D. Freymann

发表

The signal recognition particle.

R. Stroud, P. Walter, R. Keenan, 2001, Annual review of biochemistry.

2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei.

D. Wiley, M. Carrington, M. Turner, 1990, Journal of molecular biology.

The conformation of bound GMPPNP suggests a mechanism for gating the active site of the SRP GTPase.

D. Freymann, S. Padmanabhan, 2001, Structure.

Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase.

P. Focia, S. Chakravarthy, E. Landahl, 2020, Journal of structural biology.

Structural assembly of the human Miro1/2 GTPases based on the crystal structure of the N-terminal GTPase domain

P. Focia, S. Chakravarthy, E. Landahl, 2019, bioRxiv.

NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP).

P. Walter, T. James, R. Keenan, 1996, RNA.

Novel protein and Mg2+ configurations in the Mg2+GDP complex of the SRP GTPase ffh

Hena Alam, P. Focia, D. Freymann, 2003, Proteins.

The crystal structure of thymidylate synthase from Pneumocystis carinii reveals a fungal insert important for drug design.

R. Stroud, A. Anderson, K. M. Perry, 2000, Journal of molecular biology.

Structure of a tetrameric galectin from Cinachyrella sp. (ball sponge).

R. Sakai, P. Focia, D. Freymann, 2012, Acta crystallographica. Section D, Biological crystallography.

Two variant surface glycoproteins of Trypanosoma Brucei of different sequence classes have similar 6 Å resolution X-ray structures

D. Wiley, M. Turner, D. Freymann, 1987, Nature.

Ion-channel-forming colicins.

R. Stroud, M. Wiener, D. Freymann, 1998, Current opinion in structural biology.

Crystal Structure of the Signal Sequence Binding Subunit of the Signal Recognition Particle

R. Stroud, P. Walter, R. Keenan, 1998, Cell.

Crystal structure of colicin Ia

R. Stroud, M. Wiener, D. Freymann, 1997, Nature.

Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction site.

J. Coon, P. Focia, D. Freymann, 2006, Journal of molecular biology.

Heterodimeric GTPase Core of the SRP Targeting Complex

P. Focia, D. Freymann, J. Seidler, 2004, Science.

Conformational change of the N-domain on formation of the complex between the GTPase domains of Thermus aquaticus Ffh and FtsY.

D. Freymann, Irina V Shepotinovskaya, 2002, Biochimica et biophysica acta.

Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh.

Peter Walter, Peter Kuhn, Robert M Stroud, 2002, Journal of Molecular Biology.

Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog.

P. Walter, D. Zopf, D. Freymann, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Structural insights into Parkin substrate lysine targeting from minimal Miro substrates

P. Focia, D. Freymann, S. Rice, 2016, Scientific Reports.

Protein, DNA, and virus crystallography with a focused imaging proportional counter.

P Metcalf, S. Harrison, D. Wiley, 1986, Science.

Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor.

P. Peluso, D. Herschlag, P. Walter, 2000, Science.

6 Å-Resolution X-ray structure of a variable surface glycoprotein from Trypanosoma brucei

D. Wiley, M. Turner, D. Freymann, 1984, Nature.

Analysis of protein hydration in ultrahigh-resolution structures of the SRP GTPase Ffh.

D. Freymann, U. Ramirez, 2006, Acta crystallographica. Section D, Biological crystallography.

Mapping the functional anatomy of Orai1 transmembrane domains for CRAC channel gating

R. Pomès, D. Freymann, M. Prakriya, 2018, Proceedings of the National Academy of Sciences.

Structure of the GMPPNP-stabilized NG domain complex of the SRP GTPases Ffh and FtsY.

D. Freymann, J. Gawronski-Salerno, 2006, Journal of structural biology.

Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi.

P. Focia, S. Craig, A. Eakin, 2000, Chemistry & biology.

Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity

S. N. Murthy, L. Lorand, R. Graham, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP

R. Stroud, P. Walter, R. Keenan, 1999, Nature Structural Biology.

X‐ray structure of the T. Aquaticus Ftsy:GDP complex suggests functional roles for the C‐terminal helix of the SRP GTPases

P. Focia, D. Freymann, J. Coon V, 2006, Proteins.

Crystallization of the GMPPCP complex of the NG domains of Thermus aquaticus Ffh and FtsY.

P. Focia, D. Freymann, Irina V Shepotinovskaya, 2003, Acta crystallographica. Section D, Biological crystallography.

Structure of the conserved GTPase domain of the signal recognition particle

R. Stroud, P. Walter, R. Keenan, 1997, Nature.

Structure of the phylogenetically most conserved domain of SRP RNA.

P. Walter, T. James, R. Keenan, 1999, RNA.

Nucleotide-binding flexibility in ultrahigh-resolution structures of the SRP GTPase Ffh

P. Focia, D. Freymann, U. Ramirez, 2008, Acta crystallographica. Section D, Biological crystallography.

Purification of RanGDP, RanGTP, and RanGMPPNP by ion exchange chromatography.

D. Freymann, R. Paul, N. Yaseen, 2004, Analytical biochemistry.

A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation

R. Sakai, P. Focia, M. Hirayama, 2022, Nature Communications.

Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety

R. Sakai, Yoshikazu Tanaka, P. Focia, 2021, bioRxiv.

Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor.

P. Peluso, D. Herschlag, S. Nock, 2000, Science.

Structural coupling of the EF hand and C‐terminal GTPase domains in the mitochondrial protein Miro

P. Focia, S. Chakravarthy, E. Landahl, 2013, EMBO reports.

Computational Constraints on Syntactic Processing in a Nonhuman Primate

Peter Walter, Douglas M. Freymann, Robert J. Keenan, 2004 .