N. Daly

发表

Bioactive cystine knot proteins.

Norelle L Daly, David J Craik, D. Craik, 2011, Current opinion in chemical biology.

Exploring the therapeutic potential of jellyfish venom.

Norelle L Daly, N. Daly, J. Seymour, 2014, Future medicinal chemistry.

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds.

Julie H. Campbell, D. Craik, S. Henriques, 2011, Blood.

Disulfide Folding Pathways of Cystine Knot Proteins

D. Craik, N. Daly, R. Clark, 2003, The Journal of Biological Chemistry.

Twists, Knots, and Rings in Proteins

Clement Waine, Norelle L Daly, David J Craik, 2003, The Journal of Biological Chemistry.

Discovery, structure and biological activities of the cyclotides.

Jason Mulvenna, Norelle L Daly, David J Craik, 2004, Current protein & peptide science.

Albumins and their processing machinery are hijacked for cyclic peptides in sunflower.

D. Craik, N. Daly, M. Colgrave, 2011, Nature chemical biology.

The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions

Marilyn A. Anderson, D. Craik, N. Daly, 2014, BMC Plant Biology.

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.

D. Craik, J. Stow, N. Daly, 2007, The international journal of biochemistry & cell biology.

A C-Terminal Fragment of Chlorotoxin Retains Bioactivity and Inhibits Cell Migration

P. Giacomin, N. Daly, David T Wilson, 2019, Front. Pharmacol..

NMR of peptide toxins

D. Craik, K. Rosengren, N. Daly, 2009 .

Small Molecules in the Venom of the Scorpion Hormurus waigiensis

N. Daly, David T Wilson, T. Northfield, 2020, Biomedicines.

Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain.

N. Daly, P. Kroon, R. Smith, 1995, Biochemistry.

Three-dimensional structure of the second cysteine-rich repeat from the human low-density lipoprotein receptor.

N. Daly, P. Kroon, R. Smith, 1995, Biochemistry.

Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function.

D. Craik, David John Adams, R. Lewis, 2008, Journal of medicinal chemistry.

Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance.

D. Craik, N. Daly, P. Alewood, 1999, Journal of medicinal chemistry.

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease.

D. Craik, R. Hoffmann, L. Otvos, 2000, Biochemistry.

Decoding the Membrane Activity of the Cyclotide Kalata B1

D. Craik, Yen‐Hua Huang, K. Rosengren, 2011, The Journal of Biological Chemistry.

Characterisation of a Novel A-Superfamily Conotoxin

I. Vetter, A. Nicke, N. Daly, 2020, Biomedicines.

Structural Characterisation of Predicted Helical Regions in the Chironex fleckeri CfTX-1 Toxin

N. Daly, J. Seymour, David T Wilson, 2018, Marine drugs.

STRUCTURE AND FUNCTION OF PLANT TOXINS (WITH EMPHASIS ON CYSTINE KNOT TOXINS)

D. Craik, M. Plan, N. Daly, 2002 .

The Cyclotide Fingerprint in Oldenlandia affinis: Elucidation of Chemically Modified, Linear and Novel Macrocyclic Peptides

D. Craik, M. Plan, N. Daly, 2007, Chembiochem : a European journal of chemical biology.

Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus.

D. Craik, N. Daly, P. Alewood, 2014, Toxicon : official journal of the International Society on Toxinology.

Structure-activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359.

D. Gloriam, Xiao-Feng Xiong, K. Strømgaard, 2018, European journal of medicinal chemistry.

Identifying the immunomodulatory components of helminths

A. Loukas, S. Navarro, N. Daly, 2015, Parasite immunology.

A Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating Domain

G. Cao, M. Nitabach, S. Jordt, 2014, Current Biology.

Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.

M. Ammirati, D. Craik, David A. Price, 2014, Chemistry & biology.

θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation*

S. A. Gallo, D. Craik, A. Waring, 2006, Journal of Biological Chemistry.

Plant derived cyclic peptides

N. Daly, David T Wilson, David T. Wilson, 2021, Biochemical Society transactions.

Discovery of an unusual biosynthetic origin for circular proteins in legumes

R. Lyons, D. Craik, N. Daly, 2011, Proceedings of the National Academy of Sciences.

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

Marilyn A. Anderson, D. Craik, N. Daly, 2006, IUBMB life.

