P. Gooley

发表

Discovery of inhibitors of lupin diadenosine 5',5'''-P(1),P(4)-tetraphosphate hydrolase by virtual screening.

Brian J. Smith, H. Mertens, J. Fletcher, 2009, Biochemistry.

Assignment of aromatic resonances in the 1H nuclear magnetic resonance spectra of cardioactive polypeptides from sea anemones.

R. Norton, P. Gooley, J. Blunt, 1986, The Journal of biological chemistry.

Native Chemical Ligation to Minimize Aspartimide Formation during Chemical Synthesis of Small LDLa Protein.

J. Wade, P. Gooley, J. Tailhades, 2016, Chemistry.

Applications of NMR spectroscopy to biological systems

P. Gooley, N. Mackenzie, 1988, Medicinal research reviews.

Letter to the Editor: Backbone resonance assignment of the 2H, 13C, 15N labelled 32kDa central domain of Escherichia coli TyrR

B. E. Davidson, J. Swarbrick, P. Gooley, 2002, Journal of biomolecular NMR.

Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

A. Reményi, A. Zeke, A. Alexa, 2020, Nature Communications.

Regulation of Cell Signaling Pathways When phosphorylated at Thr 148 , the 2-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle

G. Lamb, N. Frankenberg, D. Stapleton, 2016 .

Probing the correlation between ligand efficacy and conformational diversity at the α1A-adrenoreceptor reveals allosteric coupling of its microswitches

P. Gooley, M. Griffin, R. Bathgate, 2020, The Journal of Biological Chemistry.

Expression and Purification of a Functional E. coli 13CH3-Methionine-Labeled Thermostable Neurotensin Receptor 1 Variant for Solution NMR Studies.

P. Gooley, F. Bumbak, R. Bathgate, 2019, Methods in molecular biology.

Determinants of Ligand Subtype-Selectivity at α1A-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR.

A. Plückthun, P. Gooley, R. Bathgate, 2018, ACS chemical biology.

Comparison of the structure of human recombinant short form stromelysin by multidimensional heteronuclear NMR and X-ray crystallography

Paul R. Gooley, Melinda G. Axel, J. W. Becker, 1996, Journal of biomolecular NMR.

The relaxin receptor as a therapeutic target – perspectives from evolution and drug targeting

P. Gooley, J. Bogerd, R. Bathgate, 2018, Pharmacology & therapeutics.

Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases

D. P. Lewis, Donald P. Lewis, P. Gooley, 2019, Diagnostics.

INPHARMA based determination of ligand binding modes at α1-adrenergic receptors explains the molecular basis of subtype selectivity.

D. Chalmers, P. Gooley, D. Scott, 2020, Chemistry.

Structure, topology and function of the translocase of the outer membrane of mitochondria.

R. Waller, T. Lithgow, H. Mertens, 2008, Plant physiology and biochemistry : PPB.

Polymorphism in disease‐related apolipoprotein C‐II amyloid fibrils: a structural model for rod‐like fibrils

G. Howlett, P. Gooley, I. Yarovsky, 2018, The FEBS journal.

The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement

M. Parker, C. Morton, R. Dobson, 2020, The Journal of Biological Chemistry.

Heteronuclear NMR spectroscopy of proteins encapsulated in cubic phase lipids.

S. Yao, C. Conn, P. Gooley, 2019, Journal of magnetic resonance.

The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome

D. P. Lewis, Donald P. Lewis, P. Gooley, 2016, Metabolomics.

Location of an alpha-helix in fragment 96-133 from bovine somatotropin by 1H NMR spectroscopy.

P. Gooley, N. Mackenzie, 1988, Biochemistry.

Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody

John P. Moore, D. Montefiori, D. Purcell, 2022, Cell reports. Medicine.

Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.

M. Parker, D. Stapleton, M. Gorman, 2015, The Biochemical journal.

Multiple heparin binding domains of respiratory syncytial virus G mediate binding to mammalian cells

J. Mills, R. Ghildyal, P. Gooley, 2003, Archives of Virology.

Widespread pain and altered renal function in ME/CFS patients

D. P. Lewis, Donald P. Lewis, P. Gooley, 2016 .

Metabolism in chronic fatigue syndrome.

