J. Berglund

发表

The genome sequence of the filamentous fungus Neurospora crassa

E. Mauceli, B. Birren, C. Nusbaum, 2003, Nature.

A comprehensive computational characterization of conserved mammalian intronic sequences reveals conserved motifs associated with constitutive and alternative splicing.

J. Berglund, R. Voelker, 2007, Genome research.

Alternative pre-mRNA splicing.

J. Berglund, Stacey D Wagner, Stacey D. Wagner, 2014, Methods in molecular biology.

The potential of engineered eukaryotic RNA‐binding proteins as molecular tools and therapeutics

J. Cleary, J. Berglund, Carl Shotwell, 2019, Wiley interdisciplinary reviews. RNA.

Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening

Eric T. Wang, E. Wang, J. Cleary, 2022, iScience.

Superoxide Dismutase Structures, Stability, Mechanism and Insights into the Human Disease Amyotrophic Lateral Sclerosis from Eukaryotic Thermophile Alvinella pompejana

Greg L. Hura, J. Tainer, E. Getzoff, 2009 .

Crystal Structure of NADP(H)-Dependent 1,5-Anhydro-d-fructose Reductase from Sinorhizobium morelense at 2.2 Å Resolution: Construction of a NADH-Accepting Mutant [Cu(OH)3(CH═CH2)] and Its Application in Rare Sugar Synthesis 1: Subtitle to Document

A. Scheidig, J. Berglund, Tresfore M. Dambe, 2007 .

Utilizing the GAAA tetraloop/receptor to facilitate crystal packing and structure determination of a CUG RNA helix

J. Berglund, J. Lohman, L. Coonrod, 2012 .

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice

Eric T. Wang, Lauren A. Laboissonniere, E. Wang, 2020, bioRxiv.

J. Berglund, M. B. Warf, 2007, RNA.

The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence.

M. Rosbash, J. Berglund, M. L. Fleming, 1998, RNA.

Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast.

P. Baumann, J. Berglund, R. Voelker, 2013, Genes & development.

CCG•CGG interruptions in high penetrance SCA8 families increase RAN translation and protein toxicity

Lauren A. Laboissonniere, S. Subramony, T. Ashizawa, 2021, bioRxiv.

Biological Efficacy and Toxicity of Diamidines in Myotonic Dystrophy Type 1 Models.

M. M. Khalifa, M. Nakamori, J. Berglund, 2015, Journal of medicinal chemistry.

RNA binding specificity of Drosophila muscleblind.

J. Berglund, R. Voelker, Devika P. Gates, 2008, Biochemistry.

Disease-associated inosine misincorporation into RNA hinders translation

Mark T. Handley, T. Begley, Q. Lin, 2022, Nucleic acids research.

The SF3b155 N-terminal domain is a scaffold important for splicing.

J. Berglund, Danielle M Cass, 2006, Biochemistry.

The structural basis of myotonic dystrophy from the crystal structure of CUG repeats.

Jeremy S Logue, B. Mooers, J. Berglund, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites.

S. Lietzke, C. Kundrot, J. Berglund, 1996, Structure.

Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis.

John A Tainer, Greg L. Hura, Greg L Hura, 2009, Journal of molecular biology.

Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules

J. Cleary, J. Berglund, Jana R. Jenquin, 2019, International journal of molecular sciences.

Synthesis of N-substituted aryl amidines by strong base activation of amines.

M. M. Khalifa, J. Berglund, M. Haley, 2015, Tetrahedron letters.

Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility*

M. N. Hinman, J. Berglund, R. Wek, 2017, The Journal of Biological Chemistry.

Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model

J. Berglund, P. Todd, M. Guenza, 2014, Nucleic acids research.

The splicing factor U2AF65 is functionally conserved in the thermotolerant deep-sea worm Alvinella pompejana.

S. Cary, David S. Shin, J. Berglund, 2005, Biochimica et biophysica acta.

RNA structure probing to characterize RNA–protein interactions on low abundance pre-mRNA in living cells

Eric T. Wang, E. Wang, M. Swanson, 2020, RNA.

Repeat-associated RNA structure and aberrant splicing.

J. Berglund, N. Johnson, M. Hale, 2019, Biochimica et biophysica acta. Gene regulatory mechanisms.

Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line

Cara T. Pager, Morgan A. Sammons, A. Payne, 2019, bioRxiv.

Role of RNA structure in regulating pre-mRNA splicing.

J Andrew Berglund, J. Berglund, M. B. Warf, 2010, Trends in biochemical sciences.

Transcriptome alterations in myotonic dystrophy skeletal muscle and heart.

Eric T. Wang, E. Wang, C. Burge, 2018, Human molecular genetics.

Computational approaches to mine publicly available databases.

Rodger B Voelker, William A Cresko, J Andrew Berglund, 2014, Methods in molecular biology.

Frequent Gain and Loss of Intronic Splicing Regulatory Elements during the Evolution of Vertebrates

J. Berglund, R. Voelker, H. Schaal, 2012, Genome biology and evolution.

The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC

M. Rosbash, R. Reed, J. Berglund, 1997, Cell.

A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition.

