J. Mestecky

B. Julian, J. Novak, J. Mestecky, 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

IgA-Associated Diseases

L. Hammarström, J. Mestecky, 2007 .

Polyethylene glycol precipitates of serum contain a large proportion of uncomplexed immunoglobulins and C3.

J. Mestecky, R. Schrohenloher, P. Crowley-Nowick, 1996, Immunological investigations.

Progress in the pathogenesis of IgA nephropathy.

B. Julian, J. Novak, J. Mestecky, 1999, Advances in nephrology from the Necker Hospital.

Ultrastructural studies of human lymphoid cells. mu and J chain expression as a function of B cell differentiation

M. Cooper, J. Mestecky, Z. Moldoveanu, 1983, The Journal of experimental medicine.

Carbohydrate-mediated clearance of secretory IgA from the circulation.

J. Mestecky, M. Tomana, R. Kulhavy, 1985, Molecular immunology.

IgA-containing immune complexes in the urine of IgA nephropathy patients.

B. Julian, J. Novak, J. Mestecky, 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Structural heterogeneity of glycans in IgA molecules: Implications for IgA nephropathy

J. Mestecky, M. Tomana, 1997 .

Binding of IgA to erythrocytes from patients with IgA nephropathy.

C. Czerkinsky, J. Mestecky, Z. Moldoveanu, 1988, Clinical immunology and immunopathology.

Immunobiology of IgA.

J. Mestecky, 1988, American journal of kidney diseases : the official journal of the National Kidney Foundation.

IgA-mediated clearance and tissue deposition of dinitrophenylated human serum albumin at various DNP:HSA ratios.

J. M. Epps, J. Mestecky, J. Phillips, 1988, Molecular immunology.

Detection of food antigen-specific IgA immune complexes in human sera.

B. Julian, J. Mestecky, M. Russell, 1987, Advances in experimental medicine and biology.

Properties of IgA myeloma proteins isolated rom sera of patients with the hyperviscosity syndrome.

J. Mestecky, M. Tomana, R. Kulhavy, 1977, The Journal of laboratory and clinical medicine.

IgA rheumatoid factor synthesis by dissociated synovial cells. Characterization and relationship to IgM rheumatoid factor synthesis.

J. Mestecky, R. Schrohenloher, S. Crago, 1985, Arthritis and rheumatism.

Historical Aspects of Mucosal Immunology

J. Mestecky, 2005 .

Role of serum IgA. Hepatobiliary transport of circulating antigen

J. Mestecky, M. Russell, T. A. Brown, 1981, The Journal of experimental medicine.

IgA‐MEDIATED HEPATOBILIARY CLEARANCE OF BACTERIAL ANTIGENS *

J. Mestecky, M. Russell, T. A. Brown, 1983 .

Analysis of the hepatobiliary transport of IgA with monoclonal anti-idiotype and anti-allotype antibodies.

J. M. Epps, J. Kearney, J. Mestecky, 1986, Molecular immunology.

Secretory component of epithelial cells is a surface receptor for polymeric immunoglobulins

J. Mestecky, S. Crago, S. Prince, 1978, The Journal of experimental medicine.

Interactions of cell-surface galactosyltransferase with immunoglobulins.

J. Mestecky, Z. Moldoveanu, J. Zikán, 1993, Molecular immunology.

Selective hepatobiliary transport of human polymeric IgA in mice.

J. Mestecky, M. Russell, T. A. Brown, 1984, Molecular immunology.

Expression of the recombinant human immunoglobulin J chain in Escherichia coli.

L. DeLucas, J. Symerský, J. Novak, 2000, Molecular Immunology.

Role of hepatocytes in the uptake of IgA and IgA-containing immune complexes in mice.

J. M. Epps, K. Komiyama, J. Mestecky, 1988, Molecular immunology.

Secretory immunoglobulin A carries oligosaccharide receptors for Escherichia coli type 1 fimbrial lectin

J. Mestecky, A. Kobata, T. Endo, 1990, Infection and immunity.

IgA-induced eosinophil degranulation.

R. Kyle, J. Mestecky, G. Gleich, 1989, Journal of immunology.

Properties of immunoglobulin A in serum of individuals with liver diseases and in hepatic bile.

J. Mestecky, S. Prince, W. Kutteh, 1982, Gastroenterology.

Lectin Receptors on IgA Isotypes

C. Svanborg, J. Mestecky, A. Wold, 1994, Scandinavian journal of immunology.

Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study.

B. Julian, J. Novak, Hitoshi Suzuki, 2010, Biochemistry.

IgA Immune-Complex

J. Novak, J. Mestecky, 2009 .

Journal ClubAuthors' reply:

B. Julian, J. Novak, J. Mestecky, 2000 .

Immunization of humans with polysaccharide vaccines induces systemic, predominantly polymeric IgA2-subclass antibody responses.

J. Mcghee, H. Kiyono, J. Mestecky, 1990, Journal of immunology.

Evaluation of monoclonal antibodies with specificity for human IgA, IgA subclasses and allotypes and secretory component. Results of an IUIS/WHO collaborative study.

G. Carlone, R. Jefferis, M. Goodall, 1996, Journal of immunological methods.

Normal human sera contain antibodies directed at Fab of IgA.

C. Czerkinsky, J. Mestecky, R. Montgomery, 1987, Journal of immunology.

Immunoglobulin A (IgA).

M. Kilian, J. Mestecky, 1985, Methods in enzymology.

IgA1 proteases from Haemophilus influenzae, Streptococcus pneumoniae, Neisseria meningitidis, and Streptococcus sanguis: comparative immunochemical studies.

M. Kilian, J. Mestecky, W. Butler, 1980, Journal of immunology.

Biosynthesis of J-chain in human lymphoid cells producing immunoglobulins of various isotypes.

J. Mestecky, Z. Moldoveanu, S. Prince, 1983, Molecular immunology.

Comparative Studies of the Biological Properties of Human IgA Subclasses

J. Mcghee, H. Kiyono, J. Mestecky, 1989 .

Chapter 9 – Mucosal Immunoglobulins

M. Kerr, J. Woof, J. Mestecky, 2005 .

Role of IL-6 in human antigen-specific and polyclonal IgA responses.

J. Mcghee, H. Kiyono, J. Mestecky, 1991, Advances in experimental medicine and biology.

Regulation of IgA synthesis and immune response by T cells and interleukins

J. Mcghee, H. Kiyono, C. Elson, 1989, Journal of Clinical Immunology.

Urethral Cytokine and Immune Responses inChlamydia trachomatis-Infected Males

J. Mestecky, M. Russell, E. Hook, 2001, Infection and Immunity.

A novel two colour ELISPOT assay. I. Simultaneous detection of distinct types of antibody-secreting cells.

C. Czerkinsky, J. Mestecky, Z. Moldoveanu, 1988, Journal of immunological methods.

Antibody-dependent passive protection of mucosal surfaces

J. Mestecky, 2021, Human vaccines & immunotherapeutics.

Structural differences among serum IgA proteins of chimpanzee, rhesus monkey and rat origin.

J. Mestecky, T. Endo, J. Radl, 1997, Molecular immunology.

Molecular heterogeneity of human IgA antibodies during an immune response

J. Mestecky, M. Russell, Z. Moldoveanu, 1992, Clinical and experimental immunology.

Cellular origins of human polymeric and monomeric IgA: enumeration of single cells secreting polymeric IgA1 and IgA2 in peripheral blood, bone marrow, spleen, gingiva and synovial tissue

J. Mestecky, Z. Moldoveanu, A. Tarkowski, 1991, Clinical and experimental immunology.

The carbohydrate composition of human myeloma IgA.

J. Mestecky, W. Niedermeier, M. Tomana, 1972, Immunochemistry.

Multiparametric flow cytometry analysis of peripheral blood B cell trafficking differences among Epstein-Barr virus infected and uninfected subpopulations.

P. Hubáček, M. Raška, J. Mestecky, 2019, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.

Molecular characterization of protein Sir, a streptococcal cell surface protein that binds both immunoglobulin A and immunoglobulin G.

