Y. Hayakawa

Y. Hayakawa, M. Honma, Y. Hayakawa, 2007, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Effect of taurine on serum trehalase activity in the American cockroach, Periplaneta americana

Y. Hayakawa, R. Downer, A. Jahagirdar, 1988 .

Studies on the isotetracenone antibiotics. II. Kerriamycins A, B and C, new antitumor antibiotics.

Y. Hayakawa, H. Seto, N. Ōtake, 1985, The Journal of antibiotics.

Structure of Apoptolidin, a Specific Apoptosis Inducer in Transformed Cells

Y. Hayakawa, H. Seto, Ken-Ichi Fujita, 1998 .

Relative and absolute configuration of versipelostatin, a down-regulator of molecular chaperone GRP78 expression.

K. Shin‐ya, Y. Hayakawa, K. Furihata, 2007, Organic letters.

Legioliulin, a new isocoumarin compound responsible for blue-white autofluorescence in Legionella (Fluoribacter) dumoffii under long-wavelength UV light.

Haruo Watanabe, Y. Hayakawa, F. Kura, 2004, Biochemical and biophysical research communications.

Structures of stealthins A and B, new free radical scavengers of microbial origin

K. Shin‐ya, Y. Hayakawa, H. Seto, 1992 .

Structure of a new antibiotic roseophilin

Y. Hayakawa, H. Seto, K. Furihata, 1992 .

Structure of mescengricin, a novel neuronal cell protecting substance produced by Streptomyces griseoflavus

K. Shin‐ya, Y. Hayakawa, H. Seto, 1997 .

Isolation and structural elucidation of pyridoxatin, a free radical scavenger of microbial origin.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1991, The Journal of antibiotics.

Structure of a new microbial metabolite, neuchromenin

Y. Hayakawa, H. Seto, Hiroshi Yamamoto, 1996 .

A new depsipeptide antibiotic, citropeptin.

M. Nakagawa, Y. Hayakawa, H. Seto, 1990, Agricultural and biological chemistry.

A new depsipeptide antibiotic, variapeptin.

M. Nakagawa, Y. Hayakawa, H. Seto, 1990, Agricultural and biological chemistry.

Novel antibiotics pyrisulfoxin A and B produced by Streptomyces californicus.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1999, The Journal of antibiotics.

Oximidines I and II: Novel Antitumor Macrolides from Pseudomonas sp.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1999, The Journal of organic chemistry.

Thioviridamide, a Novel Apoptosis Inducer in Transformed Cells from Streptomyces olivoviridis

K. Shin‐ya, Y. Hayakawa, K. Nagai, 2006, The Journal of Antibiotics.

FERMENTATION , ISOLATION AND BIOLOGICAL ACTIVITY

Y. Hayakawa, H. Seto, A. Shimazu, 2006 .

A Novel Neuronal Cell Protecting Substance Mescengricin Produced by Streptomyces griseoflavus

K. Shin‐ya, Y. Hayakawa, H. Seto, 2000, Journal of Asian natural products research.

Studies on new antitumor antibiotics, leptofuranins A, B, C and D.I. Taxonomy, fermentation, isolation and biological activities.

K. Shin‐ya, Y. Hayakawa, T. Kuzuyama, 1996, The Journal of antibiotics.

Quinolidomicins A1, A2 and B1, novel 60-membered macrolide antibiotics. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1993, The Journal of antibiotics.

Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity.

Y. Hayakawa, H. Seto, A. Shimazu, 1991, The Journal of antibiotics.

Effect on tumor cells of blocking survival response to glucose deprivation.

Takashi Tsuruo, Hae-Ryong Park, Kazuo Shin-ya, 2004, Journal of the National Cancer Institute.

Studies on viridenomycin, a novel 24-membered macrocyclic polyene lactam antibiotic.

M. Nakagawa, Y. Hayakawa, H. Seto, 1992, The Journal of antibiotics.

Structure of viridenomycin

M. Nakagawa, Y. Hayakawa, H. Seto, 1991 .

Relative and absolute stereochemistry of quinadoline B, an inhibitor of lipid droplet synthesis in macrophages.

S. Ōmura, H. Homma, Y. Hayakawa, 2008, Organic letters.

Structure of kaitocephalin, a novel glutamate receptor antagonist produced by Eupenicillium shearii

K. Shin‐ya, Y. Hayakawa, H. Seto, 1997 .

Synthesis of the proposed structure and revision of stereochemistry of kaitocephalin

K. Shin‐ya, Y. Hayakawa, T. Kitahara, 2002 .

The structure of benthocyanin A. A new free radical scavenger of microbial origin

K. Shin‐ya, J. Clardy, Y. Hayakawa, 1991 .

Isolation and structural elucidation of antioxidative agents, antiostatins A1 to A4 and B2 to B5.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1990, The Journal of antibiotics.

Studies on free radical scavenging substances from microorganisms. I. Carazostatin, a new free radical scavenger produced by Streptomyces chromofuscus DC 118.

Y. Hayakawa, H. Kawai, S. Kato, 1989, The Journal of antibiotics.

Isolation and structure elucidation of novel neuronal cell protecting substances, carbazomadurins A and B produced by Actinomadura madurae.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1997, The Journal of antibiotics.

