Abhishek D Garg

P. Agostinis, Abhishek D Garg, 2014, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Coordination of stress, Ca2+, and immunogenic signaling pathways by PERK at the endoplasmic reticulum

P. Agostinis, Abhishek D Garg, A. V. van Vliet, 2016, Biological chemistry.

Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A

P. Agostinis, A. Dudek, Abhishek D Garg, 2013, Cell Death and Disease.

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

P. Vandenabeele, P. Agostinis, C. Mathieu, 2013, Autophagy.

Autophagy-dependent suppression of cancer immunogenicity and effector mechanisms of innate and adaptive immunity

P. Agostinis, A. Dudek, Abhishek D Garg, 2013, Oncoimmunology.

DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown

P. Vandenabeele, P. Agostinis, Abhishek D Garg, 2011, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Editorial: Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality

P. Agostinis, Abhishek D Garg, 2016, Front. Immunol..

Cell Death and PDT-Based Photooxidative (Phox) Stress

P. Agostinis, Abhishek D Garg, 2013 .

Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma

L. Boon, P. Agostinis, Marco B. E. Schaaf, 2017, Oncoimmunology.

The PERKs of damage-associated molecular patterns mediating cancer immunogenicity: From sensor to the plasma membrane and beyond.

S. Martin, P. Agostinis, Abhishek D Garg, 2015, Seminars in cancer biology.

BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis

P. Agostinis, W. Annaert, J. J. van den Oord, 2021, The EMBO journal.

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity.

M. Bertrand, P. Vandenabeele, G. Berx, 2016, Cell reports.

Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

P. Agostinis, P. Cartron, Abhishek D Garg, 2017, Oncoimmunology.

Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal

P. Vandenabeele, P. Agostinis, P. D. de Witte, 2015, Oncotarget.

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells

P. Agostinis, C. Mathieu, Abhishek D Garg, 2018, Oncotarget.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Melanoma immunotherapy

P. Agostinis, Abhishek D Garg, A. Dudek-Perić, 2015, Oncoscience.

Toad skin-secretions: Potent source of pharmacologically and therapeutically significant compounds

Abhishek D Garg, R. Hippargi, Amit N. Gandhare, 2007 .

Mapping the recovery of critically ill COVID19 patients by high-dimensional profiling identifies longitudinal blood immunotypes

Y. Saeys, E. Wauters, D. Panovska, 2020 .

Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes

P. Agostinis, C. Mathieu, D. Eizirik, 2014, Diabetes.

Extracellular ATP and P2X7 receptor exert context-specific immunogenic effects after immunogenic cancer cell death

P. Vandenabeele, P. Agostinis, Abhishek D Garg, 2016, Cell Death and Disease.

Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin.

L. Boon, P. Agostinis, J. Gołąb, 2015, Cancer research.

The Interface of Tumour-Associated Macrophages with Dying Cancer Cells in Immuno-Oncology

M. Mazzone, J. V. Van Ginderachter, Abhishek D Garg, 2022, Cells.

DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

A. Vral, R. Raedt, C. Bachert, 2022, Cell death & disease.

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim.

P. Agostinis, Sanjeev Gupta, M. Dewaele, 2013, Biochemical and biophysical research communications.

Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation

P. Agostinis, Abhishek D Garg, N. Rufo, 2016, Cell Death and Differentiation.

An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAFV600E inhibitor-resistant metastatic melanoma cells

P. Agostinis, Shaun Martin, P. Vangheluwe, 2017, Autophagy.

Autophagy: shaping the tumor microenvironment and therapeutic response.

P. Agostinis, Abhishek D Garg, H. Maes, 2013, Trends in molecular medicine.

Defining the role of the tumor vasculature in antitumor immunity and immunotherapy

P. Agostinis, Marco B. E. Schaaf, Abhishek D Garg, 2018, Cell Death & Disease.

Immunogenic cell death and DAMPs in cancer therapy

Abhishek D. Garg, Patrizia Agostinis, Dmitri V. Krysko, 2012, Nature Reviews Cancer.

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

F. Marincola, P. Vandenabeele, S. Loi, 2020, Journal for ImmunoTherapy of Cancer.

Computed determination of the in vitro optimal chemocombinations of sphaeropsidin A with chemotherapeutic agents to combat melanomas

W. Berger, B. Dejaegher, V. Mathieu, 2017, Cancer Chemotherapy and Pharmacology.

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

Susan M. Schlenner, P. Vandenabeele, J. Parys, 2020, Cells.

