Cecilia Bossa

发表

Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays

Alessandro Giuliani, Olga Tcheremenskaia, Romualdo Benigni, 2010, Expert opinion on drug metabolism & toxicology.

Nongenotoxic carcinogenicity of chemicals: mechanisms of action and early recognition through a new set of structural alerts.

R. Benigni, Cecilia Bossa, O. Tcheremenskaia, 2013, Chemical reviews.

Molecular dynamics simulation of sperm whale myoglobin: effects of mutations and trapped CO on the structure and dynamics of cavities.

M. Brunori, B. Vallone, A. Amadei, 2005, Biophysical journal.

Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology.

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2011, Chemical reviews.

Entropic criteria for protein folding derived from recurrences: Six residues patch as the basic protein word

Gek Huey Chua, A. Giuliani, J. Zbilut, 2006, FEBS letters.

Predictivity and Reliability of QSAR Models: The Case of Mutagens and Carcinogens

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2008, Toxicology mechanisms and methods.

A comparative survey of chemistry-driven in silico methods to identify hazardous substances under REACH.

Emilio Benfenati, Silke Gabbert, Ralph Kühne, 2013, Regulatory toxicology and pharmacology : RTP.

In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis.

Olga Tcheremenskaia, Romualdo Benigni, Cecilia Bossa, 2013, Mutagenesis.

A data-based exploration of the adverse outcome pathway for skin sensitization points to the necessary requirements for its prediction with alternative methods.

R. Benigni, Cecilia Bossa, O. Tcheremenskaia, 2016, Regulatory toxicology and pharmacology : RTP.

DNA Damage and Repair in Human Cancer: Molecular Mechanisms and Contribution to Therapy-Related Leukemias

M. Bignami, Cecilia Bossa, I. Casorelli, 2012, International journal of environmental research and public health.

Predictivity of QSAR

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2008, J. Chem. Inf. Model..

Exploring In Vitro/In Vivo Correlation: Lessons Learned from Analyzing Phase I Results of the US EPA's ToxCast Project

A. Giuliani, R. Benigni, Cecilia Bossa, 2010, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Endocrine Disruptors: Data‐based survey of in vivo tests, predictive models and the Adverse Outcome Pathway

A. Giuliani, R. Benigni, Cecilia Bossa, 2017, Regulatory toxicology and pharmacology : RTP.

FAIRification of nanosafety data to improve applicability of (Q)SAR approaches: A case study on in vitro Comet assay genotoxicity data

Cecilia Bossa, F. Barone, C. Battistelli, 2021, Computational toxicology.

Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded project.

Alessandro Giuliani, Olga Tcheremenskaia, Romualdo Benigni, 2020, Regulatory toxicology and pharmacology : RTP.

Alessandro Giuliani, Olga Tcheremenskaia, Romualdo Benigni, 2019, EFSA Supporting Publications.

Mechanistic QSAR of aromatic amines: New models for discriminating between homocyclic mutagens and nonmutagens, and validation of models for carcinogens

Romualdo Benigni, Cecilia Bossa, Andrea Rodomonte, 2007, Environmental and molecular mutagenesis.

Formation and Repair of Mismatches Containing Ribonucleotides and Oxidized Bases at Repeated DNA Sequences*

M. Bignami, F. Mazzei, Cecilia Bossa, 2015, The Journal of Biological Chemistry.

The Benigni / Bossa rulebase for mutagenicity and carcinogenicity - a module of Toxtree

Romualdo Benigni, Nina Jeliazkova, Andrew P. Worth, 2008 .

Alternative Toxicity Testing: Analyses on Skin Sensitization, ToxCast Phases I and II, and Carcinogenicity Provide Indications on How to Model Mechanisms Linked to Adverse Outcome Pathways

Alessandro Giuliani, Olga Tcheremenskaia, Romualdo Benigni, 2015, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

The Syrian hamster embryo cells transformation assay identifies efficiently nongenotoxic carcinogens, and can contribute to alternative, integrated testing strategies.

Alessandro Giuliani, Olga Tcheremenskaia, Romualdo Benigni, 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

IARC classes 1 and 2 carcinogens are successfully identified by an alternative strategy that detects DNA-reactivity and cell transformation ability of chemicals.

Olga Tcheremenskaia, Romualdo Benigni, Cecilia Bossa, 2013, Mutation research.

Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays.

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2011, Mutagenesis.