Synthesis and structure revision of tyroscherin, and bioactivities of its stereoisomers against IGF-1-dependent tumor cells

Y. Hayakawa, K. Ishigami, T. Kitahara, 2009 .

Carquinostatin B, a new neuronal cell-protecting substance produced by Streptomyces exfoliatus.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1997, Bioscience, biotechnology, and biochemistry.

Structure of carquinostatin a, a new neuronal cell protecting substance produced by Streptomyces exfoliatus

K. Shin‐ya, Masahiro Tanaka, Y. Hayakawa, 1993 .

Arugomycin, a new anthracycline antibiotic. II. Structural elucidation.

M. Nakagawa, Y. Hayakawa, H. Seto, 1987, The Journal of antibiotics.

The structure of arugomycin, a new anthracycline antibiotic part I. structural elucidation of degradation products, AG1, AG2 and AG3.

M. Nakagawa, Y. Hayakawa, H. Seto, 1984 .

Studies on arugomycin, a new anthracycline antibiotic part II. structural elucidation of arugomycin

M. Nakagawa, Y. Hayakawa, H. Seto, 1984 .

Prodigiosin R2, a new prodigiosin from the roseophilin producer Streptomyces griseoviridis 2464-S5

Y. Hayakawa, T. Matsuda, Shoko Kimata, 2018, The Journal of Antibiotics.

Novel antibiotics pyrisulfoxin A and B produced by Streptomyces californicus.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1999, The Journal of antibiotics.

Insect cytokine, growth‐blocking peptide, is a primary regulator of melanin‐synthesis enzymes in armyworm larval cuticle

Y. Hayakawa, Yosuke Ninomiya, 2007, The FEBS journal.

Lydicamycin, a new antibiotic of a novel skeletal type. II. Physico-chemical properties and structure elucidation.

N. Morisaki, Y. Hayakawa, H. Seto, 1991, The Journal of antibiotics.

Induction and development of winter larval diapause in a drosophilid fly, Chymomyza costata.

V. Košťál, Y. Hayakawa, K. Shimada, 2000, Journal of insect physiology.

Microbial conversion of anthracyclinones to carminomycins by a blocked mutant of Actinomadura roseoviolacea.

M. Nakagawa, Y. Hayakawa, H. Seto, 1989, The Journal of antibiotics.

4-O-(beta-D-Glucopyranosyl)-epsilon-rhodomycinone, a new microbial transformation product of rhodomycinone.

M. Nakagawa, Y. Hayakawa, H. Seto, 1985, The Journal of antibiotics.

New ansamycin antibiotics, diastovaricins I and II.

Y. Hayakawa, M. Hotta, H. Seto, 1986, The Journal of antibiotics.

Isolation and structural elucidation of an antioxidative agent, naphterpin.

K. Shin‐ya, J. Clardy, Y. Hayakawa, 1990, The Journal of antibiotics.

A Novel Peptide Mediates Aggregation and Migration of Hemocytes from an Insect

M. Strand, T. Aizawa, M. Demura, 2009, Current Biology.

Venom components of Asobara japonica impair cellular immune responses of host Drosophila melanogaster.

H. Matsumoto, Y. Hayakawa, M. Kimura, 2013, Archives of insect biochemistry and physiology.

Mechanisms of black and white stripe pattern formation in the cuticles of insect larvae.

Y. Hayakawa, Kohjiro Tanaka, Yosuke Ninomiya, 2006, Journal of insect physiology.

Isolation and characterization of a dopa decarboxylase cDNA and the induction of its expression by an insect cytokine, growth-blocking peptide in Pseudaletia separata.

H. Matsumoto, S. Tsuzuki, Y. Hayakawa, 2003, Insect biochemistry and molecular biology.

Developmental changes in dopamine levels in larvae of the fly Chymomyza costata: comparison between wild-type and mutant-nondiapause strains.

V. Košťál, Y. Hayakawa, K. Shimada, 1998, Journal of insect physiology.

Role of dopamine at the onset of pupal diapause in the cabbage armyworm Mamestra brassicae

Y. Hayakawa, H. Noguchi, 1997, FEBS letters.

Mechanism of parasitism-induced elevation of dopamine levels in host insect larvae

Y. Hayakawa, H. Noguchi, 1996 .

Isolation and structure of a new phenoxazine antibiotic, exfoliazone, produced by Streptomyces exfoliatus.

Y. Hayakawa, H. Seto, K. Furihata, 1990, The Journal of antibiotics.

Taurine inhibits octopamine-stimulated cAMP production in cockroach haemocytes.

Y. Hayakawa, R. Downer, R. Bodnaryk, 1987, Biochimica et Biophysica Acta.

Cellular immunosuppressive protein in the plasma of parasitized insect larvae.

