D. Mitchison

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Mechanisms of Pyrazinamide Action and Resistance.

Ying Zhang, W. Shi, Wenhong Zhang, 2014, Microbiology spectrum.

Sources of variation in studies of the early bactericidal activity of antituberculosis drugs.

D. Mitchison, F. Sirgel, A. Venter, 2001, The Journal of antimicrobial chemotherapy.

High-dose rifampicin kills persisters, shortens treatment duration, and reduces relapse rate in vitro and in vivo

D. Mitchison, Yanmin Hu, Alexander Liu, 2015, Front. Microbiol..

The diagnosis and therapy of tuberculosis during the past 100 years.

D. Mitchison, 2005, American journal of respiratory and critical care medicine.

The early bactericidal activity of isoniazid related to its dose size in pulmonary tuberculosis.

M. Vandenplas, D. Mitchison, P. Donald, 1997, American journal of respiratory and critical care medicine.

Controlled double-blind study of the effect of rifampin on humoral and cellular immune responses in patients with pulmonary tuberculosis and in tuberculosis contacts.

D. Girling, D. Mitchison, A. Nunn, 1980, The American review of respiratory disease.

Effects of Four Different Meal Types on the Population Pharmacokinetics of Single-Dose Rifapentine in Healthy Male Volunteers

D. Mitchison, J. van der Walt, G. Roscigno, 2010, Antimicrobial Agents and Chemotherapy.

THE TUBERCLE BACILLUS

D. Mitchison, 1959 .

Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications.

D. Mitchison, W. Fox, G. Ellard, 1999, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

FALSE-POSITIVE ACID-FAST SMEARS

D. Mitchison, B. Allen, R. Mitchison, 1975, The Lancet.

Studies on the treatment of tuberculosis undertaken by the British Medical Research Council Tuberculosis Units, 1946-1986, with relevant subsequent publications.

D. Mitchison, W. Fox, G. Ellard, 1999, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Spray Dried Aerosol Particles of Pyrazinoic Acid Salts for Tuberculosis Therapy. [Corrected].

A. Hickey, D. Mitchison, N. Mortensen, 2015, Molecular pharmaceutics.

Mechanisms of Pyrazinamide Action and Resistance.

Ying Zhang, W. Shi, Wenhong Zhang, 2014, Microbiology spectrum.

Chapter 5: Recent Developments in the Study of Pyrazinamide: An Update

D. Mitchison, Ying Zhang, 2011 .

The near future: improving the activity of rifamycins and pyrazinamide.

D. Mitchison, P. Fourie, 2010, Tuberculosis.

Mechanisms of Tuberculosis Chemotherapy

D. Mitchison, 1997 .

Pyrazinamide — on the antituberculosis drug frontline

D. Mitchison, 1996, Nature Medicine.

Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days.

C. Doré, D. Mitchison, A. Jindani, 2003, American journal of respiratory and critical care medicine.

Understanding the chemotherapy of tuberculosis—current problems

D. Mitchison, 1992 .

The Garrod Lecture. Understanding the chemotherapy of tuberculosis--current problems.

D. Mitchison, 1992, The Journal of antimicrobial chemotherapy.

Protein synthesis is shutdown in dormant Mycobacterium tuberculosis and is reversed by oxygen or heat shock.

P. Butcher, D. Mitchison, A. Coates, 1998, FEMS microbiology letters.

Early Bactericidal Activity of Paromomycin (Aminosidine) in Patients with Smear-Positive Pulmonary Tuberculosis

D. Mitchison, L. Danziger, P. Donald, 2000, Antimicrobial Agents and Chemotherapy.

Timing of relapse in short-course chemotherapy trials for tuberculosis.

D. Mitchison, A. Nunn, P. Phillips, 2010, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Tubercle Bacilli Resistant to Isoniazid

D. Mitchison, 1954, British medical journal.

[The detection of isoniazid in urine].

P. Gangadharam, D. Mitchison, E. Short, 1958, Tubercle.

Bactericidal activity of streptomycin, isoniazid, rifampin, ethambutol, and pyrazinamide alone and in combination against Mycobacterium Tuberculosis.

D. Mitchison, V. Aber, J. Dickinson, 2015, The American review of respiratory disease.

CONTROLLED CLINICAL TRIAL OF COMPLETE OPEN SURGICAL DRAINAGE AND OF PREDNISOLONE IN TREATMENT OF TUBERCULOUS PERICARDIAL EFFUSION IN TRANSKEI

D. Girling, D. Gibson, D. Mitchison, 1988, The Lancet.

Rifapentine and isoniazid in the continuation phase of a 6-month regimen. Final report at 5 years: prognostic value of various measures.

D. Mitchison, C. Tam, R. Goodall, 2002, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

In vitro studies on the choice of drugs for intermittent chemotherapy of tuberculosis

D. Mitchison, J. Dickinson, 1966 .

Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months.

D. Mitchison, 1993, The American review of respiratory disease.

Suitability of rifampicin for intermittent administration in the treatment of tuberculosis.

D. Mitchison, J. Dickinson, Jean M. Dickinson, 1970, Tubercle.

Early bactericidal activity of ethambutol, pyrazinamide and the fixed combination of isoniazid, rifampicin and pyrazinamide (Rifater) in patients with pulmonary tuberculosis.

D. Mitchison, P. Donald, F. Sirgel, 1996, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

The early bactericidal activity of rifabutin in patients with pulmonary tuberculosis measured by sputum viable counts: a new method of drug assessment.

