Mingli Xiang

发表

Virtual screening in small molecule discovery for epigenetic targets.

Yu Cao, Jun Zou, R. Xiang, 2015, Methods.

Bio-inspired detoxification using 3D-printed hydrogel nanocomposites

Wei Zhu, Yuquan Wei, Kang Zhang, 2014, Nature Communications.

Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.

X. Liang, Mingli Xiang, Liang Ma, 2013, European journal of medicinal chemistry.

Correlation between biological activity and binding energy in systems of integrin with cyclic RGD-containing binders: a QM/MM molecular dynamics study

Y. Mo, Yuchun Lin, Sheng-yong Yang, 2012, Journal of Molecular Modeling.

In silico identification of EGFR-T790M inhibitors with novel scaffolds: start with extraction of common features

Y. Mo, Yuchun Lin, Gu He, 2013, Drug design, development and therapy.

Improving the anti-ovarian cancer activity of docetaxel with biodegradable self-assembly micelles through various evaluations.

Yuquan Wei, Z. Qian, G. Guo, 2015, Biomaterials.

Simultaneous removal of ammonium and nitrate by HDTMA-modified zeolite.

Tian C. Zhang, Cheng Li, Mingli Xiang, 2015, Water science and technology : a journal of the International Association on Water Pollution Research.

Synthesis and biological evaluation of 4-oxoquinoline-3-carboxamides derivatives as potent anti-fibrosis agents.

Yuquan Wei, Mingli Xiang, Liang Ma, 2014, Bioorganic & medicinal chemistry letters.

Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach

Yiming Yuan, Mingli Xiang, Li-juan Chen, 2014, Molecular Diversity.

Synthesis, structure-activity relationships and biological evaluation of barbigerone analogues as anti-proliferative and anti-angiogenesis agents.

Yuquan Wei, F. Wang, Mingli Xiang, 2014, Bioorganic & medicinal chemistry letters.

Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.

Yuquan Wei, X. Liang, F. Wang, 2014, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel millepachine derivatives as a new class of tubulin polymerization inhibitors.

Mingli Xiang, F. Wang, Liang Ma, 2014, Journal of medicinal chemistry.

Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis

Sheng-yong Yang, Mingli Xiang, Zhuang Yang, 2018, Scientific Reports.

Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice

Yuquan Wei, Mingli Xiang, Liang Ma, 2015, Molecular diversity.

SKLB023 Blocks Joint Inflammation and Cartilage Destruction in Arthritis Models via Suppression of Nuclear Factor-Kappa B Activation in Macrophage

Mingli Xiang, Liang Ma, Heying Pei, 2013, PloS one.

First-principles study of the adsorption of lysine on hydroxyapatite (1 0 0) surface

D. He, Xing‐dong Zhang, H. Fan, 2012 .

Design, synthesis and evaluation of novel 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as potent, selective and reversible Bruton's tyrosine kinase (BTK) inhibitors for the treatment of rheumatoid arthritis.

Mingli Xiang, Heying Pei, Lijuan Chen, 2019, European journal of medicinal chemistry.

Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia.

Yuquan Wei, Sheng-yong Yang, Mingli Xiang, 2019, Journal of Medicinal Chemistry.

Applying an innovative biodegradable self-assembly nanomicelles to deliver α-mangostin for improving anti-melanoma activity

Yuzhu Hu, Mingli Xiang, Xiang Gao, 2019, Cell Death & Disease.

Synthesis and biological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives for the treatment of inflammatory diseases.

Yuquan Wei, Tao Chen, X. Liang, 2011, Journal of medicinal chemistry.

Discovery of Potent and Orally Effective Dual JAK2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms.

Mingli Xiang, Zhuang Yang, Ming-hai Tang, 2019, Journal of medicinal chemistry.

Calcium phosphate embedded PLGA nanoparticles: a promising gene delivery vector with high gene loading and transfection efficiency.

Jie Tang, A. Tong, Xiangrong Song, 2012, International journal of pharmaceutics.

Synthesis of novel spirooxindolo-pyrrolidines, pyrrolizidines, and pyrrolothiazoles via a regioselective three-component [3+2] cycloaddition and their preliminary antimicrobial evaluation

L. Ouyang, Shi Zeng, Gu He, 2013, Molecular Diversity.

Synthesis of novel spirooxindolo-pyrrolidines, pyrrolizidines, and pyrrolothiazoles via a regioselective three-component [3+2] cycloaddition and their preliminary antimicrobial evaluation

L. Ouyang, Shi Zeng, Gu He, 2013, Molecular Diversity.

Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases.

X. Liang, Mingli Xiang, Liang Ma, 2015, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes.

Yuquan Wei, Tao Chen, X. Liang, 2012, European journal of medicinal chemistry.

Simultaneous removal of nitrogen and phosphorus by cetylpyridinium bromide modified zeolite.

Tian C. Zhang, Cheng Li, Mingli Xiang, 2017, Water science and technology : a journal of the International Association on Water Pollution Research.

Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles.

Ling Li, Lu Sun, Qinjie Wu, 2013, Biomaterials.

Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents.

Yuquan Wei, X. Liang, Mingli Xiang, 2012, European journal of medicinal chemistry.

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms".

Mingli Xiang, Zhuang Yang, Ming-hai Tang, 2020, Journal of medicinal chemistry.

Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles

Tao Chen, Mingli Xiang, Lulu Cai, 2013, International journal of nanomedicine.

B7 family protein glycosylation: Promising novel targets in tumor treatment

Mingli Xiang, Chengcheng Liao, Xiaoyan Guan, 2022, Frontiers in Immunology.

Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo.

Xia Zhao, MaLing Gou, ZhiYong Qian, 2011, Nanoscale.

Discovery of Novel Focal Adhesion Kinase Inhibitors Using a Hybrid Protocol of Virtual Screening Approach Based on Multicomplex-Based Pharmacophore and Molecular Docking

Cheng Peng, Ting Xu, Liang Ouyang, 2012, International journal of molecular sciences.

Self‐Assembled Bifunctional Peptide as Effective Drug Delivery Vector with Powerful Antitumor Activity

Yuquan Wei, Z. Qian, Lan Mei, 2017, Advanced science.

Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma.

Qinjie Wu, Yuquan Wei, C. Gong, 2012, Nanoscale.

Powerful anti-colon cancer effect of modified nanoparticle-mediated IL-15 immunogene therapy through activation of the host immune system

Yuquan Wei, Yuzhu Hu, G. Guo, 2018, Theranostics.

Computer-aided drug design: lead discovery and optimization.

Yu Cao, Wenjie Fan, Yirong Mo, 2012, Combinatorial chemistry & high throughput screening.

Which polymer is more suitable for etoposide: A comparison between two kinds of drug loaded polymeric micelles in vitro and in vivo?

Yuquan Wei, Z. Qian, Jun Li, 2015, International journal of pharmaceutics.

Applying an innovative biodegradable self-assembly nanomicelles to deliver α-mangostin for improving anti-melanoma activity

Yuzhu Hu, Mingli Xiang, Xiang Gao, 2019, Cell Death & Disease.

A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance.

Mingli Xiang, Liang Ma, Li-juan Chen, 2011, European journal of pharmacology.

Synthesis and biological evaluation of pyranoisoflavone derivatives as anti-inflammatory agents.

Yuquan Wei, Mingli Xiang, Liang Ma, 2014, Fitoterapia.

Discovery of 3-(4-(2-((1H-Indol-5-yl)amino)-5-fluoropyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile Derivatives as Selective TYK2 Inhibitors for the Treatment of Inflammatory Bowel Disease.

Mingli Xiang, Ming-hai Tang, Yong Li, 2021, Journal of medicinal chemistry.

Discovery of 4-(1,2,4-Oxadiazol-5-yl)azepan-2-one Derivatives as a New Class of Cannabinoid Type 2 Receptor Agonists for the Treatment of Inflammatory Pain.

Yifei Wang, Mingli Xiang, Xin Yang, 2023, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis.

Mingli Xiang, Heying Pei, Lijuan Chen, 2018, European journal of medicinal chemistry.

Combined structure-based pharmacophore, virtual screening, and 3D-QSAR studies of structural diverse dehydrosqualene synthase inhibitors

Gu He, Mingli Xiang, Tao Yang, 2013, Medicinal Chemistry Research.

Synthesis and biological evaluation of 5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione derivatives for the treatment of obesity-related nonalcoholic fatty liver disease.

Yuquan Wei, X. Liang, Mingli Xiang, 2012, Journal of medicinal chemistry.

N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms.

Mingli Xiang, Zhuang Yang, Ming-hai Tang, 2020, Journal of medicinal chemistry.

Combined Structure-Based Pharmacophore and 3D-QSAR Studies on Phenylalanine Series Compounds as TPH1 Inhibitors

Wei Huang, Liang Ouyang, Gu He, 2012, International journal of molecular sciences.

Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.

Yuquan Wei, Mingli Xiang, Liang Ma, 2013, Bioorganic & medicinal chemistry.

In situ gel-forming dual drug delivery system for synergistic combination therapy of colorectal peritoneal carcinomatosis

Juan Shi, Yuelong Wang, A. Tong, 2015 .

Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice

Yuquan Wei, Mingli Xiang, Liang Ma, 2015, Molecular Diversity.

Combining structure-based pharmacophore modeling, virtual screening, and in silico ADMET analysis to discover novel tetrahydro-quinoline based pyruvate kinase isozyme M2 activators with antitumor activity

Wei Huang, Cheng Peng, Liang Ouyang, 2014, Drug design, development and therapy.

Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening.

Dingguo Xu, T. Yang, Mingli Xiang, 2023, Journal of medicinal chemistry.

Molecular Modeling Study of Selective Recognition Between Imidazole Cyclophane and Amino Acid Esters

Rong Xiao, Kai Lei, Qun Zeng, 2012 .

Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach

Yiming Yuan, Mingli Xiang, Li-juan Chen, 2014, Molecular Diversity.