A. Chubb

发表

Title CycloPs : generating virtual libraries of cyclized andconstrained peptides including nonnatural amino acids

D. Shields, F. J. Du, E. Vernière, 2018 .

Cyclooxygenase‐1 haplotype modulates platelet response to aspirin

A. Maree, D. Shields, D. Fitzgerald, 2005, Journal of thrombosis and haemostasis : JTH.

Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis

S. Gordon, K. Malone, A. Chubb, 2016, Microbial genomics.

The productive conformation of prostaglandin G2 at the peroxidase site of prostaglandin endoperoxide H synthase: docking, molecular dynamics, and site-directed mutagenesis studies.

D. Fitzgerald, A. Chubb, K. Nolan, 2006, Biochemistry.

Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data

Heinrich C. Hoppe, David Toomey, Anthony J. Chubb, 2009, PloS one.

Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer

C. Oxvig, Y. Smith, G. Kirwan, 2018, BMC Cancer.

Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer

C. Oxvig, Y. Smith, G. Kirwan, 2018, BMC Cancer.

Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation

Alessandro, Serge, Tyler B. Hughes, 2016 .

Cleavage of disulfide-bridged stalk domains during shedding of angiotensin-converting enzyme occurs at multiple juxtamembrane sites.

E. Sturrock, L. Yan, A. Chubb, 2001, Biochemistry.

RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin alpha(IIb)beta3.

N. Moran, A. Chubb, A. Treumann, 2008, Biochemical and biophysical research communications.

Proteolytic release of membrane proteins: studies on a membrane-protein-solubilizing activity in CHO cells.

J. Riordan, A. Chubb, R. Scholle, 1997, Immunopharmacology.

Identification of Mycobacterium tuberculosis signal sequences that direct the export of a leaderless beta-lactamase gene product in Escherichia coli.

A. Chubb, H. Hoffmann, R. Scholle, 1998, Microbiology.

ldentif ication of Mycobacterium tuberculosis signal sequences that direct the export of a leaderless P4actamase gene product in

A. Chubb, R. Scholle, M. Ehlers, 1998 .

C‐reactive protein binds to αIIbβ3

M. Brennan, A. Chubb, R. Moriarty, 2008, Journal of thrombosis and haemostasis : JTH.

Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain.

E. Sturrock, A. Chubb, S. Schwager, 2002, Biochemical and biophysical research communications.

Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding

N. Hooper, E. Sturrock, A. Chubb, 2001 .

Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding.

N. Hooper, E. Sturrock, A. Chubb, 2001, The Biochemical journal.

Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activity.

Mauro F. A. Adamo, A. Chubb, Ahmed Alagha, 2009, Bioorganic & medicinal chemistry letters.

C-reactive protein binds to alphaIIbbeta 3

M. Brennan, A. Chubb, R. Moriarty, 2015 .

Modulation of juxtamembrane cleavage ("shedding") of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease.

E. Sturrock, J. Riordan, A. Chubb, 1999, Biochemistry.

Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties

E. Sturrock, A. Chubb, E. L. van der Merwe, 2006, Biological chemistry.

Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding H1 RNA, the RNA component of human RNase P.

G. Hannon, T. Nilsen, S. Altman, 1991, The Journal of biological chemistry.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Manuel Llinás, George Papadatos, Sundari Suresh, 2016, PLoS pathogens.

Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity.

D. Fitzgerald, M. Devocelle, A. Chubb, 2005, Organic & biomolecular chemistry.

A genome‐wide association study of recipient genotype and medium‐term kidney allograft function

Sean Ennis, Carol Traynor, Mark McCormack, 2013, Clinical transplantation.

A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity.

M. Morgan, M. Brennan, A. Chubb, 2013, Journal of inorganic biochemistry.

Immunophilins as Possible Drug Targets in Apicomplexan Parasites

A. Bell, A. Chubb, A. Bianchin, 2016 .

CycloPs: Generating Virtual Libraries of Cyclized and Constrained Peptides Including Nonnatural Amino Acids

Marc Devocelle, Denis C. Shields, Fergal J. Duffy, 2011, J. Chem. Inf. Model..

TIN - A Combinatorial Compound Collection of Synthetically Feasible Multicomponent Synthesis Products

Tim Heinemann, Dermot Cox, David Toomey, 2011, J. Chem. Inf. Model..

BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer

D. Matallanas, E. Kay, A. McCann, 2018, Oncotarget.

Deletion of the cytoplasmic domain increases basal shedding of angiotensin-converting enzyme.

E. Sturrock, A. Chubb, E. L. van der Merwe, 2004, Biochemical and Biophysical Research Communications - BBRC.

Design and Evaluation of Antimalarial Peptides Derived from Prediction of Short Linear Motifs in Proteins Related to Erythrocyte Invasion

A. Bell, D. Shields, A. Chubb, 2015, PloS one.

Phorbol ester-induced juxtamembrane cleavage of angiotensin-converting enzyme is not inhibited by a stalk containing intrachain disulfides.

E. Sturrock, C. Eckerskorn, A. Chubb, 1998, Biochemistry.

Two crystal structures of the FK506-binding domain of Plasmodium falciparum FKBP35 in complex with rapamycin at high resolution.

A. Bell, A. Chubb, F. Allemand, 2015, Acta crystallographica. Section D, Biological crystallography.

Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer

C. Oxvig, Y. Smith, G. Kirwan, 2018, BMC Cancer.

Elucidating the role of Staphylococcus epidermidis serine–aspartate repeat protein G in platelet activation

T. Foster, D. Cox, M. Brennan, 2009, Journal of thrombosis and haemostasis : JTH.

BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer

D. Matallanas, E. Kay, A. McCann, 2018, Oncotarget.