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Coral Venom Toxins

N. Daly, David T Wilson, C. Schmidt, 2019, Front. Ecol. Evol..

Transforming conotoxins into cyclotides: Backbone cyclization of P‐superfamily conotoxins

D. Craik, N. Daly, R. Clark, 2015, Biopolymers.

Backbone cyclization improves the enzymatic stability of chi-conotoxin, MrIA, whilst maintaining its structure and NET-modulating activity

D. Craik, N. Daly, M. Colgrave, 2006 .

Venomics: A Mini-Review

N. Daly, David T Wilson, David T. Wilson, 2018, High-throughput.

The chemistry and biology of cyclotides.

D. Craik, N. Daly, M. Cemazar, 2007, Current opinion in drug discovery & development.

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.

D. Craik, David John Adams, N. Daly, 2006, The Journal of biological chemistry.

Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds.

D. Craik, K. Rosengren, N. Daly, 2002, Biochemistry.

The cystine knot motif in toxins and implications for drug design.

D. Craik, N. Daly, C. Waine, 2001, Toxicon : official journal of the International Society on Toxinology.

Structural studies of cyclotides

K. Rosengren, N. Daly, 2015 .

Gly(6) of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes.

D. Craik, M. Aguilar, K. Hall, 2012, Biochimica et biophysica acta.

Cyclotides: a patent review

D. Craik, N. Daly, Amanda Smith, 2011, Expert opinion on therapeutic patents.

Design and therapeutic applications of cyclotides.

D. Craik, N. Daly, 2009, Future medicinal chemistry.

Alanine Scanning Mutagenesis of the Prototypic Cyclotide Reveals a Cluster of Residues Essential for Bioactivity*

D. Craik, K. Rosengren, Conan K. Wang, 2008, Journal of Biological Chemistry.

Discovery and structures of the cyclotides: novel macrocyclic peptides from plants

Marilyn A. Anderson, D. Craik, J. Mulvenna, 2001, Letters in Peptide Science.

Diversity in the disulfide folding pathways of cystine knot peptides

D. Craik, N. Daly, U. Göransson, 2006, Letters in Peptide Science.

The atypical α -conotoxin LtIA from C onus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor*

D. Craik, R. Lewis, N. Daly, 2010 .

NMR of Conotoxins: Structural Features and Analysis of Chemical Shifts of Posttranslationally Modified Amino Acids

D. Craik, U. Marx, N. Daly, 2006 .

Venom Costs and Optimization in Scorpions

N. Daly, David T Wilson, T. Northfield, 2019, Front. Ecol. Evol..

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.

D. Craik, N. Daly, B. Olivera, 2006, Biochemistry.

Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity.

A. Loukas, J. Tytgat, I. Cooke, 2022, Journal of natural products.

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

D. Craik, Q. Kaas, Yen‐Hua Huang, 2015, Scientific Reports.

Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells

A. Loukas, John J Miles, P. Giacomin, 2022, Frontiers in Medicine.

Approaches to delineate disulfide connectivities in pharmaceutical peptides

N. Daly, David T Wilson, David T. Wilson, 2018 .

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework.

D. Craik, J. Wade, K. Rosengren, 2009, The Biochemical journal.

Anthelminthic activity of the cyclotides (kalata B1 and B2) against schistosome parasites.

D. Craik, D. McManus, Malcolm K. Jones, 2013, Biopolymers.

Solution Structure and Novel Insights into the Determinants of the Receptor Specificity of Human Relaxin-3*

D. Craik, J. Wade, K. Rosengren, 2006, Journal of Biological Chemistry.

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding.

D. Craik, David John Adams, Gene Hopping, 2011, Angewandte Chemie.

Cyclotides as templates for peptide GPCR ligand design - discovery of the target receptor of the oxytocic plant peptide kalata B7

Terry J. Smith, D. Craik, S. Wray, 2013 .

