A. McDonough

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ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membrane.

M. Sandberg, Anne D. M. Riquier, K. Pihakaski-Maunsbach, 2007, American journal of physiology. Renal physiology.

Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure.

A. McDonough, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Local pH domains regulate NHE3-mediated Na⁺ reabsorption in the renal proximal tubule.

J. Peti-Peterdi, A. McDonough, N. Holstein-Rathlou, 2014, American journal of physiology. Renal physiology.

Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension.

C. Tse, A. McDonough, D. Marsh, 1998, American journal of physiology. Renal physiology.

Thyroid hormone coordinately regulates Na+-K+-ATPase alpha- and beta-subunit mRNA levels in kidney.

A. McDonough, R. Chiu, T. A. Brown, 1988, The American journal of physiology.

Reversible effects of acute hypertension on proximal tubule sodium transporters.

C. Magyar, A. McDonough, N. Holstein-Rathlou, 1998, The American journal of physiology.

Dexamethasone treatment causes resistance to insulin-stimulated cellular potassium uptake in the rat.

J. Youn, A. McDonough, M. Rhee, 2004, American journal of physiology. Cell physiology.

Proximal tubule specific knockout of the Na+/H+ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion

Tong Wang, A. McDonough, M. Tauc, 2013, Journal of molecular medicine.

Skeletal muscle regulates extracellular potassium.

J. Youn, A. McDonough, C. B. Thompson, 2002, American journal of physiology. Renal physiology.

Hypokalemia decreases Na(+)-K(+)-ATPase alpha 2- but not alpha 1-isoform abundance in heart, muscle, and brain.

A. McDonough, C. B. Hensley, K. Azuma, 1991, The American journal of physiology.

Modest dietary K+ restriction provokes insulin resistance of cellular K+ uptake and phosphorylation of renal outer medulla K+ channel without fall in plasma K+ concentration.

J. Youn, E. Babilonia, A. McDonough, 2006, American journal of physiology. Cell physiology.

Role of muscle in regulating extracellular [K+].

J. Youn, A. McDonough, 2005, Seminars in nephrology.

Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways

J. Pollock, A. McDonough, K. Hyndman, 2017, Journal of the American Heart Association.

Independent regulation of in vivo insulin action on glucose versus K(+) uptake by dietary fat and K(+) content.

F. N. Lee, J. Youn, A. McDonough, 2002, Diabetes.

Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp.

J. Youn, A. McDonough, C. Choi, 2001, American journal of physiology. Renal physiology.

Slc26a6 (PAT1) Deletion Downregulates the Apical Na+/H+ Exchanger in the Straight Segment of the Proximal Tubule

A. McDonough, S. Petrovic, M. Soleimani, 2007, American Journal of Nephrology.

Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity.

K. Bernstein, A. McDonough, J. Giani, 2017, Kidney international.

Isoform specificity of cardiac glycosides binding to human Na + ,K + -ATPase α 1 β 1 , α 2 β 1 and α 3 β 1

A. McDonough, G. Scheiner-Bobis, U. Mehlhorn, 2016 .

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

R. Schwinger, W. Bloch, A. McDonough, 2009, European journal of pharmacology.

Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease".

E. Avner, W. Sweeney, A. McDonough, 2012, American journal of physiology. Cell physiology.

Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus.

B. Zlokovic, A. McDonough, J. Mackic, 1993, The Journal of biological chemistry.

Moving the Needle on Hypertension: What Knowledge Is Needed?

Marie E. Latulippe, M. E. Latulippe, A. McDonough, 2019, Nutrition today.

α2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease.

L. Markó, A. McDonough, J. Stegbauer, 2020, Journal of the American Society of Nephrology : JASN.

Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart--right atrium vs left ventricle.

R. Schwinger, A. McDonough, J. Müller-Ehmsen, 2001, Cellular and molecular biology.

Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis.

E. Delpire, J. Youn, A. McDonough, 2014, American journal of physiology. Renal physiology.

Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties.

