J. Heersche

J. Aubin, K. L. Lee, J. Heersche, 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Calcitonin and the formation of 3',5'-AMP in bone and kidney.

J. Heersche, G. Aurbach, R. Marcus, 1974, Endocrinology.

Pregnancy‐associated plasma protein‐A proteolytic activity in rat vertebral cell cultures: Stimulation by dexamethasone–a potential mechanism for glucocorticoid regulation of osteoprogenitor proliferation and differentiation

J. Heersche, D. Jia, 2005, Journal of cellular physiology.

Differential chemotactic responses of different populations of fetal rat calvaria cells to platelet-derived growth factor and transforming growth factor beta.

J. Aubin, J. Heersche, F. Hughes, 1992, Bone and mineral.

Parathyroid hormone reversibly suppresses the differentiation of osteoprogenitor cells into functional osteoblasts.

J. Aubin, C. G. Bellows, J. Heersche, 1990, Endocrinology.

Different Effects of Insulin and Insulin-Like Growth Factors I and II on Osteoprogenitors and Adipocyte Progenitors in Fetal Rat Bone Cell Populations

C. G. Bellows, J. Heersche, D. Jia, 2006, Calcified Tissue International.

The Frequency of Common Progenitors for Adipocytes and Osteoblasts and of Committed and Restricted Adipocyte and Osteoblast Progenitors in Fetal Rat Calvaria Cell Populations *

C. G. Bellows, J. Heersche, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Insulin-like growth factor-1 and -2 stimulate osteoprogenitor proliferation and differentiation and adipocyte formation in cell populations derived from adult rat bone.

J. Heersche, D. Jia, 2000, Bone.

Expression of mRNAs for type-I collagen, bone sialoprotein, osteocalcin, and osteopontin at different stages of osteoblastic differentiation and their regulation by 1,25 dihydroxyvitamin D3

C. G. Bellows, J. Heersche, S. Reimers, 1999, Cell and Tissue Research.

The effects of sodium butyrate on the retinoic acid-induced changes in 1,25-dihydroxyvitamin D3 receptors in tumorigenic and nontumorigenic bone derived cell lines.

K. L. Lee, J. Heersche, P. Petkovich, 1988, Endocrinology.

Effects of Vitaxin®, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro

S. Dixon, S. Sims, J. Heersche, 2007, Journal of cellular biochemistry.

Chronic Extracellular Acidosis Induces Plasmalemmal Vacuolar Type H+ ATPase Activity in Osteoclasts*

S. Grinstein, G. Brisseau, O. Rotstein, 1997, The Journal of Biological Chemistry.

Modulation by retinoic acid of 1,25-dihydroxyvitamin D3 effects on alkaline phosphatase activity and parathyroid hormone responsiveness in an osteoblast-like osteosarcoma cell line.

J. Heersche, A. Grigoriadis, P. Petkovich, 1986, Endocrinology.

Characterization of the 1,25-(OH)2D3-induced inhibition of bone nodule formation in long-term cultures of fetal rat calvaria cells.

J. Aubin, C. G. Bellows, J. Heersche, 1993, Endocrinology.

Plasma vitamin D metabolite levels in phosphorus deficient rats during the development of vitamin D deficient rickets.

J. Harrison, J. Heersche, C. S. Tam, 1982, Metabolism: clinical and experimental.

A primary role for microfilaments, but not microtubules, in hormone-induced cytoplasmic retraction.

J. Aubin, J. Heersche, E. Alders, 1983, Experimental cell research.

Progesterone-mediated stimulation of osteoprogenitor proliferation and differentiation in cell populations derived from adult or fetal rat bone tissue depends on the serum component of the culture media

C. G. Bellows, J. Heersche, I. Tertinegg, 2005, Osteoporosis International.

Progesterone stimulates proliferation and differentiation of osteoprogenitor cells in bone cell populations derived from adult female but not from adult male rats.

