S. Mukhopadhyay

发表

Genome-wide siRNA screen identifies UNC50 as a regulator of Shiga toxin 2 trafficking

LaKesla R Iles, G. Bartholomeusz, Andrey S Selyunin, 2017, The Journal of cell biology.

Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease.

M. Aschner, Pan Chen, J. Bornhorst, 2015, Metallomics : integrated biometal science.

Monocrotaline pyrrole-induced megalocytosis of lung and breast epithelial cells: Disruption of plasma membrane and Golgi dynamics and an enhanced unfolded protein response.

P. Sehgal, S. Mukhopadhyay, M. Shah, 2006, Toxicology and applied pharmacology.

Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex

S. Pramanik, N. Sen, S. Mukhopadhyay, 2007, Cell Death and Differentiation.

Brain manganese and the balance between essential roles and neurotoxicity

M. Aschner, E. Haynes, S. Mukhopadhyay, 2020, The Journal of Biological Chemistry.

Depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.

P. Sehgal, S. Mukhopadhyay, Jason E. Lee, 2008, American journal of physiology. Heart and circulatory physiology.

Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques.

P. Sehgal, R. Tuder, S. Mukhopadhyay, 2009, American journal of physiology. Lung cellular and molecular physiology.

Dysfunctional intracellular trafficking in the pathobiology of pulmonary arterial hypertension.

P. Sehgal, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2007, American journal of respiratory cell and molecular biology.

SLC30A10 transporter in the digestive system regulates brain manganese under basal conditions while brain SLC30A10 protects against neurotoxicity

M. Aschner, S. Mukhopadhyay, W. Shawlot, 2018, The Journal of Biological Chemistry.

Glypican-1 nanoliposomes for potentiating growth factor activity in therapeutic angiogenesis.

A. Baker, A. Dunn, Brian Lam, 2016, Biomaterials.

Up-regulation of the manganese transporter SLC30A10 by hypoxia-inducible factors defines a homeostatic response to manganese toxicity

M. Aschner, S. Mukhopadhyay, Donald R. Smith, 2021, Proceedings of the National Academy of Sciences.

Translational Review Dysfunctional Intracellular Trafficking in the Pathobiology of Pulmonary Arterial Hypertension ELECTRON MICROSCOPY OF CELLULAR ELEMENTS IN

P. Sehgal, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2007 .

Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension.

P. Sehgal, S. Mukhopadhyay, M. Shah, 2007, American journal of physiology. Lung cellular and molecular physiology.

Discordant regulatory changes in monocrotaline-induced megalocytosis of lung arterial endothelial and alveolar epithelial cells.

P. Sehgal, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2006, American journal of physiology. Lung cellular and molecular physiology.

Characterization of a long-term rat mTAL cell line.

P. Sehgal, J. Mcgiff, S. Mukhopadhyay, 2007, American journal of physiology. Renal physiology.

Manganese Blocks Intracellular Trafficking of Shiga Toxin and Protects Against Shiga Toxicosis

A. Linstedt, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2012, Science.

Retrograde trafficking of AB5 toxins: mechanisms to therapeutics

A. Linstedt, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2013, Journal of Molecular Medicine.

Tamoxifen Derivatives Alter Retromer-Dependent Endosomal Tubulation and Sorting to Block Retrograde Trafficking of Shiga Toxins

Andrey S Selyunin, S. Mukhopadhyay, Stanton F. McHardy, 2021, Toxins.

A Conserved Structural Motif Mediates Retrograde Trafficking of Shiga Toxin Types 1 and 2

Andrey S Selyunin, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2015, Traffic.

Replication-induced transcription of an autorepressed gene: the replication initiator gene of plasmid P1.

D. Chattoraj, S. Mukhopadhyay, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Familial manganese-induced neurotoxicity due to mutations in SLC30A10 or SLC39A14.

S. Mukhopadhyay, 2017, Neurotoxicology.

Inherited Disorders of Manganese Metabolism.

S. Mukhopadhyay, Charles E. Zogzas, 2017, Advances in neurobiology.

Manganese homeostasis in the nervous system

M. Aschner, Pan Chen, S. Mukhopadhyay, 2015, Journal of neurochemistry.

Manganese-Induced Parkinsonism and Parkinson’s Disease: Shared and Distinguishable Features

M. Aschner, S. Mukhopadhyay, Gunnar F. Kwakye, 2015, International journal of environmental research and public health.

Aberrant cytoplasmic sequestration of eNOS in endothelial cells after monocrotaline, hypoxia, and senescence: live-cell caveolar and cytoplasmic NO imaging.

P. Sehgal, S. Mukhopadhyay, Fang Xu, 2007, American journal of physiology. Heart and circulatory physiology.

Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity.

M. Aschner, J. Bornhorst, S. Mukhopadhyay, 2020, The Journal of nutrition.

Membrane-associated STAT3 and PY-STAT3 in the Cytoplasm*

P. Sehgal, S. Mukhopadhyay, M. Shah, 2006, Journal of Biological Chemistry.

Live cell imaging of interleukin-6-induced targeting of "transcription factor" STAT3 to sequestering endosomes in the cytoplasm.

