Hongping Dong

发表

Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA

T. Lu, S. Jaffrey, Xin-Yuan Fu, 2019, bioRxiv.

Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA

T. Lu, S. Jaffrey, Xin-Yuan Fu, 2019, Nucleic acids research.

West Nile Virus 5′-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2′-O Methylations by Nonstructural Protein 5

Yi Guo, Hongmin Li, Hongping Dong, 2006, Journal of Virology.

Functional Analysis of Two Cavities in Flavivirus NS5 Polymerase

Yen-Liang Chen, P. Shi, J. Lescar, 2011, The Journal of Biological Chemistry.

2′-O Methylation of Internal Adenosine by Flavivirus NS[subscript 5] Methyltransferase

David C. Chang, S. Lok, P. Shi, 2012 .

Flavivirus RNA methylation.

K. Fink, P. Shi, S. Lim, 2014, The Journal of general virology.

Characterization of Dengue Virus NS4A and NS4B Protein Interaction

Hongping Dong, Xuping Xie, Pei-Yong Shi, 2015, Journal of Virology.

Lead optimization of spiropyrazolopyridones: a new and potent class of dengue virus inhibitors.

Paul W Smith, P. Shi, A. Chao, 2015, ACS medicinal chemistry letters.

Rational Design of a Flavivirus Vaccine by Abolishing Viral RNA 2′-O Methylation

Xuping Xie, P. Shi, Bo Zhang, 2013, Journal of Virology.

Solvent-free coating of crosslinked and hydrophobic lignin-based biocomposite for slow-release fertilizer

Lishu Shao, P. Zhan, Jienan Chen, 2021, Polymer Testing.

Characterization of a candidate tetravalent vaccine based on 2'-O-methyltransferase mutants

E. Newell, K. Fink, Xuping Xie, 2018, PloS one.

Evasion of early innate immune response by 2′-O-methylation of dengue genomic RNA

Mark J. Schreiber, David C. Chang, M. Hibberd, 2016, Virology.

Determinants of Dengue Virus NS4A Protein Oligomerization

Xuping Xie, P. Shi, C. Kang, 2015, Journal of Virology.

Discovery of Dengue Virus NS4B Inhibitors

Paul W Smith, P. Shi, J. Lescar, 2015, Journal of Virology.

Inhibition of Dengue Virus through Suppression of Host Pyrimidine Biosynthesis

L. Kramer, P. Niyomrattanakit, K. Hoffmaster, 2011, Journal of Virology.

Characterization of Dengue Virus Resistance to Brequinar in Cell Culture

P. Shi, Qing-yin Wang, H. Xu, 2010, Antimicrobial Agents and Chemotherapy.

Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase*

P. Shi, Zhong Li, Hongmin Li, 2010, The Journal of Biological Chemistry.

Rational design of a flavivirus vaccine through abolishing 1 viral RNA 2 ′-O methylation

Xuping Xie, Bo Zhang, Hui Zhao, 2013 .

Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus.

P. Shi, J. Lescar, S. Lim, 2010, Virology.

2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase

David C. Chang, S. Lok, P. Shi, 2012, PLoS pathogens.

2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase

David C. Chang, S. Lok, P. Shi, 2012, PLoS pathogens.

Identification and characterization of inhibitors of West Nile virus.

P. Shi, Bo Zhang, Bo Zhang, 2009, Antiviral research.

Genetic analysis of West Nile virus containing a complete 3'CSI RNA deletion.

P. Shi, Bo Zhang, Hongping Dong, 2010, Virology.

Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2'-O methylations of viral RNA cap.

P. Shi, Hongmin Li, Hongping Dong, 2008, Virology.

West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism

P. Shi, Bo Zhang, Hongmin Li, 2008, Journal of Virology.

Biochemical and genetic characterization of dengue virus methyltransferase.

Hongping Dong, Xuping Xie, David C. Chang, 2010, Virology.

Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine

P. Shi, Hongping Dong, C. Noble, 2014, Antiviral Research.

Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5′ Stem-Loop of Genomic RNA

P. Shi, Bo Zhang, Hongping Dong, 2008, Journal of Virology.

Dengue NS2A Protein Orchestrates Virus Assembly.

Xinwen Chen, Xuping Xie, P. Shi, 2019, Cell host & microbe.

