M. Keck

发表

Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome

P. Houillier, M. Paulais, M. Bloch-Faure, 2011, Proceedings of the National Academy of Sciences.

ClC-K chloride channels: emerging pathophysiology of Bartter syndrome type 3.

M. Keck, S. Lourdel, J. Teulon, 2015, AJP - Renal Physiology.

Orally Active Aminopeptidase A Inhibitor Prodrugs: Current State and Future Directions

C. Llorens-Cortes, M. Keck, R. Hmazzou, 2019, Current Hypertension Reports.

Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure

M. Keck, C. Combadière, E. Gautier, 2021, Scientific Reports.

A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

C. Llorens-Cortes, M. Keck, D. Bonnet, 2021, Nature communications.

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

R. Chambrey, T. Jentsch, M. Paulais, 2017, Journal of the American Society of Nephrology : JASN.

Monitoring In Vivo Performances of Protein-Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging.

Ki Baek Lee, H. Nozach, F. Beau, 2022, Journal of medicinal chemistry.

Mutations in SLC2A2 reveal hGLUT2 function in pancreatic ß cell development

M. Gall, A. Leturque, É. Brot-Laroche, 2013 .

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

L. Johannes, Serena Petracchini, J. Cintrat, 2022, iScience.

Emergence of Orai3 activity during cardiac hypertrophy.

J. Hulot, M. Keck, M. Trebak, 2015, Cardiovascular research.

A new Kunitz‐type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor

E. De Pauw, G. Mourier, D. Servent, 2021, British journal of pharmacology.

From a Cone Snail Toxin to a Competitive MC4R Antagonist.

G. Mourier, D. Servent, M. Bouvier, 2022, Journal of medicinal chemistry.

First evidence that emerging pinnatoxin-G, a contaminant of shellfish, reaches the brain and crosses the placental barrier.

D. Servent, F. Beau, V. Dive, 2021, The Science of the total environment.

Clinical and Genetic Spectrum of Bartter Syndrome Type 3.

B. Knebelmann, G. Deschênes, S. Lemoine, 2017, Journal of the American Society of Nephrology : JASN.

Mutations in SLC2A2 Gene Reveal hGLUT2 Function in Pancreatic β Cell Development*

R. Scharfmann, M. le Gall, A. Leturque, 2013, The Journal of Biological Chemistry.

CLCNKB mutations causing mild Bartter syndrome profoundly alter the pH and Ca2+ dependence of ClC-Kb channels

M. Keck, S. Lourdel, J. Teulon, 2014, Pflügers Archiv - European Journal of Physiology.

Characterization of the mouse ClC-K1/Barttin chloride channel.

M. Paulais, M. Keck, S. Lourdel, 2013, Biochimica et biophysica acta.

CLCNKB mutations causing mild Bartter syndrome profoundly alter the pH and Ca2+ dependence of ClC-Kb channels

A. Blanchard, M. Keck, S. Lourdel, 2013, Pflügers Archiv - European Journal of Physiology.

Novel CLCNKB Mutations Causing Bartter Syndrome Affect Channel Surface Expression

O. Lahuna, M. Keck, S. Lourdel, 2013, Human mutation.

Heterogeneity in the processing of CLCN5 mutants related to Dent disease

M. Keck, S. Lourdel, J. Teulon, 2011, Human mutation.

Brain renin-angiotensin system blockade with orally active aminopeptidase A inhibitor prevents cardiac dysfunction after myocardial infarction in mice.

O. Agbulut, C. Llorens-Cortes, M. Keck, 2019, Journal of molecular and cellular cardiology.

Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR2- and Orai3- dependent signaling

J. Hulot, M. Keck, F. Atassi, 2019, Scientific Reports.

A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2

L. Johannes, Serena Petracchini, J. Cintrat, 2021, bioRxiv.

A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

C. Llorens-Cortes, M. Keck, X. Iturrioz, 2021, Nature Communications.

QGC606, a best-in-class orally active centrally acting aminopeptidase A inhibitor prodrug, for treating heart failure following myocardial infarction.

O. Agbulut, C. Llorens-Cortes, M. Keck, 2022, The Canadian journal of cardiology.

NI956/QGC006, a Potent Orally Active, Brain-Penetrating Aminopeptidase A Inhibitor for Treating Hypertension

B. Roques, C. Llorens-Cortes, M. Keck, 2019, Hypertension.

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism

C. Llorens-Cortes, M. Keck, N. de Mota, 2021, Frontiers in Pharmacology.

Flahault et al. Stable apelin analog and hypertension 1 LIT01-196, a metabolically stable apelin-17 analog, normalizes blood pressure in hypertensive DOCA-salt rats via a NO synthase-dependent mechanism Short title: Metabolically stable apelin analog and hypertension

C. Llorens-Cortes, M. Keck, Débora S A Mota, 2022 .

Analysis of CLCNKB mutations at dimer‐interface, calcium‐binding site, and pore reveals a variety of functional alterations in ClC‐Kb channel leading to Bartter syndrome

M. Paulais, M. Keck, J. Teulon, 2019, Human mutation.

ClC-K chloride channels: emerging pathophysiology of Bartter syndrome type 3.

M. Keck, S. Lourdel, J. Teulon, 2015, American journal of physiology. Renal physiology.

Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR2- and Orai3- dependent signaling

J. Hulot, M. Keck, F. Atassi, 2019, Scientific Reports.

Emergence of Orai3 activity during cardiac hypertrophy.

J. Hulot, M. Keck, M. Trebak, 2015, Cardiovascular research.

Human Mutation

M. Paulais, M. Keck, J. Teulon, 2020 .