P. Sehgal, S. Mukhopadhyay, Fang Xu, 2007, American journal of physiology. Cell physiology.

Functional analyses of the UDP-galactose transporter SLC35A2 using the binding of bacterial Shiga toxins as a novel activity assay.

S. Mukhopadhyay, Danyang Li, Somshuvra Mukhopadhyay, 2019, Glycobiology.

Bacterial Cell Killing Mediated by Topoisomerase I DNA Cleavage Activity*

S. Mukhopadhyay, S. Vasunilashorn, Y. Tse‐Dinh, 2005, Journal of Biological Chemistry.

Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice

M. Aschner, A. Gore, S. Mukhopadhyay, 2017, The Journal of Biological Chemistry.

Putative metal binding site in the transmembrane domain of the manganese transporter SLC30A10 is different from that of related zinc transporters.

S. Mukhopadhyay, Charles E Zogzas, Somshuvra Mukhopadhyay, 2018, Metallomics : integrated biometal science.

Generation and Validation of Tissue‐Specific Knockout Strains for Toxicology Research

S. Mukhopadhyay, W. Shawlot, Cherish A. Taylor, 2019, Current protocols in toxicology.

Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis

Andrey S Selyunin, S. Mukhopadhyay, Stanton F. McHardy, 2019, Life Science Alliance.

Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy

Andrey S Selyunin, S. Mukhopadhyay, Danyang Li, 2020, Toxins.

Analysis of 1,25-Dihydroxyvitamin D3 Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids

P. Dhawan, G. Carmeliet, S. Mukhopadhyay, 2020, Molecular and cellular biology.

A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2

S. Mukhopadhyay, Danyang Li, Somshuvra Mukhopadhyay, 2021, The Journal of biological chemistry.

Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity

A. Linstedt, S. Mukhopadhyay, 2010, Proceedings of the National Academy of Sciences.

Manganese-induced Trafficking and Turnover of the cis-Golgi Glycoprotein GPP130

A. Linstedt, S. Mukhopadhyay, Donald R. Smith, 2010, Molecular biology of the cell.

Pulmonary arterial hypertension: a disease of tethers, SNAREs and SNAPs?

P. Sehgal, S. Mukhopadhyay, Somshuvra Mukhopadhyay, 2007, American journal of physiology. Heart and circulatory physiology.

Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control

K. Dalby, D. J. Wible, S. Mukhopadhyay, 2023, bioRxiv.

SLC30A10: A novel manganese transporter

M. Aschner, Pan Chen, S. Mukhopadhyay, 2015, Worm.

Manganese efflux transporter SLC30A10 missense polymorphism T95I associated with liver injury retains manganese efflux activity.

K. Broberg, S. Mukhopadhyay, Danyang Li, 2022, American Journal of Physiology - Gastrointestinal and Liver Physiology.

Role of excretion in manganese homeostasis and neurotoxicity: A historical perspective.

M. Aschner, S. Mukhopadhyay, Donald R. Smith, 2021, American journal of physiology. Gastrointestinal and liver physiology.

Activity of the manganese efflux transporter SLC30A10 in dopaminergic but not GABAergic neurons protects against neurotoxicity

M. Aschner, S. Mukhopadhyay, Donald R. Smith, 2022, bioRxiv.

SLC30A10 Mutation Involved in Parkinsonism Results in Manganese Accumulation within Nanovesicles of the Golgi Apparatus.

R. Ortega, P. Cloetens, J. Garrevoet, 2018, ACS chemical neuroscience.

Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by reduced thyroxine production

M. Aschner, A. Gore, R. Polishchuk, 2017, The Journal of Biological Chemistry.

Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 Are Required for Its Manganese Efflux Activity*

M. Aschner, S. Mukhopadhyay, Charles E. Zogzas, 2016, The Journal of Biological Chemistry.

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

M. Aschner, Pan Chen, S. Mukhopadhyay, 2014, The Journal of Neuroscience.

Transporter Studies: Brain Punching Technique

S. Mukhopadhyay, Cherish A. Taylor, 2019, Neuromethods.

Syndesome Therapeutics for Enhancing Diabetic Wound Healing

A. Baker, A. Dunn, M. Sherman, 2016, Advanced healthcare materials.

A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin

Huan Wang, Jiansong Xu, S. Mukhopadhyay, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Shiga toxin–binding site for host cell receptor GPP130 reveals unexpected divergence in toxin-trafficking mechanisms

A. Linstedt, S. Mukhopadhyay, Brendan Redler, 2013, Molecular biology of the cell.

Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.

P. Sehgal, R. Tuder, S. Mukhopadhyay, 2008, American journal of physiology. Lung cellular and molecular physiology.

Manganese and thyroid function in the national health and nutrition examination survey, 2011-2012.

L. Trasande, A. Ghassabian, S. Mukhopadhyay, 2023, Environmental research.

Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.

P. Sehgal, R. Tuder, S. Mukhopadhyay, 2008, American journal of physiology. Lung cellular and molecular physiology.