Nanomaterial grouping: Existing approaches and future recommendations

Andrea Haase, Blanca Suarez-Merino, Nicklas Raun Jacobsen, 2019, NanoImpact.

Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.

A. Albertini, M. Bignami, F. Mazzei, 2010, DNA repair.

Conformational fluctuations and electronic properties in myoglobin

Massimiliano Aschi, Andrea Amadei, Costantino Zazza, 2004, J. Comput. Chem..

Selective excitation of native fluctuations during thermal unfolding simulations: horse heart cytochrome c as a case study.

M. Ceruso, I. Daidone, Cecilia Bossa, 2003, Biophysical journal.

The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies.

Olga Tcheremenskaia, Romualdo Benigni, Cecilia Bossa, 2012, Mutagenesis.

Improvement of quantitative structure–activity relationship (QSAR) tools for predicting Ames mutagenicity: outcomes of the Ames/QSAR International Challenge Project

Alessandro Giuliani, Emilio Benfenati, Ulf Norinder, 2018, Mutagenesis.

Structural analysis and predictive value of the rodent in vivo micronucleus assay results.

Andrew Worth, Romualdo Benigni, Cecilia Bossa, 2010, Mutagenesis.

Towards FAIR nanosafety data

Isabel Rodríguez Llopis, T. Puzyn, N. Jacobsen, 2021, Nature Nanotechnology.

In silico approaches for prediction of genotoxic and carcinogenic potential of cosmetic ingredients

A. Giuliani, R. Benigni, Cecilia Bossa, 2019, Computational Toxicology.

A topologically related singularity suggests a maximum preferred size for protein domains

Alessandro Giuliani, Kristian Rother, Arun Krishnan, 2006, Proteins.

Structure alerts for carcinogenicity, and the Salmonella assay system: a novel insight through the chemical relational databases technology.

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2008, Mutation research.

Extended molecular dynamics simulation of the carbon monoxide migration in sperm whale myoglobin.

Andrea Amadei, Cecilia Bossa, Danilo Roccatano, 2004, Biophysical journal.

Structural Alerts of Mutagens and Carcinogens

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2006 .

Dynamical Aspects of TEM-1 β-Lactamase Probed by Molecular Dynamics

Massimiliano Aschi, Cecilia Bossa, Alfredo Di Nola, 2005, J. Comput. Aided Mol. Des..

Structure-activity models of chemical carcinogens: state of the art, and new directions.

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2006, Annali dell'Istituto superiore di sanita.

(Q)SAR Methods for Predicting Genotoxicity and Carcinogenicity: Scientific Rationale and Regulatory Frameworks.

Olga Tcheremenskaia, Romualdo Benigni, Cecilia Bossa, 2018, Methods in molecular biology.

Collection and Evaluation of (Q)SAR Models for Mutagenicity and Carcinogenicity

Romualdo Benigni, Cecilia Bossa, Andrew P. Worth, 2007 .

QSARs of aromatic amines: identification of potent carcinogens.

Romualdo Benigni, Cecilia Bossa, Rainer Franke, 2010, Mutation research.

Assessment and Validation of US EPA's OncoLogic® Expert System and Analysis of Its Modulating Factors for Structural Alerts

Romualdo Benigni, Cecilia Bossa, Mauro Colafranceschi, 2012, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Dynamical aspects of TEM-1 beta-lactamase probed by molecular dynamics.

Massimiliano Aschi, Cecilia Bossa, Gianluca Sbardella, 2005, Journal of computer-aided molecular design.

Flexible use of qsar models in predictive toxicology: A case study on aromatic amines

Romualdo Benigni, Cecilia Bossa, R. Benigni, 2012, Environmental and molecular mutagenesis.

New perspectives in toxicological information management, and the role of ISSTOX databases in assessing chemical mutagenicity and carcinogenicity.

Olga Tcheremenskaia, Romualdo Benigni, Cecilia Bossa, 2013, Mutagenesis.

The Expanding Role of Predictive Toxicology: An Update on the (Q)SAR Models for Mutagens and Carcinogens

Emilio Benfenati, Romualdo Benigni, Chihae Yang, 2007, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Structural analysis and predictive value of the rodent in vivo micronucleus assay results.

R. Benigni, Cecilia Bossa, Andrew Paul Worth, 2010, Mutagenesis.

Assessment and Validation of US EPA's OncoLogic® Expert System and Analysis of Its Modulating Factors for Structural Alerts

R. Benigni, Cecilia Bossa, M. Colafranceschi, 2012, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.