T. Spies

发表

Complete sequence and gene map of a human major histocompatibility complex

Gen Tamiya, Simon A. Forbes, Stephan Beck, 1999 .

Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.

Govind Bhagat, Lewis L Lanier, Zhangguo Chen, 2004, Immunity.

Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family

L. Lanier, R. Strong, T. Spies, 2001, Immunogenetics.

MICA Expressed by Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance Plasma Cells Costimulates Pamidronate-Activated γδ Lymphocytes

M. Ferrarini, M. Tresoldi, T. Spies, 2005 .

MICA expressed by multiple myeloma and monoclonal gammopathy of undetermined significance plasma cells Costimulates pamidronate-activated gammadelta lymphocytes.

M. Ferrarini, M. Tresoldi, T. Spies, 2005, Cancer research.

Cloning, characterization, and the complete 56.8-kilobase DNA sequence of the human NOTCH4 gene.

B. Trask, L. Hood, L. Rowen, 1998, Genomics.

Isolation and Characterization of Sucrose:Sucrose 1F-β-d-Fructosyltransferase from Tubers of Helianthus tuberosus L.

T. Spies, R. Beck, W. Praznik, 1990 .

NKG2D Initiates Caspase-Mediated CD3ζ Degradation and Lymphocyte Receptor Impairments Associated with Human Cancer and Autoimmune Disease

C. Yee, T. Spies, A. Stevens, 2010, The Journal of Immunology.

BacteriumPhagocytes Infected with an Intracellular Their Ligands in the Lysis of Mononuclear Role of NK Cell-Activating Receptors and

A. Porgador, P. Barnes, P. Klucar, 2005 .

HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells.

P. Tassone, S. Venuta, M. Fulciniti, 2005, Blood.

Role of NK Cell-Activating Receptors and Their Ligands in the Lysis of Mononuclear Phagocytes Infected with an Intracellular Bacterium1

A. Porgador, P. Barnes, P. Klucar, 2005, The Journal of Immunology.

HLA class I , NKG 2 D , and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells

P. Tassone, S. Venuta, M. Fulciniti, 2004 .

Impairment in Chronic Hepatitis C Virus Dendritic Cells in NK Cell Activation :-Stimulated α A and B Expression on IFN-Critical Role of MHC Class I-Related Chain Miyagi

N. Hayashi, Y. Sasaki, T. Tatsumi, 2003 .

Critical Role of MHC Class I-Related Chain A and B Expression on IFN-α-Stimulated Dendritic Cells in NK Cell Activation: Impairment in Chronic Hepatitis C Virus Infection 1

N. Hayashi, Y. Sasaki, T. Tatsumi, 2003, The Journal of Immunology.

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

T. Spies, S. Bauer, K. Grabstein, 1999 .

Adenovirus vector delivery stimulates natural killer cell recognition

P. Tomasec, R. Stanton, E. Wang, 2007, The Journal of general virology.

Human Epithelial Stress-Inducible MHC Class I-Related Chains Specificity in the Recognition of T Cell Antigen Receptor Engagement and

T. Spies, V. Groh, Jennifer D. Wu, 2002 .

Di(µ-acetato)dialkyldigallium as starting compound for the facile syntheses of digallium derivatives containing bridged or terminally co-ordinated Ga–Ga single bonds

T. Spies, R. Koch, W. Uhl, 1999 .

Association of polymorphisms in the HLA-B region with extended haplotypes

J. Strominger, T. Spies, E. Yunis, 2004, Immunogenetics.

Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells

S. Riddell, T. Spies, V. Groh, 2001, Nature Immunology.

Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

T. Spies, H. El-Gabalawy, J. Nelson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Autocrine/Paracrine IL-15 That Is Required for Type I IFN-Mediated Dendritic Cell Expression of MHC Class I-Related Chain A and B Is Impaired in Hepatitis C Virus Infection 1