D. Mitchison, P. Donald, F. Sirgel, 1993, The Journal of antimicrobial chemotherapy.

Role of individual drugs in the chemotherapy of tuberculosis.

D. Mitchison, 2000, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Suitability of isoniazid and ethambutol for intermittent administration in the treatment of tuberculosis.

D. Mitchison, G. Ellard, J. Dickinson, 1968, Tubercle.

The early bactericidal activity of rifabutin measured by sputum viable counts in Hong Kong patients with pulmonary tuberculosis.

D. Girling, D. Mitchison, W. Yew, 1992, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[Mechanisms of the action of drugs in the short-course chemotherapy].

D. Mitchison, 1985, Bulletin of the International Union against Tuberculosis.

Amikacin in the treatment of pulmonary tuberculosis.

D. Girling, D. Mitchison, W. Yew, 1983, Tubercle.

Influence of initial drug resistance on the response to short-course chemotherapy of pulmonary tuberculosis.

D. Mitchison, A. Nunn, 2015, The American review of respiratory disease.

Experimental models to explain the high sterilizing activity of rifampin in the chemotherapy of tuberculosis.

D. Mitchison, J. Dickinson, 1981, The American review of respiratory disease.

HLA typing in the Hong Kong Chest Service/British Medical Research Council study of factors associated with the breakdown to active tuberculosis of inactive pulmonary lesions.

D. Girling, D. Mitchison, D. Lowrie, 1988, The American review of respiratory disease.

Development of Streptomycin Resistant Strains of Tubercle Bacilli in Pulmonary Tuberculosis

D. Mitchison, 1950, Thorax.

Once-weekly treatment of tuberculosis with the diarylquinoline R207910: a real possibility.

D. Mitchison, E. Nuermberger, 2009, American Journal of Respiratory and Critical Care Medicine.

The control of tuberculosis: progress & prospect.

D. Mitchison, 2005, The Indian journal of medical research.

Shortening the treatment of tuberculosis

D. Mitchison, 2005, Nature Biotechnology.

Sterilizing Activities of Fluoroquinolones against Rifampin-Tolerant Populations of Mycobacterium tuberculosis

D. Mitchison, Yanmin Hu, A. Coates, 2003, Antimicrobial Agents and Chemotherapy.

VIRULENCE IN THE GUINEA-PIG, SUSCEPTIBILITY TO HYDROGEN PEROXIDE, AND CATALASE ACTIVITY OF ISONIAZID-SENSITIVE TUBERCLE BACILLI FROM SOUTH INDIAN AND BRITISH PATIENTS.

D. Mitchison, J. Selkon, J. Lloyd, 1963, The Journal of pathology and bacteriology.

Advances in techniques of testing mycobacterial drug sensitivity, and the use of sensitivity tests in tuberculosis control programmes.

A. Khomenko, D. Mitchison, W. Fox, 1969, Bulletin of the World Health Organization.

Evaluation of New Antituberculosis Drugs in Mouse Models

D. Mitchison, A. Pym, G. Davies, 2007, Antimicrobial Agents and Chemotherapy.

The activity of low-clearance liposomal amikacin in experimental murine tuberculosis.

D. Mitchison, J. Adler-Moore, R. Goodall, 2001, The Journal of antimicrobial chemotherapy.

Infectivity of patients with pulmonary tuberculosis during chemotherapy.

D. Mitchison, 1990, The European respiratory journal.

A comparison of various measures of sensitivity of M. tuberculosis to pyrazinamide.

N. G. Nair, D. Mitchison, S. Radhakrishna, 1970, The Indian journal of medical research.

How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis.

D. Mitchison, 1998, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Community-based short-course treatment of pulmonary tuberculosis in a developing nation.

D. Mitchison, W. Fox, 1992, The American review of respiratory disease.

Drug resistance in mycobacteria.

D. Mitchison, 1984, British medical bulletin.

What is drug resistance?

D. Mitchison, 1969, Tubercle.

The early bactericidal activity of amikacin in pulmonary tuberculosis.

D. Mitchison, P. Donald, F. Sirgel, 2001, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Split‐drug regimens for the treatment of patients with sputum smear‐positive pulmonary tuberculosis – a unique approach

D. Mitchison, R. Prabhaker, G. Sarma, 2004, Tropical medicine & international health : TM & IH.

The action of antituberculosis drugs in short-course chemotherapy.

D. Mitchison, 1985, Tubercle.

The early bactericidal activities of rifampin and rifapentine in pulmonary tuberculosis.

D. Mitchison, R. Rustomjee, G. Roscigno, 2005, American journal of respiratory and critical care medicine.

In vitro properties of rifapentine (MDL473) relevant to its use in intermittent chemotherapy of tuberculosis.

D. Mitchison, J. Dickinson, Jean M. Dickinson, 1987, Tubercle.

Rifapentine and isoniazid in the continuation phase of treating pulmonary tuberculosis. Initial report.

D. Mitchison, C. Lam, C. Leung, 1998, American journal of respiratory and critical care medicine.

Development of rifapentine: the way ahead.

D. Mitchison, 1998, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Bioavailability of Chinese rifapentine during a clinical trial in Hong Kong.

D. Mitchison, C. Lam, C. Tam, 1997, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

The therapy of pulmonary tuberculosis in Kenya: a comparison of the results achieved in controlled clinical trials with those achieved by the routine treatment services.

A. Miller, D. Mitchison, A. Nunn, 1970, Tubercle.

THE EMERGENCE OF ISONIAZID-RESISTANT CULTURES IN PATIENTS WITH PULMONARY TUBERCULOSIS DURING TREATMENT WITH ISONIAZID ALONE OR ISONIAZID PLUS PAS.

