R. Fairchild

发表

Natural Killer Cells: Critical Effectors During Antibody-Mediated Rejection of Solid Organ Allografts.

W. Baldwin, S. Miyairi, A. Valujskikh, 2020, Transplantation.

Early T cell infiltration is modulated by programed cell death-1 protein and its ligand (PD-1/PD-L1) interactions in murine kidney transplants.

W. Baldwin, A. Valujskikh, R. Fairchild, 2020, Kidney international.

On the Road, Looking for Signposts to Tolerance: Making Progress or Spinning Wheels?

S. Feng, R. Fairchild, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Type 6 and 19 pneumococcal polysaccharides coupled to erythrocytes elicit pneumococcal cell wall‐specific primary IgM responses and capsular polysaccharide‐specific secondary IgG responses

R. Fairchild, H. Braley‐Mullen, G. Milligan, 1990, European journal of immunology.

Anti-malaria drug blocks proteotoxic stress response: Anti-cancer implications

A. Gudkov, A. Almasan, R. Fairchild, 2009, Cell cycle.

CXC Chemokine Ligand 9/Monokine Induced by IFN-γ Production by Tumor Cells Is Critical for T Cell-Mediated Suppression of Cutaneous Tumors1

J. Finke, C. Tannenbaum, J. Farber, 2007, The Journal of Immunology.

cell regulation of effector CD 8 T cell development for contact hypersensitivity responses

R. Fairchild, A. Gorbachev, D. Kish, 2005 .

CD8+ T cells produce IL‐2, which is required for CD4+CD25+ T cell regulation of effector CD8+ T cell development for contact hypersensitivity responses

R. Fairchild, A. Gorbachev, D. Kish, 2005, Journal of leukocyte biology.

Heart Allografts Are under Strict Regulation Rejection of Single Class II MHC-Disparate Alloreactive T Cell Responses and Acute and

S. Schenk, K. Fukamachi, L. Turka, 2005 .

Alloreactive T Cell Responses and Acute Rejection of Single Class II MHC-Disparate Heart Allografts Are under Strict Regulation by CD4+CD25+ T Cells1

S. Schenk, K. Fukamachi, L. Turka, 2005, The Journal of Immunology.

CXCR3 Antagonism Impairs the Development of Donor-Reactive, IFN-&ggr;-Producing Effectors and Prolongs Allograft Survival

R. Fairchild, T. Sullivan, J. Medina, 2009, Transplantation.

Chemokine-directed strategies to attenuate allograft rejection.

R. Fairchild, J. Rosenblum, A. Schenk, 2008, Clinics in laboratory medicine.

Monokine Induced by IFN-γ Is a Dominant Factor Directing T Cells into Murine Cardiac Allografts During Acute Rejection1

M. Burdick, R. Strieter, R. Fairchild, 2001, The Journal of Immunology.

Chemokine and chemokine receptor gene expression indicates acute rejection of human cardiac transplants1

P. McCarthy, N. Ratliff, A. Novick, 2003, Transplantation.

Chemokine and receptor-gene expression during early and late acute rejection episodes in human cardiac allografts

P. McCarthy, N. Ratliff, A. Novick, 2003, Transplantation.

Groα‐mediated recruitment of neutrophils is required for elicitation of contact hypersensitivity

C. Tannenbaum, R. Fairchild, T. Hamilton, 1999 .

Interferon-gamma inducible protein (IP-10) expression is mediated by CD8+ T cells and is regulated by CD4+ T cells during the elicitation of contact hypersensitivity.

R. Fairchild, T. Kondo, H. Xu, 1996, The Journal of investigative dermatology.

Interleukin-27 promotes CD8+ T cell reconstitution following antibody-mediated lymphoablation.

A. Valujskikh, R. Fairchild, R. Fan, 2019, JCI insight.

Chemokines: directing leukocyte infiltration into allografts.

R. Fairchild, T. el-Sawy, Nader M Fahmy, 2002, Current opinion in immunology.

Expression of chemokine genes during rejection and long-term acceptance of cardiac allografts.

C. Orosz, R. Fairchild, A. Vanbuskirk, 1997, Transplantation.

Anti‐huCD20 Antibody Therapy for Antibody‐Mediated Rejection of Renal Allografts in a Mouse Model

W. Baldwin, H. Tsuda, N. Nonomura, 2015, American Journal of Transplantation.

Antibody‐Mediated Rejection: Emergence of Animal Models to Answer Clinical Questions

A. Valujskikh, R. Fairchild, W. Baldwin, III, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Aquaporin 4 blockade improves survival of murine heart allografts subjected to prolonged cold ischemia

G. Farr, A. Valujskikh, R. Fairchild, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Lessons and limits of mouse models.

Michelle L. Miller, A. Chong, R. Fairchild, 2013, Cold Spring Harbor perspectives in medicine.