N. Hayashi, T. Tatsumi, T. Takehara, 2003, The Journal of Immunology.

Infection and B Is Impaired in Hepatitis C Virus Expression of MHC Class I-Related Chain A for Type I IFN-Mediated Dendritic Cell Autocrine / Paracrine IL-15 That Is Required

N. Hayashi, T. Tatsumi, T. Takehara, 2003 .

Promoter Region Architecture and Transcriptional Regulation of the Genes for the MHC Class I-Related Chain A and B Ligands of NKG2D1

T. Spies, J. Boss, V. Groh, 2007, The Journal of Immunology.

Ligands of NKG 2 D the MHC Class I-Related Chain A and B Transcriptional Regulation of the Genes for Promoter Region Architecture

T. Spies, J. Boss, V. Groh, 2006 .

Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus

C. Turtle, S. Riddell, T. Spies, 2009, The Journal of experimental medicine.

Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

H. Orr, J. Strominger, B. Koller, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Soluble MICB in Plasma and Urine Explains Population Expansions of NKG2D+CD4 T Cells Inpatients with Juvenile-Onset Systemic Lupus Erythematosus

T. Spies, A. Stevens, V. Groh, 2017, Open journal of immunology.

Complex structure of the activating immunoreceptor NKG2D and its MHC class I–like ligand MICA

R. Strong, T. Spies, B. Willcox, 2001, Nature Immunology.

CTL in the Tissue Microenvironment IL-15 Costimulate CD28-Negative Effector Cutting Edge: NKG2D Receptors Induced by

T. Spies, B. Jabri, V. Groh, 2001 .

Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

J. Delrow, P. Porter, T. Spies, 2014, PloS one.

Fructo-oligosaccharides from Urginea maritima.

T. Spies, W. Praznik, 1993, Carbohydrate research.

The structure of the fructan sinistrin from Urginea maritima.

T. Spies, F. Altmann, A. Hofinger, 1992, Carbohydrate research.

Fructo-oligosaccharides from the stems of Triticum aestivum.

T. Spies, A. Hofinger, W. Praznik, 1992, Carbohydrate research.

Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15

M. Tretiakova, E. Ebert, A. Lin, 2009, The Journal of experimental medicine.

Intracellular Retention of the MHC Class I-Related Chain B Ligand of NKG2D by the Human Cytomegalovirus UL16 Glycoprotein1

S. Riddell, T. Spies, D. Cosman, 2003, The Journal of Immunology.

Adenovirus E3/19K Promotes Evasion of NK Cell Recognition by Intracellular Sequestration of the NKG2D Ligands Major Histocompatibility Complex Class I Chain-Related Proteins A and B

P. Tomasec, R. Stanton, E. Wang, 2008, Journal of Virology.

Association of four HLA class III region genomic markers with HLA haplotypes.

J. Strominger, J. Hansen, T. Spies, 1991, Tissue antigens.

Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands

R. Strong, T. Spies, V. Groh, 2007, Nature.

Systemic NKG2D Down-Regulation Impairs NK and CD8 T Cell Responses In Vivo1

H. Rammensee, H. Mittrücker, S. Welte, 2005, The Journal of Immunology.

Expression of stress-induced MHC class I related chain molecules on human melanoma.

J. Becker, E. Bröcker, T. Spies, 2002, The Journal of investigative dermatology.

Induction of T cell alertness by bacterial colonization of intestinal epithelium

T. Spies, 2002, Proceedings of the National Academy of Sciences of the United States of America.

MICA Engagement by Human Vγ2Vδ2 T Cells Enhances Their Antigen-Dependent Effector Function

T. Spies, C. Kuijl, V. Groh, 2001 .

Expression of nonclassical class I molecules by intestinal epithelial cells

D. Geraghty, L. Mayer, T. Spies, 2007, Inflammatory bowel diseases.

Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: Role of uric acid accumulation in gemcitabine-induced MICA/B expression

P. Gattuso, H. Kaufman, T. Spies, 2011, BMC Cancer.

T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cells.

