M. Gao

发表

Adenylyl Cyclase Type VI Increases Akt Activity and Phospholamban Phosphorylation in Cardiac Myocytes*

J. Feramisco, A. Miyanohara, K. Pestonjamasp, 2008, Journal of Biological Chemistry.

Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts.

A. Firth, J. Yuan, M. Gao, 2011, Journal of the American College of Cardiology.

Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain Reverses Cardiac Dysfunction Caused by Sustained Beta-Adrenergic Receptor Stimulation

M. Gao, T. Guo, H. Hammond, 2016, JACC. Basic to translational science.

Signal peptide increases the efficacy of angiogenic gene transfer for treatment of myocardial ischemia.

M. Gao, H. Hammond, N. C. Lai, 2005, Human gene therapy.

Urocortin 3 Gene Transfer Increases Function of the Failing Murine Heart.

A. Miyanohara, M. Gao, T. Guo, 2019, Human gene therapy.

Intracoronary delivery of an adenovirus encoding fibroblast growth factor-4 in myocardial ischemia: effect of serum antibodies and previous exposure to adenovirus.

N. Dalton, M. Gao, H. Hammond, 2006, Human gene therapy.

Dissociation between regional dysfunction and β-adrenergic receptor signaling in heart failure.

T. Anzai, M. Gao, H. Hammond, 1998, American journal of physiology. Heart and circulatory physiology.

New Signaling Pathways Associated with Increased Cardiac Adenylyl Cyclase 6 Expression: Implications for Possible CHF Therapy

M. Gao, T. Tang, N. Lai, 2008 .

Nitroprusside increases gene transfer associated with intracoronary delivery of adenovirus.

M. Gao, H. Hammond, D. Roth, 2004, Human gene therapy.

Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy.

M. Gao, H. Hammond, D. Entrikin, 1999, Circulation.

Galphaq reduces cAMP production by decreasing Galphas protein abundance.

A. Miyanohara, M. Gao, T. Tang, 2008, Biochemical and biophysical research communications.

Adenylyl Cyclase Increases Survival in Cardiomyopathy

M. Gao, H. Hammond, D. Roth, 2002, Circulation.

Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling

A. Firth, J. Yuan, M. Gao, 2008, Circulation.

Activation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice.

M. Gao, T. Tang, H. Hammond, 2008, Journal of the American College of Cardiology.

beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling.

J. Feramisco, A. Miyanohara, M. Gao, 2010, Cellular signalling.

Significant alteration of liver metabolites by AAV8.Urocortin 2 gene transfer in mice with insulin resistance

M. Gao, T. Guo, H. Hammond, 2019, PloS one.

Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice.

T. Anzai, M. Gao, H. Hammond, 1999, Circulation.

Adenylylcyclase gene transfer increases function of the failing heart.

M. Gao, H. Hammond, Toshiyuki Takahashi, 2006, Human gene therapy.

Intracoronary Adenovirus Encoding Adenylyl Cyclase VI Increases Left Ventricular Function in Heart Failure

N. Dalton, P. Clopton, M. Gao, 2004, Circulation.

Preserved Cardiac Function despite Marked Impairment of cAMP Generation

Hong Wang, M. Gao, T. Tang, 2013, PloS one.

Prospects for gene transfer for clinical heart failure

M. Gao, H. Hammond, T. Tang, 2012, Gene Therapy.

Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer.

M. Gao, H. Hammond, 2011, Journal of molecular and cellular cardiology.

Beneficial Effects of Adenylyl Cyclase Type 6 (AC6) Expression Persist Using a Catalytically Inactive AC6 Mutant

A. Firth, J. Yuan, A. Miyanohara, 2011, Molecular Pharmacology.

Intracoronary Delivery of Adenovirus Encoding Adenylyl Cyclase VI Increases Left Ventricular Function and cAMP-Generating Capacity

K. Urasawa, M. Gao, H. Hammond, 2000, Circulation.

Cardiac-directed expression of a catalytically inactive adenylyl cyclase 6 protects the heart from sustained β-adrenergic stimulation

M. Gao, T. Guo, H. Hammond, 2017, PloS one.

Adenylyl cyclase and G protein receptor kinase expression during development of heart failure.

P. Ping, T. Anzai, M. Gao, 1997, The American journal of physiology.

Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to β–adrenergic stimulation

P. Han, M. Gao, T. Tang, 2006, Basic Research in Cardiology.

G α q Reduces cAMP Production by Decreasing G α s Protein Abundance

A. Miyanohara, M. Gao, T. Tang, 2009 .

Urocortin 2 Gene Transfer for Systolic and Diastolic Dysfunction due to Chronically Increased Left Ventricular Pressure.