A. Yu, R. Fenton, S. Bachmann, 2013, American journal of physiology. Cell physiology.

Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron.

E. Delpire, S. Bachmann, A. McDonough, 2012, American journal of physiology. Renal physiology.

abundance along the nephron O transporters' 2 , and H + , K + supplementation on Na -deficient diets with and without NaCl + Effects of K

E. Delpire, S. Bachmann, A. McDonough, 2012 .

Sex-Differences in Solute Transport Along the Nephrons: Effects of Na+ Transport Inhibition.

A. Layton, A. McDonough, Rui Hu, 2020, American journal of physiology. Renal physiology.

Characteristics of antibodies to guinea pig (Na++K+)-adenosine triphosphatase and their use in cell-free synthesis studies

A. Hiatt, A. McDonough, I. Edelman, 2005, The Journal of Membrane Biology.

Impact of casein- versus grain-based diets on rat renal sodium transporters' abundance and regulation.

A. McDonough, L. Veiras, D. Ralph, 2021, Kidney360.

Of mice and men: modeling cardiovascular complexity in diabetes. Focus on "Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart".

H. Patel, A. McDonough, 2014, American journal of physiology. Cell physiology.

Evidence for gut factor in K+ homeostasis.

F. N. Lee, J. Youn, A. McDonough, 2007, American journal of physiology. Renal physiology.

Does membrane trafficking play a role in regulating the sodium/hydrogen exchanger isoform 3 in the proximal tubule?

A. McDonough, D. Biemesderfer, 2003, Current opinion in nephrology and hypertension.

Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention.

J. Verlander, A. McDonough, C. Baylis, 2015, American journal of physiology. Renal physiology.

AMPK activation with AICAR provokes an acute fall in plasma [K+].

A. Marette, J. Youn, D. Zheng, 2008, American journal of physiology. Cell physiology.

In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition.

C. Magyar, A. McDonough, N. Holstein-Rathlou, 1999, American journal of physiology. Renal physiology.

Potassium homeostasis: sensors, mediators, and targets

R. Fenton, A. McDonough, 2022, Pflügers Archiv - European Journal of Physiology.

Low K+ increases Na,K-ATPase abundance in LLC-PK1/Cl4 cells by differentially increasing beta, and not alpha, subunit mRNA.

A. McDonough, C. B. Hensley, D. Putnam, 1990, The Journal of biological chemistry.

Thyroid hormone regulates alpha and alpha + isoforms of Na,K-ATPase during development in neonatal rat brain.

A. McDonough, C. Schmitt, 1988, The Journal of biological chemistry.

Physiologic Relevance of the α2 Isoform of Na,K-ATPase in Muscle and Heart

C. Magyar, A. McDonough, C. B. Hensley, 1994 .

Diuretic response to acute hypertension is blunted during angiotensin II clamp.

A. McDonough, N. Holstein-Rathlou, P. Leong, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

The physiological role of glucagon-like peptide-1 in the regulation of renal function.

A. McDonough, A. Girardi, G. Malnic, 2016, American journal of physiology. Renal physiology.

Effects of ACE inhibition on proximal tubule sodium transport.

J. Klein, D. K. Yip, M. Sandberg, 2006, American journal of physiology. Renal physiology.

Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status.

M. Sandberg, K. Pihakaski-Maunsbach, A. McDonough, 2008, American journal of physiology. Renal physiology.

Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance.

A. McDonough, P. Leong, Li E. Yang, 2007, American journal of physiology. Renal physiology.

How does potassium supplementation lower blood pressure?

A. McDonough, Mien T. X. Nguyen, M. Nguyen, 2012, American journal of physiology. Renal physiology.

Immunodetection of Na,K-ATPase in guinea-pig retinal layers, cornea and lens.

A. McDonough, 1985, Experimental eye research.

Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme

K. Bernstein, A. McDonough, B. Rodriguez-Iturbe, 2015, Hypertension.

Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis.

