J. Reichhart

发表

Tip of another iceberg: Drosophila serpins.

J. Reichhart, Jean-Marc Reichhart, 2005, Trends in cell biology.

Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation.

L. Troxler, J. Reichhart, F. Veillard, 2016, Biochimie.

E. Birney, P. Bork, S. Meister, 2002, Science.

A genome-wide analysis of immune responses in Drosophila

M. Belvin, C. Kopczynski, J. Hoffmann, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Innate immunity in higher insects.

J. Hoffmann, C. Hétru, J. Reichhart, 1996, Current opinion in immunology.

Involvement of the Cytokine MIF in the Snail Host Immune Response to the Parasite Schistosoma mansoni

C. Coustau, C. Dissous, D. Colinet, 2010, PLoS pathogens.

big bang gene modulates gut immune tolerance in Drosophila

Michael J. Hoffmann, J. Hoffmann, J. Reichhart, 2013, Proceedings of the National Academy of Sciences.

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia.

B. Lemaître, M. Capovilla, J. Hoffmann, 2000, Immunity.

Insect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides.

P. Lepage, A. van Dorsselaer, J. Hoffmann, 1989, Proceedings of the National Academy of Sciences of the United States of America.

A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens.

C. Sasakawa, H. Kiyono, Taira Kobayashi, 2011, Cell host & microbe.

Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila

M. Boutros, A. Orian, X. Nguyen, 2020, PLoS pathogens.

Detection of peptidoglycans by NOD proteins.

J. Reichhart, J. Royet, 2003, Trends in cell biology.

Cell Host & Microbe Tecpr 1 in Selective Autophagy formation in mammalian cells

C. Sasakawa, H. Kiyono, Taira Kobayashi, 2011 .

The LBP/BPI multigenic family in invertebrates: Evolutionary history and evidences of specialization in mollusks.

C. Coustau, J. Reichhart, E. Deleury, 2016, Developmental and comparative immunology.

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity.

R. Lanot, M. Meister, J. Hoffmann, 1994, European journal of biochemistry.

The multilayered innate immune defense of the gut

M. Ntwasa, J. Reichhart, Nicolas Matt, 2015, Biomedical journal.

The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

D. Gubb, M. Belvin, C. Rossé, 2002, Immunity.

Recognition and Rejection of Self in Plant Reproduction

Alan Aderem, S. Akira, C. Janeway, 2002 .

Cloning of the gene encoding the antibacterial peptide drosocin involved in Drosophila immunity. Expression studies during the immune response.

M. Meister, M. Lagueux, J. Reichhart, 1996, European journal of biochemistry.

Determination of the disulfide array of the first inducible antifungal peptide from insects: drosomycin from Drosophila melanogaster

P. Fehlbaum, M. Moniatte, A. van Dorsselaer, 1996, FEBS letters.

Critical evaluation of the role of the Toll‐like receptor 18‐Wheeler in the host defense of Drosophila

P. Bulet, J. Reichhart, P. Ligoxygakis, 2002, EMBO reports.

Drosophila immunity. A sequence homologous to mammalian interferon consensus response element enhances the activity of the diptericin promoter.

P. Georgel, E. Langley, J. Hoffmann, 1995, Nucleic acids research.

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements.

M. Meister, B. Lemaître, P. Georgel, 1993, Biochemical and biophysical research communications.

Serpins Flex Their Muscle

J. Whisstock, S. Bottomley, J. Huntington, 2010, The Journal of Biological Chemistry.

The humoral antibacterial response of Drosophila

J. Hoffmann, C. Hétru, J. Reichhart, 1993, FEBS letters.

Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family.

J. Hoffmann, P. Bulet, C. Hétru, 1991, The Journal of biological chemistry.

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF

R. Steward, B. Lemaître, J. Reichhart, 1999, The EMBO journal.

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.

D. Hultmark, C. Samakovlis, J. Hoffmann, 1990, The Journal of biological chemistry.

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

R. Steward, S. Govind, M. Meister, 1995, The EMBO journal.

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling.

J. Reichhart, P. Meier, N. Silverman, 2010, Molecular cell.

A serpin mutant links Toll activation to melanization in the host defence of Drosophila

M. Belvin, B. Duvic, J. Reichhart, 2002, The EMBO journal.

Toll-dependent and Toll-independent immune responses in Drosophila

J. Hoffmann, J. Imler, C. Hétru, 2004, Journal of endotoxin research.

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae.

D. Zachary, J. Reichhart, J. Dimarcq, 1990, The EMBO journal.

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter.

D. Zachary, M. Meister, J. Reichhart, 1992, The EMBO journal.

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila.