P. Gooley, H. Butt, N. McGregor, 2014, Advances in clinical chemistry.

When phosphorylated at Thr148, the β2-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle.

G. Lamb, N. Frankenberg, D. Stapleton, 2016, American journal of physiology. Cell physiology.

The interaction of human apolipoprotein C-I with sub-micellar phospholipid.

G. Howlett, P. Gooley, C. MacRaild, 2001, European journal of biochemistry.

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length.

R. Pappu, A. Purcell, A. Fox, 2018, Journal of molecular biology.

Tadpole-like conformations of huntingtin exon 1 with expanded polyglutamine engenders novel interactions in cells

R. Pappu, A. Purcell, A. Fox, 2017, bioRxiv.

Structural characterization of the N‐terminal autoregulatory sequence of phenylalanine hydroxylase

B. Kobe, T. Teh, I. Jennings, 2002, Protein science : a publication of the Protein Society.

relaxGUI: a new software for fast and simple NMR relaxation data analysis and calculation of ps-ns and μs motion of proteins

Edward J. d'Auvergne, P. Gooley, M. Bieri, 2011, Journal of biomolecular NMR.

Model-free model elimination: A new step in the model-free dynamic analysis of NMR relaxation data

Edward J. d'Auvergne, P. Gooley, 2006, Journal of biomolecular NMR.

The Human LGR7 Low‐Density Lipoprotein Class A Module Requires Calcium for Structure

P. Gooley, R. Bathgate, Emma J. Hopkins, 2005, Annals of the New York Academy of Sciences.

A structural model for apolipoprotein C-II amyloid fibrils: experimental characterization and molecular dynamics simulations.

C. L. Teoh, S. Radford, A. Engel, 2011, Journal of molecular biology.

N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation

P. Gooley, D. Cox, H. Ecroyd, 2020, The Journal of Biological Chemistry.

A Dynamic Pharmacophore Drives the Interaction between Psalmotoxin-1 and the Putative Drug Target Acid-Sensing Ion Channel 1a

A. Mark, R. Gamsjaeger, G. King, 2011, Molecular Pharmacology.

Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface.

Md. Alamgir Hossain, G. Moseley, K. G. Lieu, 2019, Cell reports.

Ligands tune the local and global motions of neurotensin receptor 1 (NTS1): a DFT-guided solution NMR analysis

M. Pons, A. Inoue, P. Gooley, 2022, bioRxiv.

Validating the use of database potentials in protein structure determination by NMR

H. Mertens, P. Gooley, 2005, FEBS letters.

Systematic Review of NMR-Based Metabolomics Practices in Human Disease Research

P. Gooley, C. Armstrong, Katherine Huang, 2022, Metabolites.

The structure and interactions of human apolipoprotein C-II in dodecyl phosphocholine.

G. Howlett, P. Gooley, C. MacRaild, 2004, Biochemistry.

Structural comparison of the C-terminal domain of functionally divergent lyssavirus P proteins.

G. Moseley, M. Yao, P. Gooley, 2020, Biochemical and biophysical research communications.

The NMR Solution Structure of the Relaxin (RXFP1) Receptor Lipoprotein Receptor Class A Module and Identification of Key Residues in the N-terminal Region of the Module That Mediate Receptor Activation*

P. Gooley, R. Bathgate, S. Layfield, 2006, Journal of Biological Chemistry.

Comparison of amide proton exchange in reduced and oxidizedRhodobacter capsulatus cytochrome c2: A1H−15N NMR study

Dezheng Zhao, P. Gooley, N. Mackenzie, 1991, Journal of biomolecular NMR.