Phosphatidylethanolamine Binding Is a Conserved Feature of Cyclotide-Membrane Interactions*

D. Craik, Yen‐Hua Huang, L. Bagatolli, 2012, The Journal of Biological Chemistry.

Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus

C. Enjalbal, A. Nicke, G. Laconde, 2018, Toxins.

Quantification of small cyclic disulfide‐rich peptides

D. Craik, N. Daly, A. C. Conibear, 2012, Biopolymers.

Structure of the second copper binding domain of the Menkes ATPase

Christopher E. Jones, D. Craik, P. Cobine, 2001 .

The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity*

D. Craik, K. Rosengren, S. Henriques, 2013 .

Structural Insights into the Function of Relaxins

D. Craik, J. Wade, K. Rosengren, 2009, Annals of the New York Academy of Sciences.

Structural Properties of Relaxin Chimeras

D. Craik, J. Wade, K. Rosengren, 2009, Annals of the New York Academy of Sciences.

Structure of the R3/I5 Chimeric Relaxin Peptide, a Selective GPCR135 and GPCR142 Agonist*

D. Craik, J. Wade, K. Rosengren, 2008, Journal of Biological Chemistry.

TEMPORARY REMOVAL: Anti-inflammatory properties of novel galloyl glucosides isolated from the Australian tropical plant Uromyrtus metrosideros

A. Loukas, N. Daly, D. Crayn, 2022, Chemico-Biological Interactions.

ApInAPDB: a database of apoptosis-inducing anticancer peptides

N. Daly, A. Khosroushahi, Naser Faraji, 2022, Scientific reports.

The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

A. Loukas, Jennifer J. Smith, P. Parsons, 2017, Toxins.

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure.

D. Craik, I. Vetter, R. Lewis, 2011, Journal of the American Chemical Society.

NMR and protein structure in drug design: application to cyclotides and conotoxins

D. Craik, K. Rosengren, S. Henriques, 2011, European Biophysics Journal.

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis.

D. Craik, M. Plan, K. Rosengren, 2010, Biopolymers.

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

Norelle L Daly, David J Craik, D. Craik, 2007, Expert opinion on investigational drugs.

NMR as a tool for elucidating the structures of circular and knotted proteins.

D. Craik, N. Daly, 2007, Molecular bioSystems.

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

Masa Cemazar, Norelle L Daly, David J Craik, 2006, Biopolymers.

Isolation and Characterization of Novel Cyclotides from Viola hederaceae

K. Gustafson, D. Craik, K. Rosengren, 2005, Journal of Biological Chemistry.

Conserved Structural and Sequence Elements Implicated in the Processing of Gene-encoded Circular Proteins*

Marilyn A. Anderson, Cameron V. Jennings, D. Craik, 2004, Journal of Biological Chemistry.

The role of the cyclic peptide backbone in the anti‐HIV activity of the cyclotide kalata B1

K. Gustafson, D. Craik, N. Daly, 2004, FEBS letters.

Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework.

K. Gustafson, D. Craik, N. Daly, 2004, Structure.

A Comparison of the Self-association Behavior of the Plant Cyclotides Kalata B1 and Kalata B2 via Analytical Ultracentrifugation*

D. Craik, M. Trabi, A. Nourse, 2004, Journal of Biological Chemistry.

Structure‐Function Studies of the Plant Cyclotides: The Role of a Circular Protein Backbone

D. Craik, N. Daly, R. Clark, 2003 .

Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone.

Ulf Göransson, Norelle L Daly, David J Craik, 2003, Journal of the American Chemical Society.

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

P. T. Choy, D. Craik, Jennifer L. Martin, 2010, Journal of the American Chemical Society.

α-Selenoconotoxins, a New Class of Potent α7 Neuronal Nicotinic Receptor Antagonists*

D. Craik, David John Adams, N. Daly, 2006, Journal of Biological Chemistry.

Structures of Naturally Occurring Circular Proteins from Bacteria

D. Craik, M. Trabi, K. Rosengren, 2003, Journal of bacteriology.

How do cyclotides exert their mode of action? the importance of cell membranes on their diverse activities

D. Craik, Yen‐Hua Huang, S. Henriques, 2009 .

Solution Structure, Membrane Interactions, and Protein Binding Partners of the Tetraspanin Sm-TSP-2, a Vaccine Antigen from the Human Blood Fluke Schistosoma mansoni*

A. Loukas, D. Craik, K. Rosengren, 2014, The Journal of Biological Chemistry.

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

Susan Wray, Terry J. Smith, Michael Freissmuth, 2013, Proceedings of the National Academy of Sciences.