G. Lindahl, L. Stenberg, P. O’Toole, 1994, The Journal of biological chemistry.

Immunologic Uniqueness of the Genital Tract: Challenge for Vaccine Development

J. Mestecky, M. Russell, Z. Moldoveanu, 2005, American journal of reproductive immunology.

Mucosal Vaccines: An Overview

J. Mcghee, C. Czerkinsky, J. Mestecky, 2005, Mucosal Immunology.

Chapter 47 – Mucosal Vaccines: An Overview

J. Mestecky, M. Russell, 2005 .

Comparison of systemic and mucosal delivery of 2 canarypox virus vaccines expressing either HIV-1 genes or the gene for rabies virus G protein.

M. McElrath, P. Goepfert, Yuwei Zhu, 2004, The Journal of infectious diseases.

Properties of IgA‐Binding Receptors on Murine T Cells: Relative Importance of FcαR, β‐Galactosyltransferase and Anti‐Secretory Component Reactive Proteins (ASCP)

T. Meyer, M. McGhee, J. Mcghee, 1992 .

Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.

Yusuke Suzuki, B. Julian, J. Novak, 2009, The Journal of clinical investigation.

Precursor B cells transformed by Epstein-Barr virus undergo sterile plasma-cell differentiation: J-chain expression without immunoglobulin.

M. Cooper, C. Grossi, J. Mestecky, 1988, Proceedings of the National Academy of Sciences of the United States of America.

IgA-associated renal diseases: Antibodies to environmental antigens in sera and deposition of immunoglobulins and antigens in glomeruli

B. Julian, J. Mestecky, M. Russell, 2004, Journal of Clinical Immunology.

Intestinal Immunoglobulin A: Role in Host Defense

J. Mestecky, M. Russell, 2003 .

Human and nonhuman primate lymphocytes engrafted into SCID mice reside in unique mesenteric lymphoid structures.

P. Fultz, J. Cummins, J. Mestecky, 1998, Journal of immunology.

Mesenteric Lymphoid Structures Engrafted into SCID Mice Reside in Unique Human and Nonhuman Primate Lymphocytes

P. Fultz, J. Cummins, J. Mestecky, 1998 .

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

S. Tonegawa, J. Mcghee, H. Kiyono, 1996, The Journal of experimental medicine.

Differences in Immune Responses Induced by Oral and Rectal Immunizations with Salmonella typhi Ty21a: Evidence for Compartmentalization within the Common Mucosal Immune System in Humans

R. Alvarez, A. Kantele, S. Michalek, 1998, Infection and Immunity.

Limited Local and Systemic Antibody Responses toNeisseria gonorrhoeae during Uncomplicated Genital Infections

M. Mayo, J. Mestecky, M. Russell, 1999, Infection and Immunity.

Differential homing commitments of antigen-specific T cells after oral or parenteral immunization in humans.

C. Elson, J. Živný, A. Kantele, 1999, Journal of immunology.

IgA antibody-producing cells in peripheral blood after antigen ingestion: evidence for a common mucosal immune system in humans

J. Mcghee, S. Michalek, C. Czerkinsky, 1987 .

Molecular-cellular interactions in the secretory IgA system.

J. Mestecky, S. Crago, S. Prince, 1978, Advances in experimental medicine and biology.

Affinity chromatography of glycopeptides using concanavalin A.

J. Mestecky, R. Schrohenloher, W. Niedermeier, 1976, Analytical biochemistry.

Mucosal immunity: The missing link in comprehending SARS-CoV-2 infection and transmission

J. Mestecky, M. Russell, 2022, Frontiers in Immunology.

Role of nuclear factor-κ B in the expression by tumor necrosis factor-α of the human polymeric immunoglobulin receptor (pIgR ) gene

J. Mestecky, I. Moro, Z. Moldoveanu, 2000, Immunogenetics.

Mucosal immune system of the human genital tract.

P. Fultz, J. Mestecky, 1999, The Journal of infectious diseases.

Immunoglobulin M and Secretory Immunoglobulin A: Presence of a Common Polypeptide Chain Different from Light Chains

J. Mestecky, W. Butler, Jiri Zikan, 1971, Science.

Secretory immune system of the female reproductive tract. II. Local immune system in normal and infected fallopian tube.

J. Mestecky, B. Carr, W. Kutteh, 1990, Fertility and sterility.

Biodegradable microspheres for the delivery of oral vaccines

R. Compans, J. Mestecky, Z. Moldoveanu, 1994 .

Current options for vaccine delivery systems by mucosal routes

R. Compans, S. Michalek, C. Morrow, 1997 .

IgA RHEUMATOID FACTOR: EVIDENCE FOR INDEPENDENT EXPRESSION AT LOCAL SITES OF TISSUE INFLAMMATION *

R. K. Miller, J. Mestecky, R. Schrohenloher, 1983, Annals of the New York Academy of Sciences.

Shared Idiotypes Among Anti‐Albumin Antibodies of Different Species

J. Mestecky, S. Jackson, R. Kulhavy, 1981, Scandinavian journal of immunology.

Production of predominantly polymeric IgA by human peripheral blood lymphocytes stimulated in vitro with mitogens

M. Conley, J. Mestecky, W. Koopman, 1980, The Journal of experimental medicine.

Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women.

L. Lopalco, M. Hoelscher, Yuwei Zhu, 2010, AIDS research and human retroviruses.

Synergistic effect of IL-4 and IFN-gamma on the expression of polymeric Ig receptor (secretory component) and IgA binding by human epithelial cells.

J. Mestecky, Z. Moldoveanu, C. Lue, 1990, Journal of immunology.

Degradation of IgA proteins by Pseudomonas aeruginosa elastase.

J. Mestecky, M. Russell, K. Morihara, 1990, Journal of immunology.

Humoral immune responses to microbial infections in the genital tract.

J. Mestecky, M. Russell, 2002, Microbes and infection.

Mucosal Immunoregulation: IgA Inductive Sites, Isotype-Specific Helper T Cells, Gut LPS Influence, and Subclass Distribution of IgA Antibodies

J. Mcghee, H. Kiyono, S. Michalek, 1985 .

Mechanisms of immune tolerance to food antigens in humans.

C. Elson, J. Živný, J. Mestecky, 2001, Clinical immunology.

Mucosal Immunity in Sexually Transmitted Infections

J. Mestecky, M. Russell, 2018, Diagnostics to Pathogenomics of Sexually Transmitted Infections.

Diminished CD103 (αEβ7) Expression on Resident T Cells from the Female Genital Tract of HIV-Positive Women

M. Saag, P. Goepfert, H. Richter, 2017, Pathogens & immunity.

Local IgA and IgM rheumatoid factor production in autoimmune MRL/lpr mice.

R. Jonsson, J. Mestecky, A. Pitts, 1991, Autoimmunity.

Mucosal immunity in the female reproductive tract: correlation of immunoglobulins, cytokines, and reproductive hormones in human cervical mucus around the time of ovulation.

J. Mestecky, Z. Moldoveanu, W. Kutteh, 1998, AIDS research and human retroviruses.

Mucosal immunity in the female genital tract: relevance to vaccination efforts against the human immunodeficiency virus.

J. Mestecky, S. Jackson, W. Kutteh, 1994, AIDS research and human retroviruses.

Chapter 95 – Mucosal Immunity in the Human Female Reproductive Tract

J. Mestecky, C. Wira, W. Kutteh, 2005 .

A polarized human endometrial cell line that binds and transports polymeric IgA

M. Mulligan, R. Compans, J. Mestecky, 1995, In Vitro Cellular & Developmental Biology - Animal.

Comparative analysis of oral delivery systems for live rotavirus vaccines

R. Compans, Y. Matsuoka, J. Mestecky, 1996 .

Variations in immunoglobulins and IgA subclasses of human uterine cervical secretions around the time of ovulation

J. Mestecky, S. Prince, W. Kutteh, 1996, Clinical and experimental immunology.

Secretory immune system of the female reproductive tract: I. Immunoglobulin and secretory component‐containing cells

K. Hatch, J. Mestecky, W. Kutteh, 1988, Obstetrics and gynecology.

Advances in Mucosal Immunology

S. Michalek, J. Mestecky, H. Tlaskalova-Hogenova, 1995, Advances in Experimental Medicine and Biology.

Systemic immunization with pneumococcal polysaccharide vaccine induces a predominant IgA2 response of peripheral blood lymphocytes and increases of both serum and secretory anti-pneumococcal antibodies.