Immunogenomic, single-cell and spatial dissection of CD8+T cell exhaustion reveals critical determinants of cancer immunotherapy

D. Lambrechts, F. De Smet, A. Liston, 2021, bioRxiv.

Trial watch: dendritic cell vaccination for cancer immunotherapy

L. Zitvogel, L. Galluzzi, G. Kroemer, 2019, Oncoimmunology.

Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy

P. Agostinis, I. Adkins, Abhishek D Garg, 2014, Oncoimmunology.

Inducers of immunogenic cancer cell death.

D. de Ruysscher, P. Agostinis, A. Dudek, 2013, Cytokine & growth factor reviews.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

P. Agostinis, J. Piette, R. Rizzuto, 2012, Cell Death and Differentiation.

Antimicrobial activity of skin secretions isolated from Indian toad, Bufo melanostictus Schneider 1799

Abhishek D Garg, R. Hippargi, Amit N. Gandhare, 2007 .

Cellular and molecular features related to exceptional therapy response and extreme long‐term survival in glioblastoma

R. Sciot, P. Agostinis, F. De Smet, 2023, Cancer medicine.

Transplantation and Damage‐Associated Molecular Patterns (DAMPs)

P. Agostinis, S. Gasser, Abhishek D Garg, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Orientation of Preclinical Research in Ovarian Cancer

P. Agostinis, I. Vergote, A. Coosemans, 2017, International Journal of Gynecologic Cancer.

Immature, Semi-Mature, and Fully Mature Dendritic Cells: Toward a DC-Cancer Cells Interface That Augments Anticancer Immunity

P. Agostinis, Shaun Martin, A. Dudek, 2013, Front. Immunol..

A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer

P. Neven, C. Desmedt, D. Lambrechts, 2021, Nature Medicine.

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

L. Zitvogel, L. Galluzzi, G. Kroemer, 2020, Oncoimmunology.

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

L. Zitvogel, L. Galluzzi, G. Kroemer, 2017, Oncoimmunology.

Photodynamic therapy: illuminating the road from cell death towards anti-tumour immunity

P. Agostinis, D. Nowis, J. Gołąb, 2010, Apoptosis.

Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade glioma

Abhishek D. Garg, Lien Vandenberk, Tina Verschuere, 2016, Science Translational Medicine.

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

P. Agostinis, S. V. Van Gool, Abhishek D Garg, 2015, Oncoimmunology.

Stem Cell Therapeutics: Exploring Newer Alternatives to Human Embryonic Stem Cells

Abhishek D Garg, 2007 .

DAMP—Induced Allograft and Tumor Rejection: The Circle Is Closing

P. Agostinis, S. Gasser, Abhishek D Garg, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Consensus guidelines for the detection of immunogenic cell death

P. Vandenabeele, S. Loi, L. Zitvogel, 2014, Oncoimmunology.

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

P. Vandenabeele, P. Agostinis, J. Gołąb, 2012, The EMBO journal.

Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses

P. Agostinis, Abhishek D Garg, 2017, Immunological reviews.

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation.

B. Lambrecht, P. Vandenabeele, C. Bachert, 2011, Trends in immunology.

ER Stress and Inflammation

P. Vandenabeele, Abhishek D Garg, D. Krysko, 2012 .

Trial watch: Dendritic cell-based anticancer immunotherapy

L. Zitvogel, L. Galluzzi, G. Kroemer, 2017, Oncoimmunology.

Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy

L. Boon, C. Ries, S. Janssens, 2021, bioRxiv.

In Vitro Studies on Erythrosine-Based Photodynamic Therapy of Malignant and Pre-Malignant Oral Epithelial Cells

W. Bonass, Abhishek D Garg, M. I. Ahmed, 2012, PloS one.

Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy

R. Kiss, L. Boon, P. Agostinis, 2017, Scientific Reports.

Early memory differentiation and cell death resistance in T cells predicts melanoma response to sequential anti-CTLA4 and anti-PD1 immunotherapy

S. Tejpar, Abhishek D Garg, D. Borràs, 2021, Genes & Immunity.

ER stress-induced inflammation: does it aid or impede disease progression?

P. Vandenabeele, P. Agostinis, Abhishek D Garg, 2012, Trends in molecular medicine.

Cancer immunogenicity, danger signals, and DAMPs: What, when, and how?

