H. Treutlein

发表

Sequence specificity in the dimerization of transmembrane alpha-helices.

D. Engelman, J. Zhang, M. Lemmon, 1992, Biochemistry.

Conformational analysis of thiopeptides: free energy calculations on the effects of thio-substitutions on the conformational distributions of alanine dipeptides.

A. Burgess, H. Treutlein, T. T. Tran, 2001, Journal of molecular graphics & modelling.

Electric field effects on insulin chain-B conformation.

Irene Yarovsky, H. Treutlein, I. Yarovsky, 2005, The journal of physical chemistry. B.

Effect of frequency on insulin response to electric field stress.

H. Treutlein, I. Yarovsky, A. Budi, 2007, The journal of physical chemistry. B.

Comparative study of insulin chain-B in isolated and monomeric environments under external stress.

H. Treutlein, I. Yarovsky, A. Budi, 2008, The journal of physical chemistry. B.

A method for computational combinatorial peptide design of inhibitors of Ras protein.

J Zeng, H. Treutlein, J. Zeng, 1999, Protein engineering.

Computational Identification of Antibody Epitopes on the Dengue Virus NS1 Protein

S. Mahler, P. Young, H. Treutlein, 2017, Molecules.

Antibody Recognition of Shiga Toxins (Stxs): Computational Identification of the Epitopes of Stx2 Subunit A to the Antibodies 11E10 and S2C4

Xiaoyan Zeng, Yongjun Jiao, H. Treutlein, 2014, PloS one.

Design of inhibitors of Ras--Raf interaction using a computational combinatorial algorithm.

B Catimel, J Zeng, T. Nheu, 2001, Protein engineering.

Protein‐protein recognition: An experimental and computational study of the R89K mutation in Raf and its effect on Ras binding

Thomas Simonson, Hiroshi Maruta, T. Simonson, 2008, Protein science : a publication of the Protein Society.

Chromophore-protein interactions and the function of the photosynthetic reaction center: a molecular dynamics study.

M Karplus, K Schulten, J Deisenhofer, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Helix-helix interactions inside membranes

D. Engelman, A. Brunger, J. Hunt, 1995 .

Molecular dynamics simulations of a fibrillogenic peptide derived from apolipoprotein C-II.

G. Howlett, H. Treutlein, I. Yarovsky, 2007, Biophysical chemistry.

Cytoskeleton in Tumor Cells A Novel Class of Anticancer Compounds Targets the Actin

Vanessa B. Sequeira, Paula R. B. B. Nascimento, Stephen J. Palmer, 2013 .

The glycophorin A transmembrane domain dimer: sequence-specific propensity for a right-handed supercoil of helices.

D. Engelman, A. Brünger, A. Brunger, 1992, Biochemistry.

PEPCAT—A new tool for conformational analysis of peptides

A. Burgess, H. Treutlein, E. Minasian, 2000 .

MOLECULAR DYNAMICS SIMULATION OF THE PRIMARY PROCESSES IN THE PHOTOSYNTHETIC REACTION CENTER OF Rhcdopseudomonas viridis

M. Karplus, J. Deisenhofer, K. Schulten, 2022 .

Electron Conduction Along Aliphatic Chains

K. Schulten, H. Treutlein, R. Bittl, 1985 .

A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.

Sanjay Kumar, H. Treutlein, A. Rathi, 2020, Bioorganic & medicinal chemistry.

Conversion of the biological specificity of murine to human leukemia inhibitory factor by replacing 6 amino acid residues.

M. Layton, H. Treutlein, C. Owczarek, 1994, The Journal of biological chemistry.

Molecular Dynamics Simulation of the Primary Processes in the Photosynthetic Reaction Center of Rhodopseudomonas Viridis

Klaus Schulten, C. Niedermeier, Herbert R. Treutlein, 1988 .

A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

I. Kola, P. Hertzog, H. Treutlein, 2001, Cytogenetic and Genome Research.

Computational Prediction of the Epitopes of HA1 Protein of Influenza Viruses to its Neutralizing Antibodies

Xiaoyan Zeng, Yongjun Jiao, H. Treutlein, 2018, Antibodies.