T. Spies, V. Groh, Jennifer D. Wu, 2002, Journal of immunology.

Gene organization of DC and DX subregions of the human major histocompatibility complex.

C. Auffray, J. Strominger, J. Lillie, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis.

P. Klenerman, T. Spies, A. Müller, 2008, Clinical immunology.

Restriction fragment length polymorphism (RFLP) of two HLA-B-associated transcripts (BATs) genes in healthy Danes.

L. Fugger, J. Strominger, N. Morling, 1990, Tissue antigens.

Polymorphism in the tumor necrosis factor gene: Association with HLA-B and DR haplotypes

J. Strominger, J. Hansen, T. Spies, 1988 .

Structural organization of the DR subregion of the human major histocompatibility complex.

J. Strominger, T. Spies, J. Boss, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene.

J. Strominger, M. Colonna, E. Ciccone, 1992, Proceedings of the National Academy of Sciences of the United States of America.

9.7-03 Association of four class III genomic markers mapping near TNF with extended HLA-A-B-DR haplotypes

J. Strominger, J. Hansen, T. Spies, 1989 .

A highly divergedβ1 exon in theDR region of the human MHC: Sequence and evolutionary implications

J. Strominger, T. Spies, J. Boss, 2004, Immunogenetics.

Restriction fragment length polymorphisms and an HLA-DRw52-associated split.

J. Strominger, D. Glass, T. Spies, 1988, Human immunology.

Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells.

S. Riddell, C. Yee, T. Spies, 2005, Proceedings of the National Academy of Sciences of the United States of America.

New genes in the MHC that encode proteins for antigen processing.

R. Demars, T. Spies, 1992, Trends in cell biology.

Haplotypic variation of the transporter associated with antigen processing (TAP) genes and their extension of HLA class II region haplotypes

M. Carrington, D. Mann, M. Colonna, 2004, Immunogenetics.

Conserved Amino Acids within the Adenovirus 2 E3/19K Protein Differentially Affect Downregulation of MHC Class I and MICA/B Proteins

Y. Bromberg, T. Spies, Minghui Ao, 2009, The Journal of Immunology.

Affect Downregulation of MHC Class I and Adenovirus 2 E 3 / 19 K Protein Differentially Conserved Amino Acids within the Beatrice Menz

Y. Bromberg, T. Spies, Minghui Ao, 2009 .

Gene organization of DC and DX si histocompatibility complex (gene sequences/promoters/DNA-DNA hybridization/HLA antigens

C. Auffray, J. Strominger, J. Lillie, 2016 .

Regulation of the class II-associated invariant chain gene in normal and mutant B lymphocytes.

J. Strominger, P. Ford, T. Spies, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Fas ligand–mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity

T. Spies, K. Smythe, V. Groh, 2006, Nature Immunology.

Immunostimulation by induced expression of NKG2D and its MIC ligands in HTLV-1-associated neurologic disease

L. Corey, Yuetsu Tanaka, T. Spies, 2006, Immunogenetics.

R. Stanton, E. Wang, G. Wilkinson, 2014 .

Class I Chain-Related Proteins A and B . NKG 2 D Ligands Major Histocompatibility Complex Recognition by Intracellular Sequestration of the Adenovirus E 3 / 19 K Promotes Evasion of NK Cell 2008

P. Tomasec, R. Stanton, E. Wang, 2008 .

Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B.

J. Strominger, T. Spies, M. Bresnahan, 1989, Proceedings of the National Academy of Sciences of the United States of America.

TheB144-H-2Dbinterval and the location of a mouse homologue of the human D6S81E locus

D. Chaplin, T. Spies, J. M. Wroblewski, 2005, Immunogenetics.

Mapping of a Hot Spot in the Major Recombination Area of the Mouse H-2 Complex

R. Campbell, T. Spies, P. Demant, 1991 .

Characterisation of the (1→4)-α-d-glucan-branching 6-glycosyltransferase by in vitro synthesis of branched starch polysaccharides

T. Spies, A. Huber, W. Praznik, 1992 .

A new cluster of genes within the human major histocompatibility complex.