Y. Hayakawa, 1994, The Journal of biological chemistry.

N-terminal Residues of Plasmatocyte-spreading Peptide Possess Specific Determinants Required for Biological Activity*

B. Volkman, M. Strand, Y. Hayakawa, 2001, The Journal of Biological Chemistry.

Insect cytokine growth-blocking peptide (GBP) regulates insect development

Y. Hayakawa, 2006 .

Distribution of growth-blocking peptide in the insect central nervous tissue

A. Mizoguchi, A. Ohnishi, Y. Hayakawa, 2000, Cell and Tissue Research.

Telomestatin, a Novel Telomerase Inhibitor from Streptomyces annulatus.

Y. Hayakawa, K. Wierzba, Yuji Yamada, 2001 .

Molecular cloning of silkworm paralytic peptide and its developmental regulation.

Y. Nakahara, Y. Kanamori, M. Kiuchi, 2001, Biochemical and biophysical research communications.

Growth-blocking peptide titer during larval development of parasitized and cold-stressed armyworm.

A. Ohnishi, Y. Hayakawa, S. Sekiguchi, 1995, Insect biochemistry and molecular biology.

The Gly-Gly Linker Region of the Insect Cytokine Growth-blocking Peptide Is Essential for Activity*

M. Strand, T. Aizawa, M. Demura, 2004, Journal of Biological Chemistry.

Solution structure of paralytic peptide of silkworm, Bombyx mori

M. Kiuchi, M. Kamimura, T. Aizawa, 2002, Peptides.

Structure of the Insect Cytokine Peptide Plasmatocyte-spreading Peptide 1 from Pseudoplusia includens *

J. Markley, B. Volkman, M. Strand, 1999, The Journal of Biological Chemistry.

Bacteria Endosymbiont, Wolbachia, Promotes Parasitism of Parasitoid Wasp Asobara japonica

H. Matsumoto, Y. Hayakawa, Makiko Hirata, 2015, PloS one.

Immunoevasive protein (IEP)-containing surface layer covering polydnavirus particles is essential for viral infection.

H. Matsumoto, Masasuke Ryuda, Y. Hayakawa, 2014, Journal of invertebrate pathology.

Drosophila growth-blocking peptide-like factor mediates acute immune reactions during infectious and non-infectious stress

H. Matsumoto, S. Tsuzuki, A. Ohnishi, 2012, Scientific Reports.

Adaptor protein is essential for insect cytokine signaling in hemocytes

H. Matsumoto, A. Ohnishi, Y. Oda, 2010, Proceedings of the National Academy of Sciences.

Insect cytokine growth‐blocking peptide signaling cascades regulate two separate groups of target genes

S. Tsuzuki, Y. Oda, Y. Hayakawa, 2008, The FEBS journal.

Detailed characterization of polydnavirus immunoevasive proteins in an endoparasitoid wasp.

H. Matsumoto, Y. Hayakawa, Kohjiro Tanaka, 2002, European journal of biochemistry.

Stress-derived reactive oxygen species enable hemocytes to release activator of growth blocking peptide (GBP) processing enzyme.

H. Matsumoto, Y. Hayakawa, M. Ochiai, 2021, Journal of insect physiology.

Inhibition of diacylglycerol uptake from the fat body by a monoclonal antibody against apolipophorin II in Locusta migratoria

Y. Hayakawa, T. Hiraoka, 1990 .

Immunocytochemical localization of trehalase inhibitor in some insect species

Y. Hayakawa, R. Downer, T. Hiraoka, 1995, Cell and Tissue Research.

Characteristics of 45Ca2+ release induced by quinolidomicin A1, a 60-membered macrolide from skeletal muscle sarcoplasmic reticulum.

Y. Ohizumi, Y. Hayakawa, H. Seto, 1996, Biochimica et biophysica acta.

Absolute configuration of a novel glutamate receptor antagonist kaitocephalin

K. Shin‐ya, Y. Hayakawa, H. Seto, 2001 .

Relative and absolute configuration of versipelostatin, a down-regulator of molecular chaperone GRP78 expression.

K. Shin‐ya, Y. Hayakawa, K. Furihata, 2007, Organic Letters.

Absolute Configuration of a Novel Glutamate Receptor Antagonist Kaitocephalin.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2001 .

Akrobomycin, a new anthracycline antibiotic.

Y. Hayakawa, N. Ōtake, K. Imamura, 1984, Journal of antibiotics (Tokyo. 1968).

Insect fat body phosphorylase kinase is Ca2+-independent and acts even at 0°C

Y. Hayakawa, H. Chino, 1983 .

Cororubicin, a new anthracycline antibiotic generating active oxygen in tumor cells.

Y. Hayakawa, K. Ishigami, H. Seto, 1994, The Journal of antibiotics.

Biosynthetic Studies of Versipelostatin, a Novel 17‐Membered α‐Tetronic Acid Involved Macrocyclic Compound Isolated from Streptomyces versipellis.

K. Shin‐ya, Y. Hayakawa, T. Kuzuyama, 2003 .

Dunaimycin C3, a new GRP78 downregulator from Streptomyces sp. RAN389

K. Shin‐ya, Y. Hayakawa, Tomohiro Yoshida, 2020, The Journal of Antibiotics.

Arugomycin, a new anthracycline antibiotic.

