H. Ye

发表

Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants.

H. M. Vinkers, A. D. Clark, R. Pauwels, 2004, Journal of medicinal chemistry.

Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues.

R. Pauwels, E. Arnold, F. Daeyaert, 2001, Bioorganic & medicinal chemistry letters.

Efficient synthesis of 3-substituted 2-arylindoles via Suzuki coupling reactions on the solid phase

H. Ye, B. Maryanoff, Han-Cheng Zhang, 2001 .

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.

J. Li, H. Ye, C. Derian, 2004, Bioorganic & medicinal chemistry letters.

Preclinical Characterization of GS-9669, a Thumb Site II Inhibitor of the Hepatitis C Virus NS5B Polymerase

S. Leavitt, T. Appleby, M. Fenaux, 2012, Antimicrobial Agents and Chemotherapy.

Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3.

H. Ye, C. Derian, B. Maryanoff, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of 2-hydroxy-5-methyl-3-hexanone

Baoguo Sun, H. Ye, Hongyu Tian, 2011 .

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.

J. Li, H. Ye, C. Derian, 2004, Bioorganic & medicinal chemistry letters.

Biosynthesis of Tasikamides via Pathway Coupling and Diazonium-Mediated Hydrazone Formation.

H. Ye, Min Liu, M. Fang, 2022, Journal of the American Chemical Society.

Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.

H. Ye, J. Parkinson, G. Phillips, 2008, Bioorganic & medicinal chemistry letters.

Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.

H. Ye, D. Davey, J. Parkinson, 2008, Bioorganic & Medicinal Chemistry Letters.

Carba‐nucleosides as Potent Antagonists of the Adenosine 5′‐Diphosphate (ADP) Purinergic Receptor (P2Y12) on Human Platelets

H. Ye, B. Maryanoff, B. Damiano, 2008, ChemMedChem.

Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients.

W. Zhong, M. Fenaux, H. Ye, 2014, Journal of medicinal chemistry.

Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.

Huiling Yang, T. Appleby, M. Fenaux, 2017, Bioorganic & medicinal chemistry letters.

Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection.

S. Leavitt, T. Appleby, M. Fenaux, 2014, Journal of medicinal chemistry.

Synthesis of macrocycles via cobalt-mediated [2 + 2 + 2] cycloadditions.

A. Moretto, G. Leo, H. Ye, 2005, Journal of the American Chemical Society.

Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues.

R. Pauwels, E. Arnold, F. Daeyaert, 2001, Bioorganic & medicinal chemistry letters.

Application of Sharpless asymmetric epoxidation on the preparation of the optically active flavours 3-methylthiohexanal and 5(6)-butyl-1,4-dioxan-2-one

Baoguo Sun, H. Ye, Hongyu Tian, 2011 .

Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.

J. Haeggström, M. Adler, M. Whitlow, 2008, Bioorganic & medicinal chemistry.

Research on interaction regularities and mechanisms between lactic acid and aroma compounds of Baijiu.

Mingquan Huang, Jinyuan Sun, H. Ye, 2022, Food chemistry.

Synthesis and characteristic odour of optically active 3‐hydroxy‐4‐phenyl‐2‐butanone

Mingquan Huang, Baoguo Sun, H. Ye, 2011 .

Studies of the Synthesis of Rubranitrose and Crystal Structure of Methyl 2,3,6-Trideoxy-3-C-Methyl-3-Nitro-α-D-Ribo-Hexopyranoside

H. Ye, A. Rheingold, G. Yap, 1997 .

Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3.

S. Emanuel, H. Ye, C. Derian, 2003, Bioorganic & medicinal chemistry letters.