B. Debrus

发表

Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments, independent component analysis and design space.

E. Rozet, B. Debrus, Ph. Hubert, 2011, Journal of chromatography. A.

Predictive elution window stretching and shifting as a generic search strategy for automated method development for liquid chromatography.

S. Rudaz, D. Guillarme, D. Clicq, 2012, Analytical chemistry.

Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography.

S. Rudaz, D. Guillarme, B. Debrus, 2013, Journal of pharmaceutical and biomedical analysis.

Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography.

Benjamin Debrus, Philippe Hubert, Bruno Boulanger, 2011, Analytica chimica acta.

Application of an innovative design space optimization strategy to the development of liquid chromatographic methods to combat potentially counterfeit nonsteroidal anti-inflammatory drugs.

T. Schofield, R. Marini, P. Hubert, 2012, Journal of chromatography. A.

Application of a new optimization strategy for the separation of tertiary alkaloids extracted from Strychnos usambarensis leaves.

L. Angenot, P. Hubert, E. Rozet, 2011, Journal of pharmaceutical and biomedical analysis.

A new statistical method for the automated detection of peaks in UV-DAD chromatograms of a sample mixture.

Benjamin Debrus, Philippe Hubert, Bruno Boulanger, 2009, Talanta.

Comprehensive profiling and marker identification in non-volatile citrus oil residues by mass spectrometry and nuclear magnetic resonance.

S. Rudaz, L. Marcourt, J. Boccard, 2014, Food chemistry.

Retention time prediction for dereplication of natural products (CxHyOz) in LC-MS metabolite profiling.

P. Carrupt, J. Boccard, Philippe J. Eugster, 2014, Phytochemistry.

Software-Assisted Method Development in High Performance Liquid Chromatography

Benjamin Debrus, Pierre Lebrun, Serge Rudaz, 2018 .

Screening of the most relevant parameters for method development in ultra-high performance hydrophilic interaction chromatography.

S. Rudaz, A. Periat, D. Guillarme, 2013, Journal of chromatography. A.

Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach.

S. Rudaz, M. Velazco, J. Boccard, 2014, Food chemistry.

Study of the physicochemical properties in aqueous medium and molecular modeling of tagitinin C/cyclodextrin complexes.

L. Angenot, G. Dive, L. Delattre, 2007, Journal of pharmaceutical and biomedical analysis.

Design Spaces for analytical methods

Benjamin Debrus, Philippe Hubert, Bruno Boulanger, 2013 .

Chapter 3:Method Transfer Between Conventional HPLC and UHPLC

Benjamin Debrus, Serge Rudaz, Philippe Hubert, 2012 .

Validation, transfer and measurement uncertainty estimation of an HPLC-UV method for the quantification of artemisinin in hydro alcoholic extracts of Artemisia annua L.

P. Hubert, E. Rozet, B. Evrard, 2011, Journal of pharmaceutical and biomedical analysis.

Development of a generic micellar electrokinetic chromatography method for the separation of 15 antimalarial drugs as a tool to detect medicine counterfeiting

Pierre Lebrun, A. Servais, P. Hubert, 2012, Electrophoresis.

Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities.

Benjamin Debrus, Eric Ziemons, Philippe Hubert, 2011, Journal of pharmaceutical and biomedical analysis.

Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material.

Benjamin Debrus, Philippe Hubert, Pierre Lebrun, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development of a nano-liquid chromatography on chip tandem mass spectrometry method for high-sensitivity hepcidin quantitation.

M. Fillet, B. Debrus, F. Lecomte, 2011, Journal of chromatography. A.

Study of common database feeding with results coming from different analytical methods in the framework of illicit drugs chemical profiling.

Benjamin Debrus, Serge Rudaz, Julian Broséus, 2013, Forensic science international.

CE‐MS method development for peptides analysis, especially hepcidin, an iron metabolism marker

A. Servais, P. Hubert, E. Rozet, 2009, Electrophoresis.

Rational and Efficient Preparative Isolation of Natural Products by MPLC-UV-ELSD based on HPLC to MPLC Gradient Transfer

D. Guillarme, J. Wolfender, B. Debrus, 2015, Planta Medica.

Development of a new predictive modelling technique to find with confidence equivalence zone and design space of chromatographic analytical methods

Benjamin Debrus, Philippe Hubert, Bruno Boulanger, 2008 .

Validated quantitative simultaneous determination of cocaine, opiates and amphetamines in serum by UHPLC-MS/MS

P. Hubert, C. Charlier, B. Debrus, 2010 .

New methodology for the development of chromatographic methods with bioanalytical application.

Benjamin Debrus, Philippe Hubert, Pierre Lebrun, 2011, Bioanalysis.

Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material.

Pierre Lebrun, A. Verstraete, P. Hubert, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A Bayesian Design Space for Analytical Methods Based on Multivariate Models and Predictions

Benjamin Debrus, Pierre Lebrun, Bruno Boulanger, 2013, Journal of biopharmaceutical statistics.

Method Transfer Between Conventional HPLC and UHPLC

Benjamin Debrus, Serge Rudaz, Philippe Hubert, 2012 .

A New Method for Quality by Design Robust Optimization in Liquid Chromatography

Roland Marini Djang'Eing'A, Jérémie Mbinze Kindenge, Benjamin Debrus, 2013 .

Application of design of experiments and design space methodology for the HPLC-UV separation optimization of aporphine alkaloids from leaves of Spirospermum penduliflorum Thouars.

Benjamin Debrus, Philippe Hubert, Pierre Lebrun, 2012, Journal of pharmaceutical and biomedical analysis.