J. Mestecky, A. Tarkowski, C. Lue, 1988, Journal of immunology.

Diagnostic Significance of Antibodies in Oral Secretions

J. Mestecky, M. Russell, S. Hedges, 2002 .

Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding.

C. Elson, S. Husby, J. Mestecky, 1994, Journal of immunology.

Evaluation of Immunoglobulin A1 (IgA1) Protease and IgA1 Protease-Inhibitory Activity in Human Female Genital Infection with Neisseria gonorrhoeae

J. Mestecky, M. Russell, E. Hook, 1998, Infection and Immunity.

The differences in carbohydrate composition between the subclasses of IgA immunoglobulins.

J. Mestecky, W. Niedermeier, M. Tomana, 1976, Immunochemistry.

Cloning and expression of the chicken immunoglobulin joining (J)-chain cDNA

C. H. Chen, K. Komiyama, J. Mestecky, 2000, Immunogenetics.

Human colostral cells. I. Separation and characterization.

J. Mcghee, T. Pretlow, J. Mestecky, 1979, Clinical and experimental immunology.

Intestinal IgA System

J. Mcghee, C. Elson, J. Mestecky, 1988, Immunology and Allergy Clinics of North America.

Elimination of intestinally absorbed antigen into the bile by IgA.

J. Mestecky, M. Russell, T. A. Brown, 1984, Journal of immunology.

Immunoglobulin A-mediated hepatobiliary transport constitutes a natural pathway for disposing of bacterial antigens

J. Mestecky, M. Russell, T. A. Brown, 1983, Infection and immunity.

Interaction of specific and innate factors of immunity: IgA enhances the antimicrobial effect of the lactoperoxidase system against Streptococcus mutans.

J. Mestecky, Z. Moldoveanu, K. Pruitt, 1982, Journal of immunology.

Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women

P. Goepfert, J. Mestecky, Z. Moldoveanu, 2012, The open AIDS journal.

Prospects for human mucosal vaccines.

J. Mcghee, J. Mestecky, 1992, Advances in experimental medicine and biology.

Targeting and controlled release of antigens for the effective induction of secretory antibody responses.

J. Eldridge, J. Mestecky, 1991, Current opinion in immunology.

Antibodies to mouse mammary tumor virus‐related antigen in sera of patients with breast carcinoma

J. Mestecky, W. Niedermeier, M. Tomana, 1981, Cancer.

Antibodies to human native and denatured collagens in synovial fluids of patients with rheumatoid arthritis.

E. J. Miller, J. Mestecky, J. Bennett, 1976, Clinical immunology and immunopathology.

Defense mechanisms involving Fc-dependent functions of immunoglobulin A and their subversion by bacterial immunoglobulin A proteases.

M. Kilian, J. Mestecky, M. Russell, 1988, Microbiological reviews.

HIV-1/SIV Humoral Responses in External Secretions

G. Tomaras, J. Mestecky, Jiri Mestecky and Georgia D. Tomaras, 2019, Current Immunology Reviews.

Mucosal Immunity in the Genital Tract: Prospects for Vaccines Against Sexually Transmitted Diseases—A Review

J. Mestecky, M. Russell, E. Hook, 1999, American journal of reproductive immunology.

Oral immunization: past and present.

J. Mcghee, J. Mestecky, 1989, Current topics in microbiology and immunology.

Induction of the mucosal immune response.

J. Mestecky, M. Russell, 1988, Reviews of infectious diseases.

Genital secretory immune response to chronic simian immunodeficiency virus (SIV) infection: a comparison between intravenously and genitally inoculated rhesus macaques

J. Mcghee, H. Kiyono, P. Marx, 1992, Clinical and experimental immunology.

Nanosecond fluorescence spectroscopy of human immunoglobulin A.

J. Mestecky, H. Cheung, B. M. Liu, 1981, Biochemistry.

Interference of secretory immunoglobulin A with sorption of oral bacteria to hydroxyapatite

M. Kilian, J. Mestecky, K. Roland, 1981, Infection and immunity.

Studies on human secretory immunoglobulin A. V. Trypsin hydrolysis at elevated temperatures.

J. Mestecky, R. Schrohenloher, J. Zikán, 1972, Immunochemistry.

Studies on human secretory immunoglobulin A. II. Subunit structure.

J. Mestecky, F. W. Kraus, R. Kulhavy, 1972, Journal of immunology.

Systemic immunization for the induction of IgA responses.

J. Mcghee, H. Kiyono, J. Prchal, 1989, Current topics in microbiology and immunology.

IgA subclass responses to lipopolysaccharide in humans.

J. Mcghee, S. Michalek, J. Mestecky, 1987, Advances in experimental medicine and biology.

Antisperm antibodies in infertile women: subclass distribution of immunoglobulin (Ig) A antibodies and removal of IgA sperm-bound antibodies with a specific IgA1 protease.

M. Kilian, J. Mestecky, W. Kutteh, 1995, Fertility and sterility.

Antisperm Antibodies (ASAs) in Infertile Males: Subclass Distribution of IgA Antibodies and the Effect of an IgA1 Protease on Sperm‐Bound Antibodies

M. Kilian, J. Mestecky, E. Byrd, 1994, American journal of reproductive immunology.

Selective induction of an immune response in human external secretions by ingestion of bacterial antigen.

J. Mcghee, S. Michalek, J. Mestecky, 1978, The Journal of clinical investigation.

Influenza Virus-Infected Epithelial Cells Present Viral Antigens to Antigen-Specific CD8+ Cytotoxic T Lymphocytes

J. Mcghee, H. Kiyono, J. Mestecky, 1998, Journal of Virology.

Localization of IgA and IgM in human colostral elements using immunoelectron microscopy

J. Mestecky, I. Moro, S. Crago, 1983, Journal of Clinical Immunology.

Immunohistochemical localization of amylase, lysozyme and immunoglobulins in the human parotid gland.

J. Mestecky, F. W. Kraus, 1971, Archives of oral biology.

Early expression of human J chain and mu chain gene in the fetal liver.

J. Mestecky, L. Chu, I. Moro, 1993, Cell structure and function.

Human peritoneal B‐1 cells and the influence of continuous ambulatory peritoneal dialysis on peritoneal and peripheral blood mononuclear cell (PBMC) composition and immunoglobulin levels

B. Julian, A. Kantele, J. Mestecky, 1997, Clinical and experimental immunology.

Induction of Tolerance in Humans.

C. Elson, S. Husby, J. Mestecky, 1996 .

Strategies of immunization against mucosal infections.

J. Mestecky, M. Russell, Z. Moldoveanu, 2000, Vaccine.

J-chain expression in human cells producing IgG subclasses.

J. Mestecky, P. Haber, 1985, Cellular immunology.

Isotype-specific immunoregulation; characterization and function of Fc receptors on T-T hybridomas which produce murine IgA-binding factor.

J. Mcghee, H. Kiyono, C. Grossi, 1986, Journal of immunology.

Gamma Interferon Is Not Required for Mucosal Cytotoxic T-Lymphocyte Responses or Heterosubtypic Immunity to Influenza A Virus Infection in Mice

J. Mcghee, J. Mestecky, H. Nguyen, 2000, Journal of Virology.

Menstrual Blood as a Potential Source of Endometrial Derived CD3+ T Cells

P. Goepfert, H. Richter, Z. Hel, 2011, PloS one.

Local production of IgA- and IgM-rheumatoid factors in adult periodontal disease

J. Mestecky, A. Tarkowski, W. Koopman, 1989, Journal of Clinical Immunology.

Inhibition of the pokeweed mitogen-induced response of normal peripheral blood lymphocytes by humoral components of colostrum.

J. Mestecky, S. Crago, S. Prince, 1981, Clinical and experimental immunology.

Transforming growth factor-β enhances secretory component and major histocompatibility complex class I antigen expression on rat IEC-6 intestinal epithelial cells

J. Mcghee, J. Eldridge, J. Mestecky, 1991 .

Characterization of IgA1, IgA2 and secretory IgA carbohydrate chains using plant lectins.

C. Svanborg, J. Mestecky, L. Hanson, 1995, Advances in experimental medicine and biology.

Evidence for a Common Mucosal Immune System in Humans

J. Mcghee, S. Michalek, C. Czerkinsky, 1985 .

Primary antibody response studied by using inhibitors of nucleic acid synthesis

J. Mestecky, J. Šterzl, L. Jarošková, 2008, Folia Microbiologica.

Oral tolerance in humans: T cell but not B cell tolerance to a soluble protein antigen.

