E. Turlizzi

发表

Fragmenting the S100B–p53 Interaction: Combined Virtual/Biophysical Screening Approaches to Identify Ligands

S. Mangani, D. Lalli, P. Turano, 2010, ChemMedChem.

Structure-activity relationship and properties optimization of a series of quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway.

E. Turlizzi, Arianna Nencini, M. Andreini, 2015, European journal of medicinal chemistry.

Bcl-2 down modulation in WEHI-3B/CTRES cells resistant to Cholera Toxin (CT)-induced apoptosis

E. Turlizzi, L. Cavicchini, A. Pessina, 2006, Cell Research.

Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood–Brain Barrier

E. Turlizzi, G. Oliveri, U. Zanelli, 2011, Front. Psychiatry.

Clearance-dependent underprediction of in vivo intrinsic clearance from human hepatocytes: comparison with permeabilities from artificial membrane (PAMPA) assay, in silico and caco-2 assay, for 65 drugs.

J. Houston, D. Hallifax, E. Turlizzi, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy.

M. Bolognesi, M. Marizzoni, F. Vasile, 2009, Bioorganic & medicinal chemistry.

In Vitro Toxicity of Clozapine, Olanzapine, and Quetiapine on Granulocyte-Macrophage Progenitors (GM-CFU)

E. Turlizzi, L. Cavicchini, A. Pessina, 2006 .

Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789).

T. Comery, G. Gaviraghi, E. Turlizzi, 2012, Journal of medicinal chemistry.

N-[5-(5-fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): a medicinal chemistry effort toward an α7 nicotinic acetylcholine receptor agonist preclinical candidate.

T. Comery, E. Turlizzi, Arianna Nencini, 2012, Journal of medicinal chemistry.

Comparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 Drugs

Ugo Zanelli, J. Houston, D. Hallifax, 2012, Drug Metabolism and Disposition.

An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.

M. Monshouwer, E. Turlizzi, P. Grossi, 2005, Toxicology.

Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).

T. Comery, K. Marquis, S. Grauer, 2010, Journal of medicinal chemistry.

Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor.

T. Comery, E. Turlizzi, Arianna Nencini, 2014, European journal of medicinal chemistry.

T. Comery, K. Marquis, S. Grauer, 2010, Journal of medicinal chemistry.