M. Gao, H. Hammond, Dimosthenis Giamouridis, 2022, Human gene therapy.

Urocortin 2 Gene Transfer Reduces the Adverse Effects of a Western Diet on Cardiac Function in Mice.

M. Gao, T. Guo, H. Hammond, 2019, Human gene therapy.

Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain (C1C2) Attenuates Deleterious Effects of Pressure Overload.

M. Gao, T. Guo, H. Hammond, 2019, Human gene therapy.

Reduced collagen deposition in infarcted myocardium facilitates induced pluripotent stem cell engraftment and angiomyogenesis for improvement of left ventricular function.

M. Ashraf, Wei Huang, Yigang Wang, 2011, Journal of the American College of Cardiology.

Improved function of the failing rat heart by regulated expression of insulin-like growth factor I via intramuscular gene transfer.

A. Miyanohara, M. Gao, T. Tang, 2012, Human gene therapy.

Comparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer.

A. Miyanohara, M. Gao, T. Tang, 2012, Human gene therapy methods.

Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency

V. A. Huu, M. Gao, T. Guo, 2019, Molecular therapy. Methods & clinical development.

One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance.

T. Ciaraldi, A. Miyanohara, M. Gao, 2016, JCI insight.

Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice

A. Miyanohara, M. Gao, T. Guo, 2015, Human gene therapy.

Intravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice.

N. Dalton, A. Miyanohara, H. Patel, 2013, Human gene therapy.

Dissociation between regional dysfunction and beta-adrenergic receptor signaling in heart failure.

T. Anzai, M. Gao, H. Hammond, 1998, American Journal of Physiology.

Adenylyl Cyclase Type VI Gene Transfer Reduces Phospholamban Expression in Cardiac Myocytes via Activating Transcription Factor 3*

J. Feramisco, M. Gao, T. Tang, 2004, Journal of Biological Chemistry.

Cardiac-directed expression of adenylyl cyclase and heart rate regulation

V. Bhargava, M. Gao, D. Roth, 2003, Basic Research in Cardiology.

Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6.

J. Feramisco, A. Miyanohara, M. Gao, 2009, Biochemical and biophysical research communications.

Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.

M. Gao, T. Tang, T. Guo, 2010, Journal of the American College of Cardiology.

Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical Trial.

Amit N. Patel, C. Yancy, N. Dalton, 2016, JAMA cardiology.

New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.

M. Gao, T. Tang, H. Hammond, 2007, Trends in cardiovascular medicine.

Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation.

A. McCulloch, M. Gao, T. Tang, 2013, Journal of molecular and cellular cardiology.

Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.

A. Firth, J. Yuan, M. Gao, 2011, Biochemical and biophysical research communications.

Adenylyl cyclase type VI corrects cardiac sarcoplasmic reticulum calcium uptake defects in cardiomyopathy.

M. Gao, T. Tang, T. Guo, 2004, American journal of physiology. Heart and circulatory physiology.

Controlled expression of cardiac-directed adenylylcyclase type VI provides increased contractile function.

M. Gao, H. Hammond, D. Roth, 2002, Cardiovascular research.

Increased expression of adenylylcyclase type VI proportionately increases beta-adrenergic receptor-stimulated production of cAMP in neonatal rat cardiac myocytes.

P. Ping, P. Insel, S. Post, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Urocortin2 Gene Transfer Improves Heart Function in Aged Mice.

A. Miyanohara, M. Gao, T. Guo, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal

A. Miyanohara, M. Gao, T. Guo, 2018, JACC. Basic to translational science.

Indirect intracoronary delivery of adenovirus encoding adenylyl cyclase increases left ventricular contractile function in mice.

J. Feramisco, M. Gao, H. Hammond, 2004, American journal of physiology. Heart and circulatory physiology.

Effects of Urocortin 2 Gene Transfer on Glucose Disposal in Insulin-Resistant db/db Mice on Metformin.

M. Gao, T. Guo, H. Hammond, 2023, Human gene therapy.

Increased regional function and perfusion after intracoronary delivery of adenovirus encoding fibroblast growth factor 4: report of preclinical data.

N. Dalton, M. Gao, H. Hammond, 2004, Human gene therapy.

Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.

M. Gao, T. Tang, H. Hammond, 2010, Journal of the American College of Cardiology.

Pressure Overload-induced Cardiac Remodeling and Dysfunction in the Absence of Interleukin 6 in Mice

A. Deng, M. Gao, T. Tang, 2012, Laboratory Investigation.