J. Swarbrick

发表

Discovery of inhibitors of lupin diadenosine 5',5'''-P(1),P(4)-tetraphosphate hydrolase by virtual screening.

Brian J. Smith, H. Mertens, J. Fletcher, 2009, Biochemistry.

Small neutral Gd(iii) tags for distance measurements in proteins by double electron-electron resonance experiments.

G. Otting, D. Goldfarb, J. Swarbrick, 2018, Physical chemistry chemical physics : PCCP.

An iminodiacetic acid based lanthanide binding tag for paramagnetic exchange NMR spectroscopy.

J. Swarbrick, B. Graham, Sandeep Chhabra, 2011, Angewandte Chemie.

Letter to the Editor: Backbone resonance assignment of the 2H, 13C, 15N labelled 32kDa central domain of Escherichia coli TyrR

B. E. Davidson, J. Swarbrick, P. Gooley, 2002, Journal of biomolecular NMR.

The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study

D. Hoyer, J. Li, T. Velkov, 2020, mSystems.

Dynamic Binding Mode of a Synaptotagmin-1-SNARE Complex in Solution

T. Südhof, J. Rizo, A. Cavalli, 2015, Nature Structural &Molecular Biology.

Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

J. Newman, T. Peat, R. Fernley, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling*

M. O’Bryan, J. Swarbrick, M. Scanlon, 2006, Journal of Biological Chemistry.

Complex with a Collagen-mimetic Peptide 1 I Domain in α The Structure of Integrin Protein Structure and Folding :

P. McEwan, J. Emsley, T. Mulhern, 2013 .

Small Gd(III) Tags for Gd(III)-Gd(III) Distance Measurements in Proteins by EPR Spectroscopy.

G. Otting, D. Goldfarb, J. Swarbrick, 2018, Inorganic chemistry.

Overcoming artificial broadening in Gd(3+)-Gd(3+) distance distributions arising from dipolar pseudo-secular terms in DEER experiments.

G. Otting, V. Frydman, D. Goldfarb, 2016, Physical chemistry chemical physics : PCCP.

Letter to the Editor: 1H, 13C, and 15N resonance assignments of the 17 kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP

Brian J. Smith, A. McLennan, J. Fletcher, 2005, Journal of biomolecular NMR.

Structure-activity relationships of daptomycin lipopeptides.

T. Velkov, M. Baker, Jian Li, 2020, Journal of medicinal chemistry.

Dictyostelium discoideum as expression host: isotopic labeling of a recombinant glycoprotein for NMR studies.

P. Curmi, A. Gooley, K. Williams, 2000, Protein expression and purification.

Simulations of octapeptin–outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency

F. Schreiber, J. Li, Lushan Wang, 2020, The Journal of Biological Chemistry.

Sequence-specific assignment of methyl groups from the neuronal SNARE complex using lanthanide-induced pseudocontact shifts

J. Rizo, B. Quade, J. Swarbrick, 2016, Journal of biomolecular NMR.

Short two-armed lanthanide-binding tags for paramagnetic NMR spectroscopy based on chiral 1,4,7,10-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane scaffolds.

J. Swarbrick, M. Dennis, B. Graham, 2017, Chemical communications.

An NMR study of the solution conformations of di(tertiary phosphine) complexes of orthopalladated 1-phenyl-1-(N,N-dimethylamino)ethane

J. Swarbrick, W. Mcfarlane, J. L. Bookham, 1998 .

Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy.

G. Otting, T. Huber, X. Su, 2011, Chemical communications.

RIDME distance measurements using Gd(iii) tags with a narrow central transition.

G. Otting, V. Frydman, D. Goldfarb, 2016, Physical chemistry chemical physics : PCCP.

Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli.

J. Baell, Zhong-Chang Wang, T. Peat, 2016, Journal of medicinal chemistry.

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor

J. Newman, T. Peat, R. Fernley, 2012, PloS one.

Synthesis and structure−activity relationships of teixobactin

D. Hoyer, J. Li, R. Payne, 2019, Annals of the New York Academy of Sciences.

The impact of backbone N‐methylation on the structure‐activity relationship of Leu10‐teixobactin

D. Hoyer, J. Li, T. Velkov, 2019, Journal of peptide science : an official publication of the European Peptide Society.

The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study

Jian Li, J. Swarbrick, Yan Zhu, 2020 .

Metal complexes as tools for structural biology

J. Swarbrick, Michael D. Lee, Bimbil Graham, 2014 .

NMR studies of dextromethorphan in both isotropic and anisotropic states.

