D. Ludovici

发表

Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants.

H. M. Vinkers, A. D. Clark, R. Pauwels, 2004, Journal of medicinal chemistry.

Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues.

R. Pauwels, E. Arnold, F. Daeyaert, 2001, Bioorganic & medicinal chemistry letters.

TMC125, a Novel Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor Active against Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Human Immunodeficiency Virus Type 1

Koen Andries, Hilde Azijn, Theo Thielemans, 2004, Antimicrobial Agents and Chemotherapy.

In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).

Stephen H Hughes, Peter Williams, Paul J Lewi, 2005, Journal of medicinal chemistry.

Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU).

R. Pauwels, E. Arnold, P. Janssen, 2001, Bioorganic & medicinal chemistry letters.

Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy.

Tianbao Lu, G. Bignan, M. Cummings, 2018, Bioorganic & medicinal chemistry letters.

Abstract 801: Sensitivity of cell lines to Fatty Acid Synthase inhibitors depends on the lipid content in the cellular environment

Yolanda T. Chong, Tianbao Lu, G. Bignan, 2014 .

(6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: platelet-derived growth factor receptor tyrosine kinase inhibitors with broad antiproliferative activity against tumor cells.

Jian Li, Judith Baker, Hong-tao Lu, 2005, Journal of medicinal chemistry.

Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo [4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 3.

M. Miranda, T. Hitchens, G. Leo, 1991, Journal of medicinal chemistry.

Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues.

R. Pauwels, E. Arnold, F. Daeyaert, 2001, Bioorganic & medicinal chemistry letters.

Evolution of anti-HIV drug candidates. Part 1: From α-Anilinophenylacetamide (α-APA) to imidoyl thiourea (ITU)

R. Pauwels, E. Arnold, P. Janssen, 2001 .

Preparation and reactions of some derivatives of 2,4-benzodiazepines and 1,3-diazepines

D. Ludovici, J. A. Pardoen, H. Heine, 1979 .

Small molecule inhibitors of methionine aminopeptidase type 2 (MetAP-2) fail to inhibit endothelial cell proliferation or formation of microvessels from rat aortic rings in vitro

D. Ludovici, Rose M Tominovich, R. Galemmo, 2004, Angiogenesis.

Small molecule inhibitors of methionine aminopeptidase type 2 (MetAP-2).

D. Ludovici, Dana L. Johnson, Rose M Tominovich, 2004, Angiogenesis.

Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.

D. Ludovici, M. Brandt, T. Hutchinson, 2013, Bioorganic & medicinal chemistry letters.

On the detection of multiple-binding modes of ligands to proteins, from biological, structural, and modeling data

Eddy Arnold, Paul J. Lewi, Kalyan Das, 2003, J. Comput. Aided Mol. Des..

Abstract 4747: Design and synthesis of a series highly potent and bioavailable FASN KR domain inhibitors for cancer

Tianbao Lu, G. Bignan, M. Cummings, 2014 .