Strategies for development of Dengue virus inhibitors.

Yen-Liang Chen, P. Shi, W. Schul, 2010, Antiviral research.

Flavivirus RNA cap methyltransferase: structure, function, and inhibition

P. Shi, Zhong Li, Hongmin Li, 2010, Frontiers in Biology.

The role of sequence context, nucleotide pool balance and stress in 2′-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA

P. Shi, R. Cunningham, P. Dedon, 2016, Nucleic acids research.

Synergistic Suppression of Dengue Virus Replication Using a Combination of Nucleoside Analogs and Nucleoside Synthesis Inhibitors

Yen-Liang Chen, P. Shi, Qing-yin Wang, 2015, Antimicrobial Agents and Chemotherapy.

Ten years of dengue drug discovery: progress and prospects.

David Beer, Hongping Dong, Shahul Nilar, 2013, Antiviral research.

Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase*

Gang Wang, Hongping Dong, Thomas H. Keller, 2010, The Journal of Biological Chemistry.

Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel

P. Niyomrattanakit, Yen-Liang Chen, P. Shi, 2010, Journal of Virology.

NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models

G. Bonamy, V. Sasseville, Yen-Liang Chen, 2021, Science Translational Medicine.

The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.

G. Bonamy, T. Bouwmeester, R. Riedl, 2017, Cell reports.

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

Hongping Dong, Michael S. Diamond, Pei-Yong Shi, 2010, Nature.

A multidimensional platform for the purification of non-coding RNA species

P. Shi, P. Preiser, P. Dedon, 2013, Nucleic acids research.

An Allosteric PRC2 Inhibitor Targeting EED Suppresses Tumor Progression by Modulating the Immune Response

Yanni Chen, Yanchao Liu, Hongping Dong, 2019, Cancer Research.

Structure and Function of Flavivirus NS5 Methyltransferase

Yi Guo, Hongmin Li, Hongping Dong, 2007, Journal of Virology.

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions.

D. A. Stein, P. Iversen, P. Shi, 2008, Virology.

Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events

D. Ray, P. Shi, C. Ho, 2007, Journal of Virology.

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

Hongping Dong, Rishi Arora, Xuping Xie, 2016, PLoS pathogens.

Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening.

P. Niyomrattanakit, P. Shi, J. Lescar, 2015, Antiviral research.

RNA Structures Required for Production of Subgenomic Flavivirus RNA

P. Shi, A. Funk, Hongping Dong, 2010, Journal of Virology.

Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques

David C. Chang, K. Fink, M. Poidinger, 2013, PLoS pathogens.

A Translation Inhibitor That Suppresses Dengue Virus In Vitro and In Vivo

David C. Chang, L. Kramer, Xuping Xie, 2011, Antimicrobial Agents and Chemotherapy.

Flavivirus methyltransferase: a novel antiviral target.

Hongping Dong, Pei-Yong Shi, Bo Zhang, 2008, Antiviral research.

Correction: Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques

David C. Chang, K. Fink, M. Poidinger, 2013, PLoS Pathogens.

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

Chandra S Verma, Chao Shan, Hongping Dong, 2019, PLoS pathogens.

Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.

G. Bonamy, Qing-yin Wang, Hongping Dong, 2017, Bioorganic & medicinal chemistry letters.

Terminal structures of West Nile virus genomic RNA and their interactions with viral NS5 protein.

P. Shi, Bo Zhang, Hongping Dong, 2008, Virology.

Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings.

D. A. Stein, P. Shi, Bo Zhang, 2008, Virology.

Structure and Function of Flavivirus NS 5 Methyltransferase

D. Ray, Yi Guo, P. Shi, 2007 .

A systems-level mass spectrometry-based technique for accurate and sensitive quantification of the RNA cap epitranscriptome

T. Lu, S. Jaffrey, P. Shi, 2023, Nature Protocols.

EED inhibition suppresses cancers by modulating the immune response.

Yanni Chen, Yanchao Liu, Hongping Dong, 2019, Cancer research.

Dimerization of Flavivirus NS4B Protein

Ramyavardhanee Chandrasekaran, Xuping Xie, P. Shi, 2014, Journal of Virology.

Dimerization of Flavivirus NS 4 B Protein

Ramyavardhanee Chandrasekaran, Xuping Xie, J. Lescar, 2014 .