The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9

G. Moseley, M. Yao, Takashi Tadokoro, 2020, Journal of Virology.

Specific assignment of resonances in the 1H‐nmr spectrum of the polypeptide toxin I from Anemonia sulcata

R. Norton, P. Gooley, 1986, Biopolymers.

Letter to the Editor: 1H, 13C, and 15N resonance assignments of the 17 kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP

Brian J. Smith, A. McLennan, J. Fletcher, 2005, Journal of biomolecular NMR.

The monomeric α-crystallin domain of the small heat-shock proteins αB-crystallin and Hsp27 binds amyloid fibril ends.

P. Gooley, H. Ecroyd, M. Griffin, 2022, Journal of molecular biology.

The underlying sex differences in neuroendocrine adaptations relevant to Myalgic Encephalomyelitis Chronic Fatigue Syndrome

N. Thomas, P. Gooley, C. Gurvich, 2022, Frontiers in Neuroendocrinology.

Unravelling the Carbohydrate‐Binding Preferences of the Carbohydrate‐Binding Modules of AMP‐Activated Protein Kinase

D. Stapleton, P. Gooley, M. Griffin, 2018, Chembiochem : a European journal of chemical biology.

Charge and charge-pair mutations alter the rate of assembly and structural properties of apolipoprotein C-II amyloid fibrils.

C. L. Teoh, G. Howlett, P. Gooley, 2015, Biochemistry.

Development of a scaffold displaying exoloops of RXFP1.

M. Stone, P. Gooley, R. Bathgate, 2013, Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia.

Structures of the interleukin 11 signalling complex reveal dynamics of gp130 extracellular domains and the inhibitory mechanism of a cytokine variant

C. Morton, E. Hanssen, P. Gooley, 2022, bioRxiv.

The dynamic nature of neurotensin receptor 1 (NTS1) allostery and signaling bias

M. Pons, A. Inoue, P. Gooley, 2022, bioRxiv.

The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome

D. P. Lewis, Donald P. Lewis, P. Gooley, 2016, Metabolomics.

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding.

Jong-Tae Park, D. Neumann, D. Stapleton, 2012, Biophysical journal.

ROLE OF MONOTERPENES IN GRAPE AND WINE FLAVOR

P. Gooley, Patrick J. Williams, C. R. Strauss, 1986 .

Conformational Changes in Tyrosine 11 of Neurotensin Are Required to Activate the Neurotensin Receptor 1.

Margaret A. Johnson, Trayder Thomas, D. Chalmers, 2020, ACS pharmacology & translational science.

The NMR structure of the inhibited catalytic domain of human stromelysin–1

J. Springer, J. Hermes, P. Gooley, 1994, Nature Structural Biology.

Esterification of high amylose starch with short chain fatty acids modulates degradation by Bifidobacterium spp

S. Gras, P. Gooley, C. McSweeney, 2014 .

Physical characterisation of high amylose maize starch and acylated high amylose maize starches.

P. Gooley, Danyang Ying, M. Augustin, 2015, Carbohydrate polymers.

Macromolecular NMR spectroscopy for the non‐spectroscopist: beyond macromolecular solution structure determination

Mehdi Mobli, Michael Bieri, Joel P Mackay, 2011, The FEBS journal.

Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS1)

M. Pons, A. Inoue, P. Gooley, 2023, Cell reports.

Optimization and 13CH3 methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies.

P. Gooley, F. Bumbak, R. Bathgate, 2018, Biochimica et biophysica acta. Biomembranes.

Macromolecular NMR spectroscopy for the non‐spectroscopist

Mehdi Mobli, J. Mackay, A. Kwan, 2011, The FEBS journal.

Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL

Cheree Fitzgibbon, J. Hildebrand, P. Gooley, 2021, Cell Death & Differentiation.

Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1)*

Catherine Z. Chen, A. Wang, P. Gooley, 2014, The Journal of Biological Chemistry.

Microsoft Word-32106277-file00

A. Mark, A. Malde, P. Gooley, 2011 .

Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

W. Low, P. Batterham, C. Robin, 2010, Journal of molecular biology.

Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20.

R. Waller, T. Lithgow, P. Keeling, 2005, Journal of molecular biology.

In a Class of Their Own – RXFP1 and RXFP2 are Unique Members of the LGR Family

P. Gooley, Ashish Sethi, E. Petrie, 2015, Front. Endocrinol..

Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation.