D. Mitchison, A. Narayana, J. Selkon, 1964, Bulletin of the World Health Organization.

Antimicrobial therapy of tuberculosis: justification for currently recommended treatment regimens.

D. Mitchison, 2004, Seminars in respiratory and critical care medicine.

The bactericidal activities of antituberculous drugs.

D. Mitchison, J. Selkon, 1956, American review of tuberculosis.

A selective oleic acid albumin agar medium for tubercle bacilli.

D. Mitchison, B. Allen, V. Aber, 1972, Journal of medical microbiology.

Bactericidal action of ofloxacin, sulbactam-ampicillin, rifampin, and isoniazid on logarithmic- and stationary-phase cultures of Mycobacterium tuberculosis

P. Venkatesan, D. Mitchison, C. N. Paramasivan, 1996, Antimicrobial agents and chemotherapy.

Modern methods for assessing the drugs used in the chemotherapy of mycobacterial disease.

D. Mitchison, 1996, Society for Applied Bacteriology symposium series.

Laboratory aspects of intermittent drug therapy

D. Mitchison, J. Dickinson, 1971, Postgraduate medical journal.

The prevalence of drug-resistant tubercle bacilli in untreated patients with pulmonary tuberculosis; a national survey, 1955-56.

D. Mitchison, W. Fox, J. Selkon, 1957, Tubercle.

The occurrence of independent mutations to different types of streptomycin resistance in Bacterium coli.

D. Mitchison, 1953, Journal of general microbiology.

ANTIGENIC DIVERSITY OF MYCOBACTERIUM TUBERCULOSIS AND MYCOBACTERIUM BOVIS DETECTED BY MEANS OF MONOCLONAL ANTIBODIES

J. Iványi, D. Mitchison, A. Coates, 1981, The Lancet.

A randomised Phase II trial to evaluate the toxicity of high-dose rifampicin to treat pulmonary tuberculosis.

D. Mitchison, T. Harrison, G. Borgulya, 2016, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Drug resistance in tuberculosis

D. Mitchison, 2005, European Respiratory Journal.

A multicentre study of the early bactericidal activity of anti-tuberculosis drugs.

D. Mitchison, C. Lam, P. Donald, 2000, The Journal of antimicrobial chemotherapy.

Sulphadimidine Acetylation Test for Classification of Patients as Slow or Rapid Inactivators of Isoniazid

N. G. Nair, D. Mitchison, K. Prema, 1970, British medical journal.

Tubercle bacilli resistant to isoniazid: virulence and response to treatment with isoniazid in guinea-pigs and mice.

D. Mitchison, M. Barnett, S. Busby, 1953, British journal of experimental pathology.

Optimizing Outpatient Serial Sputum Colony Counting for Studies of Tuberculosis Treatment in Resource-Poor Settings

S. Khoo, D. Mitchison, Jenny Allen, 2012, Journal of Clinical Microbiology.

Tuberculosis Diagnosis and Multidrug Resistance Testing by Direct Sputum Culture in Selective Broth without Decontamination or Centrifugation

A. R. Escombe, Eric S. Ramos, C. Evans, 2008, Journal of Clinical Microbiology.

Serodiagnosis of tuberculosis using an ELISA with antigen 5 and a hemagglutination assay with glycolipid antigens. Results in patients with newly diagnosed pulmonary tuberculosis ranging in extent of disease from minimal to extensive.

D. Girling, D. Mitchison, S. Chan, 1990, The American review of respiratory disease.

A comparison of the virulence in guinea-pigs of South Indian and British tubercle bacilli.

D. Mitchison, M. Lancaster, J. Wallace, 1960, Tubercle.

Treatment of Tuberculosis

D. Mitchison, 1980, Journal of the Royal College of Physicians of London.

Sterilising action of pyrazinamide in models of dormant and rifampicin-tolerant Mycobacterium tuberculosis.

D. Mitchison, A. Coates, Y. Hu, 2006, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Comparison of the sterilising activities of the nitroimidazopyran PA-824 and moxifloxacin against persisting Mycobacterium tuberculosis.

D. Mitchison, Yanmin Hu, A. Coates, 2008, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Pyrazinamide and other drugs in tuberculous meningitis.

D. Mitchison, G. Ellard, D. Newton, 1973, Lancet.

The segregation of streptomycin-resistant variants of Mycobacterium tuberculosis into groups with characteristic levels of resistance.

D. Mitchison, 1951, Journal of general microbiology.

Short-course chemotherapy for pulmonary tuberculosis.

D. Mitchison, W. Fox, 1975, The American review of respiratory disease.

Effect of vaccines in a murine model of dormant tuberculosis.

D. Mitchison, J. Dhillon, 1994, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Serum concentrations and antituberculosis activity of thiacetazone.

P. T. Gammon, D. Mitchison, G. Ellard, 1974, Tubercle.

Report on Two Species of the Genus Fusiformis obtained from Pathological Lesions in Man

D. Mitchison, H. Schwabacher, Herta Schwabacher, 1947, Journal of clinical pathology.

Comparison of strains of Mycobacterium tuberculosis from British, Ugandan and Asian immigrant patients: a study in bacteriophage typing, susceptibility to hydrogen peroxide and sensitivity to thiophen-2-carbonic acid hydrazide.

D. Mitchison, C. Collins, B. Allen, 1977, Tubercle.

The early bactericidal activity of drugs in patients with pulmonary tuberculosis.

