R. Metheringham

发表

An essential role for DsbA in cytochromec synthesis and formate-dependent nitrite reduction byEscherichia coli K-12

R. Metheringham, L. Griffiths, H. Crooke, 1995, Archives of Microbiology.

Effects of mutations in genes for proteins involved in disulphide bond formation in the periplasm on the activities of anaerobically induced electron transfer chains in Escherichia coli K12

D. Missiakas, S. Raina, R. Metheringham, 1996, Molecular and General Genetics MGG.

Combination vaccine based on citrullinated vimentin and enolase peptides induces potent CD4-mediated anti-tumor responses

C. Melief, C. Melief, P. Symonds, 2020, Journal for immunotherapy of cancer.

Post-translational modifications such as citrullination are excellent targets for cancer therapy.

R. Metheringham, M. Vankemmelbeke, L. Durrant, 2020, Seminars in immunology.

Novel prostate acid phosphatase‐based peptide vaccination strategy induces antigen‐specific T‐cell responses and limits tumour growth in mice

R. Rees, M. Mathieu, R. Metheringham, 2014, European journal of immunology.

Abstract A035: Citrullinated α-enolase as a novel target for cancer immunotherapy

P. Symonds, R. Metheringham, W. Xue, 2016 .

PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

P. Symonds, R. Metheringham, S. Paston, 2022, Journal for ImmunoTherapy of Cancer.

SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors

P. Symonds, R. Metheringham, H. Yagita, 2016, Oncotarget.

T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy

P. Symonds, R. Metheringham, W. Xue, 2019, Oncoimmunology.

Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

P. Symonds, R. Metheringham, W. Xue, 2022, Frontiers in Immunology.

SCIB2, an antibody DNA vaccine encoding NY-ESO-1 epitopes, induces potent antitumor immunity which is further enhanced by checkpoint blockade

P. Symonds, R. Metheringham, H. Yagita, 2016, Oncoimmunology.

DNA vaccination with T‐cell epitopes encoded within Ab molecules induces high‐avidity anti‐tumor CD8+ T cells

R. Metheringham, L. Durrant, I. Spendlove, 2010, European journal of immunology.

The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer

M. Toss, R. Metheringham, S. Paston, 2021, Pathobiology.

Targeting gp100 and TRP-2 with a DNA vaccine: Incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial

R. Plummer, H. Pandha, P. Lorigan, 2018, Oncoimmunology.

Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell-Mediated Antitumor Immunity.

P. Symonds, R. Metheringham, W. Xue, 2016, Cancer research.

A reassessment of the genetic determinants, the effect of growth conditions and the availability of an electron donor on the nitrosating activity of Escherichia coli K-12.

R. Metheringham, J. Cole, 1997, Microbiology.

Helicase antigen (HAGE)‐derived vaccines induce immunity to HAGE and ImmunoBody®‐HAGE DNA vaccine delays the growth and metastasis of HAGE‐expressing tumors in vivo

J. Pearson, R. Metheringham, A. Pockley, 2021, Immunology and cell biology.

ImmunoBody®-HAGE derived vaccine induces immunity to HAGE and delays the growth and metastasis of HAGE-expressing tumours in vivo

J. Pearson, R. Metheringham, S. McArdle, 2021 .

Citrullinated α-enolase is an effective target for anti-cancer immunity

P. Symonds, R. Metheringham, W. Xue, 2017, Oncoimmunology.

Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy

P. Symonds, R. Metheringham, A. Miles, 2021, Journal for ImmunoTherapy of Cancer.

Abstract 9035: An adjuvant clinical trial of SCIB1, a DNA vaccine that targets dendritic cells in vivo, in fully resected melanoma patients

R. Plummer, P. Lorigan, P. Patel, 2015 .

Citrullinated Epitopes Identified on Tumour MHC Class II by Peptide Elution Stimulate Both Regulatory and Th1 Responses and Require Careful Selection for Optimal Anti-Tumour Responses

P. Symonds, R. Metheringham, A. Marcu, 2021, Frontiers in Immunology.

The clinical and prognostic significance of Protein Arginine Deiminase 2 and 4 (PADI2 & PADI4) in colorectal cancer

M. Toss, R. Metheringham, S. Paston, 2020 .

Protein Arginine Deiminase 2 and 4 (PAD2 & PAD4) are independent predictors of good prognosis in colorectal cancer

R. Metheringham, S. Paston, L. Durrant, 2020, medRxiv.

A Novel HAGE/WT1-ImmunoBody® Vaccine Combination Enhances Anti-Tumour Responses When Compared to Either Vaccine Alone

R. Metheringham, A. Pockley, S. McArdle, 2021, Frontiers in Oncology.

High Avidity Cytotoxic T Lymphocytes Can Be Selected into the Memory Pool but They Are Exquisitely Sensitive to Functional Impairment

R. Metheringham, L. Durrant, Victoria A Brentville, 2012, PloS one.

Vaccines as early therapeutic interventions for cancer therapy: neutralising the immunosuppressive tumour environment and increasing T cell avidity may lead to improved responses

R. Metheringham, L. Durrant, I. Spendlove, 2010, Expert opinion on biological therapy.

Identification of an HLA‐A*0201 cytotoxic T lymphocyte epitope specific to the endothelial antigen Tie‐2

R. Rees, A. Conn, R. Metheringham, 2004, International journal of cancer.

Characterisation of Escherichia coli K-12 mutants defective in formate-dependent nitrite reduction: essential roles for hemN and the menFDBCE operon

R. Metheringham, L. Griffiths, J. Cole, 1997, Archives of Microbiology.

Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool

P. Symonds, R. Metheringham, S. Paston, 2023, Immunology.

Autophagy, citrullination and cancer

R. Metheringham, L. Durrant, Lindy G Durrant, 2016, Autophagy.

Comparison of the immune response to a self antigen after DNA immunisation of HLA*A201/H-2Kb and HHD transgenic mice.

R. Rees, R. Metheringham, L. Durrant, 2004, Vaccine.

Autophagy, citrullination and cancer

R. Metheringham, L. Durrant, Victoria A Brentville, 2016, Autophagy.