D. Warnock, R. Chambrey, C. Magyar, 1996, The American journal of physiology.

Nicotine Downregulates α2 Isoform of Na,K-ATPase at the Blood-Brain Barrier and Brain in Rats

B. Zlokovic, A. McDonough, M. Weiss, 1994 .

Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats.

B. Zlokovic, A. McDonough, M. Weiss, 1994, Biochemical and biophysical research communications.

Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension.

C. Tse, A. McDonough, D. Marsh, 1998, The American journal of physiology.

Coordinate adaptations of skeletal muscle and kidney to adjust extracellular [K+] during K+ deficient diet in mice.

A. Mercado, G. Gamba, A. McDonough, 2020, American journal of physiology. Cell physiology.

Renal Na+/H+ exchanger isoforms and their regulation by thyroid hormone.

D. Warnock, R. Chambrey, C. Magyar, 1996, The American journal of physiology.

Amiodarone Decreases Na,K-ATPase α2 and β2 Expression Specifically in Cardiac Ventricle

A. McDonough, J. Sarma, M. Bersohn, 1994 .

Cell‐Specific Actions of the Prostaglandin E‐Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages

B. Koller, T. Coffman, A. McDonough, 2022, Journal of the American Heart Association.

American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte

David M. Pritchard, Michael Camilleri, Gianrico Farrugia, 2003 .

Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits.

J. Youn, A. McDonough, 2017, Physiology.

The sodium pump needs its β subunit

K. Geering, A. McDonough, R. Farley, 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Physiologic Rationale for Multiple Sodium Pump Isoforms

M. Tang, A. McDonough, F. Nakhoul, 1992 .

Cardiovascular beneﬁts associated with higher dietary K (cid:2) vs. lower dietary Na (cid:2) : evidence from population and mechanistic studies

A. McDonough, L. Veiras, D. Ralph, 2017 .

Vascular Control of Kidney Epithelial Transporters.

E. Petretto, T. Coffman, A. McDonough, 2021, American journal of physiology. Renal physiology.

Comparison of subunits of cardiac, brain, and kidney Na+-K+-ATPase.

A. McDonough, C. Schmitt, 1985, The American journal of physiology.

Rapid Hypertensinogenic Effect of Lead: Studies in the Spontaneously Hypertensive Rat

A. McDonough, F. Nakhoul, N. Brautbar, 1992, Toxicology and industrial health.

Differential regulation of sodium pump isoforms in heart.

A. McDonough, C. B. Hensley, K. Azuma, 1992, Seminars in nephrology.

Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II.

R. Carey, K. Kalantari, A. Klibanov, 2017, Journal of the American Society of Nephrology : JASN.

Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II–Induced Hypertension

Y. Iwakura, R. Hoover, A. McDonough, 2016, Hypertension.

Interleukin-17 A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II – Induced Hypertension

Y. Iwakura, R. Hoover, A. McDonough, 2016 .

Chapter 8 Use of Antibodies in the Study of Na+, K+-ATPase Biosynthesis and Structure

A. McDonough, 1984 .

Molecular mechanisms of sodium transport inhibition in proximal tubule during acute hypertension.

C. Magyar, A. McDonough, 2000, Current opinion in nephrology and hypertension.

Redistribution of distal tubule Na+-Cl- cotransporter (NCC) in response to a high-salt diet.

M. Sandberg, A. McDonough, A. B. Maunsbach, 2006, American journal of physiology. Renal physiology.

Redistribution of distal tubule Na (cid:1) -Cl (cid:2) cotransporter (NCC) in response to a high-salt diet

M. Sandberg, A. McDonough, A. B. Maunsbach, 2006 .

Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patterns.

A. McDonough, N. Holstein-Rathlou, Harrison W. Lin, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Thyroid hormone induction of rat myocardial Na(+)-K(+)-ATPase: alpha 1-, alpha 2-, and beta 1-mRNA and -protein levels at steady state.

