D. Melillo

发表

A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

Patrick R. Griffin, Arthur A. Patchett, Alex Elbrecht, 1996, Science.

Synthesis of the first sulfur-35-labeled hERG radioligand.

N. Liverton, C. Raab, D. Dean, 2006, Bioorganic & medicinal chemistry letters.

Use of Dibutyl[14C]formamide as a Formylating Reagent in the Vilsmeier–Haack Reaction and Synthesis of a 14C‐Labeled Novel Phosphodiesterase‐4 (PDE‐4) Inhibitor

D. Dean, D. Melillo, M. Braun, 2005 .

Disseminated Mycobacterium chelonei infection following cadaveric renal transplantation: favorable response to cefoxitin.

D. Melillo, J. Fish, R. Mehta, 1983, American Journal of Kidney Diseases.

Efficient utilization of [14C]carbon dioxide as a phosgene equivalent for labeled synthesis

D. Dean, D. Melillo, M. Wallace, 1997 .

A practical synthesis of (±)-thienamycin

D. Melillo, M. Sletzinger, K. M. Ryan, 1980 .

The synthesis of carbon-14 labeled pravastatin

D. Dean, D. Melillo, R. F. White, 1993 .

Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.

T. Baillie, D. Dean, D. Melillo, 2001, Drug metabolism and disposition: the biological fate of chemicals.

TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates

G. Dawson, S. Tye, R. Mckernan, 2006, Journal of Pharmacology and Experimental Therapeutics.

Synthesis of the first sulfur-35-labeled hERG radioligand.

N. Liverton, C. Raab, D. Dean, 2006, Bioorganic & medicinal chemistry letters.

Confirmation of the secondary deuterium isotope effect for the peptidyl prolyl cis-trans isomerase activity of cyclophilin by a competitive, double-label technique

D. Melillo, R. Stein, C. G. Caldwell, 1990 .

Carbon‐14 labeling of a potential new immunoregulant agent

D. Dean, D. Melillo, Z. Song, 2000 .

Cyclization of unsaturated hydroxylamine derivatives

D. Melillo, L. Lee, H. O. House, 1976 .

Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.

L. V. D. van der Ploeg, S. Pong, L. Chaung, 1996, Journal of medicinal chemistry.

Synthesis of carbon‐14 labeled LTD4 antagonist MK‐571

D. Dean, D. Melillo, R. Ellsworth, 1991 .

The synthesis of HIV reverse transcriptase inhibitors [14C]L‐697,661, [14C]L‐697,639, [14C]L‐702,007

D. Dean, D. Melillo, M. Wallace, 1996 .

Diastereoselective routes to a 1.beta.-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and -alanes

D. Melillo, I. Shinkai, D. R. Bender, 1992 .

The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs.

D. Dean, D. Melillo, G. Doss, 2000, Drug metabolism and disposition: the biological fate of chemicals.

A convenient method for [14C] carbonylation reactions

D. Dean, D. Melillo, C. Elmore, 2000 .

An Enantioselective Approach to (+)-Thienamycin from Dimethyl 1,3-Acetonedicarboxylate and (+)-α -Methylbenzylamine.

D. Melillo, R. Cvetovich, M. Sletzinger, 1986 .

An Enantioselective Approach to (+)-Thienamycin from Dimethyl 1,3-Acetonedicarboxylate and (+)-α -Methylbenzylamine.

D. Melillo, R. Cvetovich, M. Sletzinger, 1986 .

Further studies on the acetonedicarboxylate route to thienamycin—stereochemical inversion at the lactone stage.

D. Melillo, M. Sletzinger, K. M. Ryan, 1981 .

Diastereoselective Routes to a 1β-Methylcarbapenem Key Intermediate. Scope of Ate Complex Formation Between Ester Enolates and Organoboranes and -alanes.

D. Melillo, I. Shinkai, D. R. Bender, 1992 .

Practical enantioselective synthesis of a homotyrosine derivative and (R,R)-4-propyl-9-hydroxynaphthoxazine, a potent dopamine agonist

D. Melillo, D. Mathre, R. Larsen, 1987 .

Synthesis of [35S]aryl sulfonyl chlorides from [35S]elemental sulfur

C. Raab, D. Dean, D. Melillo, 2005 .

Preparation of (4-Amino-1-Hydroxybutylidene)bisphosphonic Acid Sodium Salt, MK-217 (Alendronate Sodium). An Improved Procedure for the Preparation of 1-Hydroxy-1,1-bisphosphonic Acids

D. Melillo, I. Shinkai, G. Kieczykowski, 1995 .

[14C]Dimethyltitanocene and [14C]Methyl(methyltrimethylsilyl) titanocene–Reagents for the [14C]olefination of carbonyl compounds: synthesis of [14C]Aprepitant

D. Dean, D. Melillo, M. Wallace, 2009 .

Perhydroindan derivatives. XVI. Synthesis of racemic epiallogibberic acid (3)

D. Melillo, H. O. House, 1973 .

Carbon-14 labeling of a trifluoromethoxy group : synthesis of a substance P antagonist

C. Raab, D. Dean, D. Melillo, 2001 .

Applications of LC‐ARC™ stop‐flow radiochemical detection

D. Melillo, Steven J. Staskiewicz, J. Ho, 2007 .

Chromosome anomalies in human breast cancer: evidence for specific involvement of 1q region in lymphocyte cultures.

G. Hortobagyi, S. Pathak, D. Melillo, 1991, Anticancer research.

Synthesis of [C2H3]methotrexate and [C2H3]7-hydroxymethotrexate

D. Dean, D. Melillo, C. Elmore, 2002 .

Synthesis and applications of isotopically labelled compounds 1997 : proceedings of the Sixth International Symposium, Philadelphia, USA, 14-18 September 1997

D. Melillo, J. Heys, 1998 .

Synthesis of two non-peptidyl GnRH receptor antagonists via [14C]carbonylation

R. DeVita, D. Dean, D. Melillo, 2003 .

Use of fluorous and solid-phase electrophiles as scavengers for excess amine in the preparation of sulfur-35 labelled radioligands

D. Dean, D. Melillo, C. Elmore, 2005 .