M. Wermann

发表

Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.

S. Schilling, C. Lindner, B. Koch, 2007, Biochemistry.

Characterisation of Human Dipeptidyl Peptidase IV Expressed in Pichia pastoris. A Structural and Mechanistic Comparison between the Recombinant Human and the Purified Porcine Enzyme

T. Hoffmann, B. Gerhartz, M. Wermann, 2003, Biological chemistry.

Isolation of dipeptidyl peptidase IV (DP 4) isoforms from porcine kidney by preparative isoelectric focusing to improve crystallization

T. Hoffmann, M. Wermann, J. Rahfeld, 2011, Biological chemistry.

On combination therapy of diabetes with metformin and dipeptidyl peptidase IV inhibitors.

R. Pederson, C. Mcintosh, T. Hoffmann, 2002, Diabetes care.

Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis.

T. Yoshimoto, S. Schilling, M. Wermann, 2018, Analytical biochemistry.

Elevated TNF receptor plasma concentrations in patients with rheumatoid arthritis

M. Brockhaus, M. Wermann, H. Gallati, 2004, The clinical investigator.

Evaluation of soluble tumor necrosis factor receptors after orthotopic liver transplantation.

C. Herfarth, A. Mehrabi, G. Otto, 1992, Transplantation proceedings.

[Plasma GM-CSF concentrations in rheumatoid arthritis, systemic lupus erythematosus and spondyloarthropathy].

M. Hüfner, C. Fiehn, M. Wermann, 1992, Zeitschrift fur Rheumatologie.

Inhibition of glutaminyl cyclase prevents pGlu‐Aβ formation after intracortical/hippocampal microinjection in vivo/in situ

T. Hoffmann, W. Jagla, S. Schilling, 2008, Journal of neurochemistry.

Immunogenicity of the Envelope Surface Unit of Human Endogenous Retrovirus K18 in Mice

M. Wermann, H. Cynis, S. Roßner, 2022, International journal of molecular sciences.

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor

J. Whisstock, A. de Marco, C. Bayly-Jones, 2022, Nature Communications.

Expression, purification and initial characterization of human meprin β from Pichia pastoris.

S. Schilling, M. Wermann, D. Schlenzig, 2015, Protein expression and purification.

Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.

C. Parthier, M. Stubbs, S. Schilling, 2011, Biochemistry.

Continuous spectrometric assays for glutaminyl cyclase activity.

T. Hoffmann, C. Wasternack, S. Schilling, 2002, Analytical biochemistry.

Identification of Human Glutaminyl Cyclase as a Metalloenzyme

T. Hoffmann, C. Wasternack, S. Schilling, 2003, Journal of Biological Chemistry.

Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.

A. Kehlen, S. Schilling, B. Koch, 2008, Journal of molecular biology.

Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions

C. Wasternack, S. Schilling, M. Wermann, 2007, Biological chemistry.

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

Robert Huber, Hans-Ulrich Demuth, Ulrich Heiser, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro

M. Morawski, S. Schilling, M. Wermann, 2020, Molecules.

The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

P. Quax, T. Hoffmann, W. Jagla, 2011, EMBO molecular medicine.

Purification of recombinant Aβ(1‐42) and pGlu‐Aβ(3‐42) using preparative SDS‐PAGE

G. Hause, S. Schilling, M. Wermann, 2017, Electrophoresis.

Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation in Vitro by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry

R. Pederson, C. Mcintosh, M. Wermann, 1996, The Journal of Biological Chemistry.

Dipeptidyl-Peptidase Activity of Meprin β Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ Formation.

S. Schilling, M. Wermann, H. Demuth, 2018, Journal of Alzheimer's disease : JAD.

Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain

Hans-Ulrich Demuth, Maike Hartlage-Rübsamen, Steffen Roßner, 2009, International Journal of Developmental Neuroscience.

Probing Secondary Glutaminyl Cyclase (QC) Inhibitor Interactions Applying an in silico‐Modeling/Site‐Directed Mutagenesis Approach: Implications for Drug Development

S. Schilling, B. Koch, M. Wermann, 2012, Chemical biology & drug design.

Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics

S. Schilling, B. Koch, M. Wermann, 2009, The FEBS journal.

Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.

Hans-Ulrich Demuth, Mirko Buchholz, Ulrich Heiser, 2005, Biochemistry.

Does human attractin have DP4 activity?

T. Hoffmann, M. Wermann, H. Demuth, 2007, Biological chemistry.

Helical ultrastructure of the oncogenic metalloprotease meprin α in complex with a small molecule hydroxamate inhibitor

J. Whisstock, A. de Marco, C. Bayly-Jones, 2022, bioRxiv.

Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs.

C. Parthier, M. Stubbs, S. Schilling, 2012, Biochemistry.

Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor

C. Parthier, S. Schilling, M. Wermann, 2021, International journal of molecular sciences.