A. Faucher

发表

Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors.

P. Bonneau, C. Yoakim, S. LaPlante, 2007, Bioorganic & medicinal chemistry letters.

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

Steven R. LaPlante, P. Bonneau, D. Lamarre, 2003, Nature.

Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor

J. Duan, M. Garneau, P. Bonneau, 2014, Antimicrobial Agents and Chemotherapy.

Novel inhibitor binding site discovery on HIV-1 capsid N-terminal domain by NMR and X-ray crystallography.

J. Mercier, J. Rancourt, S. Titolo, 2013, ACS chemical biology.

Biphenylsulfonacetic Acid Inhibitors of the Human Papillomavirus Type 6 E1 Helicase Inhibit ATP Hydrolysis by an Allosteric Mechanism Involving Tyrosine 486

J. Rancourt, M. Massariol, E. Welchner, 2005, Antimicrobial Agents and Chemotherapy.

Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase.

M. Garneau, M. Cordingley, A. Faucher, 2004, Antiviral research.

POPULATION ANALYSIS OF NORTHERN BOTTLENOSE WHALES IN THE GULLY, NOVA SCOTIA

H. Whitehead, A. Faucher, Shannon Gowans, 1997 .

Landscape Transformation During Ceramic Age and Colonial Occupations of Barbuda, West Indies

A. Faucher, A. Bain, R. Boger, 2018 .

Status of the Northern Bottlenose Whale, Hyperoodon ampullatus, in the Gully, Nova Scotia

H. Whitehead, A. Faucher, Shannon Gowans, 1997 .

Potent inhibitors of the hepatitis C virus NS3 protease: design and synthesis of macrocyclic substrate-based beta-strand mimics.

C. Brochu, M. Poirier, Y. Tsantrizos, 2004, The Journal of organic chemistry.

An NS 3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

P. Bonneau, D. Lamarre, P. Anderson, 2003 .

Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase.

C. Brochu, J. Rancourt, P. White, 2004, Journal of medicinal chemistry.

An NS 3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

P. Bonneau, D. Lamarre, P. Anderson, 2003 .

First Archaeological Evidence for Old World Crops in the Caribbean: The Presence of Barley on the Island of Barbuda

V. Grimes, A. Faucher, A. Bain, 2017 .

tris(2-Carboxyethyl)phosphine (TCEP) for the Reduction of Sulfoxides, Sulfonylchlorides, N-Oxides, and Azides

A. Faucher, C. Grand-Maître, 2003 .

Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly.

O. Hucke, P. Bonneau, C. Yoakim, 2011, Bioorganic & medicinal chemistry letters.

Structure-activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061.

Martin Poirier, M. Garneau, D. Lamarre, 2004, Journal of medicinal chemistry.

Discovery and structural characterization of a new inhibitor series of HIV-1 nucleocapsid function: NMR solution structure determination of a ternary complex involving a 2:1 inhibitor/NC stoichiometry.

O. Hucke, P. Bonneau, S. Titolo, 2013, Journal of molecular biology.

Monitoring Binding of HIV‐1 Capsid Assembly Inhibitors Using 19F Ligand‐and 15N Protein‐Based NMR and X‐ray Crystallography: Early Hit Validation of a Benzodiazepine Series

Jean-François Mercier, Yves Bousquet, J. Mercier, 2013, ChemMedChem.

Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein

Wesley I. Sundquist, Stephen W. Mason, W. Sundquist, 2012, Journal of Virology.

Preparation of Chiral Bisoxazolines: Observations on the Effect of Substituents

J. Edwards, S. Denmark, N. Nakajima, 1995 .

Cyclopropanation with Diazomethane and Bis(oxazoline)palladium(II) Complexes.

J. Edwards, S. Denmark, R. Stavenger, 1997, The Journal of organic chemistry.

Cyclofunctionalization and free-radical-based hydrogen-transfer reactions. An iterative reaction sequence applied to the synthesis of the C(7)-C(16) subunit of zincophorin.

B. Guérin, A. Faucher, S. Landry, 2001, The Journal of organic chemistry.

Synthesis of BILN 2061, an HCV NS3 protease inhibitor with proven antiviral effect in humans.

Martin Poirier, C. Brochu, M. Poirier, 2004, Organic letters.

Total synthesis of (+)-meroquinene

S. Léger, S. Hanessian, A. Faucher, 1990 .

On the generation and configurational stability of (2S,3S)-1,2,3-triphenylborirane

S. Denmark, A. Faucher, K. Nishide, 1991 .

Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease

M. Cordingley, A. Faucher, B. Simoneau, 2002, Nature Medicine.

Small molecule inhibitors of the human papillomavirus E1-E2 interaction.

P. White, A. Faucher, N. Goudreau, 2011, Current topics in microbiology and immunology.

The Exocyclic Effect: Protecting Group Strategy to Enhance Stereoselectivity in Hydrogen Transfer Reactions of Acyclic Free Radicals

A. Faucher, S. Landry, Y. Guindon, 1997 .

Chelation-controlled reduction of α- and β-oxygenated ketones with lithium tri-n-butylborohydride

Claude Y. Legault, C. Brochu, A. Faucher, 1998 .

Oral Bioavailability and In Vivo Efficacy of the Helicase-Primase Inhibitor BILS 45 BS against Acyclovir-Resistant Herpes Simplex Virus Type 1

J. Duan, M. Cordingley, A. Faucher, 2003, Antimicrobial Agents and Chemotherapy.

Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1.

Araz Jakalian, Sébastien Morin, Yves Bousquet, 2014, ACS medicinal chemistry letters.

First Archaeological Evidence for Old World Crops in the Caribbean: The Presence of Barley on the Island of Barbuda

V. Grimes, A. Faucher, Allison Bain, 2017, Historical Archaeology.

Evaluation of Phosphatidylinositol-4-Kinase IIIα as a Hepatitis C Virus Drug Target

G. Kukolj, P. White, M. Cordingley, 2012, Journal of Virology.

Observations on the birth of a beluga whale (Delphinapterus leucas) in the St. Lawrence Estuary, Quebec, Canada

A. Faucher, P. Béland, Patrice Corbeil, 1990 .

A novel inhibitor-binding site on the HIV-1 capsid N-terminal domain leads to improved crystallization via compound-mediated dimerization.

P. Bonneau, S. Titolo, A. Faucher, 2013, Acta crystallographica. Section D, Biological crystallography.