Isolation and characterization of cytotoxic cyclotides from Viola philippica

D. Craik, G. Zeng, N. Tan, 2011, Peptides.

Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity.

K. Gustafson, M. Boyd, D. Craik, 1999, Journal of molecular biology.

Isolation and characterization of peptides from Momordica cochinchinensis seeds.

D. Craik, R. Lewis, Conan K. Wang, 2009, Journal of Natural Products.

Solution structure, aggregation behavior, and flexibility of human relaxin-2.

D. Craik, J. Wade, K. Rosengren, 2015, ACS chemical biology.

A new family of cystine knot peptides from the seeds of Momordica cochinchinensis

D. Craik, G. Zeng, N. Daly, 2013, Peptides.

Identification and Characterization of a New Family of Cell-penetrating Peptides

M. Sweet, D. Craik, Yen‐Hua Huang, 2011, The Journal of Biological Chemistry.

Cyclotides: macrocyclic peptides with applications in drug design and agriculture

D. Craik, N. Daly, J. Mylne, 2009, Cellular and Molecular Life Sciences.

Gastrointestinal Helminth Infection Improves Insulin Sensitivity, Decreases Systemic Inflammation, and Alters the Composition of Gut Microbiota in Distinct Mouse Models of Type 2 Diabetes

A. Loukas, L. Krause, P. Giacomin, 2021, Frontiers in Endocrinology.

Revisiting Inflammatory Bowel Disease: Pathology, Treatments, Challenges and Emerging Therapeutics Including Drug Leads from Natural Products

A. Loukas, N. Daly, Luke Hunter, 2020, Journal of clinical medicine.

Engineering of an Anti-Inflammatory Peptide Based on the Disulfide-Rich Linaclotide Scaffold

A. Loukas, N. Daly, David T Wilson, 2018, Biomedicines.

An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease

A. Loukas, P. Giacomin, S. Navarro, 2017, The Journal of Biological Chemistry.

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival.

D. Hume, M. Sweet, D. Craik, 2009, Molecular immunology.

Circular Proteins in Plants

D. Craik, N. Daly, D J Craik, 2001, The Journal of Biological Chemistry.

Inhibition of Neuronal Nicotinic Acetylcholine Receptor Subtypes by α-Conotoxin GID and Analogues*

D. Craik, David John Adams, R. Lewis, 2009, Journal of Biological Chemistry.

Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia

James L. Richards, C. Mackay, A. Ponsonby, 2019, Nature Communications.

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes

A. Loukas, John J Miles, M. McConville, 2019, Infection and Immunity.

Hookworm-derived small molecule extracts suppress pathology in a mouse model of colitis and inhibit secretion of key inflammatory cytokines in primary human leukocytes

A. Loukas, John J Miles, M. McConville, 2018, bioRxiv.

Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia

A. Loukas, C. Whitchurch, J. Golledge, 2015, PLoS pathogens.

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

R. Kumar, A. Loukas, O. Singh, 2020, Nature Immunology.

Conopressin-T from Conus tulipa Reveals an Antagonist Switch in Vasopressin-like Peptides*

D. Craik, R. Lewis, G. Guillon, 2008, Journal of Biological Chemistry.

Folding of granulin domains

A. Loukas, N. Daly, M. Dastpeyman, 2018 .

Folding of Truncated Granulin Peptides

A. Loukas, N. Daly, David T Wilson, 2020, Biomolecules.

Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.

A. Loukas, P. Brindley, J. Sotillo, 2017, Journal of medicinal chemistry.

Nuclear Magnetic Resonance seq (NMRseq): A New Approach to Peptide Sequence Tags

N. Daly, David T Wilson, David T. Wilson, 2018, Toxins.

A netrin domain-containing protein secreted by the human hookworm Necator americanus protects against CD4 T cell transfer colitis.