D. Mitchison, V. Aber, A. Jindani, 2015, The American review of respiratory disease.

A method of estimating streptomycin in serum and other body fluids by diffusion through agar enclosed in glass tubes.

D. Mitchison, C. Spicer, 1949, Journal of general microbiology.

Effects of low incubation temperatures on the bactericidal activity of anti-tuberculosis drugs.

S. Waddell, D. Mitchison, D. Coleman, 2011, The Journal of antimicrobial chemotherapy.

SHORT-COURSE CHEMOTHERAPY FOR TUBERCULOSIS

D. Mitchison, W. Fox, 1976, The Lancet.

SHORT-COURSE CHEMOTHERAPY OF TUBERCULOSIS

D. Girling, D. Mitchison, P. Stradling, 1976, The Lancet.

MYCOBACTERIA: LABORATORY METHODS FOR TESTING DRUG SENSITIVITY AND RESISTANCE.

P HAUDUROY, D. Mitchison, J. Grosset, 1963, Bulletin of the World Health Organization.

Quality control in tuberculosis bacteriology. 1. Laboratory studies on isolated positive cultures and the efficiency of direct smear examination.

D. Mitchison, B. Allen, V. Aber, 1980, Tubercle.

Cumulative effects of pulsed exposures of mycobacterium tuberculosis to isoniazid.

D. Mitchison, A. M. Awaness, 1973, Tubercle.

The pattern of mycobacterial antigen recognition in sera from Mantoux‐negative individuals is essentially unaffected by bacilli Calmette‐Guérin (BCG) vaccination in either South India or London

D. Mitchison, S. Das, P. R. Narayanan, 1992, Clinical and experimental immunology.

Evaluation of a serological test for tuberculosis.

D. Mitchison, B. Allen, V. Aber, 1977, British medical journal.

Experimental infective pneumoconiosis. IV. Massive pulmonary fibrosis produced by coal-mine dust and isoniazid-resistant tubercle bacilli of low virulence.

D. Mitchison, C. Harrison, E. King, 1955, British journal of experimental pathology.

Nicotine and Mycobacteria

D. Mitchison, B. Allen, 1983, Journal of the Royal Society of Medicine.

Prevention of drug resistance by combined drug treatment of tuberculosis.

D. Mitchison, 2012, Handbook of experimental pharmacology.

Hemagglutination tests for tuberculosis with mycobacterial glycolipid antigens. Results in patients with active pulmonary tuberculosis before and during chemotherapy and in healthy tuberculosis contacts.

D. Mitchison, V. Aber, S. Devi, 1981, The American review of respiratory disease.

The use of murine monoclonal antibodies without purification of antigen in the serodiagnosis of tuberculosis.

J. Iványi, D. Mitchison, A. Coates, 1982, Journal of immunological methods.

The early bactericidal activity of ciprofloxacin in patients with pulmonary tuberculosis.

R. Schall, D. Mitchison, P. Donald, 1997, American journal of respiratory and critical care medicine.

The chemotherapy of tuberculosis: past, present and future [State of the art].

D. Mitchison, G. Davies, D Mitchison, 2012, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

The curious characteristics of pyrazinamide: a review.

D. Mitchison, Ying Zhang, Y Zhang, 2003, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Preventive chemotherapy of tuberculosis in Cornell model mice with combinations of rifampin, isoniazid, and pyrazinamide

D. Mitchison, K. Sole, J. Dhillon, 1996, Antimicrobial agents and chemotherapy.

Basic mechanisms of chemotherapy.

D. Mitchison, 1979, Chest.

Bactericidal Activity of Streptomycin and Isoniazid Against Tubercle Bacilli

D. Mitchison, B. Singh, 1954, British medical journal.

Streptomycin Resistance in Pulmonary Tuberculosis

D. Mitchison, J CROFTON, D A MITCHISON, 1948, British medical journal.

PROBENECID AND SERUM-RIFAMPICIN

D. Mitchison, B. Allen, A. Levi, 1975, The Lancet.

Prevention of Colds by Vaccination against a Rhinovirus

D. Mitchison, 1965, British medical journal.

Monocyte antimycobacterial activity before and after Mycobacterium bovis BCG vaccination in Chingleput, India, and London, United Kingdom

D. Mitchison, M. Datta, D. Lowrie, 1993, Infection and immunity.

Recombinant interferon-gamma and chemotherapy with isoniazid and rifampicin in experimental murine tuberculosis.

D. Mitchison, A. Coates, D. Lowrie, 1986, British journal of experimental pathology.

The 45 kilodalton molecule of Mycobacterium tuberculosis identified by immunoblotting and monoclonal antibodies as antigenic in patients with tuberculosis.

M. Pallen, D. Mitchison, A. Coates, 1989, British journal of experimental pathology.

Letter: False-positive acid-fast smears.

D. Mitchison, B. Allen, R. Mitchison, 1975, Lancet.

Clinical development of anti-tuberculosis drugs.

D. Mitchison, 2006, The Journal of antimicrobial chemotherapy.

Activity and penetration of antituberculosis drugs in mouse peritoneal macrophages infected with Mycobacterium microti OV254

D. Mitchison, J. Dhillon, 1989, Antimicrobial Agents and Chemotherapy.

Bactericidal activity of the diarylquinoline TMC207 against Mycobacterium tuberculosis outside and within cells.