J. Hoffmann, C. Hétru, J. Reichhart, 2000, Immunity.

TLR5 takes aim at bacterial propeller

J. Reichhart, 2003, Nature Immunology.

Structure-Function Analysis of Grass Clip Serine Protease Involved in Drosophila Toll Pathway Activation*

A. Roussel, J. Reichhart, T. Jouenne, 2011, The Journal of Biological Chemistry.

Evolution and integration of innate immune systems from fruit flies to man: lessons and questions

J. Reichhart, Cosimo Martinelli, 2005, Journal of endotoxin research.

Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease

J. Hoffmann, J. Reichhart, Nadège Pelte, 2002, Science.

Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms.

B. Lemaître, J. Hoffmann, J. Reichhart, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity.

A. Orian, J. Reichhart, B. Koltun, 2017, The International journal of developmental biology.

Prophenoloxidase activation is not required for survival to microbial infections in Drosophila

J. Hoffmann, J. Reichhart, Nadège Pelte, 2006, EMBO reports.

Phagocytosis in Drosophila melanogaster Immune Response

J. Reichhart, I. Caldelari, V. Leclerc, 2009 .

Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila

C. Kocks, M. Rämet, M. Meister, 2005, Cell.

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

B. Lemaître, J. Hoffmann, J. Reichhart, 1996, Cell.

Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of the dipteran Phormia terranovae and complete amino-acid sequence of the predominant member, diptericin A.

J. Hoffmann, J. Reichhart, J. Dimarcq, 1988, European journal of biochemistry.

Drosophila innate immunity: an evolutionary perspective

J. Hoffmann, J. Reichhart, 2002, Nature Immunology.

The necrotic gene in Drosophila corresponds to one of a cluster of three serpin transcripts mapping at 43A1.2.

D. Gubb, E. Levashina, J. Reichhart, 2000, Genetics.

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila.

M. Ashburner, D. Gubb, E. Levashina, 1999, Science.

Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors

Dominique Ferrandon, M. Belvin, Chengshu Wang, 2006, Cell.

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

M. Meister, B. Lemaître, P. Georgel, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

T. Michel, J. Hoffmann, J. Reichhart, 2001, Nature.

Serpins Flex Their Muscle

James C Whisstock, Dion Kaiserman, Stephen P Bottomley, 2010, The Journal of Biological Chemistry.

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties.

E. Levashina, J. Hoffmann, P. Bulet, 1995, European journal of biochemistry.

Insect immunity. Isolation of cDNA clones corresponding to diptericin, an inducible antibacterial peptide from Phormia terranovae (Diptera). Transcriptional profiles during immunization.

M. Lagueux, J. Hoffmann, J. Reichhart, 1989, European journal of biochemistry.

Parental Transfer of the Antimicrobial Protein LBP/BPI Protects Biomphalaria glabrata Eggs against Oomycete Infections

C. Coustau, P. van West, J. Reichhart, 2013, PLoS pathogens.

Ecdysiotropic activity in brains and corpora cardiaca of larvae and adults of Locusta migratoria: in vitro assays

J. Reichhart, M. Charlet, 1986 .

L-canavanine incorporation into vitellogenin and macromolecular conformation.

J. Hoffmann, J. Reichhart, G. Rosenthal, 1989, The Journal of biological chemistry.

Production of monoclonal antibodies against Corpora cardiaca extracts of Locusta migratoria: a potential tool for the isolation of insect neurohormones

D. Zachary, F. Holder, M. Meister, 1988 .

Advances in Myeloid-Like Cell Origins and Functions in the Model Organism Drosophila melanogaster

J. Reichhart, Nicolas Matt, Laure El Chamy, 2017, Microbiology spectrum.

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis.

D. Zachary, C. Kopczynski, G. Duyk, 2001, Developmental cell.

Splice‐activated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in drosophila melanogaster

D. Gubb, S. Naitza, J. Imler, 2002, Genesis.

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.

A. Lacy-Hulbert, G. Charrière, J. Reichhart, 2011, Immunity.

Akirin2 is critical for inducing inflammatory genes by bridging IκB‐ζ and the SWI/SNF complex

S. Akira, D. Standley, O. Takeuchi, 2014, The EMBO journal.

Protein Phosphatase 4 Negatively Regulates the Immune Deficiency-NF-κB Pathway during the Drosophila Immune Response

J. Reichhart, Nicolas Matt, A. Acker, 2021, The Journal of Immunology.

Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll

J. Reichhart, I. Caldelari, L. Chamy, 2008, Nature Immunology.

Danger signal and PAMP sensing define binary signaling pathways upstream of Toll

J. Reichhart, I. Caldelari, L. Chamy, 2008, Nature immunology.

Akirins, highly conserved nuclear proteins, required for NF-κB dependent gene expression in Drosophila and mice

M. Boutros, S. Akira, O. Takeuchi, 2007, Nature Immunology.

Sensing and signaling during infection in Drosophila.