M. Nakagawa, Y. Hayakawa, H. Seto, 1983, The Journal of antibiotics.

Structure-antitumor activity relationship of semi-synthetic spicamycin analogues.

T. Tsuruo, Y. Hayakawa, H. Seto, 1993, The Journal of antibiotics.

Biverlactones A–D, new circumventors of arbekacin resistance in MRSA, produced by Penicillium sp. FKI-4429

S. Ōmura, Y. Hayakawa, H. Hanaki, 2011 .

Aogacillins A and B produced by Simplicillium sp. FKI-5985: new circumventors of arbekacin resistance in MRSA.

G. A. Petersson, S. Ōmura, Y. Hayakawa, 2013, Organic letters.

Studies on new antitumor antibiotics, leptofuranins A, B, C and D II. Physiocochemical properties and structure elucidation.

Y. Hayakawa, H. Seto, K. Sohda, 1996, The Journal of antibiotics.

New antitumor antibiotics, anguinomycins A and B.

Y. Hayakawa, N. Komeshima, K. Adachi, 1987, The Journal of antibiotics.

Studies on the differentiation inducers of myeloid leukemic cells. Part VI. Spicamycin, a new differentiation inducer of mouse myeloid leukemia cells (M1) and human promyelocytic leukemia cells (HL-60).

M. Nakagawa, Y. Hayakawa, H. Seto, 1985 .

Studies on the differentiation inducers of myeloid leukemic cells. III. Spicamycin, a new inducer of differentiation of HL-60 human promyelocytic leukemia cells.

M. Nakagawa, Y. Hayakawa, H. Seto, 1983, The Journal of antibiotics.

Flaviogeranin, a new neuroprotective compound from Streptomyces sp.

K. Shin‐ya, M. Takagi, Y. Hayakawa, 2010, The Journal of Antibiotics.

Identification of a Novel Gene, Anorexia, Regulating Feeding Activity via Insulin Signaling in Drosophila melanogaster

T. Tanimura, H. Matsumoto, Masasuke Ryuda, 2011, The Journal of Biological Chemistry.

Lavanducyanin, a new antitumor substance produced by Streptomyces sp.

Y. Hayakawa, H. Seto, K. Furihata, 1989, The Journal of antibiotics.

The Drosophila cytokine, GBP: A model that illuminates the yin-yang of inflammation and longevity in humans?

Y. Hayakawa, S. Shears, 2018, Cytokine.

Switching between humoral and cellular immune responses in Drosophila is guided by the cytokine GBP

H. Matsumoto, Masasuke Ryuda, S. Tsuzuki, 2014, Nature Communications.

Isolation and characterization of atramycin A and atramycin B, new isotetracenone type antitumor antibiotics.

Y. Hayakawa, H. Seto, K. Furihata, 1991, Journal of antibiotics (Tokyo. 1968).

Factors influencing cyclic AMP and diacylglycerol levels in fat body of Locusta migratoria

Y. Hayakawa, R. Downer, Zhiwei Wang, 1990 .

Functional analysis of hatomarubigin biosynthesis genes and production of a new hatomarubigin using a heterologous expression system

Y. Hayakawa, T. Kawasaki, M. Izawa, 2013, The Journal of Antibiotics.

Studies on the isotetracenone antibiotics. I. Capoamycin, a new antitumor antibiotic.

Y. Hayakawa, H. Seto, N. Ōtake, 1985, The Journal of antibiotics.

Active Component of the Contraction Factor on Smooth Muscle Contraction of Gonad Wall in Sea Urchin(Reproductive Biology)

N. Takahashi, N. Sato, Y. Hayakawa, 1991 .

Isolation and Characterization of 2-Nitroimidazole Produced by Streptomyces Species as an Inhibitor of Both Carbonic Anhydrase and Shell Formation in the Barnacle Balanus amphitrite

H. Nagasawa, Y. Hayakawa, S. Sakuda, 2002, Marine Biotechnology.

Structure of Mescengricin, a Novel Neuronal Cell Protecting Substance Produced by Streptomyces griseoflavus.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1997 .

Changes of RNA virus infection rates and gut microbiota in young worker Apis mellifera (Hymenoptera: Apidae) of a chalkbrood-infected colony after a pollination task in a greenhouse

H. Matsumoto, Y. Hayakawa, Sachiyo Nomura, 2014, Applied Entomology and Zoology.

Oximidine III, a new antitumor antibiotic against transformed cells from Pseudomonas sp. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.

K. Shin‐ya, Y. Hayakawa, K. Nagai, 2003, The Journal of antibiotics.

Oximidine III, a New Antitumor Antibiotic Against Transformed Cells from Pseudomonas sp. Part 1. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity.

K. Shin‐ya, Y. Hayakawa, K. Nagai, 2004 .

Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress

J. Putney, Huanchen Wang, H. Matsumoto, 2017, Proceedings of the National Academy of Sciences.

Strains in the common cutworm, Spodoptera litura (Lepidoptera: Noctuidae) with differing host ranges

Y. Hayakawa, S. Tojo, Piyawan Phaophan, 2008 .

Repeated phenotypic selection for cuticular blackness of armyworm larvae decreased stress resistance.