J. Wade, P. Gooley, E. Petrie, 2014, Biochemistry.

Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients

D. P. Lewis, Donald P. Lewis, P. Gooley, 2015, Metabolomics.

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome.

P. Gooley, H. Butt, N. McGregor, 2012, Clinica chimica acta; international journal of clinical chemistry.

Nutrient copper signaling promotes protein turnover by allosteric activation of ubiquitin E2D conjugases

A. Bush, Z. Xiao, D. Saunders, 2021, bioRxiv.

A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine.

Paul R Gooley, Peter R Ebeling, P. Ebeling, 2010, Analytical biochemistry.

Definition of the immune evasion-replication interface of rabies virus P protein

G. Moseley, D. Ascher, P. Gooley, 2021, PLoS pathogens.

Molecular Basis of Functional Effects of Phosphorylation of the C-Terminal Domain of the Rabies Virus P Protein

G. Moseley, P. Gooley, Aaron M. Brice, 2022, Journal of virology.

Letter to the Editor: 1H, 13C and 15N backbone assignment and secondary structure of the 19 kDa diadenosine 5′, 5′′′-P1, P4-tetraphosphate hydrolase from Lupinus angustifolius L.

P. Gooley, R. Pau, James D. Swarbrick, 2000, Journal of biomolecular NMR.

Recognition of mitochondrial targeting sequences by the import receptors Tom20 and Tom22.

T. Lithgow, H. Mertens, T. Mulhern, 2011, Journal of molecular biology.

Convergent Evolution of Receptors for Protein Import into Mitochondria

T. Lithgow, P. Gooley, A. Perry, 2006, Current Biology.

AMPK β subunits display isoform specific affinities for carbohydrates

S. Ralph, M. Bailey, Jong-Tae Park, 2010, FEBS letters.

Hydrodynamic radii of solubilized high amylose native and modified starches by pulsed field gradient NMR diffusion measurements

S. Yao, S. Gras, P. Gooley, 2014 .

Membrane receptors: Structure and function of the relaxin family peptide receptors

P. Gooley, Patrick J. Shilling, D. Lobb, 2010, Molecular and Cellular Endocrinology.

Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces

Edward J. d'Auvergne, P. Gooley, 2007, Journal of biomolecular NMR.

Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor

Edward J. d'Auvergne, P. Gooley, 2007, Journal of biomolecular NMR.

The transmembrane segment of Tom20 is recognized by Mim1 for docking to the mitochondrial TOM complex.

T. Lithgow, P. Gooley, A. Perry, 2008, Journal of molecular biology.

Biologically active Arg-Gly-Asp oligopeptides assume a type II beta-turn in solution.

C. Basson, P. Gooley, J. Madri, 1993, Biochemistry.

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.

Laura F. Dagley, Christopher J. Tonkin, A. Bacic, 2015, Cell host & microbe.

The Role of Select Subtype Polymorphisms on HIV-1 Protease Conformational Sampling and Dynamics*

Carlos Simmerling, C. D. Boone, Michael Bieri, 2014, The Journal of Biological Chemistry.

Probing the flexibility of the DsbA oxidoreductase from Vibrio cholerae--a 15N - 1H heteronuclear NMR relaxation analysis of oxidized and reduced forms of DsbA.

Edward J. d'Auvergne, T. Velkov, R. Prankerd, 2007, Journal of molecular biology.

Set theory formulation of the model-free problem and the diffusion seeded model-free paradigm.

Edward J. d'Auvergne, Edward J d'Auvergne, Paul R Gooley, 2007, Molecular bioSystems.

The use of model selection in the model-free analysis of protein dynamics

Paul R. Gooley, Edward J. d'Auvergne, P. Gooley, 2003, Journal of biomolecular NMR.

Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

B. Kemp, T. Iseli, S. Jørgensen, 2008, Chemistry & biology.

Membrane protein SMP-1 is required for normal flagellum function in Leishmania

G. McFadden, H. Mertens, M. McConville, 2010, Journal of Cell Science.

Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase*

A. McLennan, J. Swarbrick, K. Gayler, 2005, Journal of Biological Chemistry.

Solving solution structures of physiologically relevant proteins by NMR spectroscopy.

P. Gooley, N. Mackenzie, L. A. Hardaway, 1992, Annual review of physiology.

Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome.

D. P. Lewis, Donald P. Lewis, D. Stapleton, 2009, In vivo.

Characterisation of a cell-free synthesised G-protein coupled receptor

P. Gooley, F. Bumbak, R. Bathgate, 2017, Scientific Reports.

Bugs and Brains, the Gut and Mental Health Study: a mixed-methods study investigating microbiota composition and function in anxiety, depression and irritable bowel syndrome

N. Haslam, S. Whittle, J. Simmons, 2021, BMJ Open.

A statistical approach to the interpretation of molecular dynamics simulations of calmodulin equilibrium dynamics

Terence P Speed, Paul R Gooley, T. Speed, 2005, Protein science : a publication of the Protein Society.

Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases.

B. Kobe, J. Heierhorst, T. Teh, 2001, Acta crystallographica. Section D, Biological crystallography.

Dynamics of Ca2+‐saturated calmodulin D129N mutant studied by multiple molecular dynamics simulations

P. Gooley, E. Strehler, V. Likic, 2003, Protein science : a publication of the Protein Society.

(1)H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium-vitamin-D3 supplementation in older men.

Amsha Nahid, Paul R Gooley, Peter R Ebeling, 2014, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds.

Martin J. Stoermer, D. Fairlie, M. Bogoyevitch, 2013, Biochimica et biophysica acta.

The Recruitment of AMP-activated Protein Kinase to Glycogen Is Regulated by Autophosphorylation

Ramon F. Thali, R. Scholz, D. Neumann, 2015, The Journal of Biological Chemistry.

Oligosaccharide recognition and binding to the carbohydrate binding module of AMP‐activated protein kinase

H. Mertens, D. Stapleton, P. Gooley, 2007, FEBS letters.

β-subunit myristoylation functions as an energy sensor by modulating the dynamics of AMP-activated Protein Kinase

B. Kemp, G. Anand, D. Stapleton, 2016, Scientific Reports.

NMR applications to GPCR recognition by peptide ligands.

P. Gooley, Kazem Asadollahi, D. Scott, 2023, Current opinion in pharmacology.

Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1.

A. Bacic, M. Doblin, D. Stapleton, 2016, Trends in plant science.

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1

P. Gooley, Ashish Sethi, N. Patil, 2016, Nature Communications.

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Quentin Kaas, Paul R. Gooley, Ross A. D. Bathgate, 2013, Front. Endocrin..

A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.

J. Wade, H. Mertens, G. Howlett, 2007, Journal of molecular biology.

SnRK1 from Arabidopsis thaliana is an atypical AMPK.

Monika S. Doblin, A. Bacic, B. Kemp, 2015, The Plant journal : for cell and molecular biology.

Structural insights into the unique modes of relaxin-binding and tethered-agonist mediated activation of RXFP1 and RXFP2.

P. Gooley, Ashish Sethi, M. Griffin, 2021, Journal of molecular biology.

Structural insights into the modes of relaxin-binding and tethered-agonist activation of RXFP1 and RXFP2

P. Gooley, Mohammad Tanipour, Ashish Sethi, 2021, bioRxiv.

Pro → Ala‐35 Rhodobacter capsulatus cytochrome c 2 shows dynamic not structural differences

P. Gooley, N. Mackenzie, 1990, FEBS letters.

D. Zhao, P. Gooley, M. Cusanovich, 2000, Protein science : a publication of the Protein Society.

Solution Conditions Affect the Ability of the K30D Mutation To Prevent Amyloid Fibril Formation by Apolipoprotein C-II: Insights from Experiments and Theoretical Simulations.