M. Tang, A. McDonough, C. B. Hensley, 1992, The American journal of physiology.

Developmental and Thyroid Hormone Regulation of Na,K-ATPase Isoforms in the Brain

A. McDonough, C. Schmitt, 1989 .

Enrichment of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles by alkaline extraction.

K. Philipson, A. McDonough, J. Frank, 1987, Biochimica et biophysica acta.

Proximal tubule Na transporter responses are the same during acute and chronic hypertension.

C. Magyar, A. McDonough, N. Holstein-Rathlou, 2000, American journal of physiology. Renal physiology.

Can ENaC regulate ICF as well as ECF volume? Focus on "Osmotic pressure regulates αβγ-rENaC expressed in Xenopus oocytes".

A. McDonough, 1998, American journal of physiology. Cell physiology.

Osmotic pressure regulates abg-rENaC expressed in Xenopus oocytes ’ ’

A. McDonough, 1998 .

Temporal responses of oxidative vs. glycolytic skeletal muscles to K+ deprivation: Na+ pumps and cell cations.

J. Youn, A. McDonough, C. Choi, 1999, American journal of physiology. Cell physiology.

The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension.

C. Magyar, A. McDonough, N. Holstein-Rathlou, 1998, Journal of the American Society of Nephrology : JASN.

Sex differences in solute and water handling in the human kidney: Modeling and functional implications

A. Layton, A. McDonough, Rui Hu, 2021, bioRxiv.

UT-A Urea Transporter Protein in Heart: Increased Abundance During Uremia, Hypertension, and Heart Failure

B. Roberts, J. Sands, A. McDonough, 2001, Circulation research.

Developmental Change in Na,K-ATPase α1 and β1 Expression in Normal and Hypothyroid Rat Renal Cortex

A. McDonough, F. Nakhoul, C. B. Thompson, 2000, American Journal of Nephrology.

Isozymes of dog heart Na+-K+-ATPase are immunologically similar to isozymes in brain.

A. McDonough, C. Schmitt, 1987, The American journal of physiology.

Pretranslational regulation of Na-K-ATPase in cultured canine kidney cells by low K+.

A. McDonough, J. Bowen, 1987, The American journal of physiology.

Antibodies to Na,K-ATPase: Characterization and Use in Cell-Free Synthesis Studies

A. Hiatt, A. McDonough, I. Edelman, 1983 .

Synthesis and translocation of Na(+)-K(+)-ATPase alpha- and beta-subunits to plasma membrane in MDCK cells.

A. McDonough, J. Bowen, A. Mircheff, 1992, The American journal of physiology.

Thyroid hormone specifically regulates skeletal muscle Na+-K+-ATPase α2- and β2-isoforms

M. Tang, A. McDonough, C. B. Hensley, 1993 .

THE BLOOD·BRAIN INTERFACE

B. Zlokovic, A. McDonough, J. Mackic, 1993 .

Expression of Na,K-ATPase at the blood-brain interface.

B. Zlokovic, A. McDonough, J. Mackic, 1993, Advances in experimental medicine and biology.

Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity.

S. Hamm-Alvarez, A. McDonough, P. Leong, 2002, American journal of physiology. Renal physiology.

The Highs and Lows of Potassium Intake in CKD — Does One Size Fit All?

A. McDonough, T. Saritas, A. Terker, 2022 .

The cardiac sodium pump: structure and function

R. Schwinger, K. Philipson, A. McDonough, 2002, Basic Research in Cardiology.

Posttranscriptional upregulation of Na(+)-K(+)-ATPase activity in newborn guinea pig renal cortex.

A. McDonough, E. Guillery, D. J. Huss, 1997, American Journal of Physiology.

Metabolic Basis of Solute Transport

A. McDonough, S. Thomson, 2012 .

Paracellular epithelial sodium transport maximizes energy efficiency in the kidney.

W. Welch, T. Fields, A. Yu, 2016, The Journal of clinical investigation.

Na(+)-K(+)-ATPase alpha 1- and beta 1-subunit degradation: evidence for multiple subunit specific rates.