H. Matsumoto, Y. Hayakawa, Takashi Matsumura, 2019, Journal of insect physiology.

Repeated phenotypic selection for cuticular blackness of armyworm larvae decreased stress resistance

H. Matsumoto, Y. Hayakawa, Takashi Matsumura, 2019, bioRxiv.

Temperature-dependent activation or inactivation of glycogen phosphorylase and synthase of fat body of the silkworm Philosamia cynthia: The possible mechanism of the temperature-dependent interconversion between glycogen and trehalose

Y. Hayakawa, H. Chino, 1982 .

A novel gene associated with intraspecific predation in Spodoptera litura larvae

Masasuke Ryuda, Y. Hayakawa, Hisayuki Nakayama, 2008 .

Roles of Aromatic Residues in the Structure and Biological Activity of the Small Cytokine, Growth-blocking Peptide (GBP)*

T. Aizawa, M. Tada, Yoshinori Shinohara, 2003, The Journal of Biological Chemistry.

Growth-blocking peptide: an insect biogenic peptide that prevents the onset of metamorphosis

Y. Hayakawa, 1995 .

A putative new juvenile peptide hormone in lepidopteran insects.

Y. Hayakawa, 1992, Biochemical and biophysical research communications.

A gene involved in the food preferences of larval Drosophila melanogaster.

T. Tanimura, Masasuke Ryuda, S. Tsuzuki, 2008, Journal of insect physiology.

Growth-blocking peptide expressed in the insect nervous system--cloning and functional characterization.

Y. Hayakawa, H. Noguchi, 1998, European journal of biochemistry.

Menoxymycins A and B antitumor antibiotics generating active oxygen in tumor cells.

K. Shin‐ya, Y. Hayakawa, K. Ishigami, 1994, Journal of antibiotics (Tokyo. 1968).

Menoxymycins A (I) and B (II), Antitumor Antibiotics Generating Active Oxygen in Tumor Cells.

K. Shin‐ya, Y. Hayakawa, K. Ishigami, 1995 .

Dopamine and serotonin in the larval CNS of a drosophilid fly, Chymomyza costata: are they involved in the regulation of diapause?

V. Košťál, Y. Hayakawa, K. Shimada, 1999, Archives of insect biochemistry and physiology.

The structure of a new isotetracenone antibiotic, capoamycin

Y. Hayakawa, H. Seto, N. Ōtake, 1985 .

Biosynthetic studies of naphterpin, a terpenoid metabolite of streptomyces

K. Shin‐ya, Y. Hayakawa, H. Seto, 1990 .

Benthocyanins B and C, New Free Radical Scavengers from Streptomyces prunicolor

K. Shin‐ya, Y. Hayakawa, H. Seto, 1993 .

A prodigiosin from the roseophilin producer Streptomyces griseoviridis.

Y. Hayakawa, T. Kawasaki, Fumie Sakurai, 2008, Journal of natural products.

Enhanced expression of genes in the brains of larvae of Mamestra brassicae (Lepidoptera: Noctuidae) exposed to short daylength or fed Dopa

S. Tsuzuki, Y. Hayakawa, M. Uryu, 2003 .

Trichostatin D, a new inducer of phenotypic reversion in transformed cells.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2000, The Journal of antibiotics.

Structure and activity of insect cytokine GBP which stimulates the EGF receptor.

T. Aizawa, K. Kawano, K. Nitta, 2002, Molecules and cells.

Quinomycins H1 and H2, new cytotoxic antibiotics from Streptomyces sp. RAL404

Y. Hayakawa, Risa Sone, Haruna Aoki, 2018, The Journal of Antibiotics.

Ammocidins B, C and D, new cytotoxic 20-membered macrolides from Saccharothrix sp. AJ9571

I. Kozone, K. Shin‐ya, M. Takagi, 2009, The Journal of Antibiotics.

Ammocidin, a new apoptosis inducer in Ras-dependent cells from Saccharothrix sp. I. Production, isolation and biological activity.

K. Shin‐ya, A. Miyajima, Y. Hayakawa, 2001, The Journal of antibiotics.

Ammocidins B, C and D, New Cytotoxic 20-Membered Macrolides from Saccharothrix sp. AJ9571.

I. Kozone, K. Shin‐ya, M. Takagi, 2009 .

Ammocidin, a new apoptosis inducer in ras-dependent cells from Saccharothrix sp. II. Physico-chemical properties and structure elucidation.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2001, The Journal of antibiotics.

Ammocidin, a New Apoptosis Inducer in Ras‐Dependent Cells from Saccharothrix sp. Part 1. Production, Isolation and Biological Activity.

K. Shin‐ya, A. Miyajima, Y. Hayakawa, 2002 .

Ammocidin, a New Apoptosis Inducer in Ras-Dependent Cells from Saccharothrix sp. Part 2. Physico-chemical Properties and Structure Elucidation.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2002 .