M. Field, A. Loukas, P. Giacomin, 2021, Translational research : the journal of laboratory and clinical medicine.

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.

D. Craik, N. Daly, C. Waine, 1999, Journal of molecular biology.

Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors.

M. Amar, C. Enjalbal, D. Servent, 2020, Journal of medicinal chemistry.

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration

D. Craik, N. Daly, L. Y. Chan, 2015, Bioscience reports.

IgE and IgG4 epitopes revealed on the major fish allergen Lat c 1.

N. Daly, A. Lopata, M. F. Sharp, 2021, Molecular immunology.

RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs.

D. Craik, David John Adams, N. Daly, 2012, Biochemical pharmacology.

Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter.

Michelle L Colgrave, Norelle L Daly, David J Craik, 2006, Journal of medicinal chemistry.

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif.

Norelle L Daly, David J Craik, D. Craik, 2006, The Biochemical journal.

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

Philipp M. Cromm, A. Plowright, D. Craik, 2018, Journal of medicinal chemistry.

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions.

D. Craik, P. Harvey, K. Rosengren, 2013, Biopolymers.

Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1*

D. Craik, T. Andresen, B. Wulff, 2012, The Journal of Biological Chemistry.

A Synthetic Mirror Image of Kalata B1 Reveals that Cyclotide Activity Is Independent of a Protein Receptor

K. Gustafson, D. Craik, M. Aguilar, 2011, Chembiochem : a European journal of chemical biology.

Analysis of cyclotides in Viola ignobilis by Nano liquid chromatography fourier transform mass spectrometry.

B. Spengler, N. Daly, A. Ghassempour, 2011, Protein and peptide letters.

Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins.

D. Craik, N. Daly, M. Colgrave, 2011, ACS chemical biology.

Cystine knot folding in cyclotides

D. Craik, N. Daly, U. Göransson, 2011 .

Structure and Activity of the Leaf-Specific Cyclotide vhl-2

D. Craik, N. Daly, Bin Chen, 2010 .

The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores*

D. Craik, Yen‐Hua Huang, B. Martinac, 2009, The Journal of Biological Chemistry.

Dissecting the oxidative folding of circular cystine knot miniproteins.

D. Craik, N. Daly, S. Gunasekera, 2009, Antioxidants & redox signaling.

Discovery, structure and biological activities of cyclotides.

D. Craik, K. Rosengren, N. Daly, 2004, Advanced drug delivery reviews.

Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins.

D. Craik, N. Daly, M. Colgrave, 2006, Journal of molecular biology.

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

D. Craik, N. Daly, R. Clark, 2006, The Biochemical journal.

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

Clement Waine, Cameron V. Jennings, Martin J Scanlon, 2005, Biochemistry.

Structure of Circulin B and Implications for Antimicrobial Activity of the Cyclotides

K. Gustafson, D. Craik, N. Daly, 2004, International Journal of Peptide Research and Therapeutics.

Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity.

D. Craik, N. Daly, R. Clark, 2003, Biochemistry.

Acyclic Permutants of Naturally Occurring Cyclic Proteins

David J. Craik, Norelle L. Daly, D. Craik, 2000, The Journal of Biological Chemistry.

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

D. Craik, G. Zeng, N. Tan, 2010, Peptides.

Capped acyclic permutants of the circular protein kalata B1

D. Craik, N. Daly, Shane M. Simonsen, 2004, FEBS letters.

Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.

D. Craik, David John Adams, N. Daly, 2011, Journal of medicinal chemistry.

Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

Norelle L Daly, David J Craik, Harald Fischer, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Voltage-Gated Sodium Channel Modulation by a New Spider Toxin Ssp1a Isolated From an Australian Theraphosid

R. Lewis, N. Daly, David T Wilson, 2021, Frontiers in Pharmacology.

Structure and Activity of α-Conotoxin PeIA at Nicotinic Acetylcholine Receptor Subtypes and GABAB Receptor-coupled N-type Calcium Channels*

D. Craik, David John Adams, N. Daly, 2011, The Journal of Biological Chemistry.

Novel Inhibitor Cystine Knot Peptides from Momordica charantia

D. Craik, O. Franco, G. Zeng, 2013, PloS one.

Isolation of an Orally Active Insecticidal Toxin from the Venom of an Australian Tarantula

G. King, N. Daly, M. Mobli, 2013, PloS one.

Structural studies of conotoxins

Norelle L Daly, David J Craik, D. Craik, 2009, IUBMB life.

