Soon Ha Kim

发表

Drug Signature-based Finding of Additional Clinical Use of LC28-0126 for Neutrophilic Bronchial Asthma

So Ri Kim, Yong Chul Lee, E. Shin, 2015, Scientific Reports.

NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice.

P. Vandenabeele, M. Grootaert, D. Schrijvers, 2016, Atherosclerosis.

Neuroprotective effect of NecroX-5 against retinal degeneration in rodents

Gyu Hyun Kim, Soon Ha Kim, In-Beom Kim, 2016, Neuroreport.

Pharmacokinetics and safety of a single dose of the novel necrosis inhibitor LC28‐0126 in healthy male subjects

Hyun-Jai Cho, Sang-Heon Cho, Soon Ha Kim, 2017, British Journal of Clinical Pharmacology.

Creation of myocardial fibrosis by transplantation of fibroblasts primed with survival factors.

Seil Oh, Hyun-Jai Cho, Hyo‐Soo Kim, 2011, American journal of physiology. Heart and circulatory physiology.

The Free Radical Scavenger NecroX-7 Attenuates Acute Graft-versus-Host Disease via Reciprocal Regulation of Th1/Regulatory T Cells and Inhibition of HMGB1 Release

H. Kim, Soon Ha Kim, Seok-Goo Cho, 2015, The Journal of Immunology.

An indole derivative protects against acetaminophen-induced liver injury by directly binding to N-acetyl-p-benzoquinone imine in mice.

M. Shong, S. Tadi, G. Kweon, 2013, Antioxidants & redox signaling.

NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts

V. Thu, Jin Han, B. Rhee, 2016, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Surface of Human Thymocytes TCR and MHC Class I and II Molecules on the Engagement of CD99 Induces Up-Regulation of

You Young Kim, W. Park, Soon Ha Kim, 1998 .

Activation of NLRP3 inflammasome is regulated by mitochondrial ROS via PI3K-HIF-VEGF pathway in acute lung injury

So Ri Kim, Yong Chul Lee, Soon Ha Kim, 2015 .

NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter.

V. Thu, Jin Han, B. Rhee, 2012, Cardiovascular research.

NecroX‐5 suppresses sodium nitroprusside‐induced cardiac cell death through inhibition of JNK and caspase‐3 activation

Jin Han, B. Rhee, K. Ko, 2014, Cell biology international.

NecroX as a novel class of mitochondrial reactive oxygen species and ONOO− scavenger

H. Kim, B. Ahn, Soon Ha Kim, 2010, Archives of pharmacal research.

STAT4/6-dependent differential regulation of chemokine receptors.

N. Sarvetnick, Soon Ha Kim, K. Gunst, 2006, Clinical immunology.

Airway epithelial phosphoinositide 3-kinase-δ contributes to the modulation of fungi-induced innate immune response

So Ri Kim, Yong Chul Lee, Soon Ha Kim, 2018, Thorax.

MIT-001 Restores Human Placenta-Derived Mesenchymal Stem Cells by Enhancing Mitochondrial Quiescence and Cytoskeletal Organization

Y. J. Kim, J. Ko, Soon Ha Kim, 2021, International journal of molecular sciences.

A novel small molecule, NecroX-7, inhibits osteoclast differentiation by suppressing NF-κB activity and c-Fos expression.

In-kyu Lee, Shin-Yoon Kim, Mi-Kyung Lee, 2012, Life sciences.

T Cells and Inhibition of Hmgb1 Release via Reciprocal Regulation of Th1/regulatory Attenuates Acute Graft-versus-host Disease the Free Radical Scavenger Necrox-7

Soon Ha Kim, Seok-Goo Cho, Eun-Jung Kim, 2022 .

Type 2 Nitric Oxide Synthase Control of the Autoimmune Response by

H. Ljunggren, N. Sarvetnick, Soon Ha Kim, 2001 .

Pharmacokinetics and Tolerability of LC28-0126, a Novel Necrosis Inhibitor, After Multiple Ascending Doses: A Phase I Randomized, Double-Blind, Placebo-Controlled Study in Healthy Male Subjects.

Eunwoo Kim, Myungwon Jin, Soon Ha Kim, 2020, Clinical therapeutics.

NecroX-7 prevents oxidative stress-induced cardiomyopathy by inhibition of NADPH oxidase activity in rats.

H. Kim, Ji-Hoon Park, B. Ahn, 2012, Toxicology and applied pharmacology.

HSOA Journal of Stem Cells Research, Development & Therapy Emerging Role of Mitochondrial Function Enhancement in Mesenchymal Stem Cell Therapy

Soon Ha Kim, Jeong-Hee Yang, 2022 .

The indole derivative NecroX‐7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation

H. Chung, J. Hwang, M. Shong, 2015, Liver international : official journal of the International Association for the Study of the Liver.

Control of the Autoimmune Response by Type 2 Nitric Oxide Synthase1 2

F. Shi, H. Ljunggren, N. Sarvetnick, 2001, The Journal of Immunology.

Therapeutic Potential of a Novel Necrosis Inhibitor, 7-Amino-Indole, in Myocardial Ischemia–Reperfusion Injury

Hyun-Jai Cho, Hyo‐Soo Kim, Han-Mo Yang, 2018, Hypertension.

CCR4-bearing T cells participate in autoimmune diabetes.

N. Sarvetnick, H. Fox, Soon Ha Kim, 2002, The Journal of clinical investigation.

Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

F. Shi, N. Sarvetnick, J. Strominger, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo.

R. Warrell, Soon Ha Kim, R. Gallagher, 2002, Blood.

NecroX-5 protects mitochondrial oxidative phosphorylation capacity and preserves PGC1α expression levels during hypoxia/reoxygenation injury

V. Thu, Jin Han, B. Rhee, 2016, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

The Effect of Necrosis Inhibitor on Dextran Sulfate Sodium Induced Chronic Colitis Model in Mice

Soon Ha Kim, J. Hyun, Y. Jung, 2023, Pharmaceutics.

ILK (β1-integrin-linked protein kinase): a novel immunohistochemical marker for Ewing’s sarcoma and primitive neuroectodermal tumour

M. Kook, E. Choi, Soon Ha Kim, 1998, Virchows Archiv.

NecroX-5 prevents breast cancer metastasis by AKT inhibition via reducing intracellular calcium levels.

Jin Han, Nari Kim, Soon Ha Kim, 2017, International journal of oncology.

In vitro broad-spectrum antiviral activity of MIT-001, a mitochondria-targeted reactive oxygen species scavenger, against severe acute respiratory syndrome coronavirus 2 and multiple zoonotic viruses

Junsang Yoo, Soon Ha Kim, Won-Keun Kim, 2023, bioRxiv.

Viral latent membrane protein 1 (LMP-1)-induced CD99 down-regulation in B cells leads to the generation of cells with Hodgkin's and Reed-Sternberg phenotype.

S. H. Kim, Young Ho Suh, Y. Shin, 2000, Blood.

NecroX‐5 suppresses sodium nitroprusside‐induced cardiac cell death through inhibition of JNK and caspase‐3 activation

Jin Han, B. Rhee, K. Ko, 2014, Cell biology international.

NecroX as a novel class of mitochondrial reactive oxygen species and ONOO− scavenger

H. Kim, B. Ahn, Soon Ha Kim, 2010, Archives of pharmacal research.