Turmeronol A and Turmeronol B, New Inhibitors of Soybean Lipoxygenase

Y. Hayakawa, H. Seto, K. Furihata, 1990 .

Structures of New Cytotoxic Antibiotics, Piericidins C7 and C8

Y. Hayakawa, Y. Matsuo, Y. Shizuri, 2007, The Journal of Antibiotics.

Structures of New Cytotoxic Antibiotics, Piericidins C7 and C8.

Y. Hayakawa, Y. Matsuo, Y. Shizuri, 2007 .

Bacillus subtilis ypgA Gene Is fni, a Nonessential Gene Encoding Type 2 Isopentenyl Diphosphate Isomerase

M. Takagi, Y. Hayakawa, T. Kuzuyama, 2004, Bioscience, biotechnology, and biochemistry.

Identification of essential biosynthetic genes and a true biosynthetic product for thioviridamide.

Y. Hayakawa, M. Izawa, Haruna Aoki, 2017, The Journal of general and applied microbiology.

Cloning and Heterologous Expression of the Thioviridamide Biosynthesis Gene Cluster from Streptomyces olivoviridis

Y. Hayakawa, T. Kawasaki, M. Izawa, 2013, Applied and Environmental Microbiology.

Mevashuntin, a novel metabolite produced by inhibition of the mevalonate pathway in Streptomyces prunicolor

K. Shin‐ya, Y. Hayakawa, H. Seto, 2005 .

Prodigiosin biosynthesis gene cluster in the roseophilin producer Streptomyces griseoviridis

Y. Hayakawa, T. Kawasaki, Fumie Sakurai, 2009, The Journal of Antibiotics.

Temperature-dependent interconversion between glycogen and trehalose in diapausing pupae of Philosamia cynthia ricini and pryeri

Y. Hayakawa, H. Chino, 1981 .

Oximidine III, a New Antitumor Antibiotic Against Transformed Cells from Pseudomonas sp. Part 2. Structure Elucidation.

K. Shin‐ya, Y. Hayakawa, K. Furihata, 2004 .

Growth blocking peptide

Y. Hayakawa, 2021, Handbook of Hormones.

Functional Multiplicity of an Insect Cytokine Family Assists Defense Against Environmental Stress

Y. Hayakawa, S. Shears, 2019, Front. Physiol..

Identification of a cytokine combination that protects insects from stress.

H. Matsumoto, Y. Hayakawa, Takashi Matsumura, 2018, Insect biochemistry and molecular biology.

Heat stress hardening of oriental armyworms is induced by a transient elevation of reactive oxygen species during sublethal stress.

H. Matsumoto, Y. Hayakawa, Takashi Matsumura, 2017, Archives of insect biochemistry and physiology.

Gain of long tonic immobility behavioral trait causes the red flour beetle to reduce anti-stress capacity.

H. Matsumoto, Masasuke Ryuda, T. Miyatake, 2014, Journal of insect physiology.

Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1.

Huanchen Wang, Y. Hayakawa, Shilan Wu, 2012, The Biochemical journal.

Enhanced expression of stress-responsive cytokine-like gene retards insect larval growth.

H. Matsumoto, S. Tsuzuki, Y. Hayakawa, 2012, Insect biochemistry and molecular biology.

Solution Structure of an Insect Growth Factor, Growth-blocking Peptide*

T. Aizawa, K. Kawano, K. Hikichi, 1999, The Journal of Biological Chemistry.

Elevation of dopamine levels in parasitized insect larvae

Y. Hayakawa, R. Downer, H. Noguchi, 1995 .

Effect of taurine on excitation-induced changes in brain and hemolymph octopamine levels in Periplaneta americana

Y. Hayakawa, R. Downer, R. Bodnaryk, 1987 .

Growth-blocking peptide or polydnavirus effects on the last instar larvae of some insect species

Y. Hayakawa, Y. Yasuhara, 1993 .

Purification and characterization of trehalase inhibitor from hemolymph of the American cockroach, Periplaneta americana.

Y. Hayakawa, M. Yaguchi, R. Downer, 1989, The Journal of biological chemistry.

C-terminal Elongation of Growth-blocking Peptide Enhances Its Biological Activity and Micelle Binding Affinity*

T. Aizawa, M. Demura, M. Mizuguchi, 2009, The Journal of Biological Chemistry.

Identification of a Gene, Desiccate, Contributing to Desiccation Resistance in Drosophila melanogaster*

M. Shimoda, H. Matsumoto, Masasuke Ryuda, 2010, The Journal of Biological Chemistry.

Cells expressing Desiccate are essential for morphogenesis of labial sensilla in Drosophila melanogaster adults

H. Matsumoto, S. Tsuzuki, H. Kanuka, 2011 .

Cause of mortality in insects under severe stress.

H. Matsumoto, Y. Hayakawa, Kohjiro Tanaka, 2003, European journal of biochemistry.

Structure of a novel 60-membered macrolide, quinolidomicin A1

K. Shin‐ya, Y. Hayakawa, H. Seto, 1993 .

A neuronal cell protecting substance, 4-demethoxymichigazone, produced by Streptomyces halstedii.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1996, The Journal of antibiotics.

Novel neuronal cell protecting substances, aestivophoenins A and B, produced by Streptomyces purpeofuscus.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1995, The Journal of antibiotics.