Immunological Challenges of Cardiac Transplantation: The need for Better Animal Models to Answer Current Clinical Questions

W. Baldwin, R. Fairchild, C. Morrell, 2009, Journal of Clinical Immunology.

Interferon Gamma ELISPOT Testing as a Risk‐Stratifying Biomarker for Kidney Transplant Injury: Results From the CTOT‐01 Multicenter Study

P. Nickerson, D. Rush, R. Formica, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival.

R. Colvin, U. Maggiore, W. Baldwin, 2017, Journal of the American Society of Nephrology : JASN.

Effects of T Cell Frequency and Graft Size on Transplant Outcome in Mice 1

S. Schenk, A. Valujskikh, R. Fairchild, 2004, The Journal of Immunology.

CD4+CD25+ regulatory T cells utilize FasL as a mechanism to restrict DC priming functions in cutaneous immune responses

R. Fairchild, A. Gorbachev, 2010, European journal of immunology.

Anti-malaria drug blocks proteotoxic stress response:

A. Gudkov, A. Almasan, R. Fairchild, 2010 .

Early increased chemokine expression and production in murine allogeneic skin grafts is mediated by natural killer cells.

A. Novick, R. Fairchild, Y. Watarai, 2000, Transplantation.

CXCL9 Antagonism Further Extends Prolonged Cardiac Allograft Survival in CCL19/CCL21‐Deficient Mice

Zhiliang Wang, A. Thomson, T. Kakiuchi, 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Continuous function of 80 primary renal allografts for 30–47 years with maintenance prednisone and azathioprine/mycophenolate mofetil therapy: A clinical mosaic of long‐term successes

W. Baldwin, J. Schold, J. Nally, 2020, Clinical transplantation.

Intraallograft Chemokine RNA and Protein During Rejection of MHC-Matched/Multiple Minor Histocompatibility-Disparate Skin Grafts1

C. Tannenbaum, R. Fairchild, T. Hamilton, 2000, The Journal of Immunology.

Histocompatibility-Disparate Skin During Rejection of MHC-Matched/Multiple Intraallograft Chemokine RNA and Protein

C. Tannenbaum, R. Fairchild, T. Hamilton, 2000 .

T cell infiltration into class II MHC-disparate allografts and acute rejection is dependent on the IFN-gamma-induced chemokine Mig.

A. Novick, R. Fairchild, H. Toma, 1999, Journal of immunology.

T cell-dependent acceleration of chemoattractant cytokine gene expression during secondary rejection of allogeneic skin grafts.

A. Novick, R. Fairchild, Y. Watarai, 1997, Transplantation.

Induction of chemokine gene expression during allogeneic skin graft rejection.

A. Novick, R. Fairchild, H. Toma, 1996, Transplantation.

CD4+ T lymphocytes produce adiponectin in response to transplants.

W. Baldwin, A. Valujskikh, R. Fairchild, 2017, JCI insight.

Effects of green tea polyphenols on murine transplant-reactive T cell immunity.

R. Fairchild, P. Heeger, H. Amano, 2004, Clinical immunology.

Effector Functions of Donor‐Reactive CD8 Memory T Cells Are Dependent on ICOS Induced During Division in Cardiac Grafts

A. Valujskikh, R. Fairchild, M. Rabant, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Recipient LAG3 deficiency results in antibody-mediated rejection of mouse renal allografts

W. Baldwin, A. Valujskikh, R. Fairchild, 2020, The Journal of Immunology.

Hapten Application to the Skin Induces an Inflammatory Program Directing Hapten-Primed Effector CD8 T Cell Interaction with Hapten-Presenting Endothelial Cells

W. Baldwin, R. Fairchild, D. Kish, 2011, The Journal of Immunology.

Endothelial Cells Interaction with Hapten-Presenting Hapten-Primed Effector CD 8 T Cell Inflammatory Program Directing Hapten Application to the Skin Induces an

W. Baldwin, R. Fairchild, D. Kish, 2011 .

Endothelial Cells Interaction with HaptenPresenting HaptenPresenting HaptenPresenting HaptenPrimed HaptenPrimed HaptenPrimed Effector CD 8 T Cell Inflammatory Program Directing Hapten Application to the Skin Induces an

W. Baldwin, R. Fairchild, D. Kish, 2011 .

Memory T Cells in Transplantation

R. Fairchild, C. Su, Charles A. Su, 2014, Current Transplantation Reports.

B cells in cardiac transplants: from clinical questions to experimental models.

M. Halushka, W. Baldwin, A. Valujskikh, 2012, Seminars in immunology.

Regulatory function of CD4+CD25+ T cells from Class II MHC‐deficient mice in contact hypersensitivity responses

R. Fairchild, A. Gorbachev, D. Kish, 2007, Journal of leukocyte biology.

γδ T Cells Coexpressing Gut Homing α4β7 and αE Integrins Define a Novel Subset Promoting Intestinal Inflammation

R. Fairchild, T. Pizarro, B. Min, 2017, The Journal of Immunology.

The Yin and Yang of IFN‐γ in Allograft Rejection

R. Fairchild, 2003 .

Early T cell response to allografts occurring prior to alloantigen priming up-regulates innate-mediated inflammation and graft necrosis.

R. Fairchild, T. el-Sawy, M. Miura, 2004, The American journal of pathology.

Early Chemokine Cascades in Murine Cardiac Grafts Regulate T Cell Recruitment and Progression of Acute Allograft Rejection1

D. Remick, R. Fairchild, K. Morita, 2001, The Journal of Immunology.

Progression of Acute Allograft Rejection Cardiac Grafts Regulate T Cell Recruitment Early Chemokine Cascades in Murine

D. Remick, R. Fairchild, A. Kapoor, 2001 .

Intragraft expression of chemokine gene occurs early during acute rejection of allogeneic cardiac grafts.

