Rafael V. C. Guido

发表

In silico screening strategies for novel inhibitors of parasitic diseases

R. S. Ferreira, G. Oliva, A. Andricopulo, 2011, Expert opinion on drug discovery.

Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19

Rafael V. C. Guido, M. Buckeridge, G. Courtemanche, 2020, bioRxiv.

Discovery of (E)-4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist that regulates high-density lipoprotein-cholesterol levels, modulates adipogenesis, and improves glucose tolerance in diet-induced obese mice.

M. Chorilli, Rafael V. C. Guido, M. Passarelli, 2022, Bioorganic chemistry.

A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K

D. Brömme, Rafael V. C. Guido, A. Aguda, 2017, PloS one.

High-Throughput Screening Reveals New Glutaminase Inhibitor Molecules.

M. M. Dias, Rafael V. C. Guido, D. Adamoski, 2021, ACS pharmacology & translational science.

Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues

M. Meneghetti, Rafael V. C. Guido, A. Krettli, 2022, International journal for parasitology. Drugs and drug resistance.

Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika

S. Ekins, C. Andrade, E. Muratov, 2022, J. Chem. Inf. Model..

Synthesis, Structure–Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New Plasmodium falciparum Inhibitors

Rafael V. C. Guido, A. C. Aguiar, Igor M R Moura, 2022, Pharmaceuticals.

A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K

J. Delaissé, K. Søe, D. Brömme, 2016, British journal of pharmacology.

Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors

M. Juliano, G. Oliva, Rafael V. C. Guido, 2021, Molecules.

Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing N-Methyl Amino Acids as Antiplasmodial Agents.

E. Winzeler, V. Yardley, F. Gamo, 2018, ACS medicinal chemistry letters.

Discovery of aminothiazole derivatives as a chemical scaffold for glutaminase inhibition

M. P. Pinheiro, J. Pastre, Rafael V. C. Guido, 2023, Results in Chemistry.

New Isoquinoline Alkaloids from Paraphaeosphaeria sporulosa F03, a Fungal Endophyte Isolated from Paepalanthus planifolius

Rafael V. C. Guido, M. Furlan, T. Bauab, 2021, Planta Medica.

Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor.

C. Craik, D. Brömme, Rafael V. C. Guido, 2015, The Biochemical journal.

Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.

M. G. Albuquerque, M. Nonato, Rafael V. C. Guido, 2020, European journal of medicinal chemistry.

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

P. Rosenthal, M. Llinás, D. Fidock, 2021, bioRxiv.

Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome

E. Winzeler, L. Tilley, D. Fidock, 2021, Proceedings of the National Academy of Sciences.

Discovery of New Inhibitors of Schistosoma mansoni PNP by Pharmacophore-Based Virtual Screening

Marcelo Santos Castilho, Glaucius Oliva, Matheus P. Postigo, 2010, J. Chem. Inf. Model..

A pharmacophore-based virtual screening approach for the discovery of Trypanosoma cruzi GAPDH inhibitors.

Glaucius Oliva, Adriano D Andricopulo, G. Oliva, 2013, Future medicinal chemistry.

Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors.

Kimberley M. Zorn, S. Ekins, C. Andrade, 2021, Bioorganic chemistry.

A novel scaffold to fight Pseudomonas aeruginosa pyocyanin production: early steps to novel antivirulence drugs.

Rafael V. C. Guido, M. Castilho, T. Q. Froes, 2020, Future medicinal chemistry.

Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins.

Kimberley M. Zorn, Daniel H. Foil, S. Ekins, 2022, Bioorganic chemistry.

The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity

S. Valentini, Rafael V. C. Guido, M. Furlan, 2021, Molecules.

Polyketide- and Terpenoid-Derived Metabolites Produced by a Marine-Derived Fungus, Peroneutypa sp.

Rafael V. C. Guido, Laura P. Ióca, R. Berlinck, 2023, Journal of natural products.

Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria

S. Antonyuk, G. Oliva, Rafael V. C. Guido, 2021, European Journal of Medicinal Chemistry Reports.

Copper-Catalyzed Synthesis of Pyrrolo[1,2-c]quinazolines and Pyrrolo[2,1-a]isoquinolines and Antiplasmodial Evaluation.

G. Oliva, Rafael V. C. Guido, T. Opatz, 2023, The Journal of organic chemistry.

Inhibition of 3-Hydroxykynurenine Transaminase from Aedes aegypti and Anopheles gambiae: A Mosquito-Specific Target to Combat the Transmission of Arboviruses

R. Lins, T. Soares, Rafael V. C. Guido, 2023, ACS bio & med chem Au.

Editorial: Antimalarial chemotherapy in the XXIst century, volume II

Rafael V. C. Guido, P. Gomes, Rafael V. C. Guido, 2023, Frontiers in Pharmacology.

New strategies for novel drugs: antimicrobial peptides containing ferrocene with improved antifungal and antiplasmodial biological activity.

G. Oliva, Rafael V. C. Guido, E. Cilli, 2022, Protein and peptide letters.

Editorial: Antimalarial chemotherapy in the XXIst century

Rafael V. C. Guido, P. Gomes, 2022, Frontiers in Pharmacology.

Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi

Rafael V. C. Guido, C. Teles, M. S. Araújo, 2023, Scientific reports.

High-Throughput Screening Reveals New Glutaminase Inhibitor Molecules.

M. M. Dias, Rafael V. C. Guido, K. A. Gonçalves, 2021, ACS pharmacology & translational science.