Dawei Chen

发表

Identification of Macrodomain Proteins as Novel O-Acetyl-ADP-ribose Deacetylases*

John M Denu, Frank von Delft, Opher Gileadi, 2011, The Journal of Biological Chemistry.

Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein.

Yuyang Jiang, Yuan Li, Dawei Chen, 2022, European journal of medicinal chemistry.

Basis for the equilibrium constant in the interconversion of l-lysine and l-beta-lysine by lysine 2,3-aminomutase.

P. Frey, Dawei Chen, Justinn M Tanem, 2007, Biochimica et biophysica acta.

Identification of structural and catalytic classes of highly conserved amino acid residues in lysine 2,3-aminomutase.

P. Frey, D. Ringe, Dawei Chen, 2006, Biochemistry.

Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase.

P. Frey, B. Hoffman, C. Walsby, 2003, Journal of the American Chemical Society.

Phenylalanine Hydroxylase from Chromobacterium violaceum

P. Frey, Dawei Chen, 1998, The Journal of Biological Chemistry.

Discovery of 2-(1-(3-(4-Chloroxyphenyl)-3-oxo- propyl)pyrrolidine-3-yl)-1H-benzo[d]imidazole-4-carboxamide: A Potent Poly(ADP-ribose) Polymerase (PARP) Inhibitor for Treatment of Cancer

Yuyang Jiang, Dawei Chen, Cunlong Zhang, 2019, Molecules.

Epimerization at carbon-5' of (5'R)-[5'-2H]adenosylcobalamin by ribonucleoside triphosphate reductase: cysteine 408-independent cleavage of the Co-C5' bond.

P. Frey, J. Stubbe, Dawei Chen, 2003, Biochemistry.

Orphan Macrodomain Protein (Human C6orf130) Is an O-Acyl-ADP-ribose Deacylase

J. Denu, B. Volkman, I. Ahel, 2011, The Journal of Biological Chemistry.

Discovery of triazolo [1,5-a] pyridine derivatives as novel JAK1/2 inhibitors.

X. Zhai, Yuyang Jiang, Dawei Chen, 2020, Bioorganic & medicinal chemistry letters.

Synergic fabrication of folic acid-targeted hyperbranched polymer (HBP)-modified pH-response drug delivery system for the treatment of breast cancer

Dawei Chen, Dongxu Feng, Wei Wu, 2023, Process Biochemistry.

Discovery of the PARP (poly ADP-ribose polymerase) inhibitor 2-(1-(4,4-difluorocyclohexyl)piperidin-4-yl)-1H-benzo[d]imidazole-4-carboxamide for the treatment of cancer.

X. Zhai, Yuyang Jiang, Dawei Chen, 2021, Bioorganic chemistry.

Synthesis and Anti-Influenza Virus Effects of Novel Substituted Polycyclic Pyridone Derivatives Modified from Baloxavir.

Yuyang Jiang, Dawei Chen, Cunlong Zhang, 2021, Journal of medicinal chemistry.

Orphan Macrodomain Protein (Human C6orf130) Is an O-Acyl-ADP-ribose Deacylase

J. Denu, B. Volkman, F. Peterson, 2011, The Journal of Biological Chemistry.

How an enzyme tames reactive intermediates: positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy.

P. Frey, B. Hoffman, C. Walsby, 2006, Journal of the American Chemical Society.