C. Contreras-Martel

发表

Structural characterization of the sporulation protein GerM from Bacillus subtilis.

D. Rudner, C. Mas, C. Morlot, 2018, Journal of structural biology.

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.

C. Contreras-Martel, D. Patin, D. Blanot, 2011, ACS medicinal chemistry letters.

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.

S. Turk, D. Mengin-Lecreulx, C. Contreras-Martel, 2013, European journal of medicinal chemistry.

Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).

C. Contreras-Martel, D. Blanot, A. Dessen, 2011, Journal of medicinal chemistry.

Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase.

M. Hervé, C. Contreras-Martel, D. Blanot, 2007, Journal of molecular biology.

Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.

C. Contreras-Martel, D. Blanot, A. Dessen, 2008, Journal of medicinal chemistry.

Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.

B. Joris, S. Grdadolnik, C. Contreras-Martel, 2011, European journal of medicinal chemistry.

Penicillin-binding proteins and beta-lactam resistance.

T. Vernet, A. Zapun, C. Contreras-Martel, 2008, FEMS microbiology reviews.

Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa

Claire Gendrin, C. Contreras-Martel, A. Dessen, 2012, PLoS pathogens.

Penicillin binding proteins: key players in bacterial cell cycle and drug resistance processes.

Otto Dideberg, O. Dideberg, P. Macheboeuf, 2006, FEMS microbiology reviews.

Molecular architecture of the PBP2–MreC core bacterial cell wall synthesis complex

C. Contreras-Martel, I. Boneca, A. Dessen, 2017, Nature Communications.

Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate.

E. Chabrière, J. Fontecilla-Camps, C. Contreras-Martel, 2006, Structure.

Bacterial secretins: Mechanisms of assembly and membrane targeting

P. Macheboeuf, C. Contreras-Martel, A. Dessen, 2020, Protein science : a publication of the Protein Society.

Penicillin-Binding Proteins (PBPs) and Bacterial Cell Wall Elongation Complexes.

C. Contreras-Martel, A. Dessen, M. M. Miyachiro, 2019, Sub-cellular biochemistry.

Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited

C. Contreras-Martel, D. Blanot, A. Dessen, 2016, PloS one.

Penicillin-binding protein 2x of Streptococcus pneumoniae: three new mutational pathways for remodelling an essential enzyme into a resistance determinant.

J. Frère, C. Contreras-Martel, M. P. van der Linden, 2008, Journal of molecular biology.

PBP active site flexibility as the key mechanism for beta-lactam resistance in pneumococci.

C. Dahout-Gonzalez, C. Contreras-Martel, A. Dessen, 2009, Journal of molecular biology.

The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization.

T. Vernet, A. D. Di Guilmi, I. Ferlenghi, 2012, The Biochemical journal.

Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system

G. Schoehn, L. F. Estrozi, C. Contreras-Martel, 2019, PLoS pathogens.

Pyruvate–Ferredoxin Oxidoreductase

E. Chabrière, J. Fontecilla-Camps, C. Contreras-Martel, 2011 .

Structure of the heterotrimeric complex that regulates type III secretion needle formation

J. Simorre, C. Contreras-Martel, A. Dessen, 2007, Proceedings of the National Academy of Sciences.

Tandem use of X‐ray crystallography and mass spectrometry to obtain ab initio the complete and exact amino acids sequence of HPBP, a human 38‐kDa apolipoprotein

D. Rochu, F. Renault, M. Elias, 2007, Proteins.

Combined Structural Analysis and Molecular Dynamics Reveal Penicillin-Binding Protein Inhibition Mode with β-Lactones.

Erin E. Carlson, Elizabeth A Ambrose, C. Contreras-Martel, 2022, ACS chemical biology.

Serendipitous discovery and X-ray structure of a human phosphate binding apolipoprotein.

J. Dupuy, D. Rochu, F. Renault, 2006, Structure.

Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae

E. Breukink, C. Morlot, K. Peters, 2018, Nature Communications.

Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae.

T. Vernet, O. Dideberg, A. D. Di Guilmi, 2006, Journal of molecular biology.

Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumoniae.

T. Vernet, A. D. Di Guilmi, C. Contreras-Martel, 2010, Structure.

Structure of a widely conserved type IV pilus biogenesis factor that affects the stability of secretin multimers.

C. Contreras-Martel, A. Dessen, V. Job, 2008, Journal of molecular biology.

Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA).

A. Luxen, B. Joris, C. Schofield, 2011, ACS chemical biology.

Self-association of MreC as a regulatory signal in bacterial cell wall elongation

G. Schoehn, L. F. Estrozi, C. Contreras-Martel, 2021, Nature Communications.

Self-association of MreC as a regulatory signal in bacterial cell wall elongation

G. Schoehn, L. F. Estrozi, C. Contreras-Martel, 2021, Nature Communications.

New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.

C. Contreras-Martel, D. Patin, D. Blanot, 2011, European journal of medicinal chemistry.

Structural Motif among All Siphophages Protein of Bacteriophage T5: a Conserved Crystal Structure of pb9, the Distal Tail

E. Girard, F. Vellieux, R. Lurz, 2014 .

Crystal Structure of pb9, the Distal Tail Protein of Bacteriophage T5: a Conserved Structural Motif among All Siphophages

E. Girard, F. Vellieux, R. Lurz, 2013, Journal of Virology.

Substitutions in PBP2b from β-Lactam-resistant Streptococcus pneumoniae Have Different Effects on Enzymatic Activity and Drug Reactivity*

E. Breukink, A. Zapun, C. Contreras-Martel, 2017, The Journal of Biological Chemistry.

Structural insights into ring-building motif domains involved in bacterial sporulation.

C. Mas, C. Morlot, M. Serrano, 2021, Journal of structural biology.

Structural Basis of Lipid Targeting and Destruction by the Type V Secretion System of Pseudomonas aeruginosa.

S. Zouhir, C. Contreras-Martel, S. Bleves, 2016, Journal of molecular biology.

MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.

N. Thielens, C. Contreras-Martel, A. Dessen, 2013, Environmental microbiology.

Structural-functional analysis of the oligomeric protein R-phycoerythrin.

M. Bunster, C. Contreras-Martel, J. Martínez-Oyanedel, 2004, Biological research.

Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniae.

Guy Schoehn, T. Vernet, G. Schoehn, 2008, Structure.

The structure at 2 A resolution of Phycocyanin from Gracilaria chilensis and the energy transfer network in a PC-PC complex.

M. Bunster, C. Contreras-Martel, D. Almonacid, 2007, Biophysical chemistry.

Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin

T. Vernet, J. Kleman, A. D. Di Guilmi, 2017, Scientific Reports.

Crystallization and 2.2 A resolution structure of R-phycoerythrin from Gracilaria chilensis: a case of perfect hemihedral twinning.

M. Bunster, J. Fontecilla-Camps, Pierre Legrand, 2001, Acta crystallographica. Section D, Biological crystallography.

MagC is a NplC/P60‐like member of the α‐2‐macroglobulin Mag complex of Pseudomonas aeruginosa that interacts with peptidoglycan

S. Zouhir, P. Macheboeuf, C. Contreras-Martel, 2021, FEBS letters.

Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin.

P. Macheboeuf, C. Contreras-Martel, A. Dessen, 2023, Structure.

Serendipitous discovery of a human phosphate binding apolipoprotein

J. Dupuy, D. Rochu, F. Renault, 2006 .

MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.

N. Thielens, C. Contreras-Martel, A. Dessen, 2013, Environmental microbiology.