A. McDonough, D. Putnam, L. Lescale-Matys, 1993, The American journal of physiology.

invited review Skeletal muscle regulates extracellular potassium

J. Youn, A. McDonough, C. B. Thompson, 2002 .

Na,K-ATPase Abundance and Activity in HeLa Cells Transfected with Rat α Isoforms

C. Magyar, A. McDonough, D. Putnam, 1994 .

Ouabain and substrate affinities of human Na+-K+-ATPase α1β1, α2β1, and α3β1when expressed separately in yeast cells

J. Lingrel, R. Schwinger, A. McDonough, 2001 .

Stable potassium isotopes (41K/39K) track transcellular and paracellular potassium transport in biological systems

J. Youn, A. McDonough, C. Spetea, 2022, bioRxiv.

Assembly of the (Na+ + K+)-adenosine triphosphatase. Post-translational membrane integration of the alpha subunit.

A. Hiatt, A. McDonough, I. Edelman, 1984, The Journal of biological chemistry.

Considerations when quantitating protein abundance by immunoblot.

A. McDonough, L. Veiras, Jacqueline N. Minas, 2015, American journal of physiology. Cell physiology.

Local and Downstream Actions of Proximal Tubule Angiotensin II Signaling on Sodium Transporters in the Mouse Nephron.

Jonathan W. Nelson, K. Bernstein, A. McDonough, 2021, American journal of physiology. Renal physiology.

AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.

T. Coffman, J. Schnermann, A. McDonough, 2011, Cell metabolism.

Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles.

A. McDonough, A. B. Maunsbach, P. Leong, 2009, American journal of physiology. Renal physiology.

Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension.

A. McDonough, N. Holstein-Rathlou, P. Leong, 2002, American journal of physiology. Renal physiology.

Mapping subcellular distribution of Na+-K+-ATPase in rat parotid gland.

A. McDonough, T. Kozłowski, A. Mircheff, 1986, The American journal of physiology.

The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease.

K. Bernstein, A. McDonough, J. Giani, 2018, Journal of the American Society of Nephrology : JASN.

Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heart.

Konrad Frank, Erland Erdmann, Jiangnan Wang, 1996, The Journal of clinical investigation.

Isolation of partial cDNAs for rat liver and muscle glycogen phosphorylase isozymes

T. B. Miller, G. Johnson, A. McDonough, 1986, FEBS letters.

Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation.

S. Oparil, W. Cushman, L. Appel, 2020, Hypertension.

Developmental and thyroid hormone regulation of two molecular forms of Na+-K+-ATPase in brain.

A. McDonough, C. Schmitt, 1986, The Journal of biological chemistry.

Molecular cloning and sequence analysis of the (Na+ + K+)-ATPase beta subunit from dog kidney.

R. P. Miller, A. McDonough, B. Horowitz, 1987, Biochimica et biophysica acta.

Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertension.

A. McDonough, A. B. Maunsbach, P. Leong, 2005, Journal of the American Society of Nephrology : JASN.

Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron.

Mehul B. Patel, A. McDonough, S. Crowley, 2016, Cell metabolism.

Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling.

A. McDonough, A. Girardi, G. Malnic, 2015, American journal of physiology. Cell physiology.

Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes.

A. McDonough, A. B. Maunsbach, P. Leong, 2004, American journal of physiology. Renal physiology.

Recent advances in understanding integrative control of potassium homeostasis.

J. Youn, A. McDonough, 2009, Annual review of physiology.

Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes.

A. McDonough, J. Frank, Y. Zhang, 1996, The American journal of physiology.

Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli.

K. Pihakaski-Maunsbach, A. McDonough, Anne Riquier-Brison, 2010, American journal of physiology. Renal physiology.

Renal NHE3 and NaPi2 partition into distinct membrane domains.

A. McDonough, Donna H. Lee, Anne D M Riquier, 2009, American journal of physiology. Cell physiology.

Phenol injury-induced hypertension stimulates proximal tubule Na+/H+ exchanger activity.

