A. Manuel

发表

Predicting regulatory variants using a dense epigenomic mapped CNN model elucidated the molecular basis of trait-tissue associations

Zhongming Zhao, P. Jia, Guangsheng Pei, 2020, Nucleic acids research.

Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data.

Kathryn S. Burch, B. Pasaniuc, Huwenbo Shi, 2020, American journal of human genetics.

Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data

Kathryn S. Burch, B. Pasaniuc, Huwenbo Shi, 2019, bioRxiv.

TSEA-DB: a trait–tissue association map for human complex traits and diseases

Zhongming Zhao, P. Jia, Guangsheng Pei, 2019, Nucleic Acids Res..

Dense module searching for gene networks associated with multiple sclerosis

Zhongming Zhao, P. Jia, Yulin Dai, 2020, BMC Medical Genomics.

A single-cell atlas of the human brain in Alzheimer’s disease and its implications for personalized drug repositioning

P. Jia, Guangsheng Pei, A. Manuel, 2022, bioRxiv.

Prioritization of risk genes in multiple sclerosis by a refined Bayesian framework followed by tissue-specificity and cell type feature assessment

Yulin Dai, A. Manuel, Andi Liu, 2022, BMC Genomics.

CSEA-DB: an omnibus for human complex trait and cell type associations

Peilin Jia, Zhongming Zhao, Ruifeng Hu, 2020, Nucleic Acids Res..

Distinct effect of prenatal and postnatal brain expression across 20 brain disorders and anthropometric social traits: a systematic study of spatiotemporal modularity

Zhongming Zhao, P. Jia, Yulin Dai, 2021, Briefings Bioinform..

WebCSEA: web-based cell-type-specific enrichment analysis of genes

P. Jia, Xianjun Dong, Ruifeng Hu, 2022, Nucleic Acids Res..

Effects of Various Alpha-1 Antitrypsin Supplement Dosages on the Lung Microbiome and Metabolome

Giri Narasimhan, Kalai Mathee, Trevor Cickovski, 2019, ICCABS.

Enzalutamide-induced signatures revealed by epigenetic plasticity using single-cell multi-omics sequencing in prostate cancer

Huihui Fan, A. Manuel, Jinze Li, 2023, Molecular therapy. Nucleic acids.

A gene regulatory network approach harmonizes genetic and epigenetic signals and reveals repurposable drug candidates for multiple sclerosis.

P. Jia, Yulin Dai, A. Manuel, 2022, Human Molecular Genetics.

Identifying candidate genes and drug targets for Alzheimer's disease by an integrative network approach using genetic and brain region-specific proteomic data.

P. Jia, Yulin Dai, A. Manuel, 2022, Human Molecular Genetics.

Disentangling accelerated cognitive decline from the normal aging process and unraveling its genetic components: A neuroimaging-based deep learning approach

Yulin Dai, A. Manuel, B. Fernandes, 2023, Research square.

Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease

A. Manuel, B. Fernandes, Andi Liu, 2024, Research square.

Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.

Yulin Dai, A. Manuel, B. Fernandes, 2024, Journal of Alzheimer's disease : JAD.