C. Elson, S. Husby, J. Mestecky, 1995, Advances in experimental medicine and biology.

Intestinal IgA: novel views on its function in the defence of the largest mucosal surface

C. Elson, J. Mestecky, M. Russell, 1999, Gut.

Inhibition of natural killer cell activity by IgA.

K. Komiyama, J. Mestecky, I. Moro, 1986, Cellular immunology.

ANTIBACTERIAL PROPERTIES OF MILK: IgA‐PEROXIDASE‐LACTOFERRIN INTERACTIONS

J. Mestecky, Z. Moldoveanu, K. Pruitt, 1983 .

Enteric immunization reveals a T cell network for IgA responses and suggests that humans possess a common mucosal immune system

J. Mcghee, H. Kiyono, S. Michalek, 2004, Antonie van Leeuwenhoek.

In defense of mucosal surfaces. Development of novel vaccines for IgA responses protective at the portals of entry of microbial pathogens.

J. Mcghee, J. Mestecky, 1990, Infectious disease clinics of North America.

Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the Cholera toxin B subunit

J. Mestecky, M. Russell, Z. Moldoveanu, 1996, Infection and immunity.

toxin B subunit . with a bacterial protein antigen and the Cholera responses in monkeys immunized intranasally Salivary , nasal , genital , and systemic antibody

S. Michalek, J. Mestecky, M. Russell, 1996 .

Liposomes and conjugate vaccines for antigen delivery and induction of mucosal immune responses.

S. Michalek, J. Mestecky, M. Russell, 1992, Advances in experimental medicine and biology.

Heterogeneity of binding of monoclonal IgA to staphylococcal protein A is related to the IgA polymerization state.

J. Mestecky, Z. Moldoveanu, J. Zikán, 1987, Immunology letters.

Peyer's patch B cells with memory cell characteristics undergo terminal differentiation within 24 hours in response to interleukin-6.

J. Mcghee, H. Kiyono, J. Eldridge, 1991, Cytokine.

Prevention ofStreptococcus mutans colonization by salivary IgA antibodies

J. Mcghee, S. Michalek, J. Mestecky, 2004, Journal of Clinical Immunology.

Humoral Immune Response to Keyhole Limpet Haemocyanin, the Protein Carrier in Cancer Vaccines

C. Elson, J. Živný, A. Kantele, 2011, Clinical & developmental immunology.

Induction of specific immune responses in the genital tract of women after oral or rectal immunization and rectal boosting with Salmonella typhi Ty 21a vaccine.

A. Kantele, J. Mestecky, Z. Moldoveanu, 2001, Journal of reproductive immunology.

Cytokine-induced immunoglobulin production in primary IgA nephropathy.

B. Julian, J. Hermans, J. Mestecky, 1992, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Transforming growth factor-β inhibits the production of IgG, IgM, and IgA in human lymphocyte cultures

J. Mestecky, S. Jackson, R. Kulhavy, 1992 .

Urinary Immunoglobulins in Healthy Individuals and Children with Acute Pyelonephritis

J. Mestecky, S. Mårild, S. Prince, 1985, Scandinavian journal of immunology.

Induction of mucosal immune responses in the human genital tract.

J. Mestecky, M. Russell, 2000, FEMS immunology and medical microbiology.

Heterogeneity of IgG Glycosylation in Adult Periodontal Disease

J. Novak, J. Mestecky, M. Tomana, 2005, Journal of dental research.

IgA antibody as a non-inflammatory regulator of immunity.

J. Mestecky, M. Russell, E. Nikolova, 1997, Biochemical Society transactions.

Autoimmunity to collagen in adult periodontal disease.

E. J. Miller, S. Gay, J. Mestecky, 1988, Journal of oral pathology.

Mucosal antibody responses to HIV.

J. Mestecky, Z. Moldoveanu, 2009, Methods in molecular biology.

Appendix I – Collection and Processing of Human Mucosal Secretions

J. Mestecky, Z. Moldoveanu, S. Jackson, 2005 .

Paucity of antigen-specific IgA responses in sera and external secretions of HIV-type 1-infected individuals.

M. Mulligan, P. Goepfert, J. Mestecky, 2004, AIDS research and human retroviruses.

Detection of mucosal antibodies in HIV type 1-infected individuals.

P. Goepfert, H. Staats, P. Wright, 2002, AIDS research and human retroviruses.

Interactions of galactosyltransferase with serum and secretory immunoglobulins and their component chains.

J. Mestecky, J. Zikán, J. Bennett, 1993, Molecular immunology.

Properties of IgA-binding receptors on murine T cells: relative importance of Fc alpha R, beta-galactosyltransferase and anti-secretory component reactive proteins (ASCP).

M. McGhee, J. Mcghee, H. Kiyono, 1992, Scandinavian journal of immunology.

Cloning of the chicken immunoglobulin joining (J)-chain gene and characterization of its promoter region.

K. Komiyama, J. Mestecky, I. Moro, 2002, DNA and cell biology.

Immunology of Milk and the Neonate

J. Mestecky, P. Ogra, C. Blair, 2012, Advances in Experimental Medicine and Biology.

Oral Tolerance in Humans: Failure to Suppress an Existing Immune Response by Oral Antigen Administration

C. Elson, J. Mestecky, Z. Moldoveanu, 2004, Annals of the New York Academy of Sciences.

Secretory Immunity in the Female Reproductive Tract

J. Mestecky, W. Kutteh, 1994, American journal of reproductive immunology.

Secretory IgA oligosaccharide chains as receptors for bacterial lectins

J. Mestecky, C. Svanborg-Edén, A. Wold, 1990 .

T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8‐positive cells are recruited to invasion

R. P. Edwards, E. Partridge, J. Mestecky, 1995, Cancer.

Immunoglobulin A subclass distribution of naturally occurring salivary antibodies to microbial antigens

J. Mestecky, T. A. Brown, 1985, Infection and immunity.

Molecular weight of a human J chain.

J. Mestecky, R. Schrohenloher, T. Stanton, 1973, Biochimica et biophysica acta.

Distribution of IgA1-, IgA2-, and J chain-containing cells in human tissues.

J. Mestecky, I. Moro, S. Crago, 1984, Journal of immunology.

The interactions of human complement with interfacially aggregated preparations of human secretory IgA.

J. Mestecky, K. Pruitt, R. Boackle, 1974, Immunochemistry.

Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

J. Kappes, G. Shaw, J. Orenstein, 2002, Nature Medicine.

Immunoglobulin A (IgA): molecular and cellular interactions involved in IgA biosynthesis and immune response.

J. Mcghee, J. Mestecky, 1987, Advances in immunology.

Chemokine Adjuvanted Electroporated-DNA Vaccine Induces Substantial Protection from Simian Immunodeficiency Virus Vaginal Challenge

N. Sardesai, D. Weiner, M. Kutzler, 2015, Mucosal Immunology.

Binding of serum immunoglobulins to collagens in IgA nephropathy and HIV infection.

B. Julian, R. Gay, S. Gay, 1992, Kidney international.

Subclass distribution and molecular form of immunoglobulin A hemagglutinin antibodies in sera and nasal secretions after experimental secondary infection with influenza A virus in humans

B. Murphy, J. Mestecky, T. A. Brown, 1985, Journal of clinical microbiology.

Tissue origins of human polymeric and monomeric IgA.

J. Mestecky, S. Prince, W. Kutteh, 1982, Journal of immunology.

Influenza virus infection of the murine uterus: a new model for antiviral immunity in the female reproductive tract.

J. Mestecky, A. Menge, K. B. Renegar, 2006, Viral immunology.

Immune response of the female rat genital tract after oral and local immunization with keyhole limpet hemocyanin conjugated to the cholera toxin B subunit

S. Michalek, J. Mestecky, M. Russell, 1993, Infection and immunity.

Mucosal immunity and tolerance: relevance to vaccine development

M. Kieny, J. Mcghee, C. Czerkinsky, 1999, Immunological reviews.

The common mucosal immune system and current strategies for induction of immune responses in external secretions

J. Mestecky, 1987, Journal of Clinical Immunology.

Concept of the local and common mucosal immune response.