J. Hoffmann, J. Reichhart, J. Royet, 2005, Current opinion in immunology.

Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants

B. Lemaître, J. Reichhart, P. Tzou, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin.

P. Georgel, J. Hoffmann, J. Reichhart, 1996, Nucleic acids research.

Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila.

M. Meister, B. Lemaître, P. Georgel, 1993, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

Insect immunity. Two 17 bp repeats nesting a kappa B‐related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria‐challenged Drosophila.

M. Meister, M. Lagueux, J. Hoffmann, 1993, The EMBO journal.

Silencing of Toll pathway components by direct injection of double-stranded RNA into Drosophila adult flies.

E. Levashina, J. Reichhart, S. Blandin, 2003, Nucleic acids research.

The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway

A. van Dorsselaer, J. Reichhart, F. Veillard, 2018, Molecular cell.

Antibacterial activity of a dual peptide targeting the Escherichia coli sliding clamp and the ribosome

J. Wagner, G. Guichard, J. Reichhart, 2020, RSC chemical biology.

Dorsal-B, a splice variant of the Drosophila factor Dorsal, is a novel Rel/NF-kappaB transcriptional activator.

P. Georgel, J. Reichhart, I. Gross, 1999, Gene.

Growth stimulation of the immature chick oviduct by androgens: the vagina as a new target tissue.

J. Reichhart, J. Thiébold, Y. Grau, 1985, Journal of embryology and experimental morphology.

The Drosophila serpins: multiple functions in immunity and morphogenesis.

D. Gubb, J. Reichhart, V. Leclerc, 2011, Methods in enzymology.

Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice

M. Boutros, S. Akira, O. Takeuchi, 2008, Nature Immunology.

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling

O. Takeuchi, J. Camonis, X. Nguyen, 2014, The EMBO journal.

Specific versus Non-Specific Immune Responses in an Invertebrate Species Evidenced by a Comparative de novo Sequencing Study

C. Coustau, J. Gouzy, E. Wajnberg, 2012, PloS one.

Expression and secretion in yeast of active insect defensin, an inducible antibacterial peptide from the fleshfly Phormia terranovae

I. Petit, J. Hoffmann, J. Reichhart, 1992 .

Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983.

B. Lemaître, J. Hoffmann, J. Reichhart, 2012, Journal of immunology.

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection.

C. Sasakawa, T. Mizushima, Taira Kobayashi, 2013, Cell host & microbe.

A Serpin Regulates Dorsal-Ventral Axis Formation in the Drosophila Embryo

S. Roth, J. Reichhart, P. Ligoxygakis, 2003, Current Biology.

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes

J. Reichhart, P. Ligoxygakis, Marcus Glittenberg, 2009, Journal of Cell Science.

The immune response of Drosophila melanogaster

J. Reichhart, V. Leclerc, 2004, Immunological reviews.

Determination of disulfide bridges in natural and recombinant insect defensin A.

P. Lepage, C. Roitsch, J. Hoffmann, 1991, European journal of biochemistry.

Two-dimensional1H NMR study of recombinant insect defensin A in water: Resonance assignments, secondary structure and global folding

X. Gallet, M. Ptak, J. Hoffmann, 1992, Journal of biomolecular NMR.

Hyd ubiquitinates the NF-κB co-factor Akirin to activate an effective immune response in Drosophila

M. Boutros, A. Orian, X. Nguyen, 2018, bioRxiv.

Drosophila necrotic mutations mirror disease-associated variants of human serpins

D. Gubb, D. Lomas, J. Reichhart, 2003, Development.

A drosomycin–GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

B. Lemaître, S. Uttenweiler-Joseph, J. Reichhart, 1998, The EMBO journal.

Cg‐Rel, the first Rel/NF‐κB homolog characterized in a mollusk, the Pacific oyster Crassostrea gigas

J. Escoubas, J. Reichhart, C. Montagnani, 2004, FEBS letters.

Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic.

D. Gubb, D. Lomas, J. Reichhart, 2006, Insect biochemistry and molecular biology.

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter.

M. Meister, J. Hoffmann, J. Reichhart, 1994, The EMBO journal.

In Vivo Regulation of the IκB Homologuecactus during the Immune Response ofDrosophila *

B. Lemaître, J. Hoffmann, J. Reichhart, 1998, The Journal of Biological Chemistry.

Insect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides.

J. Reichhart, A. Dorsselaer, J. Dimarcq, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling.

J. Reichhart, P. Meier, N. Silverman, 2010, Molecular cell.

The LBP/BPI multigenic family in invertebrates: Evolutionary history and evidences of specialization in mollusks.

C. Coustau, J. Reichhart, E. Deleury, 2016, Developmental and comparative immunology.