Javier Valle

发表

Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication

Xiaoping Zhou, D. Andreu, B. G. de la Torre, 2015, PloS one.

Synthetic developmental regulator MciZ targets FtsZ across Bacillus species and inhibits bacterial division

D. Andreu, Javier Valle, L. Araújo-Bazán, 2019, Molecular microbiology.

Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus.

M. V. Nogués, E. Boix, M. Nogués, 2013, The Biochemical journal.

Human Albumin Impairs Amyloid β-peptide Fibrillation Through its C-terminus: From docking Modeling to Protection Against Neurotoxicity in Alzheimer's disease

B. Oliva, Javier García-García, J. Bonet, 2019, Computational and structural biotechnology journal.

To What Extent Do Fluorophores Bias the Biological Activity of Peptides? A Practical Approach Using Membrane-Active Peptides as Models

J. Correia, V. Neves, D. Andreu, 2020, Frontiers in Bioengineering and Biotechnology.

Antimicrobial Peptides Can Generate Tolerance by Lag and Interfere with Antimicrobial Therapy

J. Morata, D. Andreu, Marc Torrent Burgas, 2022, bioRxiv.

An optimized Fmoc synthesis of human defensin 5

D. Andreu, B. G. de la Torre, Javier Valle, 2013, Amino Acids.

The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures

D. Andreu, Javier Valle, M. Prudêncio, 2022, BMC Biology.

Conjugation of a Blood Brain Barrier Peptide Shuttle to an Fc Domain for Brain Delivery of Therapeutic Biomolecules

V. Neves, D. Andreu, Javier Valle, 2021, ACS medicinal chemistry letters.

Targeting Zika Virus with New Brain- and Placenta-Crossing Peptide–Porphyrin Conjugates

V. Neves, D. Andreu, Javier Valle, 2022, Pharmaceutics.

Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope

J. L. Nieva, I. de la Arada, J. Torralba, 2022, Communications Biology.

DPepH3, an Improved Peptide Shuttle for Receptor-independent Transport across the Blood-Brain Barrier.

J. Correia, V. Neves, D. Andreu, 2020, Current pharmaceutical design.

The antimetastatic breast cancer activity of the viral protein‐derived peptide vCPP2319 as revealed by cellular biomechanics

V. Neves, D. Andreu, Javier Valle, 2021, The FEBS journal.

Development of Breast Cancer Spheroids to Evaluate Cytotoxic Response to an Anticancer Peptide

V. Neves, D. Andreu, Javier Valle, 2021, Pharmaceutics.

Rationally Modified Antimicrobial Peptides from the N-Terminal Domain of Human RNase 3 Show Exceptional Serum Stability

E. Boix, D. Andreu, Javier Valle, 2021, Journal of medicinal chemistry.

The generation of antimicrobial peptide activity: a trade-off between charge and aggregation?

Marc Torrent, David Andreu, Ester Boix, 2011, Angewandte Chemie.

Decoding the human serum interactome of snake-derived antimicrobial peptide Ctn[15-34]: Toward an explanation for unusually long half-life.

D. Andreu, Javier Valle, S. Defaus, 2019, Journal of proteomics.

An optimized Fmoc synthesis of human defensin 5

D. Andreu, B. G. de la Torre, Javier Valle, 2014, Amino Acids.

The mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms

M. Prieto, A. Coutinho, D. Andreu, 2019, The Journal of antimicrobial chemotherapy.

Towards a Sustainable Management of the Spotted-Wing Drosophila: Disclosing the Effects of Two Spider Venom Peptides on Drosophila suzukii

P. Harvey, D. Andreu, Javier Valle, 2023, Insects.

Novel antimicrobial cecropins derived from O. curvicornis and D. satanas dung beetles

Juan Felipe Osorio-Méndez, D. Andreu, Javier Valle, 2021, Peptides.

Synthesis, structure, and activity of the antifungal plant defensin PvD1.

P. Harvey, D. Andreu, S. Henriques, 2020, Journal of medicinal chemistry.

E. Boix, D. Andreu, Javier Valle, 2017, Journal of The Royal Society Interface.

siRNA‐cell‐penetrating peptides complexes as a combinatorial therapy against chronic myeloid leukemia using BV173 cell line as model

D. Andreu, F. Enguita, Javier Valle, 2017, Journal of controlled release : official journal of the Controlled Release Society.

The C-Terminus of Panusin, a Lobster β-Defensin, Is Crucial for Optimal Antimicrobial Activity and Serum Stability

D. Andreu, Javier Valle, M. Torrent, 2023, Pharmaceutics.

Estimating peptide half‐life in serum from tunable, sequence‐related physicochemical properties

D. Andreu, Javier Valle, M. Cavaco, 2021, Clinical and translational science.

Tumor Cell Attack by Crotalicidin (Ctn) and Its Fragment Ctn[15-34]: Insights into Their Dual Membranolytic and Intracellular Targeting Mechanism.

D. Andreu, Javier Valle, J. Freire, 2020, ACS chemical biology.

The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis.

Javier Valle, M. Cavaco, C. Pérez-Peinado, 2024, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

PyAMPA: a high-throughput prediction and optimization tool for antimicrobial peptides

Javier Valle, Marc Ramos-Llorens, David Andreu, 2024, mSystems.

A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers

J. Torralba, Beatriz Apellániz, Javier Valle, 2024, FEBS letters.

Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria

Javier Valle, D. Sandín, J. González-López, 2023, bioRxiv.