Peter D Gibbons

发表

Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity.

J. Gut, P. Rosenthal, R. Guedes, 2010, Journal of medicinal chemistry.

Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis.

G. Aljayyoussi, Peter D Gibbons, G. Nixon, 2017, Journal of medicinal chemistry.

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

J. Hemingway, R. Sinden, M. Delves, 2012, Proceedings of the National Academy of Sciences.

Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)

Peter D Gibbons, G. Nixon, R. Amewu, 2012, Journal of medicinal chemistry.

Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.

Peter D Gibbons, R. Amewu, P. Stocks, 2008, Journal of medicinal chemistry.

A novel drug for uncomplicated malaria: targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNdh2) of Plasmodium falciparum

Peter D Gibbons, V. Barton, G. Nixon, 2010, Malaria Journal.

Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.

C. Davis, B. K. Park, Peter D Gibbons, 2009, Journal of medicinal chemistry.

Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.

J. Gut, P. Rosenthal, Peter D Gibbons, 2008, Bioorganic & medicinal chemistry letters.

2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties

Peter D Gibbons, G. Nixon, G. Biagini, 2015 .

Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols.

J. Bacsa, Peter D Gibbons, G. Nixon, 2010, Organic & biomolecular chemistry.

Alpha-lithio quinuclidine N-oxide (Li-QNO): a new base for synthetic chemistry.

Peter D Gibbons, I. O'neil, I. Bhamra, 2006, Chemical communications.

Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)

Peter D Gibbons, G. Nixon, R. Amewu, 2012, Journal of medicinal chemistry.

Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs.

Ruth H. Hughes, Peter D Gibbons, V. Barton, 2007, Angewandte Chemie.

Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods

Paul Stocks, Paul M. O'Neill, Neil G. Berry, 2012, Journal of medicinal chemistry.

Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis.

G. Aljayyoussi, Peter D Gibbons, G. Nixon, 2017, Journal of medicinal chemistry.