Structure of Benthophoenin, a New Free Radical Scavenger Produced by Streptomyces prunicolor

K. Shin‐ya, Y. Hayakawa, H. Seto, 1993 .

Cytovaricin B, a New Inhibitor of JAK‐STAT Signal Transduction Produced by Streptomyces torulosus.

K. Shin‐ya, A. Miyajima, H. Wakao, 1997 .

Inclusion of a beta-aspartyl peptide bond causes the loss of inherent physiological activities.

Y. Hayakawa, 1994, Journal of biochemistry.

Inhibition of lipid transport in insects by a factor secreted by the parasite, Blepharipa sericariae

Y. Hayakawa, 1986 .

Analysis in the course of polydnavirus replication in ovarian calyx cells of the parasitoid wasp, Cotesia kariyai (Hymenoptera: Braconidae)

H. Matsumoto, Y. Hayakawa, Kohjiro Tanaka, 2002 .

Insect fat body phosphorylase kinase is Ca2+-independent and acts even at 0 degrees C.

Y. Hayakawa, H. Chino, 1983, Biochimica et Biophysica Acta.

A novel neuronal cell protecting substance, halxazone, produced by Streptomyces halstedii.

K. Shin‐ya, Y. Hayakawa, K. Furihata, 2002, The Journal of antibiotics.

Inhibition of lipid transport in insects by a parasitic factor

Y. Hayakawa, 1987 .

Structure of Thioviridamide, a Novel Apoptosis Inducer from Streptomyces olivoviridis.

K. Shin‐ya, Y. Hayakawa, K. Furihata, 2006 .

N-terminal mutational analysis of the interaction between growth-blocking peptide (GBP) and receptor of insect immune cells.

T. Aizawa, M. Demura, M. Tada, 2006, Protein Peptide Letters.

Structure and Activity of the Insect Cytokine Growth-blocking Peptide ESSENTIAL REGIONS FOR MITOGENIC AND HEMOCYTE-STIMULATING ACTIVITIES ARE SEPARATE*

M. Strand, T. Aizawa, M. Demura, 2001 .

A Novel Substance with TGF-β Like Activity, Diheteropeptin, Produced by a Fungus, Diheterospora sp.

K. Shin‐ya, Y. Hayakawa, H. Seto, 1998 .

New Ravidomycin Analogues, FE35A and FE35B, Apoptosis Inducers Produced by Streptomyces rochei

K. Shin‐ya, Y. Hayakawa, H. Seto, 1999 .

13-Deoxo-13-iminodutomycin, a new neuroprotective compound from Streptomyces sp. RAP78

Y. Hayakawa, Shoko Kimata, Yuta Ibusuki, 2021, The Journal of Antibiotics.

Pyroxazone, a new neuroprotective compound from Streptomyces sp. RAN54

Y. Hayakawa, Shoko Kimata, Yuta Ibusuki, 2018, The Journal of Antibiotics.

A new anthracycline antibiotic N-formyl-13-dihydrocarminomycin.

M. Nakagawa, Y. Hayakawa, H. Seto, 1983, The Journal of antibiotics.

Spicamycin, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml) and Human Promyelocytic Leukemia Cells (HL-60)

M. Nakagawa, Y. Hayakawa, H. Seto, 1985 .

Phosphofructokinase as a possible key enzyme regulating glycerol or trehalose accumulation in diapausing insects

Y. Hayakawa, H. Chino, 1982 .

Synthesis of the Proposed Structure (Ia) and Revision of Stereochemistry of Kaitocephalin (Ib).

K. Shin‐ya, Y. Hayakawa, T. Kitahara, 2002 .

Diheteropeptin, a New Substance with TGF-β-Like Activity, Produced by a Fungus, Diheterospora chlamydosporia. Part 1. Production, Isolation and Biological Activities.

K. Shin‐ya, Y. Hayakawa, Minoru Yoshida, 2001 .

Diheteropeptin, a novel substance with TGF-beta-like activity, produced by a fungus, Diheterospora chlamydosporia. II. Physico-chemical properties and structure elucidation.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2000, The Journal of antibiotics.

Diheteropeptin, a Novel Substance with TGF‐β‐Like Activity, Produced by a Fungus, Diheterospora chlamydosporia. Part 2. Physicochemical Properties and Structure Elucidation.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2001 .

ANALYSIS OF FOOD PREFERENCE OF DROSOPHILA MELANOGASTER LARVAE AT THE GENE LEVEL(Physiology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)

Masasuke Ryuda, Y. Hayakawa, 2005 .

Efrapeptin J, a New Down‐Regulator of the Molecular Chaperone GRP78 from a Marine Tolypocladium sp.

K. Shin‐ya, Y. Hayakawa, Y. Shizuri, 2008 .

Byssochlamysol, a New Antitumor Steroid Against IGF-1-Dependent Cells from Byssochlamys nivea. Part 1. Taxonomy, Fermentation, Isolation and Biological Activity.

K. Shin‐ya, Y. Hayakawa, Toshiya Mori, 2003 .

Byssochlamysol, a new antitumor steroid against IGF-1-dependent cells from Byssochlamys nivea. II. Physico-chemical properties and structure elucidation.