K. Andries, D. Mitchison, P. Phillips, 2010, Tuberculosis.

Activity in vitro of Rifabutin, FeE 22807, Rifapentine, and Rifampin against Mycobacterium microti and M. tuberculosis and Their Penetration into

D. Mitchison, J. Dhillon, 1992 .

Effects of recombinant interferon-gamma and chemotherapy with isoniazid and rifampicin on infections of mouse peritoneal macrophages with Listeria monocytogenes and Mycobacterium microti in vitro.

D. Mitchison, D. Lowrie, M. Khor, 1986, British journal of experimental pathology.

Serial counts of Mycobacterium tuberculosis in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis

D. Mitchison, R. Brindle, J. Odhiambo, 2001, BMC pulmonary medicine.

Examination of operation specimens from patients with spinal tuberculosis for tubercle bacilli.

D. Mitchison, J. Darbyshire, B. Allen, 1983, Journal of clinical pathology.

Effect of pyridoxine on vitamin B6 concentrations and glutamic-oxaloacetic transaminase activity in whole blood of tuberculous patients receiving high-dosage isoniazid.

D. Mitchison, S. Radhakrishna, J. Selkon, 1967, Bulletin of the World Health Organization.

Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling.

S. Waddell, P. Butcher, D. Mitchison, 2010, Future medicinal chemistry.

Turning intermittent regimens into daily regimens using blister-packs. An exploration in murine tuberculosis.

D. Mitchison, J. Dickinson, A. Guy, 1993, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Bioavailability of rifampin in experimental murine tuberculosis

D. Mitchison, J. Dickinson, A. Guy, 1992, Antimicrobial Agents and Chemotherapy.

Intermittent Dosage in the Treatment of Pulmonary Tuberculosis with Streptomycin

D. Mitchison, P. Armitage, J. Crofton, 1950, British medical journal.

Basic Concepts in the Chemotherapy of Tuberculosis

D. Mitchison, 1998 .

Tuberculosis in patients having dialysis.

D. Mitchison, G. Ellard, 1980, British medical journal.

Studies on the treatment of experimental tuberculosis of the guinea pig with intermittent doses of isoniazid.

D. Mitchison, V. Aber, J. Dickinson, 1973, Tubercle.

Observations in vitro on the suitability of pyrazinamide for intermittent chemotherapy of tuberculosis.

D. Mitchison, J. Dickinson, 1970, Tubercle.

Bactericidal activity in vitro and in the guinea-pig of isoniazid, rifampicin and ethambutol.

D. Mitchison, J. Dickinson, 1976, Tubercle.

In vitro activity of new rifamycins against rifampicin-resistant M. tuberculosis and MAIS-complex mycobacteria.

D. Mitchison, J. Dickinson, 1987, Tubercle.

Examination of smears for tubercle bacilli by fluorescence microscopy.

D. Mitchison, S. Radhakrishna, E. Holst, 1959, The Indian journal of medical research.

A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.

D. Mitchison, R. Rustomjee, G. Davies, 2008, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial

M. Pagano, C. Contreras, R. Calderón, 2016, BMC Infectious Diseases.

Selective Kirchner medium in the culture of specimens other than sputum for mycobacteria.

D. Mitchison, B. Allen, D. Manickavasagar, 1983, Journal of clinical pathology.

Selective media in the isolation of tubercle bacilli from tissues

D. Mitchison, B. Allen, R. A. Lambert, 1973, Journal of clinical pathology.

The chemotherapy of tuberculosis: past, present and future.

D. Mitchison, G. Davies, D Mitchison, 2012, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Bacteriological aspects of the second national survey of primary drug resistance in pulmonary tuberculosis, 1963.

D. Mitchison, R. Tall, M. J. Lefford, 1966, Tubercle.

The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis.

M. Wootton, D. Mitchison, D. De Wit, 1995, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Natural sensitivity of M. tuberculosis to thiacetazone.

D. Mitchison, 1968, Tubercle.

Standard smears for grading the content of acid-fast bacilli in sputum.

D. Mitchison, 1966, Tubercle.

VIRULENCE IN THE GUINEA-PIG AND SENSITIVITY TO PAS AND THIACETAZONE OF TUBERCLE BACILLI FROM SOUTH INDIAN PATIENTS WITH PULMONARY TUBERCULOSIS.

D. Mitchison, J. Selkon, S. Joseph, 1964, Tubercle.

COMPARISON OF THE SENSITIVITY TO THIACETAZONE OF TUBERCLE BACILLI FROM PATIENTS IN BRITAIN, EAST AFRICA, SOUTH INDIA AND HONG KONG.

D. Mitchison, J. Lloyd, 1964, Tubercle.

INFLUENCE OF PRETREATMENT BACTERIAL RESISTANCE TO ISONIAZID, THIACETAZONE OR PAS ON THE RESPONSE TO CHEMOTHERAPY OF AFRICAN PATIENTS WITH PULMONARY TUBERCULOSIS.

D. Mitchison, R. Tall, 1963 .

THE RESPONSE TO TREATMENT WITH THIACETAZONE OF GUINEA-PIGS AND MICE INFECTED WITH TUBERCLE BACILLI OBTAINED FROM UNTREATED AFRICAN PATIENTS.

S. Bushby, D. Mitchison, J. Dickinson, 1963, Tubercle.

Bacteriological aspects of a survey of the incidence of drug-resistant tubercle bacilli among untreated patients.

D. Mitchison, J. Selkon, 1957, Tubercle.

DNA analysis demonstrates that mycococcus forms are not mycobacteria.