J. Mcghee, S. Michalek, J. Mestecky, 1978, Advances in experimental medicine and biology.

Effective immunity to dental caries: selective induction of secretory immunity by oral administration of Streptococcus mutans in rodents.

J. Mcghee, S. Michalek, J. Mestecky, 1978, Advances in experimental medicine and biology.

Ingestion of Streptococcus mutans induces secretory immunoglobulin A and caries immunity

J. Mestecky, R. Arnold, L. Bozzo, 1976, Science.

Immune responses to human papillomavirus in genital tract of women with cervical cancer.

L. Chow, R. Alvarez, G. Jin, 2005, Gynecologic oncology.

Secretory Immunity and Infection

J. Mcghee, J. Mestecky, J. Babb, 1978, Advances in Experimental Medicine and Biology.

Serum IgG and IgM levels to bacterial antigens in necrotizing ulcerative gingivitis.

J. Mestecky, J. Gunsolley, R. Cogen, 1993, Journal of periodontology.

HIV infection: first battle decides the war.

J. Mcghee, Z. Hel, J. Mestecky, 2006, Trends in immunology.

The Secretory immune system

J. Mcghee, J. Mestecky, 1983 .

The carbohydrate composition of glycopeptides isolated from IgA2 immunoglobulin.

J. Mestecky, W. Niedermeier, M. Tomana, 1974, Advances in Experimental Medicine and Biology.

Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure.

J. Skurnick, S. Vermund, D. Nixon, 2002, The Journal of infectious diseases.

7 – Mucosal Immunoglobulins

J. Mestecky, B. Underdown, 1994 .

Bacteroides-specific IgG and IgA subclass antibody-secreting cells isolated from chronically inflamed gingival tissues.

T. Ogawa, J. Mcghee, S. Hamada, 1989, Clinical and experimental immunology.

Distribution of immunoglobulin isotypes including IgA subclasses in adult, juvenile, and rapidly progressive periodontitis.

M. Kilian, J. Mestecky, B. Ellegaard, 1989, Journal of clinical periodontology.

Analysis of human IgG and IgA subclass antibody-secreting cells from localized chronic inflammatory tissue.

T. Ogawa, J. Mcghee, S. Hamada, 1989, Journal of immunology.

Studies on human secretory immunoglobulin A. IV. Carbohydrate composition.

J. Mestecky, W. Niedermeier, M. Tomana, 1972, Journal of immunology.

Phylogeny of the immunogloblin joining (J) chain.

J. Mestecky, I. Moro, T. Iwase, 1995, Advances in experimental medicine and biology.

Parallel synthesis of immunoglobulins and J chain in pokeweed mitogen- stimulated normal cells and in lymphoblastoid cell lines

R. Winchester, H. Kunkel, J. Mestecky, 1977, The Journal of experimental medicine.

Glycosylation of IgA1 and pathogenesis of IgA nephropathy

B. Julian, J. Novak, J. Mestecky, 2012, Seminars in Immunopathology.

Determination of Aberrant O-Glycosylation in the IgA1 Hinge Region by Electron Capture Dissociation Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry*

H. Cooper, J. Novak, M. Emmett, 2005, Journal of Biological Chemistry.

Protective Activities of Mucosal Antibodies

J. Mestecky, 2020 .

Specific antibody activity, glycan heterogeneity and polyreactivity contribute to the protective activity of S-IgA at mucosal surfaces

J. Mestecky, M. Russell, 2009, Immunology Letters.

Isolation and Separation of Human Colostral and Milk Cells

J. Mestecky, S. Crago, 1987 .

Cellular Signaling and Production of Galactose-Deficient IgA1 in IgA Nephropathy, an Autoimmune Disease

B. Julian, J. Novak, C. Willey, 2014, Journal of immunology research.

Secretory IgA1 and IgA2 Responses to Environmental Antigens

J. Mestecky, M. Russell, J. Radl, 1985 .

Serum and Salivary IgA1, IgA2, IgG and IgM Antibodies to Bacterial Antigens in Aged, Edentulous, and Normal Adults

J. Mestecky, M. Russell, G. Ligthart, 1989 .

Assay of human IgA subclass antibodies in serum and secretions by means of monoclonal antibodies.

J. Mestecky, M. Russell, T. A. Brown, 1986, Journal of immunological methods.

The origin of monomeric and polymeric forms of IgA in man.

J. Mestecky, J. Radl, W. Hijmans, 1974, Advances in experimental medicine and biology.

Naturally occurring secretory immunoglobulin A antibodies to Streptococcus mutans in human colostrum and saliva

J. Mcghee, J. Mestecky, R. Arnold, 1976, Infection and immunity.

Secretory immunity and immunodeficiency.

J. Mcghee, J. Mestecky, D. Lynch, 1978, Advances in experimental medicine and biology.

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

J. Novak, M. Hoelscher, L. Maboko, 2014, AIDS Research and Therapy.

Natural killer cells in human colostrum.

K. Komiyama, J. Mestecky, I. Moro, 1985, Cellular immunology.

Human colostral cells. II. Response to mitogens.

J. Mestecky, S. Crago, 1984, Cellular immunology.

Hemolytic plaque formation by cellular and noncellular elements of human colostrum.

J. Mestecky, S. Crago, W. Kutteh, 1981, Journal of immunology.

Molecular-cellular interactions in the secretory IgA response.

J. Mcghee, H. Kiyono, S. Michalek, 1980, Journal of the Reticuloendothelial Society.

Association of S-IgA subunits.

J. Mestecky, R. Schrohenloher, M. Tomana, 1974, Advances in experimental medicine and biology.

Mucosal Immunity in COVID-19: A Neglected but Critical Aspect of SARS-CoV-2 Infection

J. Mestecky, M. Russell, Z. Moldoveanu, 2020, Frontiers in Immunology.

Molecular forms of tear IgA and distribution of IgA subclasses in human lacrimal glands.

J. Mestecky, J. Radl, J. Haaijman, 1985, The Journal of allergy and clinical immunology.

Human Male Genital Tract Secretions: Both Mucosal and Systemic Immune Compartments Contribute to the Humoral Immunity1

J. Mestecky, Z. Moldoveanu, M. Pate, 2005, The Journal of Immunology.

Mucosal and Systemic Immune Human Male Genital Tract Secretions: Both

J. Mestecky, Z. Moldoveanu, M. Pate, 2005 .

Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads.

J. Bremer, P. Reichelderfer, J. Mestecky, 2004, The Journal of infectious diseases.

A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjects.

J. Lambert, M. Mulligan, W. Koff, 2001, Vaccine.

Human immune responses to influenza virus vaccines administered by systemic or mucosal routes.

B. Murphy, M. Clements, J. Mestecky, 1995, Vaccine.

Immune response versus mucosal tolerance to mucosally administered antigens.

C. Elson, J. Mestecky, Z. Moldoveanu, 2005, Vaccine.

IgA Nephropathy and Related Diseases

B. Julian, J. Novak, M. Raška, 2015 .

Expression Of SC, IL-6 and TGF-β1 in Epithelial Cell Lines

P. Krajči, J. Mestecky, I. Moro, 1995 .

J. chain disease: a novel form of plasma cell dyscrasia.

B. Julian, J. Prchal, J. Mestecky, 1990, The American journal of medicine.

Immunoglobulin A (IgA) polymerization sites in human immunocytes: immunoelectron microscopic study.

K. Komiyama, J. Mestecky, I. Moro, 1990, Cell structure and function.

FUNCTION AND BIOSYNTHESIS OF POLYMERIC IgA *

J. Mestecky, M. Russell, I. Moro, 1983, Annals of the New York Academy of Sciences.

Studies on human secretory immunoglobulin A. 3. J chain.

J. Mestecky, W. Butler, J. Zikán, 1972, Immunochemistry.

Properties of immunoglobulin A in serum of individuals with liver diseases and in hepatic bile

J. Mestecky, S. Prince, W. Kutteh, 1982 .

Humoral immune responses to the human immunodeficiency virus type-1 (HIV-1) in the genital tract compared to other mucosal sites.

J. Mestecky, 2006, Journal of reproductive immunology.

Saliva as a Manifestation of the Common Mucosal Immune System a

J. Mestecky, 1993, Annals of the New York Academy of Sciences.

A method for quantification of absolute amounts of nucleic acids by (RT)-PCR and a new mathematical model for data analysis.