G. Howlett, P. Gooley, I. Yarovsky, 2016, Biochemistry.

A cyclic peptide inhibitor of apoC-II peptide fibril formation: mechanistic insight from NMR and molecular dynamics analysis.

G. Howlett, P. Gooley, I. Yarovsky, 2012, Journal of molecular biology.

The NMR solution structure and characterization of pH dependent chemical shifts of the β-elicitin, cryptogein

R. Dimitrov, B. Grant, K. Gayler, 1998 .

α1A-adrenoceptor inverse agonists and agonists modulate receptor signalling through a conformational selection mechanism

P. Gooley, M. Griffin, R. Bathgate, 2019, bioRxiv.

Diazepam is not a direct allosteric modulator of α1‐adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase‐4

Spencer J. Williams, P. Gooley, R. Bathgate, 2018, Pharmacology research & perspectives.

Application of droplet countercurrent chromatography to the analysis of conjugated forms of terpenoids, phenols, and other constituents of grape juice

P. Gooley, C. R. Strauss, B. Wilson, 1987 .

Effects of pH and temperature on cardioactive polypeptides from sea anemones: A 1H‐nmr study

R. Norton, P. Gooley, J. Blunt, 1988, Biopolymers.

Enhanced protein fold recognition using secondary structure information from nmr

A. Torda, P. Gooley, Paul R. Gooley, 1999, Protein science : a publication of the Protein Society.

Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients

D. P. Lewis, P. Gooley, H. Butt, 2015, Metabolomics.

Single fiber analyses of glycogen-related proteins reveal their differential association with glycogen in rat skeletal muscle.

D. Stapleton, P. Gooley, R. Murphy, 2012, American journal of physiology. Cell physiology.

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules

J. Wade, P. Gooley, E. Petrie, 2013, Front. Endocrinol..

Recombinant RXFP1-LDL-A module does not form dimers.

P. Gooley, E. Petrie, R. Bathgate, 2013, Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia.

Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin

Zhan-Yun Guo, P. Gooley, Ashish Sethi, 2017, Scientific Reports.

The Relaxin Receptor (RXFP1) Utilizes Hydrophobic Moieties on a Signaling Surface of Its N-terminal Low Density Lipoprotein Class A Module to Mediate Receptor Activation*

P. Gooley, B. Mohanty, E. Petrie, 2013, The Journal of Biological Chemistry.

The structure of Ap(4)A hydrolase complexed with ATP-MgF(x) reveals the basis of substrate binding.

J. Fletcher, J. Swarbrick, K. Gayler, 2002, Structure.

Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius.

J. Swarbrick, K. Gayler, P. Gooley, 2001, The Biochemical journal.

The three-dimensional structure of the Nudix enzyme diadenosine tetraphosphate hydrolase from Lupinus angustifolius L.

J. Swarbrick, K. Gayler, P. Gooley, 2000, Journal of molecular biology.

Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major.

M. McConville, D. Tull, Thomas Naderer, 2012, International journal for parasitology.

Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis

M. Lew, A. Inoue, P. Gooley, 2018, iScience.

Intra- and Intersubunit Ion-Pair Interactions Determine the Ability of Apolipoprotein C-II Mutants To Form Hybrid Amyloid Fibrils.

G. Howlett, P. Gooley, I. Yarovsky, 2017, Biochemistry.

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.

G. Howlett, P. Gooley, I. Yarovsky, 2015, Biochemistry.

Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314

M. Pons, A. Inoue, P. Gooley, 2023, Nature communications.

Secondary structure in sea anemone polypeptides: a proton nuclear magnetic resonance study

R. Norton, P. Gooley, 1986 .

Specific assignment of resonances in the 1H nuclear magnetic resonance spectrum of the polypeptide cardiac stimulant anthopleurin-A.

P. Gooley, R. Norton, 1985, European journal of biochemistry.

1H nuclear magnetic resonance spectroscopic study of the polypeptide toxin I from Anemonia sulcata

R. Norton, P. Gooley, L. Béress, 1984 .

The UBA domain of SnRK1 promotes activation and maintains catalytic activity.