The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein.

A. Mark, D. Craik, N. Daly, 2008, Structure.

Knots in Rings

D. Craik, E. Yulyaningsih, N. Daly, 2006, Journal of Biological Chemistry.

University of Groningen The Structure of a Two-Disulfide Intermediate Assists in Elucidating the Oxidative Folding Pathway of a Cyclic Cystine Know Protein Cernazar,

A. Mark, D. Craik, N. Daly, 2022 .

Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides.

D. Craik, L. Fabri, N. Daly, 2008, Journal of medicinal chemistry.

Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor*

D. Craik, Jennifer L. Martin, K. Rosengren, 2013, Journal of Biological Chemistry.

Solution structure of the toxic octapeptide, lophyrotomin.

N. Daly, A. Atkins, R. Smith, 2009, International journal of peptide and protein research.

Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia

James L. Richards, C. Mackay, A. Ponsonby, 2019, Nature Communications.

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

D. Craik, David John Adams, R. Lewis, 2004, The Journal of biological chemistry.

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

D. Craik, Q. Kaas, T. Durek, 2015, Nature Communications.

Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors.

D. Craik, I. Vetter, David John Adams, 2013, Biochemical pharmacology.

Isolation, Structure, and Activity of GID, a Novel α4/7-Conotoxin with an Extended N-terminal Sequence*

D. Craik, David John Adams, R. Lewis, 2003, The Journal of Biological Chemistry.

α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.

I. Vetter, R. Lewis, N. Daly, 2015, Biochemical pharmacology.

Atypical α-Conotoxin LtIA from Conus litteratus Targets a Novel Microsite of the α3β2 Nicotinic Receptor*

D. Craik, R. Lewis, N. Daly, 2010, The Journal of Biological Chemistry.

Isolation, sequencing, and structure-activity relationships of cyclotides.

D. Craik, N. Daly, R. Clark, 2010, Journal of natural products.

The Absolute Structural Requirement for a Proline in the P3′-position of Bowman-Birk Protease Inhibitors Is Surmounted in the Minimized SFTI-1 Scaffold*

Norelle L Daly, David J Craik, D. Craik, 2006, Journal of Biological Chemistry.

High-affinity Cyclic Peptide Matriptase Inhibitors*

D. Craik, Q. Kaas, Yen‐Hua Huang, 2013, The Journal of Biological Chemistry.

Development of cyclic peptide matriptase inhibitors

D. Craik, Q. Kaas, Yen‐Hua Huang, 2013 .

Structural diversity of arthropod venom toxins.

N. Daly, David T Wilson, David T. Wilson, 2018, Toxicon : official journal of the International Society on Toxinology.

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1

D. Craik, Liqing Chen, E. Meehan, 2011, BMC Structural Biology.

A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus.

Brendan L Wilkinson, R. Kini, R. Payne, 2015, Angewandte Chemie.

Chemical Synthesis and Structure of the Prokineticin Bv8

D. Craik, I. Vetter, T. Durek, 2010, Chembiochem : a European journal of chemical biology.

Characterizing circular peptides in mixtures: sequence fragment assembly of cyclotides from a violet plant by MALDI-TOF/TOF mass spectrometry

Norelle L. Daly, Alireza Ghassempour, N. Daly, 2012, Amino Acids.

The cyclotides and related macrocyclic peptides as scaffolds in drug design.

Masa Cemazar, Norelle L Daly, David J Craik, 2006, Current opinion in drug discovery & development.

Conopeptides as novel options for pain management

D. Craik, N. Daly, 2011 .

Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter.

Mehdi Mobli, Norelle L Daly, R. Lewis, 2013, Angewandte Chemie.

