M. Karbarz

发表

Enzymatic Synthesis of Lipid A Molecules with Four Amide-linked Acyl Chains

Suzanne R. Kalb, A. Williams, C. Raetz, 2004, Journal of Biological Chemistry.

Preclinical Characterization of the FAAH Inhibitor JNJ-42165279.

Sandy J. Wilson, M. Karbarz, S. Chaplan, 2015, ACS medicinal chemistry letters.

The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors.

Sandy J. Wilson, M. Karbarz, S. Chaplan, 2016, Bioorganic & medicinal chemistry letters.

A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers.

J. Leeds, P. Conley, M. Karbarz, 2020, Blood advances.

Safety, pharmacokinetics, and reversal of apixaban anticoagulation with andexanet alfa.

J. Leeds, P. Conley, M. Karbarz, 2017, Blood advances.

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial Demonstrating Reversal Of Rivaroxaban-Induced Anticoagulation In Healthy Subjects By Andexanet Alfa (PRT064445), An Antidote For Fxa Inhibitors

S. Connolly, P. Conley, M. Karbarz, 2013 .

Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate.

Sandy J. Wilson, M. Karbarz, S. Chaplan, 2012, ACS medicinal chemistry letters.

Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

Sandy J. Wilson, Jiejun Wu, M. Karbarz, 2009, Anesthesia and analgesia.

Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase.

Sandy J. Wilson, Jiejun Wu, K. Pattabiraman, 2008, Bioorganic & medicinal chemistry letters.

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors.

C. Haynes, A. Creagh, P. Conley, 2018, Blood advances.

Abstract 10: Randomized, Double-Blind, Placebo-Controlled Single Ascending Dose Pharmacokinetic and Pharmacodynamic Study of PRT064445, a Universal Antidote for Factor Xa Inhibitors

M. Karbarz, M. Crowther, J. Curnutte, 2013 .

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.

Sandy J. Wilson, M. Karbarz, S. Chaplan, 2014, Bioorganic & medicinal chemistry letters.

Monday, 27 August 2012

V. V. Ivanenko, E. A. Medvedeva, Michail I. Papafaklis, 2012 .

Interaction of group IA phospholipase A2 with metal ions and phospholipid vesicles probed with deuterium exchange mass spectrometry.

Virgil L. Woods, E. Dennis, J. Burke, 2008, Biochemistry.

MsbA Transporter-dependent Lipid A 1-Dephosphorylation on the Periplasmic Surface of the Inner Membrane

Xiaoyuan Wang, C. Raetz, M. Karbarz, 2004, Journal of Biological Chemistry.

Purification and Characterization of the Lipid A 1-Phosphatase LpxE of Rhizobium leguminosarum*

C. Raetz, M. Karbarz, David A. Six, 2009, Journal of Biological Chemistry.

Expression Cloning and Characterization of the C28 Acyltransferase of Lipid A Biosynthesis in Rhizobium leguminosarum *

C. Raetz, S. Basu, M. Karbarz, 2002, The Journal of Biological Chemistry.

Periplasmic Cleavage and Modification of the 1-Phosphate Group of Helicobacter pylori Lipid A*

Xiaoyuan Wang, C. Raetz, M. Karbarz, 2004, Journal of Biological Chemistry.

Expression Cloning and Biochemical Characterization of a Rhizobium leguminosarum Lipid A 1-Phosphatase*

Suzanne R. Kalb, C. Raetz, M. Karbarz, 2003, Journal of Biological Chemistry.

A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa

P. Conley, P. Luan, M. Karbarz, 2013, Nature Medicine.

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase.

M. Karbarz, S. Chaplan, J. Keith, 2014, Bioorganic & medicinal chemistry letters.

Heteroarylureas with Fused Bicyclic Diamine Cores as Inhibitors of Fatty Acid Amide Hydrolase.

M. Karbarz, S. Chaplan, J. Keith, 2020, Bioorganic & medicinal chemistry letters.

Origin of the 2-amino-2-deoxy-gluconate unit in Rhizobium leguminosarum lipid A. Expression cloning of the outer membrane oxidase LpxQ.

Suzanne R. Kalb, C. Raetz, M. Karbarz, 2003, The Journal of biological chemistry.

Heteroaryl urea inhibitors of fatty acid amide hydrolase: structure-mutagenicity relationships for arylamine metabolites.

M. Karbarz, S. Chaplan, N. Hawryluk, 2012, Bioorganic & medicinal chemistry letters.

Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate.

M. Karbarz, S. Chaplan, J. Keith, 2012, ACS medicinal chemistry letters.