A. Novick, R. Fairchild, A. Kapoor, 2000, Transplantation proceedings.

Early and late chemokine cascades during acute allograft rejection

R. Fairchild, A. Kapoor, 2000 .

EARLY EXPRESSION OF INTERFERON-g INDUCIBLE PROTEIN 10 AND MONOKINE INDUCED BY INTERFERON-g IN CARDIAC ALLOGRAFTS IS MEDIATED BY CD8 1 T CELLS 1

R. Fairchild, A. Kapoor, K. Morita, 2000 .

Early expression of interferon-gamma inducible protein 10 and monokine induced by interferon-gamma in cardiac allografts is mediated by CD8+ T cells.

R. Fairchild, A. Kapoor, K. Morita, 2000, Transplantation.

Key Role for CD4 T Cells During Mixed Antibody‐Mediated Rejection of Renal Allografts

R. Pelletier, J. Wang, R. Fairchild, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Adverse Outcomes of Tacrolimus Withdrawal in Immune-Quiescent Kidney Transplant Recipients.

P. Nickerson, D. Rush, R. Formica, 2015, Journal of the American Society of Nephrology : JASN.

Quinacrine inhibits the epidermal dendritic cell migration initiating T cell‐mediated skin inflammation

A. Gudkov, R. Fairchild, K. Gurova, 2007, European journal of immunology.

Memory CD4 T Cells Induce Antibody-Mediated Rejection of Renal Allografts.

W. Baldwin, A. Valujskikh, R. Fairchild, 2016, Journal of the American Society of Nephrology : JASN.

Humoral Mechanisms of Adaptive Immunity

W. Baldwin, R. Fairchild, 2014 .

Neutralization of Groα and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury

D. Remick, R. Fairchild, Qiwei Zhang, 2001 .

Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury.

D. Remick, R. Fairchild, M. Miura, 2001, The American journal of pathology.

CD4+ and CD8+ T Cell Priming for Contact Hypersensitivity Occurs Independently of CD40-CD154 Interactions1

R. Fairchild, P. Heeger, A. Gorbachev, 2001, The Journal of Immunology.

Innate immune responses to transplants: a significant variable with cadaver donors.

W. Baldwin, R. Fairchild, C. Larsen, 2001, Immunity.

Neutrophils mediate parenchymal tissue necrosis and accelerate the rejection of complete major histocompatibility complex-disparate cardiac allografts in the absence of interferon-gamma.

R. Fairchild, T. el-Sawy, M. Miura, 2003, The American journal of pathology.

Allografts During Acute Rejection Factor Directing T Cells into Murine Cardiac Is a Dominant γ Monokine Induced by IFN -

M. Burdick, R. Strieter, R. Fairchild, 2001 .

Role of TNFα in Early Chemokine Production and Leukocyte Infiltration into Heart Allografts

R. Fairchild, A. Schenk, S. Baba, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Cellular, Molecular, and Enzymatic Signatures of Thrombi are Vascular Bed-Dependent

Doran S. Mix, R. Bhandari, W. Baldwin, 2022, bioRxiv.

IFN-γ Production by Memory Helper T Cells Is Required for CD40-Independent Alloantibody Responses

W. Baldwin, A. Valujskikh, R. Fairchild, 2015, The Journal of Immunology.

Peritransplant VLA‐4 blockade inhibits endogenous memory CD8 T cell infiltration into high‐risk cardiac allografts and CTLA‐4Ig resistant rejection

W. Baldwin, R. Abe, S. Miyairi, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

IL-1 Receptor Signaling on Graft Parenchymal Cells Regulates Memory and De Novo Donor-Reactive CD8 T Cell Responses to Cardiac Allografts

W. Baldwin, Toshiaki Tanaka, R. Abe, 2016, The Journal of Immunology.

Graft‐Derived CCL2 Increases Graft Injury During Antibody‐Mediated Rejection of Cardiac Allografts

W. Baldwin, N. Nonomura, S. Takahara, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Endogenous Memory CD8 T Cells Are Activated Within Cardiac Allografts Without Mediating Rejection

W. Baldwin, R. Fairchild, K. Setoguchi, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Transient Lymphopenia Breaks Costimulatory Blockade‐Based Peripheral Tolerance and Initiates Cardiac Allograft Rejection

R. Abe, A. Valujskikh, R. Fairchild, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Antibody‐Mediated Rejection of Single Class I MHC‐Disparate Cardiac Allografts

R. Fairchild, R. P. Bucy, W. Baldwin, III, 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

A TLR5 Agonist Inhibits Acute Renal Ischemic Failure

W. Baldwin, A. Gudkov, R. Fairchild, 2011, The Journal of Immunology.

CXC Chemokine Ligand (CXCL) 9 and CXCL10 Are Antagonistic Costimulation Molecules during the Priming of Alloreactive T Cell Effectors

J. Farber, R. Fairchild, D. Kish, 2010, The Journal of Immunology.

CCR5 Is Required for Regulation of Alloreactive T‐Cell Responses to Single Class II MHC‐Mismatched Murine Cardiac Grafts

R. Fairchild, J. Rosenblum, A. D. Schenk, 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

A randomized prospective trial of low-dose OKT3 induction therapy to prevent rejection and minimize side effects in recipients of kidney transplants.