A. McDonough, K. Yip, C. Landon, 2006, American journal of physiology. Renal physiology.

ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure—Hypertension and the Proximal Tubule

A. McDonough, 2016, Kidney international reports.

Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition.

E. Delpire, A. McDonough, Mien T. X. Nguyen, 2013, American journal of physiology. Renal physiology.

Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis.

A. Yu, N. Pastor-Soler, A. McDonough, 2017, Journal of the American Society of Nephrology : JASN.

Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice

A. McDonough, J. Giani, M. Mamenko, 2020, Acta physiologica.

Significance of sodium pump isoforms in digitalis therapy.

A. McDonough, R. Farley, J. Wang, 1995, Journal of molecular and cellular cardiology.

Mechanism and Pathophysiology

A. McDonough, T. Le, J. Gigliotti, 2020, Nephrology Self-Assessment Program.

Functional implications of the differences in transporters' abundance along the rat nephron: modeling and analysis.

A. Layton, A. McDonough, Rui Hu, 2019, American journal of physiology. Renal physiology.

Sex and Gender in Renal Health and Function Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis

A. McDonough, Rui Hu, A. Layton, 2022 .

Skeletal Muscle Na,K-ATPase α and β Subunit Protein Levels Respond to Hypokalemic Challenge with Isoform and Muscle Type Specificity*

A. McDonough, C. B. Thompson, 1996, The Journal of Biological Chemistry.

Differential regulation of Na,K-ATPase alpha 1, alpha 2, and beta subunit mRNA and protein levels by thyroid hormone.

A. McDonough, B. Horowitz, C. B. Hensley, 1990, The Journal of biological chemistry.

Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis.

A. Layton, A. McDonough, H. Layton, 2018, American journal of physiology. Renal physiology.

Thyroid hormone specifically regulates skeletal muscle Na(+)-K(+)-ATPase alpha 2- and beta 2-isoforms.

M. Tang, A. McDonough, K K Azuma, 1993, The American journal of physiology.

Glucocorticoids increase sodium pump α2- and β1-subunit abundance and mRNA in rat skeletal muscle

A. McDonough, I. Dørup, C. B. Thompson, 2001 .

Ouabain and substrate affinities of human Na 1 -K 1 -ATPase a 1 b 1 , a 2 b 1 , and a 3 b 1 when expressed separately in yeast cells

J. Lingrel, R. Schwinger, A. McDonough, 2001 .

Role of skeletal muscle sodium pumps in the adaptation to potassium deprivation.

A. McDonough, C. B. Thompson, 1996, Acta physiologica Scandinavica.

Reciprocal regulation of cardiac Na-K-ATPase and Na/Ca exchanger: hypertension, thyroid hormone, development.

C. Magyar, A. McDonough, J. Wang, 1995, The American journal of physiology.

Downstream shift in sodium pump activity along the nephron during acute hypertension.

C. Magyar, A. McDonough, N. Holstein-Rathlou, 2001, Journal of the American Society of Nephrology : JASN.

Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension

A. McDonough, Jiyang Han, L. Veiras, 2016, Hypertension.

Narrative Review: Evolving Concepts in Potassium Homeostasis and Hypokalemia

D. Benos, J. Youn, Megan M. Greenlee, 2009, Annals of Internal Medicine.

Chronic renal injury-induced hypertension alters renal NHE3 distribution and abundance.

V. Campese, A. McDonough, H. Zhong, 2003, American journal of physiology. Renal physiology.

Mechanisms of Pressure Natriuresis

A. McDonough, P. Leong, Li E. Yang, 2003 .

Responses of proximal tubule sodium transporters to acute injury-induced hypertension.

V. Campese, A. McDonough, S. Ye, 2003, American journal of physiology. Renal physiology.

Sex Specific Adaptations to High Salt Diet Preserve Electrolyte Homeostasis with Distinct Sodium Transporter Profiles.