D. Mitchison, D. De Wit, 1993, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

The sensitivity to thiacetazone and para-aminosalicylic acid and the virulence in the guinea pig of East African strains of Mycobacterium tuberculosis.

D. Mitchison, J. Dickinson, M. J. Lefford, 1969, Tubercle.

Primary drug resistance in pulmonary tuberculosis in Great Britain: second national survey, 1963.

A. Miller, D. Mitchison, W. Fox, 1966, Tubercle.

Response of patients infected with isoniazid-resistant tubercle bacilli to treatment with isoniazid plus PAS or isoniazid alone.

D. Mitchison, W. Fox, S. Radhakrishna, 1961, Bulletin of the World Health Organization.

Atypical mycobacteria and drug-resistant tubercle bacilli isolated during a survey of untreated patients with pulmonary tuberculosis.

D. Mitchison, J. Selkon, 1959, Tubercle.

Solid and liquid medium tests of streptomycin sensitivity of Mycobacterium tuberculosis.

D. Mitchison, J. Selkon, A. Wallace, 1958, Tubercle.

Isoniazid-resistant strains of tubercle bacili; their development and stability.

S. Bushby, D. Mitchison, M. Barnett, 1953, Lancet.

Role of lipid content and hydrogen peroxide susceptibility in determining the guinea-pig virulence of Mycobacterium tuberculosis.

D. Mitchison, B. Allen, V. Aber, 1982, British journal of experimental pathology.

The correlation of bacteriophage types of Mycobacterium tuberculosis with guinea-pig virulence and in vitro-indicators of virulence.

D. Mitchison, B. Allen, V. Aber, 1978, Journal of general microbiology.

The virulence in the guinea-pig of tubercle bacilli isolated before treatment from South Indian patients with pulmonary tuberculosis. I. Homogeneity of the investigation and a critique of the virulence test.

D. Mitchison, J. Wallace, S. Radhakrishna, 1961, Bulletin of the World Health Organization.

VIRULENCE IN THE GUINEA-PIG AND SUSCEPTIBLITY TO HYDROGEN PEROXIDE OF ISONIAZID-SENSITIVE TUBERCLE BACILLI FROM SOUTH INDIAN PATIENTS.

D. Mitchison, J. Selkon, S. P. Tripathy, 1964, Tubercle.

THE VIRULENCE OF TUBERCLE BACILLI FROM PATIENTS WITH PULMONARY TUBERCULOSIS IN INDIA AND OTHER COUNTRIES.

D. Mitchison, 1964, Bulletin of the International Union against Tuberculosis.

The virulence in the guinea-pig of tubercle bacilli isolated before treatment from South Indian patients with pulmonary tuberculosis. 2. Comparison with virulence of tubercle bacilli from British patients.

D. Mitchison, J. Selkon, P. Somasundaram, 1961, Bulletin of the World Health Organization.

The susceptibility to hydrogen peroxide of Indian and British isoniazid-sensitive and isoniazid-resistant tubercle bacilli

D. Mitchison, J. Selkon, T. Subbaiah, 1960 .

The contribution of hydrogen peroxide resistance to virulence of Mycobacterium tuberculosis during the first six days after intravenous infection of normal and BCG-vaccinated guinea-pigs.

D. Mitchison, V. Aber, P. Jackett, 1981, British journal of experimental pathology.

Short-term intermittent chemotherapy of experimental tuberculosis in the guinea pig

D. Mitchison, J. Dickinson, 1966 .

THE VIRULENCE IN THE GUINEA-PIG OF TUBERCLE BACILLI FROM PATIENTS WITH PULMONARY TUBERCULOSIS IN HONG KONG.

D. Mitchison, J. Dickinson, J. Lloyd, 1963, Tubercle.

Geographic distribution of bacteriophage types of Mycobacterium tuberculosis.

J. Bates, D. Mitchison, 1969, The American review of respiratory disease.

The virulence in the guinea-pig of tubercle bacilli isolated before treatment from South Indian patients with pulmonary tuberculosis. 3. Virulence related to pretreatment status of disease and to response to chemotherapy.

D. Mitchison, J. Wallace, W. Fox, 1961, Bulletin of the World Health Organization.

Regional variation in the guinea-pig virulence and other characteristics of tubercle bacilli

D. Mitchison, 2005, Beiträge zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten.

The consistency of the virulence in the guinea-pig of tubercle bacilli isolated on different occasions from South India patients before treatment

D. Mitchison, S. Radhakrishna, J. Selkon, 1961 .

Viable counting of Mycobacterium tuberculosis in a silica gel medium.

D. Mitchison, J. Selkon, 1957, Journal of general microbiology.

Estimating drug-dosage regimens.

D. Mitchison, W. Fox, 1969, The Lancet.

In vitro and in vivo studies to assess the suitability of antituberculous drugs for use in intermittent chemotherapy regimens.

D. Mitchison, J. Dickinson, 1968, Tubercle.

Comparison of methods for testing the sensitivity of Mycobacterium tuberculosis to ethionamide.

D. Mitchison, M. J. Lefford, 1966, Tubercle.

The virulence in the guinea-pig of isoniazid-sensitive tubercle bacilli isolated from South Indian patients before treatment and after three months of chemotherapy.

D. Mitchison, S. Radhakrishna, J. Selkon, 1961, Bulletin of the World Health Organization.

A comparison of the sensitivity to p-aminosalicylic acid of tubercle bacilli from South Indian and British patients.

D. Mitchison, S. Radhakrishna, J. Selkon, 1960, Bulletin of the World Health Organization.

THE EPIDEMIOLOGY OF TUBERCLE BACILLI.

