D. Sparrow

发表

Evolution of distinct EGF domains with specific functions

Lina L. Feng, I. Rigoutsos, L. Feng, 2005, Protein science : a publication of the Protein Society.

A Mechanism for Gene-Environment Interaction in the Etiology of Congenital Scoliosis

Ryoichiro Kageyama, Sally L. Dunwoodie, Kenro Kusumi, 2012, Cell.

Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.

E. Kremmer, S. Dunwoodie, D. Sparrow, 2011, Human molecular genetics.

Complex SUMO-1 Regulation of Cardiac Transcription Factor Nkx2-5

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2011, PloS one.

Regulation of the tinman homologues in Xenopus embryos.

D. Sparrow, T. Mohun, S. Evans, 2000, Developmental biology.

Two novel missense mutations in HAIRY-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis

D. Sillence, M. A. Wouters, S. Dunwoodie, 2010, European Journal of Human Genetics.

Better communication between experts is needed to solve the environmental origins of birth defects

D. Sparrow, 2021, BioEssays : news and reviews in molecular, cellular and developmental biology.

A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data

D. Humphreys, E. Giannoulatou, S. Dunwoodie, 2018, Circulation. Genomic and precision medicine.

Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling.

S. Grieve, N. Kurniawan, S. Dunwoodie, 2015, Kidney international.

The morphology of heart development in Xenopus laevis.

W. Weninger, D. Sparrow, T. Mohun, 2000, Developmental biology.

A simplified method of generating transgenic Xenopus.

D. Sparrow, B. Latinkić, T. Mohun, 2000, Nucleic acids research.

Subdivision of the cardiac Nkx2.5 expression domain into myogenic and nonmyogenic compartments.

M. Mercola, D. Sparrow, T. Mohun, 2000, Developmental biology.

Gene-environment interaction impacts on heart development and embryo survival

A. Moon, A. Baldini, S. Dunwoodie, 2019, Development.

Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype.

D. Sillence, S. Ellard, D. Fatkin, 2006, American journal of human genetics.

Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis.

Milena B. Furtado, D. Fatkin, S. Dunwoodie, 2011, Human molecular genetics.

Early steps in vertebrate cardiogenesis.

D. Sparrow, T. Mohun, 1997, Current opinion in genetics & development.

Placental insufficiency associated with loss of Cited1 causes renal medullary dysplasia.

S. Dunwoodie, M. D. de Caestecker, D. Sparrow, 2009, Journal of the American Society of Nephrology : JASN.

Functional genomics and gene-environment interaction highlight the complexity of Congenital Heart Disease caused by Notch pathway variants.

S. Grieve, E. Giannoulatou, S. Dunwoodie, 2019, Human molecular genetics.

Genetic and Environmental Interaction in Malformation of the Vertebral Column

S. Dunwoodie, D. Sparrow, 2015 .

Mutation of HES7 in a large extended family with spondylocostal dysostosis and dextrocardia with situs inversus

R. Kageyama, S. Ellard, S. Dunwoodie, 2013, American journal of medical genetics. Part A.

Mutated MESP2 causes spondylocostal dysostosis in humans.

D. Sillence, S. Ellard, M. A. Wouters, 2004, American journal of human genetics.

Transcriptional regulation of the cardiac-specific MLC2 gene during Xenopus embryonic development

D. Sparrow, T. Mohun, S. Kotecha, 2004, Development.

The MLC1v gene provides a transgenic marker of myocardium formation within developing chambers of the Xenopus heart

D. Sparrow, T. Mohun, P. Ataliotis, 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

Cited2 is required in trophoblasts for correct placental capillary patterning.

S. Dunwoodie, G. Leone, D. Sparrow, 2014, Developmental biology.

Distinct enhancers regulate skeletal and cardiac muscle-specific expression programs of the cardiac alpha-actin gene in Xenopus embryos.

D. Sparrow, T. Mohun, S. Kotecha, 2002, Developmental biology.

Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors.

D. Humphreys, P. Giampietro, S. Dunwoodie, 2022, Differentiation; research in biological diversity.

NAD Deficiency, Congenital Malformations, and Niacin Supplementation

James N. Hughes, D. Sillence, M. Brown, 2017, The New England journal of medicine.

The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition

T. Enver, M. D. de Bruijn, D. Sparrow, 2021, Cell reports.

The mouse notches up another success: understanding the causes of human vertebral malformation

S. Dunwoodie, D. Sparrow, G. Chapman, 2011, Mammalian Genome.

Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.

Kenro Kusumi, Sally L Dunwoodie, E. Rappaport, 2009, Developmental biology.

Disruption of the somitic molecular clock causes abnormal vertebral segmentation.

S. Dunwoodie, D. Sparrow, G. Chapman, 2007, Birth defects research. Part C, Embryo today : reviews.

Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.

R. Beddington, S. Dunwoodie, M. Clements, 2002, Development.

A loss-of-function mutation in the mouse delta-like3 (Dll3)

R. Beddington, S. Dunwoodie, M. Clements, 2002 .

Diverse requirements for Notch signalling in mammals.

D. Sillence, R. Beddington, J. Novotný, 2002, The International journal of developmental biology.

Thylacine 1 is expressed segmentally within the paraxial mesoderm of the Xenopus embryo and interacts with the Notch pathway.