A. Novick, R. Fairchild, S. Flechner, 1999, Transplantation.

IL-1 Receptor Signaling Is Required at Multiple Stages of Sensitization and Elicitation of the Contact Hypersensitivity Response

R. Fairchild, A. Gorbachev, D. Kish, 2012, The Journal of Immunology.

IL‐15 Induces Alloreactive CD28− Memory CD8 T Cell Proliferation and CTLA4‐Ig Resistant Memory CD8 T Cell Activation

W. Baldwin, R. Fairchild, E. Poggio, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Diversion of CD4+ T cell development from regulatory T helper to effector T helper cells alters the contact hypersensitivity response

R. Fairchild, Hui Xu, N. Diiulio, 1996, European journal of immunology.

Inflammation and Transplantation

W. Baldwin, R. Fairchild, 2017 .

High renal ischemia temperature increases neutrophil chemoattractant production and tissue injury during reperfusion without an identifiable role for CD4 T cells in the injury.

W. Baldwin, R. Fairchild, K. Nonomura, 2009, Transplant immunology.

Antibody-Mediated Rejection of Cardiac Allografts in CCR5-Deficient Recipients1

C. Orosz, A. Novick, R. Fairchild, 2007, The Journal of Immunology.

Cathepsin g is required for sustained inflammation and tissue injury after reperfusion of ischemic kidneys.

N. Fukazawa, R. Fairchild, K. Nonomura, 2007, The American journal of pathology.

CD8+ T cells produce RANTES during acute rejection of murine allogeneic skin grafts.

A. Novick, R. Fairchild, H. Toma, 1999, Transplantation.

Neutrophil Expression of Fas Ligand and Perforin Directs Effector CD8 T Cell Infiltration into Antigen-Challenged Skin

R. Fairchild, N. Gupta, A. Gorbachev, 2012, The Journal of Immunology.

Infiltration into Antigen-Challenged Skin Perforin Directs Effector CD8 T Cell Neutrophil Expression of Fas Ligand and

R. Fairchild, N. Gupta, A. Gorbachev, 2012 .

Induction and regulation of T-cell priming for contact hypersensitivity.

R. Fairchild, A. Gorbachev, Robert L. Fairchild, 2001, Critical reviews in immunology.

Inhibition of Polymorphonuclear Leukocyte–Mediated Graft Damage Synergizes With Short-Term Costimulatory Blockade to Prevent Cardiac Allograft Rejection

R. Strieter, D. Remick, J. Belperio, 2005, Circulation.

CD40 Engagement Enhances Antigen-Presenting Langerhans Cell Priming of IFN-γ-Producing CD4+ and CD8+ T Cells Independently of IL-121

R. Fairchild, A. Gorbachev, 2004, The Journal of Immunology.

IL-12 T Cells + and CD 8 +-Producing CD 4 γ of IFN-Antigen-Presenting Langerhans Cell Priming CD 40 Engagement Enhances

R. Fairchild, A. Gorbachev, 2004 .

Sex-specific T cell exhaustion drives differential immune responses in glioblastoma

M. Ahluwalia, M. McGraw, A. Valujskikh, 2022, bioRxiv.

CD4+ T Cells Regulate CD8+ T Cell-Mediated Cutaneous Immune Responses by Restricting Effector T Cell Development through a Fas Ligand-Dependent Mechanism 1

R. Fairchild, A. Gorbachev, 2004, The Journal of Immunology.

a Fas Ligand-Dependent Mechanism by Restricting Effector T Cell Development Cell-Mediated Cutaneous Immune Responses T + T Cells Regulate CD 8 + CD 4

R. Fairchild, A. Gorbachev, 2004 .

Regulatory role of CD4+ T cells during the development of contact hypersensitivity responses

R. Fairchild, A. Gorbachev, 2001, Immunologic research.

Cytokines and chemokines: roles in the pathophysiology and therapy of ischemia and reperfusion injury

R. Fairchild, M. Araki, A. Schenk, 2004 .

Tumor necrosis factors: The molecules and their emerging role in medicine: Beutler, B. (Ed.). 590 pp. Raven Press, New York, NY. 1992

R. Fairchild, 1993 .

Responses to Antigen Skin Challenge Immune Response Required for IFN-{gamma} Initiate the Innate CD8 T Cells Producing IL-17 and

R. Fairchild, Xiaoxia Li, D. Kish, 2010 .

CD8 T Cells Producing IL-17 and IFN-γ Initiate the Innate Immune Response Required for Responses to Antigen Skin Challenge1

R. Fairchild, Xiaoxia Li, D. Kish, 2009, The Journal of Immunology.

Challenge Required for Responses to Antigen Skin Initiate the Innate Immune Response γ CD 8 T Cells Producing IL-17 and IFN -

R. Fairchild, Xiaoxia Li, D. Kish, 2009 .

Regulation of chemokine expression in the tumor microenvironment.

R. Fairchild, A. Gorbachev, 2014, Critical reviews in immunology.

Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts

W. Baldwin, A. Valujskikh, R. Fairchild, 2016, Current opinion in organ transplantation.

Soluble mediators in the immune system

W. Baldwin, R. Fairchild, C. Su, 2015 .

Act1, a negative regulator in CD40- and BAFF-mediated B cell survival.

E. C. Snow, C. Ware, M. Scott, 2004, Immunity.

In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection.

W. Baldwin, Toshiaki Tanaka, S. Miyairi, 2019, Kidney international.

Taking aim at a moving target: the complexity of immune-mediated organ rejection

R. Fairchild, P. Heeger, 2005 .

Soluble factors in tolerance and contact sensitivity to DNFB in mice. X. IL-2 is the activation signal mediating release of synthesized suppressor factor.