K. Shin‐ya, Y. Hayakawa, Toshiya Mori, 2003, The Journal of antibiotics.

Structure of tyroscherin, an antitumor antibiotic against IGF-1-dependent cells from Pseudallescheria sp.

K. Shin‐ya, T. Yamashita, Y. Hayakawa, 2004, The Journal of antibiotics.

Burkholone, A New Cytotoxic Antibiotic against IGF-I Dependent Cells from Burkholderia sp.

K. Shin‐ya, T. Yamashita, Y. Hayakawa, 2007, The Journal of Antibiotics.

Rasfonin, a new apoptosis inducer in ras-dependent cells from Talaromyces sp.

K. Shin‐ya, A. Miyajima, Y. Hayakawa, 2000, The Journal of antibiotics.

Selective cytotoxicity and stereochemistry of aspochalasin D.

K. Shin‐ya, A. Miyajima, Y. Hayakawa, 2001, The Journal of antibiotics.

Rasfonin, a New Apoptosis Inducer in ras‐Dependent Cells from Talaromyces sp.

K. Shin‐ya, A. Miyajima, Y. Hayakawa, 2001 .

Isolation of new anthracycline antibiotics, A447 C and D.

M. Nakagawa, Y. Hayakawa, H. Seto, 1987, The Journal of antibiotics.

Structure of aspochalasin H, a new member of the aspochalasin family.

K. Shin‐ya, Y. Hayakawa, H. Seto, 2002, The Journal of antibiotics.

Cloning and Characterization of a Gene Cluster for Hatomarubigin Biosynthesis in Streptomyces sp. Strain 2238-SVT4

Y. Hayakawa, T. Kawasaki, A. Maeda, 2010, Applied and Environmental Microbiology.

Cloning and Characterization of a Gene Cluster for Hatomarubigin Biosynthesis in Streptomyces sp . Strain 2238-SVT 4

Y. Hayakawa, T. Kawasaki, A. Maeda, 2010 .

Hatomarubigin E, a biosynthetic intermediate of hatomarubigins C and a substrate of HrbU O-methyltransferase

Y. Hayakawa, T. Kawasaki, A. Maeda, 2010, The Journal of Antibiotics.

Studies on the isotetracenone antibiotics. IV. Hatomarubigins A, B, C and D, new isotetracenone antibiotics effective against multidrug-resistant tumor cells.

Y. Hayakawa, H. Seto, K. Furihata, 1991, The Journal of antibiotics.

Studies on the isotetracenone antibiotics. III. A new isotetracenone antibiotic, grincamycin.

Y. Hayakawa, H. Seto, N. Ōtake, 1987, The Journal of antibiotics.

Peptide mimics of epidermal growth factor (EGF) with antagonistic activity.

T. Aizawa, Y. Mori, H. Shinoda, 2005, Journal of biotechnology.

Gymnasterol, a new antitumor steroid against IGF-dependent cells from Gymnascella dankaliensis

K. Shin‐ya, Y. Hayakawa, Toshiya Mori, 2003 .

Antitumor activity of SPM VIII, a derivative of the nucleoside antibiotic spicamycin, against human tumor xenografts.

T. Tsuruo, Y. Hayakawa, H. Seto, 1994, The Journal of antibiotics.

Identification of a prodigiosin cyclization gene in the roseophilin producer and production of a new cyclized prodigiosin in a heterologous host

Y. Hayakawa, T. Kawasaki, M. Izawa, 2016, The Journal of Antibiotics.

Prodigiosin R2, a new prodigiosin from the roseophilin producer Streptomyces griseoviridis 2464-S5

Y. Hayakawa, T. Matsuda, Shoko Kimata, 2018, The Journal of Antibiotics.

Discovery of a novel antitumor benzolactone enamide class that selectively inhibits mammalian vacuolar-type (H+)-atpases.

J. Kim, M. Boyd, E. J. Bowman, 2001, The Journal of pharmacology and experimental therapeutics.

STRUCTURE OF LYDICAMYCIN, A NEW ANTIBIOTIC OF A NOVEL SKELETAL TYPE

N. Morisaki, Y. Hayakawa, H. Seto, 1991 .

Adaptor protein is essential for insect cytokine signaling in hemocytes

H. Matsumoto, A. Ohnishi, Y. Oda, 2010, Proceedings of the National Academy of Sciences.

Studies on the differentiation inducers of myeloid leukemic cells. Part IV. Latosillan, a new differentiation inducer of mouse myeloid leukemia cells (M1): Taxonomy, fermentation, isolation, physicochemical properties and biological properties.

Y. Hayakawa, H. Seto, N. Ōtake, 1985 .

Contributory presentations/posters

Diederichs, Bosco K. Ho, Hironori K. Nakamura, 1999, Journal of Biosciences.

Identification of a Novel Gene, Anorexia, Regulating Feeding Activity via Insulin Signaling in Drosophila melanogaster

T. Tanimura, H. Matsumoto, Masasuke Ryuda, 2011, The Journal of Biological Chemistry.