J. Heersche, Y. Ishida, 1997, Bone.

Expression of insulin-like growth factor system constituents in differentiating rat osteoblastic cell populations.

J. Heersche, D. Jia, 2002, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Parathyroid Hormone- and Prostaglandin E1-Response in a Selected Population of Bone Cells After Repeated Subculture and Storage at ‒80 C

D. Brunette, J. Heersche, B. Ng, 1977 .

Effect of medium pH on osteoclast activity and osteoclast formation in cultures of dispersed rabbit osteoclasts

J. Heersche, T. Shibutani, T. Shibutani, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Retinoic acid responsiveness of cells and tissues in developing fetal limbs evaluated in a RAREhsplacZ transgenic mouse model

J. Heersche, H. Schroeder, 1998, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The Role of Cells in the Calcification Process

Howard C. Tenenbaum, J. Aubin, C. G. Bellows, 1990 .

Isolation of three species of proteoglycan synthesized by cloned bone cells.

J. Aubin, J. Heersche, G. Hunter, 1983, Biochemistry.

The effect of reloading on bone volume, osteoblast number, and osteoprogenitor characteristics: studies in hind limb unloaded rats.

C. G. Bellows, J. Heersche, Yongheng Jia, 2005, Bone.

Progesterone and dexamethasone stimulate proliferation and differentiation of osteoprogenitors and progenitors for adipocytes and macrophages in cell populations derived from adult rat vertebrae

J. Heersche, I. Tertinegg, Y. Ishida, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pharmacologic Doses of Medroxyprogesterone May Cause Bone Loss Through Glucocorticoid Activity: An Hypothesis

J. Heersche, Y. Ishida, 2002, Osteoporosis International.

Progesterone- and dexamethasone-dependent osteoprogenitors in bone cell populations derived from rat vertebrae are different and distinct.

J. Heersche, Y. Ishida, 1999, Endocrinology.

The effect of vitamin D restriction and repletion on bone apposition in the rat and its dependence on parathyroid hormone.

J. Heersche, G. Jones, C. Tam, 1981, Endocrinology.

Hypercalcemia with ovarian carcinoma: Evidence of a pathogenetic role for prostaglandins

J. Heersche, R. Josse, T. Murray, 1981, Cancer.

The effect of imidazole and imidazole-analogues on bone resorption in vitro: A suggested role for thromboxane A2

J. Heersche, D. Jez, 1981 .

The a3 Isoform of the 100-kDa V-ATPase Subunit Is Highly but Differentially Expressed in Large (≥10 Nuclei) and Small (≤5 Nuclei) Osteoclasts*

Yeqi Yao, J. Heersche, Hesheng Yu, 2003, Journal of Biological Chemistry.

Differentiation of osteoblasts and formation of mineralized bone in vitro

Howard C. Tenenbaum, J. Heersche, 1982, Calcified Tissue International.

Parathyroid hormone stimulates dentin and bone apposition in the thyroparathyroidectomized rat in a dose-dependent fashion

J. Heersche, C. S. Tam, T. Howley, 1983, Calcified Tissue International.

Effects of bone in vitro of bovine parathyroid hormone and synthetic fragments representing residues 1-34, 2-34 and 3-34.

J. Potts, J. Heersche, J. Parsons, 1976, Endocrine research communications.

Dexamethasone stimulates osteogenesis in chick periosteum in vitro.

Howard C. Tenenbaum, J. Heersche, 1985, Endocrinology.

Quantitative assessment of post-extraction healing and alveolar ridge remodelling of the mandible in female rats.

J. Heersche, E. S. Elsubeihi, E. Elsubeihi, 2004, Archives of oral biology.

Interleukin‐1α stimulates the release of prostaglandin E2 and phospholipase A2 from fetal rat calvarial cells in vitro: Relationship to bone nodule formation

J. Aubin, P. Vadas, W. Pruzanski, 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effects of dexamethasone on expression and maintenance of cartilage in serum-containing cultures of calvaria cells

J. Aubin, C. G. Bellows, J. Heersche, 1989, Cell and Tissue Research.

Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone

J. Aubin, J. Heersche, A. Grigoriadis, 1988, The Journal of cell biology.

CHAPTER 2 – Bone Cell Biology: Osteoblasts, Osteocytes, and Osteoclasts

Jane E. Aubin, J. Aubin, J. Heersche, 2003 .