R. Fairchild, J. Moorhead, 1991, Cellular immunology.

Soluble factors in tolerance and contact sensitivity to DNFB in mice. VIII. Regulation of T suppressor cell function by autoreactive T helper cells.

R. Fairchild, J. Moorhead, 1988, Cellular immunology.

Soluble factors in tolerance and contact sensitivity to DNFB in mice. VII. Characterization of a monoclonal, efferent-acting suppressor factor with specificity for DNP/H-2Kd.

R. Fairchild, J. Moorhead, 1987, Cellular immunology.

IL-12 Augments CD8+ T Cell Development for Contact Hypersensitivity Responses and Circumvents Anti-CD154 Antibody-Mediated Inhibition1

R. Fairchild, A. Gorbachev, N. Diiulio, 2001, The Journal of Immunology.

Negative Regulation of CD8+ T Cell Function by the IFN-Induced and Double-Stranded RNA-Activated Kinase PKR1

R. Fairchild, S. Kadereit, Hui Xu, 2000, The Journal of Immunology.

Inhibition of Functional T Cell Priming and Contact Hypersensitivity Responses by Treatment with Anti-Secondary Lymphoid Chemokine Antibody During Hapten Sensitization1

R. Fairchild, P. Heeger, R. Gladue, 2000, The Journal of Immunology.

The Spleen Is the Major Source of Antidonor Antibody‐Secreting Cells in Murine Heart Allograft Recipients

A. Valujskikh, R. Fairchild, R. Fan, 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

A simple and sensitive ELISA to detect immune (γ) interferon induced I-A on a macrophage line

R. Fairchild, J. Moorhead, 1985 .

Inhibition of Src Kinases Combined with CD40 Ligand Blockade Prolongs Murine Cardiac Allograft Survival

R. Fairchild, G. Miller, Qiwei Zhang, 2005, Transplantation.

Development of effector CD8+ T cells in contact hypersensitivity occurs independently of CD4+ T cells.

R. Fairchild, H. Xu, N. Dilulio, 1997, Journal of immunology.

Recipient myeloperoxidase-producing cells regulate antibody-mediated acute versus chronic kidney allograft rejection

S. Hazen, W. Baldwin, S. Miyairi, 2021, JCI insight.

Unexpected role for MHC II–peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo

A. Valujskikh, R. Fairchild, D. Vignali, 2012, Proceedings of the National Academy of Sciences.

Expression of IL-8 during Reperfusion of Renal Allografts Is Dependent on Ischemic Time

A. Novick, Lingmei Zhou, R. Fairchild, 2006, Transplantation.

Sensitization Chemokine Antibody During Hapten Treatment with Anti-Secondary Lymphoid Contact Hypersensitivity Responses by Inhibition of Functional T Cell Priming and

R. Fairchild, P. Heeger, R. Gladue, 2000 .

C1q as a potential tolerogenic therapeutic in transplantation

W. Baldwin, A. Valujskikh, R. Fairchild, 2021, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

IFN-Induced and Double-Stranded RNA-Activated Kinase PKR 1

B. Williams, R. Fairchild, S. Kadereit, 2000 .

RNA-Activated Kinase PKR by the IFN-Induced and Double-Stranded T Cell Function + Negative Regulation of CD 8

B. Williams, R. Fairchild, S. Kadereit, 2000 .

CD4 T Cell Help via B Cells Is Required for Lymphopenia-Induced CD8 T Cell Proliferation

A. Valujskikh, R. Fairchild, R. Fan, 2016, The Journal of Immunology.

Lymphopenia-Induced CD 8 T Cell CD 4 T Cell Help via B Cells Is Required for Valujskikh

A. Valujskikh, R. Fairchild, R. Fan, 2016 .

Allograft Fibrosis—Unmasking the Players at the Dance

R. Fairchild, R. Mannon, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Inhibition Circumvents Anti-CD 154 Antibody-Mediated for Contact Hypersensitivity Responses and T Cell Development + IL-12 Augments CD 8

R. Fairchild, A. Gorbachev, N. Diiulio, 2001 .

Integration of complement and leukocytes in response to allotransplantation

N. Flavahan, W. Baldwin, R. Fairchild, 2002 .

Chronic antagonism of Mig inhibits cellular infiltration and promotes survival of class II MHC disparate skin allografts

A. Novick, R. Fairchild, H. Toma, 2002, Transplantation.

Prolonged class II MHC disparate skin allograft survival by treatment with antibodies to the chemokine Mig.

A. Novick, R. Fairchild, H. Toma, 2001, Transplantation proceedings.

Alloantigen-specific CD8(+) T cells stimulate endothelial cells to produce the T-cell chemoattractants IP-10 and Mig.

A. Novick, R. Fairchild, H. Toma, 2001, Transplantation proceedings.

In Vitro Models of Alloreactivity

W. Baldwin, A. Valujskikh, R. Fairchild, 2014 .

Activated NKT cells increase dendritic cell migration and enhance CD8+ T cell responses in the skin

R. Fairchild, A. Gorbachev, 2006, European journal of immunology.

Absence of Recipient CCR5 Promotes Early and Increased Allospecific Antibody Responses to Cardiac Allografts 1

C. Orosz, A. Novick, R. Fairchild, 2005, The Journal of Immunology.

Responses to Cardiac Allografts and Increased Allospecific Antibody Absence of Recipient CCR5 Promotes Early

C. Orosz, A. Novick, R. Fairchild, 2005 .

Cutaneous Tumors Cease CXCL9/Mig Production as a Result of IFN-γ–Mediated Immunoediting

O. Guryanova, A. Kondratova, R. Fairchild, 2013, The Journal of Immunology.

Characterization of the murine immune response to type 6 pneumococcal polysaccharide

R. Fairchild, H. Braley‐Mullen, 1983, Infection and immunity.

Natural killer cells play a critical role in mediating inflammation and graft failure during antibody-mediated rejection of kidney allografts.