D. Mitchison, 1963, The Scientific basis of medicine annual reviews.

The virulence of South Indian tubercle bacilli in mice and guinea-pigs infected by the intravenous route.

P. Gangadharam, D. Mitchison, R. Rees, 1961, Tubercle.

Bacteriological mechanisms in recent controlled chemotherapy studies.

D. Mitchison, 1970, Bulletin of the International Union against Tuberculosis.

SERIES ''CONTROVERSIAL ISSUES IN TUBERCULOSIS'' Edited by A. Torres and J. Caminero Number 3 in this Series Drug resistance in tuberculosis

D. Mitchison, Cranmer Terrace, 2005 .

Response to treatment with isoniazid plus PAS of tuberculous patients with primary isoniazid resistance.

D. Mitchison, A. Narayana, S. P. Tripathy, 1969, Tubercle.

Pharmacology of some slow-release preparations of isoniazid of potential use in intermittent treatment of tuberculosis.

P. T. Gammon, D. Mitchison, S. Lakshminarayan, 1972, Lancet.

Activity in vitro of rifabutin, FCE 22807, rifapentine, and rifampin against Mycobacterium microti and M. tuberculosis and their penetration into mouse peritoneal macrophages.

D. Mitchison, J. Dhillon, 1992, The American review of respiratory disease.

Comparison of Chinese and Western rifapentines and improvement of bioavailability by prior taking of various meals.

D. Mitchison, W. Yew, B. Allen, 1994, International journal of antimicrobial agents.

Activity of two long-acting rifamycins, rifapentine and FCE 22807, in experimental murine tuberculosis.

D. Mitchison, T. Ng, J. Dhillon, 1992, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Studies of serial plasma Isoniazid concentrations with different doses of a slow-release preparation of Isoniazid.

N. G. Nair, D. Mitchison, G. Sarma, 1975, Tubercle.

Influence of BCG-induced immunity on the bactericidal activity of isoniazid and rifampicin in experimental tuberculosis of the mouse and guinea-pig.

D. Mitchison, J. Dhillon, 1989, British journal of experimental pathology.

The hepatic toxicity of isoniazid among rapid and slow acetylators of the drug.

D. Girling, D. Mitchison, A. Nunn, 1978, The American review of respiratory disease.

Assessment of the Efficacy of New Anti-Tuberculosis Drugs.

D. Mitchison, G. Davies, 2009, The open infectious diseases journal.

Bacteriology of Tuberculosis

D. Mitchison, 1974, Tropical doctor.

Slide culture sensitivity tests.

D. Mitchison, B. Allen, J. Dickinson, 1989, Tubercle.

Tests for streptomycin sensitivity of tubercle bacilli in tween 80 albumin liquid medium.

D. Mitchison, 1949, Lancet.

Bactericidal Activity of Moxifloxacin on Exponential and Stationary Phase Cultures of Mycobacterium tuberculosis

P. Venkatesan, D. Mitchison, S. Sulochana, 2009, Journal of chemotherapy.

New antibacterial drugs for the treatment of mycobacterial disease in man.

D. Mitchison, J. Grosset, G. Ellard, 1988, British medical bulletin.

The effect of pulsed exposures to rifampin on the uptake of uridine- 14 C by Mycobacterium tuberculosis.

D. Mitchison, P. Jackett, J. Dickinson, 1972, The American review of respiratory disease.

Application of DNA fingerprinting with IS986 to sequential mycobacterial isolates obtained from pulmonary tuberculosis patients in Hong Kong before, during and after short-course chemotherapy.

D. Mitchison, B. Allen, S. Das, 1993, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Bactericidal Action of Gatifloxacin, Rifampin, and Isoniazid on Logarithmic- and Stationary-Phase Cultures of Mycobacterium tuberculosis

P. Venkatesan, D. Mitchison, S. Sulochana, 2005, Antimicrobial Agents and Chemotherapy.

Persister populations of Mycobacterium tuberculosis in sputum that grow in liquid but not on solid culture media.

D. Mitchison, J. Dhillon, P. Fourie, 2014, The Journal of antimicrobial chemotherapy.

An effective method of RNA extraction from bacteria refractory to disruption, including mycobacteria.

P. Butcher, D. Mitchison, J. Mangan, 1997, Nucleic acids research.

Predictive in vitro models of the sterilizing activity of anti-tuberculosis drugs.

D. Mitchison, A. Coates, Anthony R M Coates, 2004, Current pharmaceutical design.

Metronidazole has no antibacterial effect in Cornell model murine tuberculosis.

D. Mitchison, A. Coates, B. Allen, 1998, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

The search for new sterilizing anti-tuberculosis drugs.

D. Mitchison, Denis A Mitchison, 2004, Frontiers in bioscience : a journal and virtual library.

The early bactericidal activity of a low-clearance liposomal amikacin in pulmonary tuberculosis.

D. Mitchison, P. Donald, F. Sirgel, 2001, The Journal of antimicrobial chemotherapy.

Use of the Phoenix system for bacteriology

D. Mitchison, J. Darrell, J. Perry, 1983, Journal of clinical pathology.

Detection of mRNA Transcripts and Active Transcription in Persistent Mycobacterium tuberculosisInduced by Exposure to Rifampin or Pyrazinamide

P. Butcher, D. Mitchison, Yanmin Hu, 2000, Journal of bacteriology.

In vitro observations on the suitability of new rifamycins for the intermittent chemotherapy of tuberculosis.