J. Mestecky, M. Russell, H L Vu, 2000, Nucleic acids research.

Mucosal HIV vaccines: a holy grail or a dud?

J. Mestecky, F. Diaz-Mitoma, A. Azizi, 2010, Vaccine.

Recombinant human interleukin 6 (rhIL-6) promotes the terminal differentiation of in vivo-activated human B cells into antibody-secreting cells.

T. Hirano, J. Mcghee, H. Kiyono, 1991, Cellular immunology.

Regulation of human IgA and IgA subclass synthesis by recombinant interleukin-6

T. Hirano, J. Mcghee, H. Kiyono, 1990 .

Human appendix B cells naturally express receptors for and respond to interleukin 6 with selective IgA1 and IgA2 synthesis.

T. Hirano, J. Mcghee, H. Kiyono, 1991, The Journal of clinical investigation.

IgA Nephropathy: Pleiotropic impact of Epstein-Barr virus infection on immunopathogenesis and racial incidence of the disease

B. Julian, M. Raška, J. Mestecky, 2023, Frontiers in Immunology.

Method of serum IgA isolation.

J. Mestecky, F. W. Kraus, R. Kulhavy, 1971, Journal of immunology.

Identification and properties of J chain isolated from catfish macroglobulin.

J. Mestecky, R. Schrohenloher, M. Tomana, 1975, Journal of immunology.

Studies on human secretory immunoglobulin A. VI. Cyanogen bromide cleavage.

J. Mestecky, M. Tomana, R. Kulhavy, 1974, Journal of immunology.

Site of attachment of J chain to human immunoglobulin M

J. Mestecky, R. Schrohenloher, RALPH E. SCHROHENLOHER, 1974, Nature.

Site of J chain attachment to human polymeric IgA.

J. Mestecky, R. Schrohenloher, M. Tomana, 1974, Proceedings of the National Academy of Sciences of the United States of America.

The J chain of polymeric immunoglobulins.

J. Mestecky, F. Inman, F. P. Inman, 1974, Contemporary topics in molecular immunology.

The carbohydrate composition of J chain from human serum and secretory IgA.

J. Mestecky, W. Niedermeier, M. Tomana, 1972, Biochimica et biophysica acta.

Species distribution of J chain.

J. Mestecky, R. Acton, P. Weinheimer, 1971, Journal of immunology.

The Immunoglobulin a System

J. Mestecky, A. Lawton, 1974 .

Proportion of human colostral immunoglobulin-A molecules containing the secretory determinant.

J. Mestecky, F. W. Kraus, S. Voight, 1970, Immunology.

A simple quantitative method for α-amylase determinations

D. C. Hurst, J. Mestecky, F. W. Kraus, 1969 .

Induction of secretory antibodies in humans following ingestion of Streptococcus mutans.

J. Mcghee, S. Michalek, J. Mestecky, 1978, Advances in experimental medicine and biology.

Intraperitoneal administration of tetanus toxoid elicits a specific response of antibody-secreting cells in the peritoneal cavity.

B. Julian, C. Elson, J. Mestecky, 1995, Advances in experimental medicine and biology.

Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody‐secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA response

B. Julian, C. Elson, J. Mestecky, 1994, Clinical and experimental immunology.

Immunological properties and differentiation potential of human colostral lymphocytes of B cell lineage.

J. Mcghee, J. Mestecky, I. Moro, 1991, Advances in experimental medicine and biology.

Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy

B. Julian, P. Hubáček, M. Raška, 2020, Frontiers in Immunology.

Heterosubtypic Immunity to Influenza A Virus Infection Requires a Properly Diversified Antibody Repertoire

R. Schelonka, I. Ivanov, J. Mestecky, 2007, Journal of Virology.

Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection.

Z. Hel, J. Mestecky, E. Stringer, 2010, Endocrine reviews.

Tolerance and Protection against Infection in the Genital Tract

J. Mestecky, M. Russell, 2010, Immunological investigations.

The common mucosal immune system in the human genital tract and mammary gland

J. Mestecky, W. Kutteh, J. H. Peterman, 1989 .

Oral immunization: an update

H. Kiyono, C. Czerkinsky, J. Mestecky, 2008, Current opinion in gastroenterology.

IgA-mediated elimination of antigens by the hepatobiliary route.

J. Mestecky, M. Russell, T. A. Brown, 1983, Federation proceedings.

Hepatobiliary transport of IgA immune complexes: molecular and cellular aspects.

J. Mestecky, M. Russell, T. A. Brown, 1982, Journal of immunology.

Nomenclature of immunoglobulin A and other proteins of the mucosal immune system

J. Mestecky, I. Moro, P. Brandtzaeg, 1999, Journal of immunological methods.

Liposomes containing anti-idiotypic antibodies: an oral vaccine to induce protective secretory immune responses specific for pathogens of mucosal surfaces

S. Michalek, J. Mestecky, N. Childers, 1990, Infection and immunity.

New Strategies for Oral Immunization

J. Mcghee, J. Mestecky, 1989, Current Topics in Microbiology and Immunology.

Preferential transport of IgA and IgA-immune complexes to bile compared with other external secretions.

J. Mestecky, M. Russell, T. A. Brown, 1982, Molecular immunology.

The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy

B. Julian, J. Novak, M. Raška, 2016, Front. Immunol..

CiRCULATiNG igA-CONTAiNiNG iMMUNe COMPLeXeS iN igA NePHROPATHY AND HeNOCH – SCHÖNLeiN PURPURA NePHRiTiS

B. Julian, J. Novak, M. Raška, 2016 .

Decreased IgA-producing cells in the gut of SIV-infected rhesus monkeys.

J. Mcghee, P. Marx, J. Eldridge, 1995, Advances in experimental medicine and biology.

Progress in Molecular and Genetic Studies of IgA Nephropathy

B. Julian, J. Novak, J. Mestecky, 2001, Journal of Clinical Immunology.

Systemic and Mucosal Differences in HIV Burden, Immune, and Therapeutic Responses

Mardge H. Cohen, S. Wahl, W. Mack, 2011, Journal of acquired immune deficiency syndromes.

Surface expression of secretory component and HLA class II DR antigen on glandular epithelial cells from human endometrium and two endometrial adenocarcinoma cell lines

J. Mestecky, A. Menge, 1993, Journal of Clinical Immunology.

Basic and clinical aspects of IgG subclasses: subclasses in other immunoglobulins

J. Mestecky, M. Russell, I. Mota, 1986 .

Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins.

Feng Gao, Zhiping Weng, Z. Weng, 2007, Virology.

Agglutination of E. coli by secretory IgA--a result of interaction between bacterial mannose-specific adhesins and immunoglobulin carbohydrate?

J. Mestecky, A. Wold, C. Svanborg Edén, 1988, Monographs in allergy.

Immunoglobulin isotype distribution of locally produced autoantibodies to collagen type I in adult periodontitis. Relationship to periodontal treatment.

R. Jonsson, S. Gay, J. Mestecky, 1991, Journal of clinical periodontology.

False positivity of enzyme-linked immunosorbent assay for measurement of secretory IgA antibodies directed at HIV type 1 antigens.

J. Mestecky, S. Prince, S. Jackson, 2000, AIDS research and human retroviruses.

Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection.

Z. Hel, J. Mestecky, Z. Moldoveanu, 2009, Journal of reproductive immunology.

Interaction of Mucosal Microbiota with the Innate Immune System

J. Mestecky, T. Hudcovic, H. Kozakova, 2005, Scandinavian journal of immunology.

DISTRIBUTION OF IgA1 AND IgA2 SUBCLASSES IN HUMAN TISSUE: CORRELATION WITH THE PRESENCE OF J‐CHAIN *

J. Mestecky, S. Crago, J. Radl, 1983 .

Structure of antibodies.

J. Mestecky, Jiri Mestecky, 1972, Journal of oral pathology.

Cloning and expression of the turtle (Trachemys scripta) immunoglobulin joining (J)-chain cDNA

J. Mestecky, I. Moro, Kunihiko Kobayashi, 2002, Immunogenetics.

Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group.

R. Siliciano, E. Paoletti, J. Mascola, 1998, The Journal of infectious diseases.

Compartmentalization within the common mucosal immune system.