Isolation of bone cell clones with differences in growth, hormone responses, and extracellular matrix production

J. Aubin, J. Heersche, J. Sodek, 1982, The Journal of cell biology.

The recovery of hormone responsiveness in desensitized neonatal rat calvariae.

J. Heersche, D. Jez, 1983, Endocrinology.

The effect of cortisol on the adenosine 3',5'-monophosphate response to parathyroid hormone of bone in vitro.

J. Heersche, B. Ng, J. Hekkelman, 1979, Endocrinology.

Differentiation of osteoid-producing cellsin vitro: Possible evidence for the requirement of a microenvironment

Howard C. Tenenbaum, J. Heersche, 1986, Calcified Tissue International.

Proteoglycan synthesis and deposition in fetal rat bone.

J. Aubin, J. Heersche, G. Hunter, 1984, Biochemistry.

Glucocorticoid‐Induced Osteoporosis: Both In Vivo and In Vitro Concentrations of Glucocorticoids Higher Than Physiological Levels Attenuate Osteoblast Differentiation

J. Heersche, Y. Ishida, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Differential effects of fluoride during initiation and progression of mineralization of osteoid nodules formed in vitro

C. G. Bellows, J. Heersche, J. Aubin, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Aluminum Accelerates Osteoblastic Differentiation But is Cytotoxic in Long-Term Rat Calvaria Cell Cultures

J. Aubin, C. G. Bellows, J. Heersche, 1999, Calcified Tissue International.

Aluminum inhibits both initiation and progression of mineralization of osteoid nodules formed in differentiating rat calvaria cell cultures

C. G. Bellows, J. Heersche, J. Aubin, 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Subclone heterogeneity in a clonally-derived osteoblast-like cell line.

J. Aubin, J. Heersche, A. Grigoriadis, 1985, Bone.

Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate.

J. Aubin, C. G. Bellows, J. Heersche, 1991, Bone and mineral.

Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration.

J. Heersche, J. Parsons, J A Parsons, 1982, Endocrinology.

OSTEOBLASTIC CELL LINEAGE

J. Aubin, K. Turksen, J. Heersche, 1993 .

Effects of dexamethasone and vitamin D3 on cartilage differentiation in a clonal chondrogenic cell population.

J. Aubin, J. Heersche, A. E. Grigoriadis, 1989, Endocrinology.

The effects of natural and synthetic retinoids on the differentiation of RCJ C5.18 chondrogenic cells.

H. V. von Schroeder, J. Heersche, Y. Hashimoto, 1994, Teratology.

The mode of action of dibutyryl adenosine 3',5'-monophosphate on bone tissue in vitro.

J. Heersche, S. Fedak, G. Aurbach, 1971, The Journal of biological chemistry.

Retinoic acid stimulates 1,25-dihydroxyvitamin D3 binding in rat osteosarcoma cells.

J. Heersche, G. Jones, P. Petkovich, 1984, The Journal of biological chemistry.

Analysis of chondroprogenitor frequency and cartilage differentiation in a novel family of clonal chondrogenic rat cell lines.

J. Aubin, J. Heersche, A. E. Grigoriadis, 1996, Differentiation; research in biological diversity.

Continuously growing bipotential and monopotential myogenic, adipogenic, and chondrogenic subclones isolated from the multipotential RCJ 3.1 clonal cell line.

J. Aubin, J. Heersche, A. E. Grigoriadis, 1990, Developmental biology.

Tri-iodothyronine (T3) and dexamethasone interact to modulate osteoprogenitor cell differentiation in fetal rat calvaria cell cultures.