The A-chain of Human Relaxin Family Peptides Has Distinct Roles in the Binding and Activation of the Different Relaxin Family Peptide Receptors*

J. Wade, K. Rosengren, N. Daly, 2008, Journal of Biological Chemistry.

In Vivo Efficacy of Anuran Trypsin Inhibitory Peptides against Staphylococcal Skin Infection and the Impact of Peptide Cyclization

D. Craik, O. Franco, O. N. Silva, 2015, Antimicrobial Agents and Chemotherapy.

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

Norelle L Daly, David J Craik, James M Olson, 2011, Journal of medicinal chemistry.

Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

D. Craik, N. Daly, L. Y. Chan, 2016, Scientific Reports.

Cyclization of the Antimicrobial Peptide Gomesin with Native Chemical Ligation: Influences on Stability and Bioactivity

D. Craik, N. Waters, Yen‐Hua Huang, 2013, Chembiochem : a European journal of chemical biology.

Isolation and characterization of bioactive cyclotides from Viola labridorica.

D. Craik, G. Zeng, N. Tan, 2010 .

Engineering of conotoxins for the treatment of pain.

D. Craik, P. Harvey, Q. Kaas, 2011, Current pharmaceutical design.

Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization.

D. Craik, N. Daly, S. Gunasekera, 2011, Antioxidants & redox signaling.

Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina.

D. Craik, K. Rosengren, N. Daly, 2001, Biochemistry.

Identification and Characterization of a Peptide from the Stony Coral Heliofungia actiniformis.

A. Loukas, John J Miles, J. Tytgat, 2020, Journal of natural products.

Solution Structure and Characterization of the LGR8 Receptor Binding Surface of Insulin-like Peptide 3*

D. Craik, J. Wade, K. Rosengren, 2006, Journal of Biological Chemistry.

Characterizing circular peptides in mixtures: sequence fragment assembly of cyclotides from a violet plant by MALDI-TOF/TOF mass spectrometry

N. Daly, C. Gruber, J. Koehbach, 2012, Amino Acids.

Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

D. Craik, N. Daly, P. Alewood, 1999, Biochemistry.

The cyclotides: novel macrocyclic peptides as scaffolds in drug design.

Norelle L Daly, David J Craik, D. Craik, 2002, Current opinion in drug discovery & development.

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

D. Craik, V. Hruby, Q. Kaas, 2020 .

The N‐terminal pro‐domain of the kalata B1 cyclotide precursor is intrinsically unstructured

D. Craik, J. Wade, N. Daly, 2016, Biopolymers.

The Cyclic Cystine Ladder in θ-Defensins Is Important for Structure and Stability, but Not Antibacterial Activity*

Norelle L Daly, David J Craik, D. Craik, 2013, The Journal of Biological Chemistry.

Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase–Mediated Biosynthesis[C][W]

Timothy L Bailey, Norelle L Daly, David J Craik, 2012, Plant Cell.

Disulfide Bridges: Bringing Together Frustrated Structure in a Bioactive Peptide.

K. Schulten, M. Gruebele, N. Daly, 2016, Biophysical journal.

Structural Variants of a Liver Fluke Derived Granulin Peptide Potently Stimulate Wound Healing.

A. Loukas, P. Brindley, J. Sotillo, 2018, Journal of medicinal chemistry.

Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1

A. Loukas, N. Daly, P. Bansal, 2023, Exploration of Drug Science.

Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.

David J. Craik, Norelle L. Daly, D. Craik, 2004, European journal of biochemistry.

Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor.

N. Daly, M. Scanlon, P. Kroon, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics

D. Craik, David John Adams, N. Daly, 2007, BMC Structural Biology.

scaffolds Engineering pro-angiogenic peptides using stable disulfide-rich cyclic

Julie H. Campbell, D. Craik, S. Henriques, 2012 .

The three‐dimensional structure of the analgesic α‐conotoxin, RgIA

D. Craik, David John Adams, N. Daly, 2008, FEBS letters.

Retrocyclin-2: structural analysis of a potent anti-HIV theta-defensin.

Wei Wang, Norelle L Daly, David J Craik, 2007, Biochemistry.

Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.