M. Rosbash, J. Berglund, N. Abovich, 1998, Genes & development.

Identification of motifs that function in the splicing of non-canonical introns

J. Berglund, R. Voelker, M. B. Warf, 2008, Genome Biology.

An Extended RNA Binding Site for the Yeast Branch Point-binding Protein and the Role of Its Zinc Knuckle Domains in RNA Binding*

J. Berglund, R. Voelker, S. Garrey, 2006, Journal of Biological Chemistry.

Combination Treatment of Erythromycin and Furamidine Provides Additive and Synergistic Rescue of Mis-Splicing in Myotonic Dystrophy Type 1 Models.

M. Nakamori, J. Berglund, Jana R. Jenquin, 2019, ACS pharmacology & translational science.

Reducing levels of toxic RNA with small molecules.

M. Nakamori, Wenli Wang, C. Thornton, 2013, ACS chemical biology.

Pentamidine reverses the splicing defects associated with myotonic dystrophy

M. Nakamori, C. Thornton, J. Berglund, 2009, Proceedings of the National Academy of Sciences.

Utilizing the GAAA tetraloop/receptor to facilitate crystal packing and determination of the structure of a CUG RNA helix.

J. Berglund, J. Lohman, L. Coonrod, 2012, Biochemistry.

Zebrafish mbnl mutants model physical and molecular phenotypes of myotonic dystrophy.

M. N. Hinman, K. Guillemin, J. Berglund, 2021, Disease models & mechanisms.

Zebrafish mbnl mutants model physical and molecular phenotypes of myotonic dystrophy

M. N. Hinman, K. Guillemin, J. Berglund, 2019, bioRxiv.

Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors

Stephanie J. Culler, C. Smolke, K. Hoff, 2010, Nucleic acids research.

The four Zn fingers of MBNL1 provide a flexible platform for recognition of its RNA binding elements

J. Berglund, Paul Barber, Devika P. Gates, 2011, BMC Molecular Biology.

An engineered RNA binding protein with improved splicing regulation

Eric T. Wang, E. Wang, J. Berglund, 2018, Nucleic acids research.

Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy

Eric T. Wang, E. Wang, C. Thornton, 2016, PLoS genetics.

Conservation of context-dependent splicing activity in distant Muscleblind homologs

Eric T. Wang, E. Wang, J. Berglund, 2016, Nucleic acids research.

Combinatorial Mutagenesis of MBNL1 Zinc Fingers Elucidates Distinct Classes of Regulatory Events

Eric T. Wang, E. Wang, J. Berglund, 2012, Molecular and Cellular Biology.

Actinomycin D Specifically Reduces Expanded CUG Repeat RNA in Myotonic Dystrophy Models.

M. Nakamori, J. Berglund, Adam Struck, 2015, Cell reports.

CCG•CGG interruptions in high‐penetrance SCA8 families increase RAN translation and protein toxicity

Lauren A. Laboissonniere, T. Ashizawa, C. Gomez, 2021, EMBO molecular medicine.

Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms.

M. Nakamori, G. Xia, J. Berglund, 2018, ACS chemical biology.

Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy

M. Nakamori, J. Cleary, J. Berglund, 2023, bioRxiv.

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels

Eric T. Wang, E. Wang, M. Nakamori, 2019, Proceedings of the National Academy of Sciences.

MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing

J. Berglund, R. Voelker, Devika P. Gates, 2010, Nucleic acids research.

Recognition of RNA Branch Point Sequences by the KH Domain of Splicing Factor 1 (Mammalian Branch Point Binding Protein) in a Splicing Factor Complex

Alan D. Frankel, M. Rosbash, A. Frankel, 2001, Molecular and Cellular Biology.

Transposition of two amino acids changes a promiscuous RNA binding protein into a sequence-specific RNA binding protein.

J. Berglund, S. Garrey, Anica M Wandler, 2007, RNA.

Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines.

M. Rosbash, J. Berglund, M Rosbash, 2001, RNA.

The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing

J Andrew Berglund, P. V. von Hippel, J. Berglund, 2009, Proceedings of the National Academy of Sciences.

A high affinity binding site for the HIV-1 nucleocapsid protein.

M. Rosbash, J. Berglund, B. Charpentier, 1997, Nucleic acids research.

MBNL1 and RBFOX1 co-regulate alternative splicing events transcriptome-wide through a conserved buffering mechanism

Eric T. Wang, E. Wang, J. Berglund, 2021, bioRxiv.

Autoregulated Splicing of muscleblind-like 1 (MBNL1) Pre-mRNA*

J. Berglund, L. Coonrod, Devika P. Gates, 2011, The Journal of Biological Chemistry.

Zebrafish mbnl mutants model molecular and physical phenotypes of human MBNL loss of function disorders

M. N. Hinman, K. Guillemin, J. Berglund, 2019 .

Individual transcriptomic response to strength training for patients with myotonic dystrophy type 1

J. Cleary, J. Berglund, H. Shorrock, 2023, JCI insight.

Two ways to misregulate mRNAs in myotonic dystrophy

J. Berglund, R. Voelker, Rodger B Voelker, 2010, Nature Structural &Molecular Biology.

Zebrafish mbnl mutants model physical and molecular phenotypes of 1 myotonic dystrophy 2

K. Guillemin, J. Berglund, Melissa N. Hinman, 2020 .

Autoregulated Splicing of muscleblind-like 1 (MBNL1) Pre-mRNA*

J. Berglund, L. Coonrod, Devika P. Gates, 2011, The Journal of Biological Chemistry.