Rokos, 1985 .

Synthetic flavonoids cross the placenta in the rat and are found in fetal brain.

G. D. de Escobar, J. Köhrle, H. Rokos, 1998, American journal of physiology. Endocrinology and metabolism.

Different Tissue Distribution, Elimination, and Kinetics of Thyroxine and Its Conformational Analog, the Synthetic Flavonoid EMD 49209 in the Rat1.

H. Rokos, G. Morreale de Escobar, J. Ko Hrle, 1997, Endocrinology.

Different tissue distribution, elimination, and kinetics of thyroxine and its conformational analog, the synthetic flavonoid EMD 49209 in the rat.

J. Köhrle, H. Rokos, G. Morreale de Escobar, 1997, Endocrinology.

Molecular structure and biochemical activity of 3,5,3'-triiodothyronamine.

V. Cody, H. Rokos, R. Hesch, 1984, Endocrine research.

3,5-Di-iodo-L-thyronine suppresses TSH in rats in vivo and in rat pituitary fragments in vitro.

H. Rokos, H. Seitz, A. Harneit, 1995, The Journal of endocrinology.

Pteridines in Cancer and Other Diseases

M. Hüfner, H. Rokos, K. Rokos, 1983 .

The redox – biochemistry of human hair pigmentation

H. Rokos, K. Schallreuter, S. Hasse, 2011, Pigment cell & melanoma research.