Dissecting the EphA3/Ephrin-A5 Interactions Using a Novel Functional Mutagenesis Screen*

Ke Chen, Andrew W Boyd, Martin Lackmann, 2004, Journal of Biological Chemistry.

Discovery of 2-(alpha-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS.

A. Wilks, H. Treutlein, E. Fantino, 2009, Bioorganic & medicinal chemistry letters.

Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor

R. Jorissen, A. Burgess, C. Ward, 2008, Protein science : a publication of the Protein Society.

Interaction of Granulocyte Colony-stimulating Factor (G-CSF) with Its Receptor

T. Boone, T. Osslund, H. Treutlein, 1999, The Journal of Biological Chemistry.

Conformational analysis of thiopeptides: derivation of sp2 sulfur parameters for the CFF91 force field

Herbert R. Treutlein, Antony W. Burgess, Tran Trung Tran, 2001, J. Comput. Chem..

A dimerization motif for transmembrane α–helices

D. Engelman, P. Adams, A. Brünger, 1994, Nature Structural Biology.

Quantum Simulations of Materials and Biological Systems

Ruiqin Q. Zhang, H. Treutlein, Jun Zeng, 2012 .

Identification of a Ligand-binding Site on the Granulocyte Colony-stimulating Factor Receptor by Molecular Modeling and Mutagenesis*

D. Smith, H. Treutlein, J. Layton, 1997, The Journal of Biological Chemistry.

Synthesis, X-ray crystallographic structures of thio substituted N-acetyl N'-methylamide alanine and evaluation of sp sulfur parameters of the CFF91 force field.

A. Burgess, H. Treutlein, T. T. Tran, 2001, The journal of peptide research : official journal of the American Peptide Society.

Systematic comparison of empirical forcefields for molecular dynamic simulation of insulin.

Nevena Todorova, Irene Yarovsky, H. Treutlein, 2008, The journal of physical chemistry. B.

Structure‐Function analysis of human IL‐6: Identification of two distinct regions that are important for receptor binding

L. D. Ward, R. Simpson, K. Yasukawa, 1994, Protein science : a publication of the Protein Society.

Molecular dynamics simulations of the Ras:Raf and Rap:Raf complexes

J Zeng, T. Simonson, H. Treutlein, 1999, Proteins.

Point Mutants of c-Raf-1 RBD with Elevated Binding to v-Ha-Ras*

F. Walker, H. Treutlein, J. Zeng, 2000, The Journal of Biological Chemistry.

Disulfide Bond Structure and N-Glycosylation Sites of the Extracellular Domain of the Human Interleukin-6 Receptor*

R. Moritz, J. Eddes, A. Cole, 1999, The Journal of Biological Chemistry.

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.

J. Rossjohn, A. Wilks, H. Treutlein, 2006, Blood.

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs).

David M. Shackleford, Christopher J Burns, Susan A Charman, 2009, Bioorganic & medicinal chemistry letters.

Successful Computational Prediction of the S tructure-Activity Relationship of a Potent JAK2 Inhibitor

H. Treutlein, Michelle L. Styles, J. Zeng, 2008 .

Computational identification of epitopes in the glycoproteins of novel bunyavirus (SFTS virus) recognized by a human monoclonal antibody (MAb 4-5)

Li Zhang, Jun Zeng, Wenshuai Zhang, 2013, Journal of Computer-Aided Molecular Design.

LIF receptor‐gp130 interaction investigated by homology modeling: Implications for LIF binding

H. Treutlein, David K. Smith, 1998, Protein science : a publication of the Protein Society.

On-target action of anti-tropomyosin drugs regulates glucose metabolism

Nicole S. Bryce, J. Stehn, E. Hardeman, 2018, Scientific Reports.

A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells.

Wolfgang Weninger, Melissa Desouza, Vanessa B. Sequeira, 2013, Cancer research.