J. Strominger, T. Spies, G. Blanck, 1989, Science.

Human Cytomegalovirus UL16 Glycoprotein I-Related Chain B Ligand of NKG2D by the Intracellular Retention of the MHC Class

S. Riddell, T. Spies, D. Cosman, 2003 .

Effects on Tumor Development and Metastatic Dissemination by the NKG2D Lymphocyte Receptor Expressed on Cancer Cells

D. McDonald, T. Spies, T. Gooley, 2013, Oncogene.

Synthesis and structure of an alkylgallium bridged [1,1]ferrocenophane

T. Spies, W. Uhl, In-Su Hahn, 2001 .

Circularized copies of amplifiable resistance genes from Haemophilus influenzae plasmids

T. Spies, R. Laufs, 1983, Journal of bacteriology.

Amplification of resistance genes in Haemophilus influenzae plasmids

T. Spies, R. Laufs, F. Riess, 1983, Journal of bacteriology.

Antimicrobial activity and biocompatibility of polyurethane and silicone catheters containing low concentrations of silver: a new perspective in prevention of polymer-associated foreign-body-infections.

T. Spies, J. Guggenbichler, M. Böswald, 1995, Zentralblatt fur Bakteriologie : international journal of medical microbiology.

Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding

T. Spies, C. López-Larrea, V. Groh, 2012, Cancer Immunology, Immunotherapy.

The Reactions of R2Ga−GaR2 and R2In−InR2 [R = CH(SiMe3)2] with Protic Reagents: Substituent Exchange versus Cleavage of the Element−Element Bond

W. Frank, T. Spies, W. Uhl, 1998 .

Synthesis of a Large Organometallic Macrocycle Comprising Four Ga−Ga Bonds and Four Bridging Ferrocene Dicarboxylato Ligands†

W. Kaim, T. Spies, R. Winter, 2000 .

THE FORMATION OF MACROCYCLIC COMPOUNDS CONTAINING TWO GA-GA BONDS BY THE REACTION OF TETRAALKYLDIGALLANE(4) R2GA-GAR2 R = CH(SIME3)2 WITH DICARBOXYLIC ACIDS

T. Spies, W. Saak, W. Uhl, 1998 .

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

P. Cresswell, V. Cerundolo, M. Colonna, 1992, Nature.

Clinicopathological significance of major histocompatibility complex class I-related chain a and B expression in thyroid cancer.

P. Gattuso, T. Spies, S. Caillat-Zucman, 2006, The Journal of clinical endocrinology and metabolism.

Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid

N. Hayashi, Y. Sasaki, T. Tatsumi, 2003, International journal of cancer.

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

C. Yee, T. Spies, V. Groh, 2002, Nature.

Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells.

P. Cresswell, J. Pober, T. Spies, 1992, Journal of immunology.

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

A. Goldberg, K. Rock, M. Gaczynska, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A second lineage of mammalian major histocompatibility complex class I genes.

D. Geraghty, S. Bahram, T. Spies, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region.

J. Strominger, S. Bahram, T. Spies, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

Robert DeMars, R. Demars, T. Spies, 1991, Nature.

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

R. Demars, T. Spies, E. Mellins, 1990, Nature.

Genetic Complexity and Expression of Human Class II Histocompatibility Antigens

J. M. Boss, J. Strominger, A. Korman, 1985, Immunological reviews.

The complete genomic sequence of 424,015 bp at the centromeric end of the HLA class I region: gene content and polymorphism.

D. Geraghty, T. Guillaudeux, M. Janer, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Allelic variants of the human putative peptide transporter involved in antigen processing.