Monika S. Doblin, Matthew S. Gentry, M. Doblin, 2018, Biochemical and biophysical research communications.

Conformational heterogeneity in polypeptide cardiac stimulants from sea anemones

R. Norton, P. Gooley, J. Blunt, 1984, FEBS letters.

High-level expression of a soluble and functional fibronectin type II domain from MMP-2 in the Escherichia coli cytoplasm for solution NMR studies.

P. Gooley, A. Peisley, 2007, Protein expression and purification.

Applications of NMR and ITC for the Study of the Kinetics of Carbohydrate Binding by AMPK β-Subunit Carbohydrate-Binding Modules.

P. Gooley, J. Mobbs, A. Koay, 2018, Methods in molecular biology.

Preferred conformational state of the N‐terminus section of a bovine growth hormone fragment (residues 96‐133) in water is an omega loop

P. Gooley, N. Mackenzie, P. Fagerness, 1988, Proteins.

Automated NMR relaxation dispersion data analysis using NESSY

Michael Bieri, Paul R. Gooley, P. Gooley, 2011, BMC Bioinformatics.

A high‐resolution solution structure of a trypanosomatid FYVE domain

H. Mertens, M. McConville, J. Swarbrick, 2007, Protein science : a publication of the Protein Society.

Encounter complexes between the N-terminal of neurotensin with the extracellular loop 2 of the neurotensin receptor 1 steer neurotensin to the orthosteric binding pocket.

P. Gooley, Kazem Asadollahi, D. Scott, 2023, Journal of Molecular Biology.

High yield expression and purification of full-length Neurotensin with pyroglutamate modification.

P. Gooley, Kazem Asadollahi, D. Scott, 2022, Protein expression and purification.

Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1.

Monika S. Doblin, A. Bacic, D. Stapleton, 2016, Trends in plant science.

Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

B. Kemp, S. Jørgensen, D. Stapleton, 2008, Chemistry & biology.

NMR structure of human apolipoprotein C-II in the presence of sodium dodecyl sulfate.

G. Howlett, P. Gooley, D. Hatters, 2001, Biochemistry.

Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant

C. Morton, P. Gooley, K. Aizel, 2023, Nature communications.

Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation.

J. Wade, P. Gooley, E. Petrie, 2014, Biochemistry.

1H nuclear magnetic resonance spectroscopic study of the polypeptide toxin I from Anemonia sulcata

R. Norton, P. Gooley, L. Béress, 1984 .

Unravelling the mechanism of neurotensin recognition by neurotensin receptor 1

T. Weikl, P. Gooley, S. Nie, 2023, Nature communications.

Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface.

Md. Alamgir Hossain, G. Moseley, K. G. Lieu, 2019, Cell reports.

RNA Binding Properties of SOX Family Members

J. Forwood, P. Gooley, Mohammad Tanipour, 2024, Cells.

Conformation of MeAla6-cyclosporin A by NMR. Relationship of sidechain orientation of the MeBmt-1, MeLeu-9, and MeLeu-10 residues to immunosuppressive activity.

P. Gooley, J. Boger, I. Armitage, 2009, International journal of peptide and protein research.

Noncovalent Peptide Stapling Using Alpha-Methyl-l-Phenylalanine for α-Helical Peptidomimetics.

R. Dhingra, K. Rosengren, P. Gooley, 2023, Journal of the American Chemical Society.

1H, 15N and 13C resonance assignments of the C-terminal domain of the P protein of the Nishigahara strain of rabies virus

Md. Alamgir Hossain, G. Moseley, P. Gooley, 2018, Biomolecular NMR Assignments.

In vitro B cell experiments explore the role of CD24, CD38, and energy metabolism in ME/CFS

P. Gooley, G. Cambridge, C. W. Armstrong, 2024, Frontiers in immunology.

Tadpole-like conformations of huntingtin exon 1 with expanded polyglutamine engenders novel interactions in cells

R. Pappu, A. Purcell, A. Fox, 2017, bioRxiv.