J. Aubin, C. G. Bellows, J. Heersche, 1995, Bone.

The Role of Phospholipase A2 in Interleukin-1α-mediated Inhibition of Mineralization of the Osteoid Formed by Fetal Rat Calvaria Cells in vitro

J. Aubin, P. Vadas, W. Pruzanski, 1993, Journal of dental research.

Characteristics of in vitro osteoblastic cell loading models.

J. Heersche, N Basso, J N M Heersche, 2002, Bone.

Free and polymerized tubulin in cultured bone cells and Chinese hamster ovary cells: the influence of cold and hormones

J. Aubin, J. Heersche, W. Beertsen, 1982, The Journal of cell biology.

Number, frequency, self‐renewal, and expansion of osteoprogenitor cells (CFU‐O) in subcultured female rat vertebral cell populations

C. G. Bellows, J. Heersche, W. Pei, 2004, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

1,25-Dihydroxyvitamin D3 increases epidermal growth factor receptors and transforming growth factor beta-like activity in a bone-derived cell line.

J. Wrana, J. Heersche, A. Grigoriadis, 1987, The Journal of biological chemistry.

Forskolin has biphasic effects on osteoprogenitor cell differentiation in vitro

J. Aubin, K. Turksen, J. Heersche, 1990, Journal of cellular physiology.

Membrane potential changes, cAMP stimulation and contraction in osteoblast-like UMR 106 cells in response to calcitonin and parathyroid hormone.

J. Aubin, J. Heersche, J. Ferrier, 1988, Bone and mineral.

Proliferation, differentiation and self-renewal of osteoprogenitors in vertebral cell populations from aged and young female rats

C. G. Bellows, J. Heersche, Y. Jia, 2003, Mechanisms of Ageing and Development.

HORMONES AND OTHER FACTORS REGULATING CALCIUM METABOLISM

H. Keutmann, J. Potts, J. Heersche, 1971, Annals of the New York Academy of Sciences.

VEGF‐A expression in osteoclasts is regulated by NF‐κB induction of HIF‐1α

J. Heersche, M. Manolson, Diana P Trebec-Reynolds, 2010, Journal of cellular biochemistry.

Effects of Human a3 and a4 Mutations That Result in Osteopetrosis and Distal Renal Tubular Acidosis on Yeast V-ATPase Expression and Activity*

H. V. von Schroeder, Yeqi Yao, J. Heersche, 2006, Journal of Biological Chemistry.

Identification of Dexamethasone-Dependent Osteoprogenitors in Cell Populations Derived from Adult Human Female Bone

J. Heersche, Y. Yoshimine, W. Pei, 2003, Calcified Tissue International.

Effects of hind limb unloading and reloading on nitric oxide synthase expression and apoptosis of osteocytes and chondrocytes.

J. Heersche, Nick Basso, Johan N M Heersche, 2006, Bone.

Inhibition of osteoclast differentiation by polycyclic aryl hydrocarbons is dependent on cell density and RANKL concentration.

Howard C. Tenenbaum, J. Heersche, M. Manolson, 2005, Biochemical pharmacology.

The effect of vitamin D on bone in vivo.

H. Rasmussen, J. Heersche, G. Jones, 1986, Endocrinology.

Osteoprogenitor viability in cell populations isolated from rat femora is not affected by 24 h storage at 4 degrees C.

J. Heersche, N. Basso, P. Mirkopoulos, 2005, Cryobiology.

Expression of Steroid-Converting Enzymes in Osteoblasts Derived from Rat Vertebrae

B. Strutt, J. Heersche, D. Killinger, 2002, Osteoporosis International.

Ovariectomy of 12-month-old rats: effects on osteoprogenitor numbers in bone cell populations isolated from femur and on histomorphometric parameters of bone turnover in corresponding tibia

C. G. Bellows, J. Heersche, E. S. Elsubeihi, 2007, Cell and Tissue Research.

Metabolic bone disease : cellular and tissue mechanisms

J. Heersche, C. S. Tam, T. Murray, 1989 .

Effect of ovariectomy on dexamethasone- and progesterone-dependent osteoprogenitors in vertebral and femoral rat bone cell populations.