D. Mitchison, J. Dickinson, 1987, Tubercle.

Bactericidal activity of streptomycin and isoniazid in combination with p-aminosalicylic acid against Mycobacterium tuberculosis.

D. Mitchison, B. Singh, 1955, Journal of general microbiology.

Pharmacokinetic/pharmacodynamic parameters and the choice of high-dosage rifamycins.

D. Mitchison, 2012, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Quality control in tuberculosis bacteriology. 2. The origin of isolated positive cultures from the sputum of patients in four studies of short course chemotherapy in Africa.

D. Mitchison, A. Nunn, S. Byfield, 1980, Tubercle.

Rifabutin in the treatment of newly diagnosed pulmonary tuberculosis.

D. Mitchison, 1995, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

The bactericidal activities of combinations of streptomycin, isoniazid, p-aminosalicylic acid (PAS), oxytetracycline (terramycin) and viomycin against Mycobacterium tuberculosis.

D. Mitchison, B. Singh, 1955, Journal of general microbiology.

Contradictory Results with High-Dosage Rifamycin in Mice and Humans

D. Mitchison, Yanmin Hu, A. Coates, 2013, Antimicrobial Agents and Chemotherapy.

Mycobacterium tuberculosis from chronic murine infections that grows in liquid but not on solid medium

D. Mitchison, D. Lowrie, J. Dhillon, 2004, BMC infectious diseases.

Comparison of machine and manual staining of direct smears for acid-fast bacilli by fluorescence microscopy.

D. T. Rogers, D. Mitchison, V. Aber, 1976, Journal of clinical pathology.

Demonstration of increased anti-mycobacterial activity in peripheral blood monocytes after BCG vaccination in British school children.

J. Poole, D. Mitchison, V. Aber, 1988, Clinical and experimental immunology.

A computer-assisted bacteriology reporting and information system.

D. Mitchison, J. Darrell, R. Mitchison, 1978, Journal of clinical pathology.

Moxifloxacin and Gatifloxacin in an Acid Model of Persistent Mycobacterium tuberculosis

D. Mitchison, S. Sulochana, C. N. Paramasivan, 2006, Journal of chemotherapy.

Reappraisal of the activity of morphazinamide against M. tuberculosis.

D. Mitchison, G. Ellard, T. Bravo, 1975, Tubercle.

A new antituberculosis drug that selectively kills nonmultiplying Mycobacterium tuberculosis.

D. Mitchison, 2008, Cell host & microbe.

Chemotherapy of Tuberculosis: a Bacteriologist's Viewpoint*

D. Mitchison, 1965, British medical journal.

Culture of specimens other than sputum for Mycobacteria

D. Mitchison, V. Aber, 1974, Journal of Clinical Pathology.

Problems of drug resistance.

D. Mitchison, 1954, British medical bulletin.

Examination of sputum by smear and culture in case-finding.

D. Mitchison, 1968, Bulletin of the International Union against Tuberculosis.

Detection of rifampicin in urine by a simple microbiological assay.

A. Miller, D. Mitchison, B. Allen, 1970, Tubercle.

Sensitive microbiological method for the detection of rifampicin in urine.

D. Mitchison, A. Nunn, B. Allen, 1974, Tubercle.

Assay of rifampicin in serum

D. Mitchison, B. Allen, V. Aber, 1974, Journal of clinical pathology.

Computer-aided procedures in a multi-centre co-operative controlled clinical trial in pulmonary tuberculosis.

D. Mitchison, A. Nunn, R. Tall, 1971, Tubercle.

Isoniazid activity is terminated by bacterial persistence.

D. Mitchison, A. Jindani, Frederik Sirgel, 2007, The Journal of infectious diseases.

Early bactericidal activity and sterilizing activity of ciprofloxacin in pulmonary tuberculosis.

D. Mitchison, 1995, American journal of respiratory and critical care medicine.

Mechanisms of Pyrazinamide Action and Resistance

Ying Zhang, W. Shi, Wenhong Zhang, 2014, Microbiology spectrum.

Activity of Pyrazinamide in the Guinea Pig Model of Tuberculosis

D. Mitchison, 2010, Antimicrobial Agents and Chemotherapy.

HspX knock-out in Mycobacterium tuberculosis leads to shorter antibiotic treatment and lower relapse rate in a mouse model--a potential novel therapeutic target.

K. Oravcová, S. Gillespie, D. Mitchison, 2015, Tuberculosis.

Role of isoniazid in once-weekly rifapentine treatment of pulmonary tuberculosis.

D. Mitchison, 2003, American journal of respiratory and critical care medicine.

Experimental infective pneumoconiosis. III. Coal-mine dust and isoniazid-resistant tubercle bacilli of moderate virulence.

D. Mitchison, C. Harrison, E. King, 1955, British journal of experimental pathology.

Experimental infective pneumoconiosis.

D. Mitchison, C. Harrison, G. P. Mohanty, 1958 .

Rifapentine and isoniazid in the continuation phase of a 6-month regimen. Interim report: no activity of isoniazid in the continuation phase.

D. Mitchison, C. Tam, H. Al-Ghusein, 2000, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Experimental models of tuberculosis: can we trust the mouse?

D. Mitchison, K. Chang, 2009, American journal of respiratory and critical care medicine.

Bacteriological aspects of mycobacterial infections.

D. Mitchison, 1972, British medical journal.

The early bactericidal activity of streptomycin.

C. Doré, D. Mitchison, P. Donald, 2002, The International Journal of Tuberculosis and Lung Disease.