J. Swarbrick, T. Ashton, 2010, Chirality.

Folate Biosynthesis – Reappraisal of Old and Novel Targets in the Search for New Antimicrobials

P. Iliades, I. Macreadie, J. Swarbrick, 2008 .

A New Gd(3+) Spin Label for Gd(3+)-Gd(3+) Distance Measurements in Proteins Produces Narrow Distance Distributions.

G. Otting, D. Goldfarb, J. Swarbrick, 2015, The journal of physical chemistry letters.

DOTA-amide lanthanide tag for reliable generation of pseudocontact shifts in protein NMR spectra.

Thomas Huber, Guido Pintacuda, Gottfried Otting, 2011, Bioconjugate chemistry.

Double-Arm Lanthanide Tags Deliver Narrow Gd3+ -Gd3+ Distance Distributions in Double Electron-Electron Resonance (DEER) Measurements.

G. Otting, T. Huber, D. Goldfarb, 2017, Chemistry.

New Lanthanide Tag for the Generation of Pseudocontact Shifts in DNA by Site-Specific Ligation to a Phosphorothioate Group.

G. Otting, J. Swarbrick, M. Dennis, 2017, Bioconjugate chemistry.

Kv1.3 channel‐blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

P. Hotez, K. Chandy, G. Gutman, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase*

A. McLennan, J. Swarbrick, K. Gayler, 2005, Journal of Biological Chemistry.

NMR assignment of prespore specific antigen—a cell surface adhesion glycoprotein from Dictyostelium discoideum

P. Curmi, A. Gooley, K. Williams, 2009, Biomolecular NMR assignments.

Fragment Screening on Staphylococcus aureus HPPK – a Folate Pathway Target

T. Peat, O. Dolezal, J. Swarbrick, 2013 .

Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria

Jesmin Akter, J. Li, R. Nation, 2014, Bioconjugate chemistry.

The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide*

P. McEwan, J. Emsley, T. Mulhern, 2013, The Journal of Biological Chemistry.

Exploring the Chemical Space around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme HPPK

J. Newman, T. Peat, O. Dolezal, 2013, PloS one.

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

H. Mertens, J. Li, R. Nation, 2018, Cell chemical biology.

1 Dynamic Synaptotagmin-1-SNARE Complex Binding Mode in Solution

T. Südhof, J. Rizo, A. Cavalli, 2015 .

VPS29 Is Not an Active Metallo-Phosphatase but Is a Rigid Scaffold Required for Retromer Interaction with Accessory Proteins

E. Valkov, B. Collins, J. Swarbrick, 2011, PloS one.

Structure of micelle bound cationic peptides by NMR spectroscopy using a lanthanide shift reagent.

J. Li, T. Velkov, J. Swarbrick, 2020, Chemical communications.

Integral membrane protein structure determination using pseudocontact shifts

Daniel Nietlispach, D. Nietlispach, H. Mott, 2015, Journal of biomolecular NMR.

The structure of Ap(4)A hydrolase complexed with ATP-MgF(x) reveals the basis of substrate binding.

J. Fletcher, J. Swarbrick, K. Gayler, 2002, Structure.

Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius.

J. Swarbrick, K. Gayler, P. Gooley, 2001, The Biochemical journal.

The three-dimensional structure of the Nudix enzyme diadenosine tetraphosphate hydrolase from Lupinus angustifolius L.

J. Swarbrick, K. Gayler, P. Gooley, 2000, Journal of molecular biology.

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

J. Baell, Zhong-Chang Wang, J. Newman, 2014, Journal of medicinal chemistry.

Installation of a Rigid EDTA-Like Motif into a Protein α-Helix for Paramagnetic NMR Spectroscopy with Cobalt(II) Ions.

J. Swarbrick, M. Dennis, B. Graham, 2016, Chemistry.

A high‐resolution solution structure of a trypanosomatid FYVE domain

H. Mertens, M. McConville, J. Swarbrick, 2007, Protein science : a publication of the Protein Society.

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.

J. Baell, Zhong-Chang Wang, T. Peat, 2018, Chemistry.

New Lanthanide Tag for the Generation of Pseudocontact Shifts in DNA by Site-Specific Ligation to a Phosphorothioate Group.

G. Otting, J. Swarbrick, M. Dennis, 2017, Bioconjugate chemistry.

Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy.

G. Otting, T. Huber, J. Swarbrick, 2011, Chemical communications.