A. McDonough, L. Veiras, D. Ralph, 2021, American journal of physiology. Cell physiology.

Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron

A. McDonough, Jiyang Han, L. Veiras, 2015, Physiological reports.

Impact of Angiotensin II-mediated stimulation of sodium transporters in the nephron assessed by computational modelling.

A. McDonough, A. Edwards, 2019, American journal of physiology. Renal physiology.

Cardiovascular benefits associated with higher dietary K+ vs. lower dietary Na+: evidence from population and mechanistic studies.

A. McDonough, L. Veiras, D. Ralph, 2017, American journal of physiology. Endocrinology and metabolism.

Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension

A. McDonough, Mien T. X. Nguyen, 2015, Hypertension.

The intrarenal generation of angiotensin II is required for experimental hypertension.

K. Bernstein, A. McDonough, Kandarp H. Shah, 2015, Current opinion in pharmacology.

Renal Transporter Activation During Angiotensin-II Hypertension is Blunted in Interferon-&ggr;−/− and Interleukin-17A−/− Mice

D. Harrison, E. Delpire, A. McDonough, 2015, Hypertension.

The absence of intrarenal ACE protects against hypertension.

L. Navar, E. Delpire, K. Bernstein, 2013, The Journal of clinical investigation.

Renal responses to short term non‐pressor AngII ± intrarenal RAS blockade in rats

A. McDonough, Mien T. X. Nguyen, Julie Han, 2013 .

Need to quickly excrete K+? Turn off NCC

J. Youn, A. McDonough, 2013, Kidney international.

Ionic regulation of the biosynthesis of NaK-ATPase subunits.

M. Tang, A. McDonough, L. Lescale-Matys, 1990, Seminars in nephrology.

Downregulation of the Cl-/HCO3-Exchanger Pendrin in Kidneys of Mice with Cystic Fibrosis: Role in the Pathogenesis of Metabolic Alkalosis

A. McDonough, M. Soleimani, K. Zahedi, 2018, Cellular Physiology and Biochemistry.

Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition.

E. Delpire, K. Bernstein, A. McDonough, 2014, Journal of the American Society of Nephrology : JASN.

Renal Generation of Angiotensin II and the Pathogenesis of Hypertension

K. Bernstein, A. McDonough, Kandarp H. Shah, 2014, Current Hypertension Reports.

All human Na+-K+-ATPase α-subunit isoforms have a similar affinity for cardiac glycosides

A. McDonough, J. Velotta, R. Farley, 2001 .

Expression of Na(+)-K(+)-ATPase alpha- and beta-subunits along rat nephron: isoform specificity and response to hypokalemia.

C. Magyar, A. McDonough, Y. Komatsu, 1994, The American journal of physiology.

Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice.

A. McDonough, O. Pochynyuk, Alexis A Gonzalez, 2017, American journal of physiology. Renal physiology.

Connexin 30.3 Is Expressed in the Kidney But Not Regulated by Dietary Salt or High Blood Pressure

K. Willecke, Q. Zheng-Fischhöfer, J. Peti-Peterdi, 2008, Cell communication & adhesion.

Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport.

A. McDonough, P. Leong, Li E. Yang, 2003, Annals of the New York Academy of Sciences.

Blood pressure regulation by the angiotensin type 1 receptor in the proximal tubule

A. McDonough, S. Gurley, Marloes C. van Haaster, 2018, Current opinion in nephrology and hypertension.

Reduced Sodium Pump α1, α3, and β1-Isoform Protein Levels and Na+,K+-ATPase Activity but Unchanged Na+-Ca2+ Exchanger Protein Levels in Human Heart Failure

Konrad Frank, Erland Erdmann, Jiangnan Wang, 1999 .

Proximal tubule specific knockout of the Na+/H+ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion

Tong Wang, A. McDonough, M. Tauc, 2013, Journal of Molecular Medicine.

Exchanger in the Human Heart

E. Erdmann, T. Pressley, A. McDonough, 1996 .

Motoring down the microvilli. Focus on "PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI".