D. Sparrow, T. Mohun, C. Kintner, 1998, Development.

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

E. Kremmer, S. Dunwoodie, D. Sparrow, 2007, The Journal of cell biology.

Old wares and new: five decades of investigation of somitogenesis in Xenopus laevis.

D. Sparrow, 2008, Advances in experimental medicine and biology.

Autosomal dominant spondylocostal dysostosis is caused by mutation in TBX6.

M. Brown, M. Marshall, B. Gardiner, 2013, Human molecular genetics.

Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis.

D. Fatkin, S. Dunwoodie, D. Sparrow, 2008, Human molecular genetics.

Maternal iron deficiency perturbs embryonic cardiovascular development in mice

Jacob T. Munro, E. Giannoulatou, V. Tybulewicz, 2021, Nature Communications.

Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects.

M. Brown, M. Marshall, B. Gardiner, 2015, Human molecular genetics.

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

G. Kay, N. Brockdorff, S. Dunwoodie, 2008, Nature Genetics.

MEF‐2 function is modified by a novel co‐repressor, MITR

E. Miska, T. Kouzarides, E. Langley, 1999, The EMBO journal.

Gestational stress induces the unfolded protein response, resulting in heart defects

S. Grieve, S. Dunwoodie, R. Graham, 2016, Mechanisms of Development.

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta.

S. Dunwoodie, D. Sparrow, K. Lopes Floro, 2006, Developmental biology.

Cited1 Is Required in Trophoblasts for Placental Development and for Embryo Growth and Survival

R. Beddington, S. Dunwoodie, M. Clements, 2004, Molecular and Cellular Biology.

The RSRF/MEF2 protein SL1 regulates cardiac muscle-specific transcription of a myosin light-chain gene in Xenopus embryos.

D. Sparrow, T. Mohun, M. Logan, 1994, Genes & development.

Heterozygous loss of WBP11 function causes multiple congenital defects in humans and mice.

D. Humphreys, P. Giampietro, E. Giannoulatou, 2020, Human molecular genetics.

Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2

M. Dasso, H. Saitoh, T. Nishimoto, 1998, Current Biology.

BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4.

Milena B. Furtado, Mauro W. Costa, S. Dunwoodie, 2008, Genes & development.

Xenopus laevis transgenesis by sperm nuclear injection

D. Sparrow, T. Mohun, Stuart J. Smith, 2006, Nature Protocols.

Gene-environment interaction demonstrates the vulnerability of the embryonic heart.

S. Grieve, S. Dunwoodie, R. Harvey, 2014, Developmental biology.

The Small Muscle-Specific Protein Csl Modifies Cell Shape and Promotes Myocyte Fusion in an Insulin-like Growth Factor 1–Dependent Manner

N. Copeland, N. Jenkins, L. Barnett, 2001, The Journal of cell biology.

Environmental Risk Factors for Congenital Heart Disease.

D. Sparrow, N. Ved, J. Kalisch-Smith, 2019, Cold Spring Harbor perspectives in biology.

Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo

F. Ashcroft, D. Sparrow, N. Ved, 2019, Laboratory animals.

The Transcriptional Activity of CITED1 Is Regulated by Phosphorylation in a Cell Cycle-dependent Manner*

S. Dunwoodie, G. Shi, M. D. de Caestecker, 2006, Journal of Biological Chemistry.

Sequence of a cDNA encoding chicken high-mobility-group protein-2.

D. Sparrow, J. Wells, 1992, Gene.

Maternal iron deficiency perturbs embryonic cardiovascular development

E. Giannoulatou, Jacob E. Munro, V. Tybulewicz, 2020, bioRxiv.

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

G. Douglas, H. Watkins, M. Gautel, 2023, Cells.

Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects

D. Sparrow, J. Vieira, P. Riley, 2022, Frontiers in Genetics.

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant

H. Watkins, B. Davies, E. Ehler, 2021, Basic Research in Cardiology.

Xenopus eHAND: a marker for the developing cardiovascular system of the embryo that is regulated by bone morphogenetic proteins

D. Sparrow, T. Mohun, S. Kotecha, 1998, Mechanisms of Development.

Kousseff syndrome: A causally heterogeneous disorder

S. Dunwoodie, D. Sparrow, E. Kirk, 2004, American journal of medical genetics. Part A.

Generation of conditional Cited2 null alleles

S. Dunwoodie, R. Harvey, D. Sparrow, 2006, Genesis.

MEF2 proteins, including MEF2A, are expressed in both muscle and non-muscle cells.

E. Dodou, R. Treisman, D. Sparrow, 1995, Nucleic acids research.

Autosomal dominant spondylocostal dysostosis in three generations of a Macedonian family: Negative mutation analysis of DLL3, MESP2, HES7, and LFNG

S. Ellard, Z. Gucev, V. Tasic, 2010, American journal of medical genetics. Part A.

Spondylocostal dysostosis in a pregnancy complicated by confined placental mosaicism for tetrasomy 9p

S. Dunwoodie, D. Amor, D. Sparrow, 2008, American journal of medical genetics. Part A.

Transcriptional regulation of the cardiac-specific MLC2 gene during Xenopus embryonic development

D. Sparrow, T. Mohun, S. Kotecha, 2004, Development.

Spondylocostal dysostosis in a pregnancy complicated by confined placental mosaicism for tetrasomy 9p

S. Dunwoodie, D. Amor, D. Sparrow, 2008, American journal of medical genetics. Part A.