W. Baldwin, Toshiaki Tanaka, N. Masumori, 2016, Kidney international.

Developmental loss, but not pharmacological suppression, of renal carbonic anhydrase 2 results in pyelonephritis susceptibility.

G. Schwartz, R. Fairchild, A. Schwaderer, 2020, American journal of physiology. Renal physiology.

Absence of Allograft ICAM-1 Attenuates Alloantigen-Specific T Cell Priming, But Not Primed T Cell Trafficking into the Graft, to Mediate Acute Rejection1

R. Fairchild, D. Kish, Qiwei Zhang, 2003, The Journal of Immunology.

Acute Rejection Primed T Cell Trafficking into the Graft , to Alloantigen-Specific T Cell Priming , But Not Absence of Allograft ICAM-1 Attenuates

R. Fairchild, D. Kish, Qiwei Zhang, 2003 .

Reconstitution of TCR alpha-chain expression in deletion mutants restores dinitrophenyl-specific/class I MHC-restricted suppressor molecule production.

R. Fairchild, J. McCormack, J. Moorhead, 1995, Journal of immunology.

Production of DNP-specific/class I MHC-restricted suppressor molecules is linked to the expression of T cell receptor alpha- and beta-chain genes.

E. Palmer, R. Fairchild, J. Moorhead, 1993, Journal of immunology.

Soluble factors in tolerance and contact sensitivity to 2,4-dinitro-fluorobenzene in mice. IX. A monoclonal T cell suppressor molecule is structurally and serologically related to the alpha/beta T cell receptor.

R. Fairchild, R. Kubo, J. Moorhead, 1988, Journal of immunology.

Raising the direction signposts that guide T cell trafficking into allografts.

R. Fairchild, 2005, Transplantation.

Neutralization of monokine induced by interferon-gamma during the early posttransplantation period prevents development of chronic allograft vasculopathy and graft fibrosis.

T. Koyanagi, R. Fairchild, K. Morita, 2003, Transplantation proceedings.

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report

T. Mohanakumar, R. Fairchild, C. Cairo, 2017, Transplantation.

Neutrophil Cathepsin G Regulates Dendritic Cell Production of IL-12 during Development of CD4 T Cell Responses to Antigens in the Skin

W. Baldwin, R. Fairchild, N. Dvorina, 2019, The Journal of Immunology.

Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling

M. Suthanthiran, M. Sarwal, E. Reed, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell suppressive function and therapeutic efficacy

W. Baldwin, R. Fairchild, N. Dvorina, 2015, Mucosal Immunology.

Interferon action and apoptosis are defective in mice devoid of 2′,5′‐oligoadenylate‐dependent RNase L

R. Silverman, J. Paranjape, B. Dong, 1997, The EMBO journal.

The Immune Response to Transplanted Organs

W. Baldwin, A. Valujskikh, R. Fairchild, 2011 .

Recent Progress and New Perspectives in Studying T Cell Responses to Allografts

W. Baldwin, A. Valujskikh, R. Fairchild, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

T cell–derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death

Jesse D. Gelles, M. Kelliher, J. Chipuk, 2021, JCI insight.

Linking erythropoietin to Treg-dependent allograft survival through myeloid cells

J. Madsen, P. Cravedi, R. Fairchild, 2022, JCI insight.

Jump‐Starting Alloreactive T Cells With High‐Activation Thresholds‐Donor Langerhans Cells Provide the Charge

R. Fairchild, 2007, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

TLR Engagement Prevents Transplantation Tolerance

S. Akira, L. Molinero, S. Uematsu, 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

C. A. de la Motte, V. Tuohy, Caixia Ma, 2007, Immunity.

Urinary-cell mRNA profile and acute cellular rejection in kidney allografts.

Michael Abecassis, Jun Liu, Michael Riggs, 2013, The New England journal of medicine.

Basic Principles of Immunology in Urology

J. Finke, R. Fairchild, S. Flechner, 2012 .

Human breast microbiome correlates with prognostic features and immunological signatures in breast cancer

C. Eng, S. Grobmyer, R. Fairchild, 2021, Genome medicine.

Endogenous memory T cells with donor‐reactivity: early post‐transplant mediators of acute graft injury in unsensitized recipients

H. Tsuda, R. Fairchild, E. Koritzinsky, 2021, Transplant international : official journal of the European Society for Organ Transplantation.

Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report

J. Friedewald, P. Nickerson, E. Reed, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Primary murine immunoglobulin M responses to certain pneumococcal capsular polysaccharides consist primarily of anti-pneumococcal cell wall carbohydrate antibodies

R. Fairchild, H. Braley‐Mullen, K. Sterner, 1986, Infection and immunity.

T-cell mediated induction of allogeneic endothelial cell chemokine expression

A. Novick, R. Fairchild, H. Toma, 2003, Transplantation.

DNP-specific/class I MHC-restricted suppressor molecules bear determinants of the T cell receptor alpha- and beta-chains. The V beta 8+ chain dictates restriction to either K or D.