Effect of external stresses on protein conformation: a computer modelling study

H. Treutlein, I. Yarovsky, A. Budi, 2004, European Biophysics Journal.

A dimerization motif for transmembrane alpha-helices.

A T Brünger, P D Adams, D. Engelman, 1994, Nature structural biology.

A potent human interleukin-4 antagonist stimulates the proliferation of murine cells expressing the human interleukin-4 binding chain.

A. Burgess, I. Davis, H. Treutlein, 1995, Growth factors.

Predicting sequences and structures of MHC-binding peptides: a computational combinatorial approach

Jun Zeng, Herbert R. Treutlein, George B. Rudy, 2001, J. Comput. Aided Mol. Des..

Homology modelling and 1H NMR studies of human leukaemia inhibitory factor

D K Smith, R. Norton, M. Layton, 1994, FEBS letters.

Modeling conformational changes in cyclosporin A

A. Burgess, M. Walkinshaw, H. Treutlein, 1995, Protein science : a publication of the Protein Society.

Identification of Ligand-binding Site III on the Immunoglobulin-like Domain of the Granulocyte Colony-stimulating Factor Receptor*

J. Venhorst, H. Treutlein, N. E. Hall, 2001, The Journal of Biological Chemistry.

Electrostatic Control of Electron Transfer in the Photosynthetic Reaction Center of Rhodopseudomonas viridis

J. Deisenhofer, K. Schulten, H. Michel, 1988 .

NOISE INDUCED LIMIT CYCLES OF THE BONHOEFFER-VAN DER POL MODEL OF NEURAL PULSES.

Klaus Schulten, Herbert R. Treutlein, K. Schulten, 1985 .

Protein flexibility: multiple molecular dynamics simulations of insulin chain B.

H. Treutlein, I. Yarovsky, A. Budi, 2006, Biophysical chemistry.

Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs

J. Stehn, E. Hardeman, P. Gunning, 2017, Molecular Cancer Therapeutics.

Effects of Thioamide Substitutions on the Conformation and Stability of α- and 310-Helices

Herbert R. Treutlein, Tran Trung Tran, A. Burgess, 2002 .

Conformational analysis of thiopeptides: (ϕ,ψ) maps of thio‐substituted dipeptides

Herbert R. Treutlein, Antony W. Burgess, Tran Trung Tran, 2001, J. Comput. Chem..

Designing amino acid residues with single-conformations.

A. Burgess, H. Treutlein, T. T. Tran, 2006, Protein engineering, design & selection : PEDS.

Effect of oxidation and mutation on the conformational dynamics and fibril assembly of amyloidogenic peptides derived from apolipoprotein C-II.

G. Howlett, H. Treutlein, I. Yarovsky, 2009, The journal of physical chemistry. B.

Dimerization of glycophorin A transmembrane helices: mutagenesis and modeling.

D. Engelman, A. Brünger, J. Hunt, 1993, Society of General Physiologists series.

Conformation of the Ras‐binding domain of Raf studied by molecular dynamics and free energy simulations

Thomas Simonson, Jun Zeng, T. Simonson, 1998, Proteins.

A model for the activation of the epidermal growth factor receptor kinase involvement of an asymmetric dimer?

A. Burgess, F. Walker, H. Treutlein, 1997, Biochemistry.

On-target action of anti-tropomyosin drugs regulates glucose metabolism

Nicole S. Bryce, J. Stehn, E. Hardeman, 2018, Scientific Reports.

Modeling the Epidermal Growth Factor—Epidermal Growth Factor Receptor L2 Domain Interaction: Implications for the Ligand Binding Process

R. Jorissen, A. Burgess, H. Treutlein, 2002, Journal of biomolecular structure & dynamics.

Simulation of helix association in membranes: modeling the glycophorin A transmembrane domain

Herbert R. Treutlein, Axel T. Brunger, A. T. Brunger, 1993, [1993] Proceedings of the Twenty-sixth Hawaii International Conference on System Sciences.

Noise-induced neural impulses

K. Schulten, H. Treutlein, 1986, European Biophysics Journal.