P. Agostinis, A. Dudek, Abhishek D Garg, 2013, BioFactors.

The IRE1 Inhibitor Kira6 Curtails The Inflammatory Trait Of Immunogenic Anticancer Treatments By Targeting Hsp60 Independent Of IRE1

L. Alexopoulos, S. Janssens, R. Derua, 2020, bioRxiv.

High dimensional profiling identifies specific immune types along the recovery trajectories of critically ill COVID19 patients

Y. Saeys, F. De Smet, S. Van Gassen, 2021, Cellular and Molecular Life Sciences.

Immunogenic cell death and its therapeutic or prognostic potential in high-grade glioma

P. Agostinis, F. De Smet, Abhishek D Garg, 2022, Genes & Immunity.

Type I interferons and endoplasmic reticulum stress in health and disease

Abhishek D Garg, J. Sprooten, 2019, International Review of Cell and Molecular Biology.

Autophagy, a major adaptation pathway shaping cancer cell death and anticancer immunity responses following photodynamic therapy

P. Agostinis, Abhishek D Garg, H. Maes, 2015, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells.

S. Martin, P. Agostinis, J. Swinnen, 2015, Biochemical pharmacology.

Autophagy Induced by Photodynamic Therapy (PDT): Shaping Resistance Against Cell Death and Anti-Tumor Immunity

P. Agostinis, Abhishek D Garg, 2015 .

Establishing a Unified COVID-19 “Immunome”: Integrating Coronavirus Pathogenesis and Host Immunopathology

D. Lambrechts, C. Wouters, B. Weynand, 2020, Frontiers in Immunology.

Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages

L. Boon, C. Ries, S. Janssens, 2022, Cancer research.

The Use of Toll-like Receptor 4 Agonist to Reshape the Immune Signature in Ovarian Cancer.

I. Vergote, A. Coosemans, G. Verbist, 2016, Anticancer research.

Danger signalling during cancer cell death: origins, plasticity and regulation

S. Martin, P. Agostinis, J. Gołąb, 2013, Cell Death and Differentiation.

Immunogenic cell death.

P. Agostinis, Abhishek D Garg, A. Dudek-Perić, 2015, The International journal of developmental biology.

Targeting the hallmarks of cancer with therapy-induced endoplasmic reticulum (ER) stress

P. Agostinis, Abhishek D Garg, H. Maes, 2014, Molecular & cellular oncology.

Immunology of Cell Death in Cancer Immunotherapy

L. Galluzzi, Abhishek D Garg, 2021, Cells.

Melphalan, Antimelanoma Immunity, and Inflammation--Response.

P. Agostinis, Abhishek D Garg, A. Dudek-Perić, 2015, Cancer research.

The emergence of phox-ER stress induced immunogenic apoptosis

P. Vandenabeele, P. Agostinis, Abhishek D Garg, 2012, Oncoimmunology.

Contribution of ER Stress to Immunogenic Cancer Cell Death

P. Vandenabeele, P. Agostinis, J. Gołąb, 2012 .

Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses.

P. Agostinis, P. Salvén, Abhishek D Garg, 2020, Methods in enzymology.

Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer

D. Timmerman, L. Boon, P. Agostinis, 2021, Journal for ImmunoTherapy of Cancer.

Damage-associated Molecular Patterns: revealing the molecular communication between dying cancer cells and the immune system

Abhishek D Garg, 2012 .

Apoptotic cell death in disease—Current understanding of the NCCD 2023

S. Lipton, A. Ciechanover, T. Luedde, 2023, Cell Death & Differentiation.

In Vitro Generation of Murine Dendritic Cells for Cancer Immunotherapy: An Optimized Protocol.

P. Agostinis, I. Vergote, A. Coosemans, 2016, Anticancer research.

Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway

P. Agostinis, J. Swinnen, N. Khan, 2017, Oncotarget.

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton

P. Vandenabeele, P. Agostinis, Abhishek D Garg, 2014, Cell Death and Disease.

Diversifying the platinum-based chemotherapy toolkit for immunogenic cancer cell death

P. Agostinis, Abhishek D Garg, 2020, Oncotarget.

PERK IS REQUIRED AT THE ER-TO-MITOCHONDRIA CONTACT SITES TO CONVEY APOPTOSIS FOLLOWING ROS-MEDIATED ER STRESS

P. Agostinis, J. Piette, Sanjeev Gupta, 2012 .

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

J. Raes, Y. Saeys, D. Lambrechts, 2020, Nature Communications.