R. Fairchild, R. Kubo, J. Moorhead, 1990, Journal of immunology.

Myeloid‐derived suppressor cells increase and inhibit donor‐reactive T cell responses to graft intestinal epithelium in intestinal transplant patients

W. Baldwin, J. Fung, R. Fairchild, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Over-salting ruins the balance of the immune menu.

R. Fairchild, B. Min, 2015, The Journal of clinical investigation.

Large Granular Lymphocyte Leukemia After Renal Transplantation: An Immunologic, Immunohistochemical, and Genotypic Study

R. Fairchild, M. Araki, D. Goldfarb, 2007 .

The neonatal Fc receptor: Key to homeostasic control of IgG and IgG‐related biopharmaceuticals

W. Baldwin, A. Valujskikh, R. Fairchild, 2019, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Effects of Influenza Immunization on Humoral and Cellular Alloreactivity in Humans

D. Hricik, R. Fairchild, M. Budev, 2010, Transplantation.

The intensity of neutrophil infiltration controls the number of antigen‐primed CD8 T cells recruited into cutaneous antigen challenge sites

R. Fairchild, A. Gorbachev, D. Kish, 2004, Journal of leukocyte biology.

T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells

R. Fairchild, H. Xu, H Xu, 1996, The Journal of experimental medicine.

Distinct roles for B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity.

R. Fairchild, P. Heeger, H. Xu, 1997, Journal of immunology.

Complement Dependence of Murine Costimulatory Blockade‐Resistant Cellular Cardiac Allograft Rejection

W. Baldwin, J. Liu, R. Fairchild, 2017, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Juicing Tregs in situ to improve kidney allograft outcomes.

R. Fairchild, 2016, Kidney international.

Multicenter Validation of Urinary CXCL9 as a Risk‐Stratifying Biomarker for Kidney Transplant Injury

P. Nickerson, D. Rush, R. Formica, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Experimental models of cardiac transplantation: design determines relevance.

W. Baldwin, Thomas M. Shroka, R. Fairchild, 2014, Current opinion in organ transplantation.

CD4 T Cell-Mediated Rejection of Cardiac Allografts in B Cell-Deficient Mice1

R. Fairchild, K. Tanabe, J. Rosenblum, 2008, The Journal of Immunology.

CD4 T Cell-Mediated Rejection of Cardiac Allografts in B Cell-Deficient Mice

R. Fairchild, K. Tanabe, J. Rosenblum, 2008 .

Allografts in B Cell-Deficient Mice CD 4 T Cell-Mediated Rejection of Cardiac

R. Fairchild, K. Tanabe, J. Rosenblum, 2008 .

Memory T Cells in Transplantation: Old Challenges Define New Directions

A. Valujskikh, R. Fairchild, M. Nicosia, 2020, Transplantation.

Lymphoid Sequestration of Alloreactive Memory CD4 T Cells Promotes Cardiac Allograft Survival1

A. Valujskikh, R. Fairchild, P. Heeger, 2006, The Journal of Immunology.

Fibroblastic reticular cells orchestrate long-term graft survival following recipient treatment with CD40 ligand–targeted costimulatory blockade

R. Fairchild, 2022, The Journal of clinical investigation.

Donor‐Reactive CD8 Memory T Cells Infiltrate Cardiac Allografts Within 24‐h Posttransplant in Naive Recipients

A. Valujskikh, R. Fairchild, M. Rabant, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Painless Photodynamic Therapy Triggers Innate and Adaptive Immune Responses in a Murine Model of UV‐induced Squamous Skin Pre‐cancer

R. Fairchild, E. Maytin, S. Anand, 2020, Photochemistry and photobiology.

Human neutrophil peptides 1-3 protect the murine urinary tract from uropathogenic Escherichia coli challenge

D. Cines, K. Bdeir, R. Fairchild, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Can Sensitized Lymphocytes Retain Reactivity to Inner Ear Antigens After Retrieval From Frozen Storage?

B. Barna, R. Fairchild, G. Hughes, 1997, The Laryngoscope.

Evaluation of Alloreactivity in Kidney Transplant Recipients Treated with Antithymocyte Globulin Versus IL‐2 Receptor Blocker

W. Baldwin, T. Srinivas, A. Valujskikh, 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Acute and Chronic Rejection: Compartmentalization and Kinetics Ff Counterbalancing Signals in Cardiac Transplants

A. Valujskikh, R. Fairchild, S. Goparaju, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

LFA‐1 Antagonism Inhibits Early Infiltration of Endogenous Memory CD8 T Cells into Cardiac Allografts and Donor‐Reactive T Cell Priming

W. Baldwin, R. Fairchild, K. Setoguchi, 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial

P. Nickerson, R. Formica, D. Brennan, 2022, Journal of the American Society of Nephrology : JASN.

Endogenous Memory CD8 T Cells Directly Mediate Cardiac Allograft Rejection

R. Fairchild, T. Abe, S. Iida, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Skin allograft rejection is suppressed in mice lacking the antiviral enzyme, 2',5'-oligoadenylate-dependent RNase L.

R. Silverman, R. Fairchild, Aimin Zhou, 2002, Viral immunology.

Molecular Signature of Antibody-Mediated Chronic Vasculopathy in Heart Allografts in a Novel Mouse Model.

