Seong A. Kang

发表

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

D. Sabatini, M. Yaffe, N. Gray, 2011, Science.

Structure of the human mTOR complex I and its implications for rapamycin inhibition.

D. Sabatini, T. Walz, C. Yip, 2010, Molecular cell.

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

D. Sabatini, N. Gray, W. M. Kuehl, 2009, Cell.

Kang Starvation and Rapamycin mTORC 1 Phosphorylation Sites Encode Their Sensitivity to

Michael B. Yaffe, David M. Sabatini, Benjamin E. Turk, 2013 .

Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer.

D. Sabatini, N. Gray, Qingsong Liu, 2010, Journal of medicinal chemistry.

Discovery of 1-( 4-( 4-Propionylpiperazin-1-yl )-3-( trifluoromethyl ) phenyl )-9-( quinolin-3-yl ) benzo [ h ] [ 1 , 6 ] naphthyridin-2 ( 1 H )-one as a Highly Potent

N. Gray, Qingsong Liu, W. Hur, 2014 .

Development of ATP-competitive mTOR inhibitors.

D. Sabatini, N. Gray, Qingsong Liu, 2012, Methods in molecular biology.

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

S. Gygi, D. Sabatini, Noah Dephoure, 2019, Proceedings of the National Academy of Sciences.

mTORC1 activates PASK-Wdr5 signaling to epigenetically connect the nutrient status with myogenesis

S. Gygi, D. Sabatini, Noah Dephoure, 2017, bioRxiv.

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1*

D. Sabatini, N. Gray, Qingsong Liu, 2009, Journal of Biological Chemistry.

Mammalian Target of Rapamycin ( mTOR ) Inhibitor for Treatment of Cancer

D. Sabatini, N. Gray, Qingsong Liu, 2011 .