T Spies, J. Strominger, M. Colonna, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of a γδ T-cell receptor specific for the human MHC class I homolog MICA

R. Strong, M. Holmes, T. Spies, 2011, Proceedings of the National Academy of Sciences.

T Cell Antigen Receptor Engagement and Specificity in the Recognition of Stress-Inducible MHC Class I-Related Chains by Human Epithelial γδ T Cells1

T. Spies, V. Groh, Jennifer D. Wu, 2002, The Journal of Immunology.

Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2).

P. van Endert, P. Cresswell, T. Spies, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules

P. Cresswell, T. Spies, J. Driscoll, 1992, Nature.

Immunobiology and Conflicting Roles of the Human NKG2D Lymphocyte Receptor and Its Ligands in Cancer

T. Spies, V. Groh, A. El-Gazzar, 2013, The Journal of Immunology.

Detection of enzymatically formed14C-labelled fructan oligomers by means of size exclusion chromatography with an on-line liquid scintillation counter

T. Spies, A. Huber, R. Beck, 1988 .

Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex.

W. Fiers, C. Morton, J. Strominger, 1986, Proceedings of the National Academy of Sciences of the United States of America.

A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain.

J. Strominger, J. Banerji, T. Spies, 1990, Proceedings of the National Academy of Sciences of the United States of America.

P1 and cosmid clones define the organization of 280 kb of the mouse H-2 complex containing the Cps-1 and Hsp70 loci

K. Buetow, C. Hunt, D. Chaplin, 2004, Immunogenetics.

Diversification, expression, and γδ T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules

T. Spies, V. Groh, A. Steinle, 1998 .

SB subregion of the human major histocompatibility complex: gene organization, allelic polymorphism and expression in transformed cells.

C. Auffray, J. Strominger, T. Spies, 1985, The EMBO journal.

PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex

T. Spies, C. David, W. Lafuse, 2004, Immunogenetics.

MIC expression in renal and pancreatic allografts.

D. Mann, J. Papadimitriou, C. Drachenberg, 2002, Transplantation.

Control of Tumor Initiation by NKG2D Naturally Expressed on Ovarian Cancer Cells12

R. Strong, C. Drescher, T. Spies, 2017, Neoplasia.

Regulation of NKG2D ligands: a purposeful but delicate affair

T. Spies, 2008, Nature Immunology.

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. 1990.

R. Demars, S. Bahram, T. Spies, 1991, Journal of immunology.

Structure and phylogenetic interpretation of diplopod eyes (Diplopoda)

T. Spies, 1981, Zoomorphology.

Natural cytotoxicity receptors: influenza virus in the spotlight

T. Spies, V. Groh, 2006, Nature Immunology.

Analysis of the acute cytotoxicity of the erlanger silver catheter

T. Spies, J. Guggenbichler, M. Böswald, 2007, Infection.

Dap10 and Dap12 Form Distinct, but Functionally Cooperative, Receptor Complexes in Natural Killer Cells

Jun Wu, L. Lanier, J. Phillips, 2000, The Journal of experimental medicine.

208 EFFECT OF REFRIGERATION AND CRYOPRESERVATION ON THE QUALITY OF LION EPIDIDYMAL SPERMATOZOA

T. Spies, E. Roldan, F. Martínez-Pastor, 2004 .

203 TIMING OF IN VITRO OOCYTE MATURATION IN SPRINGBOK (ANTIDORCAS MARSUPIALIS), BLACK WILDEBEEST (CONNECHAETES GNU), BLESBOK (DAMALISCUS DORCUS PHILLIPSI), AND REEDBUCK (REDUNCA ARUNDINUM)

R. Krisher, T. Spies, D. Gardner, 2004 .

Corrigendum: Fas ligand–mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity

T. Spies, K. Smythe, V. Groh, 2006, Nature Immunology.

TLR8 agonist VTX-2337 enhances NKG2D-mediated cytotoxicity of NK cells

R. Hershberg, Hailing Lu, T. Spies, 2013, Journal of Immunotherapy for Cancer.

Preparation and Characterization of Aqueous Inulin/Exo-Inulinase Systems

T. Spies, A. Huber, W. Praznik, 1993 .