H. Vogel, D. Craik, A. Ouellette, 2006, The Journal of biological chemistry.

NMR of conotoxins: structural features and an analysis of chemical shifts of post‐translationally modified amino acids

D. Craik, U. Marx, N. Daly, 2006, Magnetic resonance in chemistry : MRC.

Synthesis, Structural and Pharmacological Characterizations of CIC, a Novel α-Conotoxin with an Extended N-Terminal Tail

C. Enjalbal, A. Nicke, N. Daly, 2021, Marine drugs.

STRUCTURE AND ACTIVITY OF α -CONOTOXIN PeIA AT NICOTINIC ACETYLCHOLINE RECEPTOR SUBTYPES AND GABA B RECEPTOR-COUPLED N-TYPE CALCIUM CHANNELS

D. Craik, David John Adams, N. Daly, 2010 .

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity.

A. Loukas, I. Vetter, R. Lewis, 2017, Angewandte Chemie.

Structure and Biological Activity of a Turripeptide from Unedogemmula bisaya Venom.

N. Daly, B. Olivera, M. Flores, 2017, Biochemistry.

The structure of microcin J25 is a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone

D. Craik, K. Rosengren, N. Daly, 2003 .

Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter.

D. Craik, K. Nilsson, R. Lewis, 2005, Biopolymers.

Effects of arginine 10 to lysine substitution on ω‐conotoxin CVIE and CVIF block of Cav2.2 channels

D. Craik, David John Adams, N. Daly, 2014, British journal of pharmacology.

Tyrosine-rich Conopeptides Affect Voltage-gated K+ Channels*

D. Craik, N. Daly, B. Olivera, 2008, Journal of Biological Chemistry.

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

D. Craik, A. Ouellette, K. Rosengren, 2012, Amino Acids.

Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris

C. Enjalbal, R. Lewis, N. Daly, 2020, Marine drugs.

Oxidative folding of the cystine knot motif in cyclotide proteins.

D. Craik, N. Daly, 2005, Protein and peptide letters.

Structures of μO-conotoxins from Conus marmoreus

D. Craik, David John Adams, R. Lewis, 2004, Journal of Biological Chemistry.

ampir: an R package for fast genome-wide prediction of antimicrobial peptides

David J. Miller, Legana C.H.W Fingerhut, Jan M. Strugnell, 2020, bioRxiv.

Solution structure of the N-terminal extension domain of a Schistosoma japonicum asparaginyl-tRNA synthetase.

A. Loukas, M. Liddell, N. Daly, 2023, Journal of biomolecular structure & dynamics.

SOLUTION STRUCTURE OF MCOTI-II, A MACROCYCLIC TRYPSIN INHIBITOR

D. Craik, N. Daly, M. E. Felizmenio-Quimio, 2001 .

Synthesis and Structural Analysis of the N-Terminal Domain of the Thyroid Hormone-Binding Protein Transthyretin

D. Craik, J. Wilce, N. Daly, 2002, Clinical chemistry and laboratory medicine.

Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1*

D. Craik, T. Andresen, B. Wulff, 2012, The Journal of Biological Chemistry.

Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor*

D. Craik, K. Rosengren, N. Daly, 2013, The Journal of Biological Chemistry.

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions.

D. Craik, P. Harvey, K. Rosengren, 2013, Biopolymers.

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

J. Olson, D. Craik, N. Daly, 2011, Journal of medicinal chemistry.

The Cyclic Cystine Ladder in (cid:1) -Defensins Is Important for Structure and Stability, but Not Antibacterial Activity *

D. Craik, K. Rosengren, S. Henriques, 2020 .

Chemical synthesis and structure elucidation of bovine κ-casein (1–44)☆

D. Craik, N. Daly, P. Alewood, 2006 .

Structure and metal binding studies of the second copper binding domain of the Menkes ATPase.

Christopher E. Jones, D. Craik, P. Cobine, 2003, Journal of structural biology.

Effects of arginine 10 to lysine substitution on ω‐conotoxin CVIE and CVIF block of Cav2.2 channels

D. Craik, David John Adams, N. Daly, 2014, British journal of pharmacology.

Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV1.7 and hCaV3 voltage‐gated channels

I. Vetter, C. Schroeder, N. Daly, 2023, The FEBS journal.