E. Reed, W. Baldwin, H. Tsuda, 2022, The American journal of pathology.

Antibody‐induced vascular inflammation skews infiltrating macrophages to a novel remodeling phenotype in a model of transplant rejection

E. Reed, Jianquan Hou, R. Fairchild, 2020, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Spatial Multi-omics of Arterial Regions from Cardiac Allograft Vasculopathy Rejected Grafts

E. Reed, W. Baldwin, R. Fairchild, 2023, bioRxiv.

The Last 5 Years of Basic Science Investigation in Transplant Immunology

A. Thomson, R. Fairchild, 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Failure of Costimulatory Blockade-induced Regulatory T Cells to Sustain Long-term Survival of High Ischemic Allografts

H. Tsuda, S. Miyairi, A. Valujskikh, 2023, Transplantation.

B cell–derived IL‐1β and IL‐6 drive T cell reconstitution following lymphoablation

A. Valujskikh, R. Fairchild, R. Fan, 2020, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Allograft dendritic cell p40 homodimers activate donor-reactive memory CD8+ T cells.

Toshiaki Tanaka, H. Tsuda, A. Valujskikh, 2018, JCI insight.

Novel CD8 T Cell Alloreactivities in CCR5-Deficient Recipients of Class II MHC Disparate Kidney Grafts

W. Baldwin, A. Valujskikh, R. Fairchild, 2014, The Journal of Immunology.

The Puzzling Role of CXCR3 and Its Ligands in Organ Allograft Rejection

P. Halloran, R. Fairchild, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Urine CXCL10/IP-10 Fingers Ongoing Antibody-Mediated Kidney Graft Rejection.

M. Suthanthiran, R. Fairchild, 2015, Journal of the American Society of Nephrology : JASN.

Molecular monitoring of alloimmune-mediated injury in kidney transplant patients

R. Fairchild, E. Poggio, O. Traitanon, 2014, Current opinion in nephrology and hypertension.

Anti-donor MHC Class II Alloantibody Induces Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia.

W. Baldwin, A. Valujskikh, R. Fairchild, 2019, Journal of the American Society of Nephrology : JASN.

Immunosuppressive Effects of Silicon Phthalocyanine Photodynamic Therapy

Hui Xu, C. Elmets, R. Fairchild, 1999, Photochemistry and photobiology.

Human breast microbiome correlates with prognostic features and immunological signatures in breast cancer

S. Grobmyer, R. Fairchild, Naseer Sangwan, 2021, Genome Medicine.

What's hot, what's new: Report from the American Transplant Congress 2018

D. Eckhoff, R. Abdi, R. Fairchild, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Acute Humoral Rejection of Renal Allografts in CCR5–/– Recipients

R. Pelletier, R. Fairchild, T. Nadasdy, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Reperfusion Inflammatory State of Human Lungs during Cellular Ex-Vivo Perfusion

H. Elgharably, R. Fairchild, K. Ayyat, 2019, The Journal of Heart and Lung Transplantation.

Transplant Outcome in Mice Effects of T Cell Frequency and Graft Size on

S. Schenk, A. Valujskikh, R. Fairchild, 2003 .

RANTES is produced by CD8+ T cells during acute rejection of skin grafts.

A. Novick, R. Fairchild, A. Kapoor, 2000, Transplantation proceedings.

LAG3 regulates antibody responses in a murine model of kidney transplantation

W. Baldwin, A. Valujskikh, R. Fairchild, 2023, bioRxiv.

Autoantibodies against DNA-topoisomerase I promote renal allograft rejection by increasing alloreactive T cell responses.

W. Baldwin, S. Miyairi, A. Valujskikh, 2023, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Recipient polyclonal B cell activation and immunoglobulin production induced by priming with a retroviral superantigen.

R. Fairchild, M. Caulfield, C. Modlin, 1996, Cellular immunology.

Chemokines and Transplantation

R. Fairchild, Tarek EI-Sawy, 2004 .

The Yin and Yang of IFN-gamma in allograft rejection.

R. Fairchild, 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Monokine induced by interferon-gamma (MIG/CXCL9) is derived from both donor and recipient sources during rejection of class II major histocompatibility complex disparate skin allografts.

J. Farber, R. Fairchild, H. Amano, 2009, The American journal of pathology.

High incidence of delayed renal graft function.

R. Fairchild, M. Araki, D. Goldfarb, 2007, Transplantation.

Acute rejection after liver transplantation with machine perfusion versus static cold storage: A systematic review and meta-analysis

R. Fairchild, K. Hashimoto, C. Quintini, 2023, Hepatology.

Turning on the Lights inside Neutrophils

R. Fairchild, 2016, The Journal of Immunology.

An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell suppressive function and therapeutic efficacy

W. Baldwin, R. Fairchild, N. Dvorina, 2015, Mucosal Immunology.

A RANDOMIZED PROSPECTIVE TRIAL OF OKT3 VS. BASILIXIMAB FOR INDUCTION THERAPY IN RENAL TRANSPLANTATION.: Abstract# 169 Poster Board #‐Session: P16‐I

A. Novick, R. Fairchild, S. Flechner, 2000 .

Macrophage‐inducible C‐type lectin activates B cells to promote T cell reconstitution in heart allograft recipients

A. Valujskikh, R. Fairchild, R. Fan, 2022, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.