A. McDonough, 2009, American journal of physiology. Cell physiology.

Reversible effects of acute hypertension on proximal tubule sodium transporters.

C. Magyar, A. McDonough, N. Holstein-Rathlou, 1998, American journal of physiology. Cell physiology.

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

A. McDonough, J. Velotta, R. Farley, 2001, American Journal of Physiology - Cell Physiology.

Physiologic rationale for multiple sodium pump isoforms. Differential regulation of alpha 1 vs alpha 2 by ionic stimuli.

M. Tang, A. McDonough, F. Nakhoul, 1992, Annals of the New York Academy of Sciences.

In vivo PTH provokes apical NHE 3 and NaPi 2 redistribution and NaK-ATPase inhibition

C. Magyar, A. McDonough, N. Holstein-Rathlou, 1999 .

Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells.

J. Lingrel, R. Schwinger, A. McDonough, 2001, American journal of physiology. Cell physiology.

Sex differences in renal electrolyte transport

A. McDonough, A. Layton, 2023, Current opinion in nephrology and hypertension.

Estimating In Vivo Potassium Distribution and Fluxes with Stable Potassium Isotopes.

J. Youn, A. McDonough, Y. Oh, 2022, American Journal of Physiology - Cell Physiology.

The Proximal Convoluted Tubule is a Target for the Uroguanylin-regulated Natriuretic Response

D. Witte, J. Lorenz, A. McDonough, 2006, Journal of pediatric gastroenterology and nutrition.

Rationale and design of CAPITA: a RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults.

D. Grobbee, E. Sanders, W. Gruber, 2008, The Netherlands journal of medicine.

Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure.

R. Schwinger, E. Erdmann, A. McDonough, 1999, Circulation.

Glucocorticoids increase sodium pump alpha(2)- and beta(1)-subunit abundance and mRNA in rat skeletal muscle.

A. McDonough, I. Dørup, C. B. Thompson, 2001, American Journal of Physiology - Cell Physiology.

Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K‐ATPase, FXYD2

R. Bouley, A. McDonough, K. Sweadner, 2014, Physiological reports.

Future perspectives: molecular biology and pathophysiology

A. McDonough, 1996 .

Sodium pump isoform expression in heart failure: implication for treatment

R. Schwinger, A. McDonough, R. Farley, 2002, Basic Research in Cardiology.

Reduced Sodium Pumpa1, a3, and b1-Isoform Protein Levels and Na,K-ATPase Activity but Unchanged Na-Ca Exchanger Protein Levels in Human Heart Failure

E. Erdmann, A. McDonough, K. Brixius, 1999 .

Reduced Sodium Pump a 1 , a 3 , and b 1-Isoform Protein Levels and Na 1 , K 1-ATPase Activity but Unchanged Na 1-Ca 2 1 Exchanger Protein Levels in Human Heart Failure

R. Schwinger, E. Erdmann, A. McDonough, 1999 .

Connexin 30.3 Is Expressed in the Kidney But Not Regulated by Dietary Salt or High Blood Pressure

K. Willecke, J. Peti-Peterdi, A. McDonough, 2008, Cell Communication & Adhesion.

The Highs and Lows of Potassium Intake in Chronic Kidney Disease - Does One Size Fit All?

A. McDonough, A. Terker, Turgay Saritas, 2022, Journal of the American Society of Nephrology : JASN.

Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status.

M. Sandberg, K. Pihakaski-Maunsbach, A. McDonough, 2008, American journal of physiology. Renal physiology.

Renal NHE3 and NaPi2 partition into distinct membrane domains.

A. McDonough, Donna H. Lee, Anne D M Riquier, 2009, American journal of physiology. Cell physiology.

Surface and intracellular pools of Na,K-ATPase catalytic and immuno-activities in rat exorbital lacrimal gland.

A. McDonough, M. E. Bradley, A. Mircheff, 1993, Experimental eye research.