R. Compans, J. Mestecky, M. Russell, 1995, Advances in experimental medicine and biology.

Induction of immune responses to SIV antigens by mucosally administered vaccines.

R. Compans, J. Mestecky, Z. Moldoveanu, 1999, AIDS research and human retroviruses.

Perspectives on Mucosal Vaccines: Is Mucosal Tolerance a Barrier?1

C. Elson, J. Mestecky, M. Russell, 2007, The Journal of Immunology.

Enhancing Oral Vaccine Potency by Targeting Intestinal M Cells

J. Mestecky, F. Diaz-Mitoma, A. Azizi, 2010, PLoS pathogens.

Two Cells, One Antibody: The Discovery of the Cellular Origins and Transport of Secretory IgA

J. Mestecky, F. Johansen, C. Kaetzel, 2017, The Journal of Immunology.

Ontogeny of J chain expression in pig lymphocytes.

J. Mestecky, J. Zikán, L. Mandel, 1985, Immunology letters.

Heterogeneity of Aberrant O-Glycosylation of IgA1 in IgA Nephropathy

B. Julian, J. Novak, Hitoshi Suzuki, 2016 .

Chapter 4 Heterogeneity of Aberrant O-Glycosylation of IgA 1 in IgA Nephropathy

B. Julian, J. Novak, Hitoshi Suzuki, 2016 .

Oral immunization with bacterial antigen induces IgA-secreting cells in peripheral blood in humans.

J. Mcghee, S. Michalek, C. Czerkinsky, 1987, Advances in experimental medicine and biology.

NON-SPECIFIC MESANGIAL STAINING WITH ANTIBODIES AGAINST CYTOMEGALOVIRUS IN IMMUNOGLOBULIN-A NEPHROPATHY

W. Britt, B. Julian, J. Mestecky, 1989, The Lancet.

The Nature of the Polymeric Serum IgA In Man 1

A. Swart, J. Mestecky, J. Radl, 1975, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Galactose-Deficient IgA1 B cells in the Circulation of IgA Nephropathy Patients Carry Preferentially Lambda Light Chains and Mucosal Homing Receptors

M. Raška, J. Mestecky, Kazuo Takahashi, 2022, Journal of the American Society of Nephrology : JASN.

Heterogeneity of O-glycosylation in the hinge region of human IgA1.

J. Novak, M. Kilian, J. Mestecky, 2000, Molecular immunology.

IgA nephropathy: molecular mechanisms of the disease.

B. Julian, J. Novak, A. Gharavi, 2013, Annual review of pathology.

Glycosylation of IgA1 and pathogenesis of IgA nephropathy

B. Julian, J. Novak, J. Mestecky, 2012, Seminars in Immunopathology.

Naturally occurring structural isomers in serum IgA1 o-glycosylation.

B. Julian, J. Novak, M. Kilian, 2012, Journal of proteome research.

IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.

B. Julian, J. Novak, Hitoshi Suzuki, 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Rectal Immunization for Induction of Specific Antibody in the Genital Tract of Women

E. Partridge, J. Mestecky, R. Edwards, 1997, Journal of Clinical Immunology.

Heterosubtypic immunity to influenza A virus infection requires B cells but not CD8+ cytotoxic T lymphocytes.

J. Mcghee, J. Mestecky, H. L. Vu, 2001, The Journal of infectious diseases.

Tolerance a Barrier? Perspectives on Mucosal Vaccines: Is Mucosal

C. Elson, J. Mestecky, M. Russell, 2011 .

Mucosal Tolerance a Barrier? Perspectives on Mucosal Vaccines: Is

C. Elson, J. Mestecky, M. Russell, 2007 .

Routes of immunization and antigen delivery systems for optimal mucosal immune responses in humans.

S. Michalek, J. Mestecky, M. Russell, 1997, Behring Institute Mitteilungen.

Passive and active protection against disorders of the gut.

J. Mestecky, M. Russell, 1998, The Veterinary quarterly.

Vitamin A is required for regulation of polymeric immunoglobulin receptor (pIgR) expression by interleukin-4 and interferon-gamma in a human intestinal epithelial cell line.

J. Mestecky, C. Stephensen, Z. Moldoveanu, 1998, The Journal of nutrition.

Immunohistochemical study of the ontogeny of the secretory immune system.

J. Mestecky, I. Moro, T. Iwase, 1987, Advances in experimental medicine and biology.

Biochemical and Molecular Roles of Nutrients Vitamin A Is Required for Regulation of Polymeric Immunoglobulin Receptor (pIgR) Expression by Interleukin-4 and Interferon-g in a Human Intestinal Epithelial Cell Line

J. Mestecky, C. Stephensen, Z. Moldoveanu, 1998 .

Human milk peroxidase is derived from milk leukocytes.

J. Mestecky, Z. Moldoveanu, K. Pruitt, 1982, Biochimica et biophysica acta.

Immune Mechanisms in Periodontitis: Total and Antigen-Specific IgG and IgA Subclass Antibody-Producing Cells at the Disease Site

J. Mcghee, H. Kiyono, J. Mestecky, 1989 .

Evaluation of Mucosal Humoral and Cellular Immune Responses to HIV in External Secretions and Mucosal Tissues.

J. Mestecky, S. Sabbaj, 2019, Current immunology reviews.

Humoral Immune Responses to HIV in the Mucosal Secretions and Sera of HIV‐Infected Women

J. Novak, M. Raška, J. Mestecky, 2014, American journal of reproductive immunology.

Methods for Evaluation of Humoral Immune Responses in Human Genital Tract Secretions

J. Mestecky, Z. Moldoveanu, Q. Wei, 2011, American journal of reproductive immunology.

Antibody-mediated protection and the mucosal immune system of the genital tract: relevance to vaccine design.

J. Novak, M. Raška, J. Mestecky, 2010, Journal of reproductive immunology.

Neutralizing antibodies in mucosal secretions: IgG or IgA?

J. Mestecky, Rashada C. Alexander, 2007, Current HIV research.

Humoral immune responses to the human immunodeficiency virus type-1 (HIV-1) in the genital tract compared to other mucosal sites.

J. Mestecky, 2006, Journal of Reproductive Immunology.

Effects of Endogenous Gut LPS on Cells of the Secretory Immune System

J. Mcghee, S. Michalek, J. Mestecky, 1986 .

Delivery of DNA HIV-1 vaccine to the liver induces high and long-lasting humoral immune responses.

J. Novak, R. Compans, Chinglai Yang, 2008, Vaccine.

European Union and EDCTP strategy in the global context: recommendations for preventive HIV/AIDS vaccines research.

Q. Sattentau, J. H. van de Wijgert, T. Lehner, 2005, Vaccine.

Recent Advances in Mucosal Immunology

J. Mcghee, J. Bienenstock, J. Mestecky, 1987, Advances in Experimental Medicine and Biology.

HIV-1/simian immunodeficiency virus infection of human and nonhuman primate lymphocytes results in the migration of CD2+ T cells into the intestine of engrafted SCID mice.

P. Fultz, A. Kantele, J. Cummins, 1998, Journal of immunology.

Intestine of Engrafted SCID Mice T Cells into the + Results in the Migration of CD2 of Human and Nonhuman Primate Lymphocytes HIV-1/Simian Immunodeficiency Virus Infection

P. Fultz, A. Kantele, J. Cummins, 1998 .

Mechanism of heterosubtypic immunity to influenza A virus infection

J. Mcghee, J. Mestecky, H. Nguyen, 2001 .

In vitro exposure to highly cytopathic HIV-1 X4 strains increases expression of mucosa-associated integrins on CD4(+) T cells.

J. Cummins, J. Mestecky, S. Hall, 2001, Virology.

IgA nephropathy: characterization of IgG antibodies specific for galactose-deficient IgA1.

Yasuhiko Tomino, Stacy Hall, B. Julian, 2007, Contributions to nephrology.

Heterosubtypic immunity to lethal influenza A virus infection is associated with virus-specific CD8(+) cytotoxic T lymphocyte responses induced in mucosa-associated tissues.

J. Mcghee, H. Kiyono, J. Mestecky, 1999, Virology.

Immunoblastic lymphoma: An immunologic study

J. Prchal, J. Mestecky, S. Crago, 1981, Cancer.

Immunoinhibitory elements in human colostrum

J. Mestecky, S. Crago, 1983, Survey of immunologic research.

Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy

R. Greenblatt, M. Cho, B. Herold, 2017, PloS one.

The stoichiometry of J chain in human secretory dimeric IgA.

