B. Yachnin

发表

Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance*

Joelle N Pelletier, Jordan P Volpato, E. Fossati, 2009, The Journal of Biological Chemistry.

The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation

A. Berghuis, B. Yachnin, P. Lau, 2012, Journal of the American Chemical Society.

Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues

J. Pelletier, A. Berghuis, J. Toulouse, 2019, ACS omega.

Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme

S. Khare, B. Yachnin, 2017, Protein engineering, design & selection : PEDS.

Lactone-bound structures of cyclohexanone monooxygenase provide insight into the stereochemistry of catalysis.

A. Berghuis, B. Yachnin, K. Morley, 2014, ACS chemical biology.

Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure.

Jordan P Volpato, J. Pelletier, A. Berghuis, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5′ leader regions

N. Sonenberg, R. Cencic, J. Pelletier, 2020, Nucleic acids research.

Characterization of the redox and metal binding activity of BsSco, a protein implicated in the assembly of cytochrome c oxidase.

B. Yachnin, B. Hill, Katherine C. Yam, 2005, Biochemistry.

Massively parallel, computationally guided design of a proenzyme

S. Khare, Laura R. Azouz, J. Drake, 2022, bioRxiv.

MHCEpitopeEnergy, a Flexible Rosetta-Based Biotherapeutic Deimmunization Platform

Chris Bailey-Kellogg, Vikram Khipple Mulligan, Sagar D. Khare, 2021, J. Chem. Inf. Model..

Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor.

A. Berghuis, B. Yachnin, A. Imura, 2009, Journal of the American Chemical Society.

Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme

A. Berghuis, D. Burk, B. Yachnin, 2016, The FEBS journal.

A Bis(imidazole)-based cysteine labeling tool for metalloprotein assembly.

S. Khare, T. Emge, W. A. Hansen, 2023, Journal of inorganic biochemistry.

The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure.

A. Berghuis, B. Yachnin, P. Lau, 2016, Biochimica et biophysica acta.

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Jason W. Labonte, Jeffrey J. Gray, Johanna K. S. Tiemann, 2021, Nature Communications.