C. G. Bellows, J. Heersche, E. S. Elsubeihi, 2003, Bone.

Effect of age on progesterone receptor expression, and osteoprogenitor proliferation and differentiation in female rat vertebral cell populations.

C. G. Bellows, J. Heersche, Yongheng Jia, 2006, The Journal of endocrinology.

Skeletal response in rats following the implantation of hypercalcemia-producing Leydig cell tumors.

J. Heersche, C. S. Tam, A. Spiegel, 1984, Metabolism: clinical and experimental.

Endothelin-1 promotes osteoprogenitor proliferation and differentiation in fetal rat calvarial cell cultures.

H. V. von Schroeder, J. Payandeh, J. Heersche, 2003, Bone.

Calcitonin‐like effects of forskolin and choleratoxin on surface area and motility of isolated rabbit osteoclasts

J. Heersche, U. Lerner, J. Heersche, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Macrophage Colony Stimulating Factor Increases Bone Resorption in Dispersed Osteoclast Cultures by Increasing Osteoclast Size

J. Heersche, J. Heersche, R. L. Lees, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Uptake of collagenolytic enzymes by bone cells during isolation from embryonic rat calvaria

J. Heersche, J. Sodek, 2006, Calcified Tissue International.

Osteoprogenitor cell differentiation to mature bone‐forming osteoblasts

J. Aubin, J. Heersche, Johan N.M. Heersche, 2000 .

Effects of Human a 3 and a 4 Mutations that Result in Osteopetrosis and Distal Renal Tubular Acidosis on Yeast V-ATPase Expression and Activity *

Yeqi Yao, J. Heersche, M. Manolson, 2006 .

Dexamethasone Inhibits Formation of Osteoclast-like Cells in Bone-marrow Cultures

J. Heersche, J. Heersche, M. Pharoah, 1986, Journal of dental research.

Displacement and translocation of osteoblast‐like cells by osteoclasts

J. Aubin, J. Heersche, J. Ferrier, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Consistent patterns of changing hormone responsiveness during continuous culture of cloned rat calvaria cells

J. Aubin, M. Liebert, J. Heersche, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Electrophysiological responses of osteoclasts to hormones

J. Heersche, J. Ferrier, J. Kanehisa, 1986, Journal of cellular physiology.

The effects of fluoride on osteoblast progenitors In Vitro

J. Aubin, C. G. Bellows, J. Heersche, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Carbonic anhydrase II mRNA expression in individual osteoclasts under “resorbing” and “nonresorbing” conditions

J. Aubin, J. Heersche, J. Sodek, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Resorptive state and cell size influence intracellular pH regulation in rabbit osteoclasts cultured on collagen-hydroxyapatite films.

J. Heersche, J. Heersche, R. L. Lees, 2001, Bone.

Expression of calcitonin receptors during osteoclast differentiation in mouse metatarsals

J. Heersche, I. Tertinegg, J. Heersche, 1989, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Localization of bone sialoprotein (BSP) expression to sites of mineralized tissue formation in fetal rat tissues by in situ hybridization.

J. Wrana, J. Heersche, J. Sodek, 1991, Matrix.

Adhesion patterns and cytoskeleton of rabbit osteoclasts on bone slices and glass

J. Aubin, K. Turksen, M. Opas, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

VEGF‐A expression in osteoclasts is regulated by NF‐κB induction of HIF‐1α

J. Heersche, M. Manolson, Diana P Trebec-Reynolds, 2010, Journal of cellular biochemistry.

The Osteoporosis Primer: Osteoclasts: characteristics and regulation of formation and activity

J. Heersche, M. Manolson, 2000 .

The effects of sodium fluoride on the resorptive activity of isolated osteoclasts

J. Heersche, J. Kanehisa, J. Heersche, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.