J. Mestecky, J. Zikán, J. Bennett, 1986, Molecular immunology.

Analysis of paraprotein transport into the saliva by using anti-idiotype antibodies.

M. Cooper, J. Mestecky, W. Koopman, 1987, Journal of immunology.

Studies on human dental plaque. 2. Immunochemical characteristics.

J. Mestecky, R. Holt, 1975, Journal of oral pathology.

Presence of J chain in human lymphoid cells.

J. Prchal, J. Mestecky, S. Crago, 1980, Clinical and experimental immunology.

Anti-adhesive molecules in human milk.

C. Svanborg, J. Mestecky, G. Aniansson, 1991, Advances in experimental medicine and biology.

Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins.

B. Julian, J. Novak, M. Kilian, 2007, Molecular immunology.

Site of Catabolism of Autologous and Heterologous IgA in Non‐Human Primates

K. Komiyama, J. Mestecky, I. Moro, 1990, Scandinavian journal of immunology.

HNK-1+ (Leu-7) cells and natural killer cell activity in inflamed human gingival tissue.

K. Komiyama, J. Mestecky, I. Moro, 1988, Journal of oral pathology.

Presence of antibodies specific to cartilage-type collagen in rheumatoid synovial tissue.

E. J. Miller, J. Mestecky, 1975, Clinical and experimental immunology.

IgA subclasses of human colostral antibodies specific for microbial and food antigens.

J. Mestecky, J. H. Peterman, I. Ladjeva, 1989, Clinical and experimental immunology.

Mucosal immunity and strategies for novel microbial vaccines

R. Compans, J. Mestecky, Z. Moldoveanu, 1994, Acta paediatrica Japonica : Overseas edition.

Homeostasis of the Mucosal Immune System

J. Mestecky, Jiri Mestecky, 2001 .

Immune responses to influenza virus in orally and systemically immunized mice.

R. Ray, R. Compans, J. Eldridge, 1989, Current topics in microbiology and immunology.

Regulation of mucosal responses by CD4+ T lymphocytes: effects of anti-L3T4 treatment on the gastrointestinal immune system.

J. Mcghee, J. Eldridge, J. Mestecky, 1991, International immunology.

Novel oral vaccines: the effectiveness of cloned gene products on inducing secretory immune responses.

S. Michalek, R. Curtiss, J. Mestecky, 1987, Advances in experimental medicine and biology.

Introduction to the Structural and Cellular Aspects of the Secretory IgA System

J. Mestecky, J. Mestecky, 1976, Journal of dental research.

Cellular analysis of functional mononuclear cells from chronically inflamed gingival tissue.

T. Ogawa, J. Mcghee, H. Kiyono, 1989, Regional immunology.

Role for antibodies in heterosubtypic immunity: the link between innate and adaptive immunity

J. Mcghee, A. Szalai, J. Mestecky, 2004 .

[IgA Nephropathy. Facts, uncertainties, and potential causal therapy approaches].

M. Raška, J. Mestecky, J. Dušek, 2015, Casopis lekaru ceskych.

Oral immunization studies with Streptococcus mutans and influenza vaccines in rhesus macaque monkeys.

A. Lackner, R. Lallone, S. Michalek, 1995, Advances in Experimental Medicine and Biology.

Role of nuclear factor-kappaB in the expression by tumor necrosis factor-alpha of the human polymeric immunoglobulin receptor (plgR) gene.

J. Mestecky, I. Moro, Z. Moldoveanu, 2000, Immunogenetics.

Chemokine Adjuvanted Electroporated-DNA Vaccine Induces Substantial Protection from Simian Immunodeficiency Virus Vaginal Challenge

N. Sardesai, D. Weiner, M. Kutzler, 2015, Mucosal Immunology.

The joining (J) chain is present in invertebrates that do not express immunoglobulins.

J. Mestecky, I. Moro, Z. Moldoveanu, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Immunoglobulin J Chain An Early Differentiation Marker of Human B Cells

M. Cooper, J. Mestecky, I. Moro, 1997, Annals of the New York Academy of Sciences.

Joining (J) Chain

J. Mestecky, 1998 .

Mucosal immunity in the human female reproductive tract: cytotoxic T lymphocyte function in the cervix and vagina of premenopausal and postmenopausal women.

A. Givan, J. Mestecky, H. White, 1997, American journal of reproductive immunology.

The use of the hu-PBL-SCID mouse model to study lymphocyte homing and responsiveness to recall antigens.

J. Mcghee, H. Kiyono, J. Mestecky, 1992, Regional immunology.

Secretory IgA Monoclonal Monomeric IgA , Polymeric IgA , and In Vitro Comparison of the Biologic Activities of

G. Jackson, J. Mestecky, K. B. Renegar, 1998 .

Oral Streptococcus mutans vaccines: diversity of approaches for the induction of mucosal responses

S. Michalek, J. Mestecky, N. Childers, 1990 .

Induction of human secretory and serum immune responses: molecular properties of IgA antibodies

J. Mcghee, H. Kiyono, C. Czerkinsky, 1990 .

Oral-parenteral immunization leads to the appearance of IgG auto-anti-idiotypic cells in mucosal tissues.

J. Mestecky, S. Jackson, 1981, Cellular immunology.

Secretory component: interactions with intracellular and surface immunoglobulins of human lymphoid cells.

J. Mestecky, S. Crago, 1979, Journal of immunology.

Monoclonal IgG3-kappa and IgG1-lambda proteins with different idiotypic determinants present in a single patient.

J. Mestecky, S. Sarasombath, F. Skvaril, 1977, Clinical and experimental immunology.

Molecular form and subclass distribution of IgA antibodies after immunization with live and inactivated influenza A vaccines.

B. Murphy, M. Clements, J. Mestecky, 1987, Advances in experimental medicine and biology.

Presence of plasma cells binding autologous antibody during an immune response

J. Mestecky, S. Jackson, 1979, The Journal of experimental medicine.

Hydrostatic Pressure Induces the Fusion-active State of Enveloped Viruses*

D. Foguel, Jerson L. Silva, A. A. Ano Bom, 2002, The Journal of Biological Chemistry.

Peyer’s Patches as the Inductive Site for IgA Responses

C. Elson, J. Mestecky, 2008, The Journal of Immunology.

An IgA-binding Peptide Derived from a Streptococcal Surface Protein*

E. Johnsson, G. Lindahl, J. Mestecky, 1999, The Journal of Biological Chemistry.

Overview: The Mucosal Immune System

B. Lambrecht, J. Mestecky, M. Russell, 2015 .

IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.

G. Alarcón, B. Julian, J. Novak, 2008, The Journal of clinical investigation.

Interleukin Cascade for the Regulation of IgA Synthesis and Immune Responses

J. Mcghee, H. Kiyono, J. Eldridge, 1989 .

Induction of Oral Tolerance

C. Elson, S. Husby, J. Mestecky, 2006 .

IgA nephropathy, the most common glomerulonephritis worldwide. A neglected disease in the United States?

B. Julian, J. Mestecky, B A Julian, 1988, The American journal of medicine.

Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection.

Z. Hel, J. Mestecky, E. Stringer, 2010, Endocrine reviews.

The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells

D. Burton, A. Lanzavecchia, Johannes S. Gach, 2013, PLoS pathogens.

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

S. Tonegawa, J. Mcghee, H. Kiyono, 1996, The Journal of experimental medicine.

Antibodies directed at Fab of IgA in the sera of normal individuals and IgA nephropathy patients.

B. Julian, C. Czerkinsky, J. Mestecky, 1987, Advances in experimental medicine and biology.

Variances in the levels of serum lysozyme in X-irradiated mice

J. Mestecky, M. Jílek, Marie Marečková, 2008, Folia Microbiologica.

Immune Response to Clostridial Collagenase in Gingiva and other Tissues of the Rabbit

J. Mestecky, F. W. Kraus, Jiri Mestecky, 1972, Journal of dental research.

Induction and molecular properties of secretory and serum IgA antibodies specific for environmental antigens.

J. Mcghee, S. Michalek, C. Czerkinsky, 1987, Annals of allergy.